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Wednesday October 22, 2014 - 8:30am - 5:00pm - The Neuroscience Research Building Auditorium
THE INAUGURAL UCLA INTEGRATIVE CENTER FOR NEURAL REPAIR SYMPOSIUM
Sponsored by the BRI, David Geffen School of Medicine, and UC Office of the President
For more details, please click here.
November 4, 2014 - 4pm - The Neuroscience Research Building Auditorium
THE 12th ANNUAL ARNOLD SCHEIBEL DISTINGUISHED POSTDOCTORAL FELLOW IN NEUROSCIENCE LECTURE
JASON STEIN, PhD, from the laboratory of DANIEL GESCHWIND, presents "Evaluating Human Neural Stem Cell Models using a Transcriptomic Rubric".
Hosted by Christopher Evans, Ph.D.
Abstract: Neural stem cells have been adopted to model a wide range of neuropsychiatric conditions in vitro. However, how well such models correspond to in vivo brain has not been evaluated in an unbiased, comprehensive manner. Our work using transcriptomic analyses has enabled comparison of in vitro systems to developing human fetal brain. Using our analysis methods, we observe strong conservation of in vivo gene expression and network architecture in differentiating primary human neural progenitor cells. Conserved modules are enriched in genes associated with autism, supporting the utility of these stem cells for studying neuropsychiatric disease. We also developed and validated a machine learning approach called CoNTExT that identifies the developmental maturity and regional identity of in vitro models. We observed strong differences between in vitro models, including hiPSC-derived neural progenitors from multiple laboratories. This work provides a systems biology framework for evaluating in vitro systems and supports their value in studying the molecular mechanisms of human neurodevelopmental disease.
December 2, 2014 - 1pm - 4pm - The Ackerman Union Grand Ballroom
THE BRAIN RESEARCH INSTITUTE'S 26th ANNUAL NEUROSCIENCE POSTER SESSION
The BRI Neuroscience Poster Session features research from all UCLA neuroscientists, including predoctoral students and postdoctoral fellows and represents continuing efforts to educate investigators about state-of-the-art neuroscience research being conducted at UCLA. Over 175 posters will be presented, many of which will also be presented at the 44nd Annual Meeting of the Society for Neuroscience. BRI Neuroscience Poster Sessions are usually attended by well over 300 neuroscientists comprised of graduate students, postdoctoral fellows, and faculty members representing a multitude of departments on campus.
December 2, 2014 - 4pm - 5pm - The Ackerman Union Grand Ballroom
THE BRAIN RESEARCH INSTITUTE'S 26th ANNUAL NEUROSCIENCE POSTER SESSION DISTINGUISHED LECTURE
RACHEL WONG, Ph.D., Professor in the Department of Biological Structure, University of Washington, Seattle, Washington, presents
"Circuit Assembly, Disassembly and Reassembly in the Vertebrate Retina".
Hosted by Christopher Evans, Ph.D. (firstname.lastname@example.org)
BELOW: The 2013 Poster Session Lecture was presented by Nobel Laureate Dr. Martin Chalfie. Over 300 people attended.