Steven G. Clarke, Ph.D.


Distinguished Professor, Chemistry and Biochemistry

Member, Brain Research Institute

Graduate Program in Biochemistry, Molecular and Structural Biology

Researcher, Biochemistry

Chemical Biology

Awards and Honors:

Princeton University Visiting Fellow, Princeton University

American Chemical Society American Chemical Society/Ralph F. Hirschmann Award in Peptide Chemistry

Alfred P. Sloan Research Fellowship in Chemistry Alfred P. Sloan Research Fellowship in Chemistry

Harvard NSF Predoctoral Fellow


Pomona College Wilson Prize in Chemistry

UCLA Academic Senate Distinguished Teaching Award, including the Eby Award for the Art of Teaching UCLA Academic Senate Distinguished Teaching Award, including the Eby Award for the Art of Teaching

Miller Research Fellow, UC Berkeley Miller Research Fellow, UC Berkeley

Joseph F. Foster Memorial Lecturer, Purdue University

Contact Information

Lab Number: (310) 825-3137 & 825-8121
Work Phone Number: (310) 825-8754

Laboratory Address:

Paul Boyer Hall 628, 637 & 638

Work Address:

Paul Boyer Hall 640


Steven Clarke has been on the faculty of the UCLA Department of Chemistry and Biochemistry since 1978. He is currently a Distinguished Professor of Biochemistry and Director of the UCLA Cellular and Molecular Biology Training Program. He was born in Los Angeles and attended public schools in Altadena and Pasadena, California. He did his undergraduate work at Pomona College in Claremont, majoring in Chemistry and Zoology. During this time, he did undergraduate research at the UCLA Brain Research Institute with Dr. James E. Skinner and Professor Donald Lindsley on neural mechanisms of attention. He was also an NIH fellow in the laboratory of Dr. Peter Mitchell at Glynn Research Laboratories in Bodmin, England studying mitochondrial amino acid transport. He obtained his PhD in Biochemistry and Molecular Biology at Harvard University working as an NSF Fellow with Professor Guido Guidotti on membrane protein-detergent interactions and the identification of the major rat liver mitochondrial polypeptides as enzymes of the urea cycle. He returned to California to do postdoctoral work as a Miller Fellow at the University of California, Berkeley, with Professor Dan Koshland, identifying membrane receptors for bacterial chemotaxis. His research at UCLA has focused on roles of novel protein methyltransferases in aging and biological regulation highlighted by discoveries of the protein L-isoaspartyl repair methyltransferase, the isoprenylcysteine protein methyltransferase, and the protein phosphatase 2A methyltransferase. He has been a visiting scholar at Princeton University (1986-87), the University of Washington (2004-2005), and Vanderbilt University (2015).