Alvaro Sagasti, Ph.D.

Titles

Associate Professor, Molecular, Cell, and Developmental Biology
Member, Brain Research Institute
Cell & Developmental Biology GPB Home Area
Neuroscience GPB Home Area
Neuroscience IDP

Contact Information

Email
sagasti@mcdb.ucla.edu
Phone
Fax Number: 310-206-3987Office Phone Number: 310-206-6147
Address
Mailing Address: Sagasti labP.O. Box 951606 Los Angeles, CA 90095UNITED STATES Office Address: OfficeBSRB 450BUNITED STATES P.O. Box 951606 UNITED STATES

Biography

Dr. Sagasti received his PhD from UCSF, where he worked with Cori Bargmann studying celll specification and left/right asymmetry in the nervous system of the nematode C. elegans. He began his work with zebrafish at the Skirball Institute, NYU Medical Center as a post-doc with Alex Schier. In the summer of 2005 he was a Grass Foundation Fellow at the Marine Biological Labs in Woods Hole, Massachussetts. His work focuses on the development and regeneration of sensory axon arbors in the peripheral nervous system, combining imaging, genetic, and behavioral approaches. He began as a UCLA faculty member in the MCDB department in September 2005.

Publications:

Rieger Sandra, Sagasti Alvaro   Hydrogen peroxide promotes injury-induced peripheral sensory axon regeneration in the zebrafish skin PLoS biology, 2011; 9(5): e1000621.
Rieger Sandra, Wang Fang, Sagasti Alvaro   Time-lapse imaging of neural development: Zebrafish lead the way into the fourth dimension Genesis (New York, N.Y. : 2000), 2011; 214(Pt 6): .
Martin Seanna M, O'Brien Georgeann S, Portera-Cailliau Carlos, Sagasti Alvaro   Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning Development (Cambridge, England), 2010; 137(23): 3985-94.
Grueber Wesley B, Sagasti Alvaro   Self-avoidance and tiling: Mechanisms of dendrite and axon spacing Cold Spring Harbor perspectives in biology, 2010; 2(9): a001750.
O'Brien Georgeann S, Martin Seanna M, Söllner Christian, Wright Gavin J, Becker Catherina G, Portera-Cailliau Carlos, Sagasti Alvaro   Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals Current biology : CB, 2009; 19(24): 2086-90.
O'Brien Georgeann S, Rieger Sandra, Martin Seanna M, Cavanaugh Ann M, Portera-Cailliau Carlos, Sagasti Alvaro   Two-photon axotomy and time-lapse confocal imaging in live zebrafish embryos Journal of visualized experiments : JoVE, 2009; 2(24): pe30.
Richler Esther, Chaumont Severine, Shigetomi Eiji, Sagasti Alvaro, Khakh Baljit S   Tracking transmitter-gated P2X cation channel activation in vitro and in vivo Nature methods, 2008; 5(1): 87-93.
Sagasti, A Guido, MR Raible, DW Schier, AF.   Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors Current biology , 2005; 15(9): 804-14.