Chih-Ming Ho, Ph.D.


Member, Brain Research Institute

Jonsson Comprehensive Cancer Center

Distinguished Research Professor, Mechanical and Aerospace Engineering

Awards and Honors:

American Institute of Aeronautics and Astronautics

American Physical Society

Chinese Academy of Sciences Honorary Professor of Institute of Mechanics

Honorary Professor of Nanjing University of Aeronautics and Astronautics, China

National Tsinghua University Kuo-Nien Honorary Chair Professor

Science Advisor for LNM of Institute of Mechanics, China

Academia Sinica

National Academy of Engineering

Contact Information

Work Phone Number: (310) 825-9993

Mailing Address:

Mechanical and Aerospace Engineering Department
420 Westwood Plaza, Engineering IV
Engineering IV, Room 44-116C
Los Angeles, CA 90095


After receiving his Ph.D. from Johns Hopkins University, Dr. Chih-Ming Ho started his career at the University of Southern California and rose to the rank of full professor. In 1991, he moved to the University of California, Los Angeles (UCLA) to lead the university's establishment of the micro-electro-mechanical-system (MEMS) field, while serving as the founding Director of the Center for Micro Systems. He held the Ben Rich-Lockheed Martin Professor Chair until he retired in 2016, and currently is a UCLA Distinguished Research Professor. Dr. Ho was the Director of the NASA supported Institute for Cell Mimetic Space Exploration (CMISE) and the NIH supported Center for Cell Control (CCC). He served as UCLA Associate Vice Chancellor for Research from 2001 to 2005.

His research interests include phenotypic personalized medicine (PPM), micro/nano fluidics, molecular sensors and turbulence. He was ranked by ISI as one of the top 250 most cited researchers in all engineering categories (2001-2014). In 1997, Dr. Ho was inducted as a member of the National Academy of Engineering. In the next year, he was elected as an Academician of Academia Sinica. He has received a Doctor of Engineering Honoris Causa from Hong Kong University of Science and Technology and Dr. Ho holds ten honorary professorships, including the Einstein Professor from the Chinese Academy of Sciences. Dr. Ho was elected a Fellow of APS, AAAS, AIMBE, AIAA and 3M-Nano Society.

In addition to his academic accomplishments, he has made extensive contributions to many professional societies around the world. He has chaired the Division of Fluid Dynamics (DFD) for the American Physical Society, which is the leading platform in the United States for scientists interested in fundamental fluid dynamics. He was on the advisory board for the AIAA Journal and is a member of the IEEE/ASME JMEMS coordinating Committee. He was an Associate Editor of the ASME Journal of Fluids Engineering and an Associate Editor of the AIAA Journal. He also has served as a Guest Editor for the Annual Review of Fluid Dynamics.

On the international level, he has served on advisory panels to provide assistance to many countries and regions, including China, France, Hong Kong, Israel, Japan, Korea, Switzerland, Taiwan, Thailand, and the United Kingdom on the developments of nano/micro technologies. Dr. Ho also has chaired or served on numerous organizing committees of international conferences on high technology topics.


A selected list of publications:

Wong Ieong, Liu Wenjia, Ho Chih-Ming, Ding Xianting   Continuous Adaptive Population Reduction (CAPR) for Differential Evolution Optimization SLAS technology, 2017; 22(3): 289-305.
Zhu Xiaolu, Gojgini Shiva, Chen Ting-Hsuan, Fei Peng, Dong Siyan, Ho Chih-Ming, Segura Tatiana   Directing three-dimensional multicellular morphogenesis by self-organization of vascular mesenchymal cells in hyaluronic acid hydrogels Journal of biological engineering, 2017; 11(5): 12.
Lee Bai-Yu, Clemens Daniel L, Silva Aleidy, Dillon Barbara Jane, Masleša-Galić Saša, Nava Susana, Ding Xianting, Ho Chih-Ming, Horwitz Marcus A   Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time Nature communications, 2017; 8(5): 14183.
Zhu Xiaolu, Gojgini Shiva, Chen Ting-Hsuan, Teng Fang, Fei Peng, Dong Siyan, Segura Tatiana, Ho Chih-Ming   Three dimensional tubular structure self-assembled by vascular mesenchymal cells at stiffness interfaces of hydrogels Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016; 83(5): 1203-1211.
Lee Juhyun, Fei Peng, Sevag Packard René R, Kang Hanul, Xu Hao, Baek Kyung In, Jen Nelson, Chen Junjie, Yen Hilary, Kuo C-C Jay, Chi Neil C, Ho Chih-Ming, Li Rongsong, Hsiai Tzung K   4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation The Journal of clinical investigation, 2016; 126(8): 3158.
Lee Juhyun, Fei Peng, Packard René R Sevag, Kang Hanul, Xu Hao, Baek Kyung In, Jen Nelson, Chen Junjie, Yen Hilary, Kuo C-C Jay, Chi Neil C, Ho Chih-Ming, Li Rongsong, Hsiai Tzung K   4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation The Journal of clinical investigation, 2016; 126(5): 1679-90.
Zarrinpar Ali, Lee Dong-Keun, Silva Aleidy, Datta Nakul, Kee Theodore, Eriksen Calvin, Weigle Keri, Agopian Vatche, Kaldas Fady, Farmer Douglas, Wang Sean E, Busuttil Ronald, Ho Chih-Ming, Ho Dean   Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform Science translational medicine, 2016; 8(333): 333ra49.
Silva Aleidy, Lee Bai-Yu, Clemens Daniel L, Kee Theodore, Ding Xianting, Ho Chih-Ming, Horwitz Marcus A   Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(15): E2172-9.
Nowak-Sliwinska Patrycja, Weiss Andrea, Ding Xianting, Dyson Paul J, van den Bergh Hubert, Griffioen Arjan W, Ho Chih-Ming   Optimization of drug combinations using Feedback System Control Nature protocols, 2016; 11(2): 302-15.
Guan Zeyi, Lee Juhyun, Jiang Hao, Dong Siyan, Jen Nelson, Hsiai Tzung, Ho Chih-Ming, Fei Peng   Compact plane illumination plugin device to enable light sheet fluorescence imaging of multi-cellular organisms on an inverted wide-field microscope Biomedical optics express, 2016; 7(1): 194-208.
Jin Di, Wong Dennis, Li Junxiang, Luo Zhang, Guo Yiran, Liu Bifeng, Wu Qiong, Ho Chih-Ming, Fei Peng   Compact Wireless Microscope for In-Situ Time Course Study of Large Scale Cell Dynamics within an Incubator Scientific reports, 2015; 5(1): 18483.
Ho Chih-Ming, Shih Daniel Tzu-Bi, Hsiao Chih-Chiang, Huang Shih-Hung, Chang Shwu-Fen, Cheng Wen-Fang   Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis Journal of translational medicine, 2015; 13(1): 367.
Weiss Andrea, Berndsen Robert H, Ding Xianting, Ho Chih-Ming, Dyson Paul J, van den Bergh Hubert, Griffioen Arjan W, Nowak-Sliwinska Patrycja   A streamlined search technology for identification of synergistic drug combinations Scientific reports, 2015; 5(1): 14508.
Mohd Abdul Rashid Masturah Bte, Toh Tan Boon, Silva Aleidy, Nurrul Abdullah Lissa, Ho Chih-Ming, Ho Dean, Chow Edward Kai-Hua   Identification and Optimization of Combinatorial Glucose Metabolism Inhibitors in Hepatocellular Carcinomas Journal of laboratory automation, 2015; 20(4): 423-37.
Weiss Andrea, Ding Xianting, van Beijnum Judy R, Wong Ieong, Wong Tse J, Berndsen Robert H, Dormond Olivier, Dallinga Marchien, Shen Li, Schlingemann Reinier O, Pili Roberto, Ho Chih-Ming, Dyson Paul J, van den Bergh Hubert, Griffioen Arjan W, Nowak-Sliwinska Patrycja   Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer Angiogenesis, 2015; 18(3): 233-44.
Liu Qi, Zhang Cheng, Ding Xianting, Deng Hui, Zhang Daming, Cui Wei, Xu Hongwei, Wang Yingwei, Xu Wanhai, Lv Lei, Zhang Hongyu, He Yinghua, Wu Qiong, Szyf Moshe, Ho Chih-Ming, Zhu Jingde   Preclinical optimization of a broad-spectrum anti-bladder cancer tri-drug regimen via the Feedback System Control (FSC) platform Scientific reports, 2015; 5(3): 11464.
Wang Hann, Lee Dong-Keun, Chen Kai-Yu, Chen Jing-Yao, Zhang Kangyi, Silva Aleidy, Ho Chih-Ming, Ho Dean   Mechanism-independent optimization of combinatorial nanodiamond and unmodified drug delivery using a phenotypically driven platform technology ACS nano, 2015; 9(3): 3332-44.