Hui Sun, Ph.D.


Professor, Physiology

Member, Biochemistry, Biophysics & Structural Biology GPB Home Area

Brain Research Institute

Molecular, Cellular & Integrative Physiology GPB Home Area

Contact Information

Lab Number: 310-206-4018
Office Phone Number: 206-4017

Laboratory Address:

CHS 53-140


Work Address:

CHS 53-140A



Dr. Sun is Professor of Physiology and Ophthalmology in the Department of Physiology and Jules Stein Eye Institute, David Geffen School of Medicine at UCLA. He is also a member of the Jonsson Comprehensive Cancer Center. He received his Ph.D. from Johns Hopkins University in 1998. He came to UCLA in 2003 as an Assistant Professor and received the prestigious Early Career Scientist Award from the Howard Hughes Medical Institute in 2009. He has taught in a variety of courses related to physiology and human diseases at UCLA Medical School, UCLA Dental School and UCLA Graduate School.


Kawaguchi, R., Zhong, M., Kassai, M., Ter-Stepanian, M., and Sun, H.   Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. , Membranes, 2015; 5: 425-453 .
Zhong, M., and Sun, H.   A Genetic Clog in the Vitamin A Transport Machinery, Cell, 2015; 161 (3): 435-437.
Cheng, G., Zhong, M., Kawaguchi, R., Kassai, M., Al-Ubaidi, M., Deng, J., Ter-Stepanian, M., and Sun, H.   Identification of PLXDC1 and PLXDC2 as the Transmembrane Receptors for the Multifunctional Factor PEDF. , eLIFE, 2014; 3: e05401.
Kawaguchi, R., Yu, J., Ter-Stepanian, M., Zhong, M., Guo, C., Yuan, Q., Jin, M., Travis, G.H., Ong, D., and Sun, H.   Receptor-Mediated Cellular Uptake Mechanism that is Coupled to Intracellular Storage, ACS Chemical Biology , 2011; 6: 1041-51.
Sun, H., and Kawaguchi, R.   The Membrane Receptor for Plasma Retinol Binding Protein, a New Type of Cell-Surface Receptor, Int Rev Cell Mol Biol. , 2011; 288(1-41): .
Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., and Sun, H.   A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A, Science, 2007; 315: 820-825.
Yang, Z., Camp, N., Sun, H., Tong, Z., Gibbs, D., Cameron, J., Chen, H., Zhao, Y., Pearson, E., Li, X., Chien, J., DeWan, A., Harmon, J., Bernstein, P., Shridhar, V., Zabriskie, N., Hoh, J., Howes, K., and Zhang, K.   A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration, Science, 2006; 314: 992-993.
Jin, M., Li, S., Moghrabi, W.N., Sun, H., and Travis, G.H.   RPE65 is the retinoid isomerase in bovine retinal pigment epithelium, Cell, 2005; 122: 449-459.
Sun, H Tsunenari, T Yau, KW Nathans, J   The vitelliform macular dystrophy protein defines a new family of chloride channels, Proc. Natl. Acad. Sci. USA, 2002; 99(6): 4008-13.
Sun, H Smallwood, PM Nathans, J   Biochemical defects in ABCR protein variants associated with human retinopathies, Nature Genetics. , 2000; 26(2): 242-6.
Sun, H Macke, JP Nathans, J   Mechanisms of spectral tuning in the mouse green cone pigment, Proc. Natl. Acad. Sci. USA, 1997; 94(16): 8860-5.
Allikmets, R Singh, N Sun, H Shroyer, NF Hutchinson, A Chidambaram, A Gerrard, B Baird, L Stauffer, D Peiffer, A Rattner, A Smallwood, P Li, Y Anderson, KL Lewis, RA Nathans, J Leppert, M Dean, M Lupski, JR   A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy, Nature Genetics. , 1997; 15(3): 236-46.