Hui Sun, Ph.D.


Associate Professor, Physiology

Member, Biochemistry, Biophysics & Structural Biology GPB Home Area

Brain Research Institute

Molecular, Cellular & Integrative Physiology GPB Home Area

Contact Information

Lab Number: 310-206-4018
Office Phone Number: 206-4017

Laboratory Address:

CHS 53-140


Work Address:

CHS 53-140A



Kawaguchi, R., Yu, J., Ter-Stepanian, M., Zhong, M., Guo, C., Yuan, Q., Jin, M., Travis, G.H., Ong, D., and Sun, H.   Receptor-Mediated Cellular Uptake Mechanism that is Coupled to Intracellular Storage, ACS Chemical Biology , 2011; 6: 1041-51.
Sun, H., and Kawaguchi, R.   The Membrane Receptor for Plasma Retinol Binding Protein, a New Type of Cell-Surface Receptor, Int Rev Cell Mol Biol. , 2011; 288(1-41): .
Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., and Sun, H.   A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A, Science, 2007; 315: 820-825.
Yang, Z., Camp, N., Sun, H., Tong, Z., Gibbs, D., Cameron, J., Chen, H., Zhao, Y., Pearson, E., Li, X., Chien, J., DeWan, A., Harmon, J., Bernstein, P., Shridhar, V., Zabriskie, N., Hoh, J., Howes, K., and Zhang, K.   A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration, Science, 2006; 314: 992-993.
Jin, M., Li, S., Moghrabi, W.N., Sun, H., and Travis, G.H.   RPE65 is the retinoid isomerase in bovine retinal pigment epithelium, Cell, 2005; 122: 449-459.
Sun, H Tsunenari, T Yau, KW Nathans, J   The vitelliform macular dystrophy protein defines a new family of chloride channels, Proc. Natl. Acad. Sci. USA, 2002; 99(6): 4008-13.
Sun, H Nathans, J   Mechanistic studies of ABCR, the ABC transporter in photoreceptor outer segments responsible for autosomal recessive Stargardt disease, J Bioenerg Biomembr, 2001; 33(6): 523-30.
Sun, H Nathans, J   ABCR, the ATP-binding cassette transporter responsible for Stargardt macular dystrophy, is an efficient target of all-trans-retinal-mediated photooxidative damage in vitro. Implications for retinal disease, The Journal of Biological Chemistry. , 2001; 276(15): 11766-74.
Sun, H Smallwood, PM Nathans, J   Biochemical defects in ABCR protein variants associated with human retinopathies, Nature Genetics. , 2000; 26(2): 242-6.
Sun, H Nathans, J   ABCR: rod photoreceptor-specific ABC transporter responsible for Stargardt disease, Methods in enzymology. , 2000; 315: 879-97.
Sun, H Molday, RS Nathans, J   Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease, The Journal of Biological Chemistry. , 1999; 274(12): 8269-81.
Sun, H Nathans, J   Stargardt's ABCR is localized to the disc membrane of retinal rod outer segments, Nature Genetics. , 1997; 17(1): 15-6.
Sun, H Macke, JP Nathans, J   Mechanisms of spectral tuning in the mouse green cone pigment, Proc. Natl. Acad. Sci. USA, 1997; 94(16): 8860-5.
Allikmets, R Singh, N Sun, H Shroyer, NF Hutchinson, A Chidambaram, A Gerrard, B Baird, L Stauffer, D Peiffer, A Rattner, A Smallwood, P Li, Y Anderson, KL Lewis, RA Nathans, J Leppert, M Dean, M Lupski, JR   A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy, Nature Genetics. , 1997; 15(3): 236-46.