
Juan Carlos G. Marvizón, Ph.D.
Titles
Member, Brain Research Institute
Adjunct Professor, Medicine
Vatche and Tamar Manoukian Division of Digestive Diseases
CURE: Digestive Diseases Research Center
Contact Information
Email
marvizon@g.ucla.edu Phone
Cell-phone Number:
(310) 384 7535
Fax Number: (310) 268 4963
Work Phone Number: (310) 478 3711 extension 41850
Fax Number: (310) 268 4963
Work Phone Number: (310) 478 3711 extension 41850
Address
Work Address:
OfficeVA Greater Los Angeles Healthcare System
11301 Wilshire Blvd.
Los Angeles, CA 90073
UNITED STATES
Publications
A selected list of publications:
Chen Wenling, Ennes Helena S, McRoberts James A, Marvizón Juan Carlos
Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced
substance P release in the rat spinal cord
Neuropharmacology,
2018; 128:
255-268.
Walwyn Wendy M, Chen Wenling, Kim Hyeyoung, Minasyan Ani, Ennes Helena S, McRoberts James A, Marvizón Juan Carlos G
Sustained Suppression of Hyperalgesia during Latent Sensitization by
μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of
Constitutive Activity
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2016; 36(1):
204-21.
Marvizon Juan Carlos, Walwyn Wendy, Minasyan Ani, Chen Wenling, Taylor Bradley K
Latent sensitization: a model for stress-sensitive chronic pain
Current protocols in neuroscience,
2015; 71(1):
9.50.1-14.
Chen Wenling, Walwyn Wendy, Ennes Helena S, Kim Hyeyoung, McRoberts James A, Marvizón Juan Carlos G
BDNF released during neuropathic pain potentiates NMDA receptors in
primary afferent terminals
The European journal of neuroscience,
2014; 39(9):
1439-54.
Zhang Guohua, Chen Wenling, Marvizón Juan Carlos G
Src family kinases mediate the inhibition of substance P release in
the rat spinal cord by μ-opioid receptors and GABA(B) receptors, but
not α2 adrenergic receptors
The European journal of neuroscience,
2010; 32(6):
963-73.
Zhang Guohua, Chen Wenling, Lao Lijun, Marvizón Juan Carlos G
Cannabinoid CB1 receptor facilitation of substance P release in the
rat spinal cord, measured as neurokinin 1 receptor internalization
The European journal of neuroscience,
2010; 31(2):
225-37.
Marvizón Juan Carlos G, Chen Wenling, Murphy Niall
Enkephalins, dynorphins, and beta-endorphin in the rat dorsal horn: an
immunofluorescence colocalization study
The Journal of comparative neurology,
2009; 517(1):
51-68.
Chen Wenling, Song Bingbing, Zhang Guohua, Marvizón Juan Carlos G
Effects of veratridine and high potassium on micro-opioid receptor
internalization in the rat spinal cord: stimulation of opioid release
versus inhibition of internalization
Journal of neuroscience methods,
2008; 170(2):
285-93.
Chen Wenling, Song Bingbing, Marvizón Juan Carlos G
Inhibition of opioid release in the rat spinal cord by alpha2C
adrenergic receptors
Neuropharmacology,
2008; 54(6):
944-53.
Lao Lijun, Song Bingbing, Chen Wenling, Marvizón Juan Carlos G
Noxious mechanical stimulation evokes the segmental release of opioid
peptides that induce mu-opioid receptor internalization in the
presence of peptidase inhibitors
Brain research,
2008; 1197(6):
85-93.
Chen Wenling, Song Bingbing, Lao Lijun, Pérez Orlando A, Kim Woojae, Marvizón Juan Carlos G
Comparing analgesia and mu-opioid receptor internalization produced by
intrathecal enkephalin: requirement for peptidase inhibition
Neuropharmacology,
2007; 53(5):
664-76.
Song Bingbing, Chen Wenling, Marvizón Juan Carlos G
Inhibition of opioid release in the rat spinal cord by serotonin
5-HT(1A) receptors
Brain research,
2007; 1158(5):
57-62.
Bradesi Sylvie, Kokkotou Efi, Simeonidis Simos, Patierno Simona, Ennes Helena S, Mittal Yash, McRoberts James A, Ohning Gordon, McLean Peter, Marvizon Juan Carlos, Sternini Catia, Pothoulakis Charalabos, Mayer Emeran A
The role of neurokinin 1 receptors in the maintenance of visceral
hyperalgesia induced by repeated stress in rats
Gastroenterology,
2006; 130(6):
1729-42.
Cottrell Graeme S, Roosterman Dirk, Marvizon Juan-Carlos, Song B, Wick Elizabeth, Pikios Stella, Wong Helen, Berthelier Claire, Tang Yat, Sternini Catia, Bunnett Nigel W, Grady Eileen F
Localization of calcitonin receptor-like receptor and receptor
activity modifying protein 1 in enteric neurons, dorsal root ganglia,
and the spinal cord of the rat
The Journal of comparative neurology,
2005; 490(3):
239-55.
Kondo Ichiro, Marvizon Juan Carlos G, Song Bingbing, Salgado Frances, Codeluppi Simone, Hua Xiao-Ying, Yaksh Tony L
Inhibition by spinal mu- and delta-opioid agonists of afferent-evoked
substance P release
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2005; 25(14):
3651-60.
Marvizon Juan Carlos G, Wang Xueren, Lao Li-Jun, Song Bingbing
Effect of peptidases on the ability of exogenous and endogenous
neurokinins to produce neurokinin 1 receptor internalization in the
rat spinal cord
British journal of pharmacology,
2003; 140(8):
1389-98.
Song Bingbing, Marvizón Juan Carlos G
Dorsal horn neurons firing at high frequency, but not primary
afferents, release opioid peptides that produce micro-opioid receptor
internalization in the rat spinal cord
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2003; 23(27):
9171-84.
Song Bingbing, Marvizón Juan Carlos G
Peptidases prevent mu-opioid receptor internalization in dorsal horn
neurons by endogenously released opioids
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2003; 23(5):
1847-58.
Wang Xueren, Marvizón Juan Carlos G
Time-course of the internalization and recycling of neurokinin 1
receptors in rat dorsal horn neurons
Brain research,
2002; 944(1-2):
239-47.
Marvizón Juan Carlos G, McRoberts James A, Ennes Helena S, Song Bingbing, Wang Xueren, Jinton Lisa, Corneliussen Brit, Mayer Emeran A
Two N-methyl-D-aspartate receptors in rat dorsal root ganglia with
different subunit composition and localization
The Journal of comparative neurology,
2002; 446(4):
325-41.
Lever I J, Bradbury E J, Cunningham J R, Adelson D W, Jones M G, McMahon S B, Marvizón J C, Malcangio M
Brain-derived neurotrophic factor is released in the dorsal horn by
distinctive patterns of afferent fiber stimulation
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2001; 21(12):
4469-77.
McRoberts J A, Coutinho S V, Marvizón J C, Grady E F, Tognetto M, Sengupta J N, Ennes H S, Chaban V V, Amadesi S, Creminon C, Lanthorn T, Geppetti P, Bunnett N W, Mayer E A
Role of peripheral N-methyl-D-aspartate (NMDA) receptors in visceral
nociception in rats
Gastroenterology,
2001; 120(7):
1737-48.
Marvizón J C, Grady E F, Waszak-McGee J, Mayer E A
Internalization of mu-opioid receptors in rat spinal cord slices
Neuroreport,
1999; 10(11):
2329-34.
Marvizón J C, Grady E F, Stefani E, Bunnett N W, Mayer E A
Substance P release in the dorsal horn assessed by receptor
internalization: NMDA receptors counteract a tonic inhibition by
GABA(B) receptors
The European journal of neuroscience,
1999; 11(2):
417-26.
Marvizón J C, Eskandari S, Ennes H S, Mayer E A
Substance P induces brief, localized increase in [Ca2+]i in dorsal
horn neurons
Neuroreport,
1998; 9(15):
3369-74.
Marvizón J C, Martínez V, Grady E F, Bunnett N W, Mayer E A
Neurokinin 1 receptor internalization in spinal cord slices induced by
dorsal root stimulation is mediated by NMDA receptors
The Journal of neuroscience : the official journal of the Society for Neuroscience,
1997; 17(21):
8129-36.
Marvizón J C, Baudry M
Allosteric interactions and modulator requirement for NMDA receptor
function
European journal of pharmacology,
1994; 269(2):
165-75.
Marvizón J C, Baudry M
[3H]dizocilpine association kinetics distinguish stimulatory and
inhibitory polyamine sites of N-methyl-D-aspartate receptors
Journal of neurochemistry,
1994; 63(3):
963-71.
Lewin A H, Skolnick P, Marvizon J C, Paul I A, Bowen J P
Requirements for high affinity binding of glycine analogs to the
glycine site of the NMDA receptor complex
European journal of pharmacology,
1993; 247(1):
1-10.
Marvizón J C, Baudry M
Receptor activation by two agonists: analysis by nonlinear regression
and application to N-methyl-D-aspartate receptors
Analytical biochemistry,
1993; 213(1):
3-11.
Shahi K, Marvizon J C, Baudry M
High concentrations of glycine induce long-lasting changes in synaptic
efficacy in rat hippocampal slices
Neuroscience letters,
1993; 149(2):
185-8.
Marvizón J C, Baudry M
NMDA receptor activation by spermine requires glutamate but not
glycine
European journal of pharmacology,
1993; 244(1):
103-4.
Ruiz-Gómez A, Fernández-Shaw C, Morato E, Marvizón J C, Vázquez J, Valdivieso F, Mayor F
Sulfhydryl groups modulate the allosteric interaction between glycine
binding sites at the inhibitory glycine receptor
Journal of neurochemistry,
1991; 56(5):
1690-7.
Marvizón J C, Skolnick P
An endogenous modulator of N-methyl-D-aspartate receptor-coupled
glycine receptors
European journal of pharmacology,
1990; 188(1):
23-32.
Ruiz-Gómez A, García-Calvo M, Vázquez J, Marvizón J C, Valdivieso F, Mayor F
Thermodynamics of agonist and antagonist interaction with the
strychnine-sensitive glycine receptor
Journal of neurochemistry,
1989; 52(6):
1775-80.
Marvizón J C, Lewin A H, Skolnick P
1-Aminocyclopropane carboxylic acid: a potent and selective ligand for
the glycine modulatory site of the N-methyl-D-aspartate receptor
complex
Journal of neurochemistry,
1989; 52(3):
992-4.
Skolnick P, Marvizón J C, Jackson B W, Monn J A, Rice K C, Lewin A H
Blockade of N-methyl-D-aspartate induced convulsions by
1-aminocyclopropanecarboxylates
Life sciences,
1989; 45(18):
1647-55.
Marvizón J C, Skolnick P
Anion regulation of [3H]strychnine binding to glycine-gated chloride
channels is explained by the presence of two anion binding sites
Molecular pharmacology,
1988; 34(6):
806-13.
Alonso T, Morgan R O, Marvizon J C, Zarbl H, Santos E
Malignant transformation by ras and other oncogenes produces common
alterations in inositol phospholipid signaling pathways
Proceedings of the National Academy of Sciences of the United States of America,
1988; 85(12):
4271-5.
Marvizón J C, Skolnick P
[3H]glycine binding is modulated by Mg2+ and other ligands of the NMDA
receptor-cation channel complex
European journal of pharmacology,
1988; 151(1):
157-8.
Marvizón J C, Skolnick P
Enhancement of t-[35S]butylbicyclophosphorothionate and [3H]strychnine
binding by monovalent anions reveals similarities between
gamma-aminobutyric acid- and glycine-gated chloride channels
Journal of neurochemistry,
1988; 50(5):
1632-9.
Marvizón J C, García Calvo M, Vázquez J, Mayor F, Ruíz Gómez A, Valdiviesco F, Benavides J
Activation and inhibition of 3H-strychnine binding to the glycine
receptor by Eccles' anions: modulatory effects of cations
Molecular pharmacology,
1986; 30(6):
598-602.
Marvizón J C, Vázquez J, García Calvo M, Mayor F, Ruíz Gómez A, Valdivieso F, Benavides J
The glycine receptor: pharmacological studies and mathematical
modeling of the allosteric interaction between the glycine- and
strychnine-binding sites
Molecular pharmacology,
1986; 30(6):
590-7.
Marvizon J C, Rumigny J F, Benedetti M S, Gomeni C, Benavides J
Glycine binding to rat CNS membranes: possible cooperative
interaction
Advances in biochemical psychopharmacology,
1983; 37(6):
15-22.
Marvizón J G, Mayor F, Aragón M C, Giménez C, Valdivieso F
L-Aspartate transport into plasma membrane vesicles derived from rat
brain synaptosomes
Journal of neurochemistry,
1981; 37(6):
1401-6.
Mayor F, Marvizón J G, Aragón M C, Gimenez C, Valdivieso F
Glycine transport into plasma-membrane vesicles derived from rat brain
synaptosomes
The Biochemical journal,
1981; 198(3):
535-41.
Aragón M C, Giménez C, Mayor F, Marvizón J G, Valdivieso F
Tyrosine transport by membrane vesicles isolated from rat brain
Biochimica et biophysica acta,
1981; 646(3):
465-70.