Patricia I. Dickson, M.D.


Associate Professor In-Residence, David Geffen School of Medicine at UCLA
Assistant Professor, MEDICAL GENETICS
Member, CTSI
Child Health Research
Neuroscience GPB Home Area
Assistant Professor In-Residence, Brain Research Institute

Contact Information

Fax Number: (310) 328-9921 (310) 782-2999Work Phone Number: (310) 222-3756 (310) 222-4145
Work Address: 1124 West Carson StreetTorrance, CA UNITED STATES


Vite Charles H, Nestrasil Igor, Mlikotic Anton, Jens Jackie K, Snella Elizabeth M, Gross William, Shapiro Elsa G, Kovac Victor, Provenzale James M, Chen Steven, Le Steven Q, Kan Shih-hsin, Banakar Shida, Wang Raymond Y, Haskins Mark E, Ellinwood N Matthew, Dickson Patricia I   Features of brain MRI in dogs with treated and untreated mucopolysaccharidosis type I Comparative medicine, 2013; 63(2): 163-73.
Vera Moin, Lester Thomas, Zhao Bin, Tiger Pascale, Clarke Scott, Tippin Brigette L, Passage Merry B, Le Steven Q, Femenia Javier, Lemontt Jeffrey F, Kakkis Emil D, Dickson Patricia I   Mannose 6-phosphate conjugation is not sufficient to allow induction of immune tolerance to phenylalanine ammonia-lyase in dogs JIMD reports, 2013; 8(2): 63-72.
Tippin Brigette L, Troitskaya Larisa, Kan Shih-hsin, Todd Amanda K, Le Steven Q, Dickson Patricia I   Biochemical characterization of fluorescent-labeled recombinant human alpha-L-iduronidase in vitro Biotechnology and applied biochemistry, 2012; 58(6): 391-6.
Dickson Patricia I, Ellinwood N Matthew, Brown Jillian R, Witt Robert G, Le Steven Q, Passage Merry B, Vera Moin U, Crawford Brett E   Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I Molecular genetics and metabolism, 2012; 106(1): 68-72.
Chen Agnes, Vogler Carole, McEntee Michael, Hanson Stephen, Ellinwood N Matthew, Jens Jackie, Snella Elizabeth, Passage Merry, Le Steven, Guerra Catalina, Dickson Patricia   Glycosaminoglycan storage in neuroanatomical regions of mucopolysaccharidosis I dogs following intrathecal recombinant human iduronidase APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2011; 119(8): 513-21.
Dickson Patricia I, Chen Agnes H   Intrathecal enzyme replacement therapy for mucopolysaccharidosis I: translating success in animal models to patients Current pharmaceutical biotechnology, 2011; 12(6): 946-55.
Dickson Patricia I, Hanson Stephen, McEntee Michael F, Vite Charles H, Vogler Carole A, Mlikotic Anton, Chen Agnes H, Ponder Katherine P, Haskins Mark E, Tippin Brigette L, Le Steven Q, Passage Merry B, Guerra Catalina, Dierenfeld Ashley, Jens Jackie, Snella Elizabeth, Kan Shih-Hsin, Ellinwood N Matthew   Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I Molecular genetics and metabolism, 2010; 101(2-3): 115-22.
Ezra Navid, Tetteh Beatrice, Diament Michael, Jonas Adam J, Dickson Patricia   Hereditary multiple exostoses with spine involvement in a 4-year-old boy American journal of medical genetics. Part A, 2010; 152A(5): 1264-7.
Chen Agnes, Dickson Patricia   Intrathecal enzyme replacement therapy to treat spinal cord compression in mucopolysaccharidosis: Overview and rationale Journal of pediatric rehabilitation medicine, 2010; 3(1): 7-11.
Dierenfeld AD, McEntee MF, Passage M, Le S, Jens JK, Snella EM, Kline KL, Parkes JD, Ware WA, Moran LE, Wengert JA, Whitley RD, Betts DM, Boal AM, Riedesel EA, Gross W, Ellinwood NM, Dickson PI   Replacing the enzyme α-L-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I, Science Translational Medicine, 2010; 2(60): ra89.
Passage M B, Krieger A W, Peinovich M C, Lester T, Le S Q, Dickson P I, Kakkis E D   Continuous infusion of enzyme replacement therapy is inferior to weekly infusions in MPS I dogs Journal of inherited metabolic disease, 2009; 110(3): .
Carlstrom Lucas P, Jens Jackie K, Dobyns Marley E, Passage Merry, Dickson Patricia I, Ellinwood N Matthew   Inadvertent propagation of factor VII deficiency in a canine mucopolysaccharidosis type I research breeding colony Comparative medicine, 2009; 59(4): 378-82.
Dickson Patricia, Peinovich Maryn, McEntee Michael, Lester Thomas, Le Steven, Krieger Aimee, Manuel Hayden, Jabagat Catherine, Passage Merry, Kakkis Emil D   Immune tolerance improves the efficacy of enzyme replacement therapy in canine mucopolysaccharidosis I The Journal of clinical investigation, 2008; 118(8): 2868-76.
Munoz-Rojas Maria-Veronica, Vieira Taiane, Costa Ronaldo, Fagondes Simone, John Angela, Jardim Laura Bannach, Vedolin Leonardo M, Raymundo Marcia, Dickson Patricia I, Kakkis Emil, Giugliani Roberto   Intrathecal enzyme replacement therapy in a patient with mucopolysaccharidosis type I and symptomatic spinal cord compression American journal of medical genetics. Part A, 2008; 146A(19): 2538-44.
Dickson Patricia, McEntee Michael, Vogler Carole, Le Steven, Levy Beth, Peinovich Maryn, Hanson Stephen, Passage Merry, Kakkis Emil   Intrathecal enzyme replacement therapy: successful treatment of brain disease via the cerebrospinal fluid Molecular genetics and metabolism, 2007; 91(1): 61-8.
Belichenko P V, Dickson P I, Passage M, Jungles S, Mobley W C, Kakkis E D   Penetration, diffusion, and uptake of recombinant human alpha-L-iduronidase after intraventricular injection into the rat brain Molecular genetics and metabolism, 2005; 86(1-2): 141-9.
Dickson Patricia I, Briones Norman Y, Baylen Barry G, Jonas Adam J, French Samuel W, Lin Henry J   Costello syndrome with pancreatic islet cell hyperplasia American journal of medical genetics. Part A, 2004; 130A(4): 402-5.
Kakkis E, McEntee M, Vogler C, Le S, Levy B, Belichenko P, Mobley W, Dickson P, Hanson S, Passage M   Intrathecal enzyme replacement therapy reduces lysosomal storage in the brain and meninges of the canine model of MPS I Molecular genetics and metabolism, 2004; 83(1-2): 163-74.
Joyce James J, Dickson Patricia I, Qi Ning, Noble Julie E, Raj J Usha, Baylen Barry G   Normal right and left ventricular mass development during early infancy The American journal of cardiology, 2004; 93(6): 797-801.