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S. Thomas Carmichael, M.D., Ph.D.
Member, Brain Research Institute
Neuroscience GPB Home Area
Member, Brain Research Institute
Neuroscience GPB Home Area
PhoneOffice Phone Number: 310-206-0550 310-794-1195
AddressWork Address: 710 Westwood PlazaLos Angeles, CA 90095UNITED STATES
BiographyS. Thomas (Tom) Carmichael is a neurologist and neuroscientist at the David Geffen School of Medicine at UCLA. Dr. Carmichael is Professor and Vice Chair for Research in the Neurology Department, with active laboratory and clinical interests in stroke and neurorehabilitation, and brain repair after injury. He received his M.D. and Ph.D. degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident in 1997-1998. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001, studying mechanisms of axonal sprouting, with a clinical emphasis on neurorehabilitation and stroke. He has been on the UCLA faculty since 2001. Dr. Carmichael¬ís laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the Neurorehabilitation and Stroke clinical services at UCLA.
Carmichael S Thomas Brain Excitability in Stroke: The Yin and Yang of Stroke Progression Archives of neurology, 2011; 23(43): .
Clarkson Andrew N, Overman Justine J, Zhong Sheng, Mueller Rudolf, Lynch Gary, Carmichael S Thomas AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(10): 3766-75.
Savitz Sean I, Chopp Michael, Deans Robert, Carmichael S T, Phinney Donald, Wechsler Larry Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II Stroke; a journal of cerebral circulation, 2011; 42(3): 825-9.
Li Songlin, Overman Justine J, Katsman Diana, Kozlov Serguei V, Donnelly Christopher J, Twiss Jeffery L, Giger Roman J, Coppola Giovanni, Geschwind Daniel H, Carmichael S Thomas An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke Nature neuroscience, 2010; 13(12): 1496-504.
Clarkson Andrew N, Huang Ben S, Macisaac Sarah E, Mody Istvan, Carmichael S Thomas Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke Nature, 2010; 468(7321): 305-9.
Mostany Ricardo, Chowdhury Tara G, Johnston David G, Portonovo Shiva A, Carmichael S Thomas, Portera-Cailliau Carlos Local hemodynamics dictate long-term dendritic plasticity in peri-infarct cortex The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(42): 14116-26.
Carmichael S Thomas Targets for neural repair therapies after stroke Stroke; a journal of cerebral circulation, 2010; 41(10 Suppl): S124-6.
Zhong Jin, Chan Albert, Morad Leeron, Kornblum Harley I, Fan Guoping, Carmichael S Thomas Hydrogel Matrix to Support Stem Cell Survival After Brain Transplantation in Stroke Neurorehabilitation and neural repair, 2010; .
Benowitz Larry I, Carmichael S Thomas Promoting axonal rewiring to improve outcome after stroke Neurobiology of disease, 2010; 37(2): 259-66.
Carmichael S Thomas Translating the frontiers of brain repair to treatments: starting not to break the rules Neurobiology of disease, 2010; 37(2): 237-42.
Clarkson Andrew N, Carmichael S Tomas Cortical excitability and post-stroke recovery Biochemical Society transactions, 2009; 37(Pt 6): 1412-4.
Harris N G, Carmichael S T, Hovda D A, Sutton R L Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited Journal of neuroscience research, 2009; 87(13): 2937-50.
Sozmen Elif G, Kolekar Arunima, Havton Leif A, Carmichael S Thomas A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates Journal of neuroscience methods, 2009; 180(2): 261-72.
Chow David K, Groszer Matthias, Pribadi Mochtar, Machniki Michal, Carmichael S Thomas, Liu Xin, Trachtenberg Joshua T Laminar and compartmental regulation of dendritic growth in mature cortex Nature neuroscience, 2009; 12(2): 116-8.
Gregorian Caroline, Nakashima Jonathan, Le Belle Janel, Ohab John, Kim Rachel, Liu Annie, Smith Kate Barzan, Groszer Matthias, Garcia A Denise, Sofroniew Michael V, Carmichael S Thomas, Kornblum Harley I, Liu Xin, Wu Hong Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(6): 1874-86.
Carmichael S Thomas, Vespa Paul M, Saver Jeffery L, Coppola Giovanni, Geschwind Daniel H, Starkman Sidney, Miller Chad M, Kidwell Chelsea S, Liebeskind David S, Martin Neil A Genomic profiles of damage and protection in human intracerebral hemorrhage Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(11): 1860-75.
Ohab J J, Carmichael S T Poststroke neurogenesis: emerging principles of migration and localization of immature neurons The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2008; 14(4): 369-80.
Miller Chad M, Vespa Paul, Saver Jeffrey L, Kidwell Chelsea S, Carmichael Stanley T, Alger Jeffry, Frazee John, Starkman Sid, Liebeskind David, Nenov Valeriy, Elashoff Robert, Martin Neil Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage Surgical neurology, 2008; 69(5): 441-6; discussion 446.
Carmichael S Thomas Themes and strategies for studying the biology of stroke recovery in the poststroke epoch Stroke; a journal of cerebral circulation, 2008; 39(4): 1380-8.
Popa-Wagner Aurel, Carmichael Stanley Thomas, Kokaia Zaal, Kessler Christof, Walker Lary C The response of the aged brain to stroke: too much, too soon? Current neurovascular research, 2007; 4(3): 216-27.
Ohab John J, Fleming Sheila, Blesch Armin, Carmichael S Thomas A neurovascular niche for neurogenesis after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(50): 13007-16.
Li Songlin, Carmichael S Thomas Growth-associated gene and protein expression in the region of axonal sprouting in the aged brain after stroke Neurobiology of disease, 2006; 23(2): 362-73.
Carmichael S Thomas Cellular and molecular mechanisms of neural repair after stroke: making waves Annals of neurology, 2006; 59(5): 735-42.
Visnyei Koppany, Tatsukawa Keith J, Erickson Rebecca I, Simonian Sharis, Oknaian Nareg, Carmichael S Thomas, Kornblum Harley I Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion Experimental neurology, 2006; 197(2): 465-74.
Tsai Peter T, Ohab John J, Kertesz Nathalie, Groszer Matthias, Matter Cheryl, Gao Jing, Liu Xin, Wu Hong, Carmichael S Thomas A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(4): 1269-74.
Carmichael S Thomas Rodent models of focal stroke: size, mechanism, and purpose NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 2005; 2(3): 396-409.
Carmichael S Thomas, Archibeque Ivonne, Luke Linslee, Nolan Tim, Momiy Janneth, Li Songlin Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex Experimental neurology, 2005; 193(2): 291-311.
Li Songlin, Zheng Jian, Carmichael S Thomas Increased oxidative protein and DNA damage but decreased stress response in the aged brain following experimental stroke Neurobiology of disease, 2005; 18(3): 432-40.
Carmichael S Thomas, Tatsukawa Keith, Katsman Diana, Tsuyuguchi Naohiro, Kornblum Harley I Evolution of diaschisis in a focal stroke model Stroke; a journal of cerebral circulation, 2004; 35(3): 758-63.
Mir Halleh M, Tatsukawa Keith J, Carmichael S Thomas, Chesselet Marie-Francoise, Kornblum Harley I Metabolic correlates of lesion-specific plasticity: an in vivo imaging study Brain research, 2004; 1002(1-2): 28-34.
Carmichael S Thomas Gene expression changes after focal stroke, traumatic brain and spinal cord injuries Current opinion in neurology, 2003; 16(6): 699-704.
Katsman Diana, Zheng Jian, Spinelli Kateri, Carmichael S Thomas Tissue microenvironments within functional cortical subdivisions adjacent to focal stroke Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003; 23(9): 997-1009.
Carmichael S Thomas Plasticity of cortical projections after stroke The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2003; 9(1): 64-75.
Carmichael S Thomas, Chesselet Marie-FranÁoise Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002; 22(14): 6062-70.
Carmichael S Thomas New laboratory start-up in the 21st century Trends in neurosciences, 2002; 25(6): 287-8.
Carmichael S T, Wei L, Rovainen C M, Woolsey T A New patterns of intracortical projections after focal cortical stroke Neurobiology of disease, 2001; 8(5): 910-22.