Yi E. Sun, Ph.D.

Titles

Associate Professor, Psychiatry and Biobehavioral Sciences
Associate Professor In-Residence, Semel Institute for Neuroscience and Human Behavior
Molecular & Medical Pharmacology
Member, Brain Research Institute
Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
Gene Regulation GPB Home Area
JCCC Gene Regulation Program Area
Molecular Pharmacology GPB Home Area
Neuroscience GPB Home Area
Neuroscience IDP
Faculty, Molecular Biology IDP
Molecular, Cellular, and Integrative Physiology IDP

Contact Information

Email
ysun@mednet.ucla.edu
Phone
Lab Number: (310) 267-2197 310-267-2197Office Phone Number: 310-825-9506 310-825-9506Work Phone Number: 310-825-9506
Address
Laboratory Address: Laboratory635 Charles E. Young Drive SouthLos Angeles, CA 90095UNITED STATES Office Address: OfficeNRB 351, 635 Charles E. Young Drive SouthLos Angeles, CA 90095UNITED STATES

Publications:

Zeng Yan, Tan Miao, Kohyama Jun, Sneddon Marissa, Watson Joseph B, Sun Yi E, Xie Cui-Wei   Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(49): 17800-10.
Tao Jifang, Wu Hao, Lin Quan, Wei Weizheng, Lu Xiao-Hong, Cantle Jeffrey P, Ao Yan, Olsen Richard W, Yang X William, Mody Istvan, Sofroniew Michael V, Sun Yi E   Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(22): 8306-19.
Wilburn Brian, Rudnicki Dobrila D, Zhao Jing, Weitz Tara Murphy, Cheng Yin, Gu Xiaofeng, Greiner Erin, Park Chang Sin, Wang Nan, Sopher Bryce L, La Spada Albert R, Osmand Alex, Margolis Russell L, Sun Yi E, Yang X William   An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice Neuron, 2011; 70(3): 427-40.
Wu Hao, D'Alessio Ana C, Ito Shinsuke, Xia Kai, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi   Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells Nature, 2011; 473(7347): 389-93.
Wu Hao, D'Alessio Ana C, Ito Shinsuke, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi   Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells Genes & development, 2011; 25(7): 679-84.
Ge, W He, F Kim, KJ Blanchi, B Coskun, V Nguyen, L Wu, X Zhao, J Heng, JI Martinowich, K Tao, J Wu, H Castro, D Sobeih, MM Corfas, G Gleeson, JG Greenberg, ME Guillemot, F Sun, YE   Coupling of cell migration with neurogenesis by proneural bHLH factors PNAS, 2006; 103(5): 1319-1324.
Damelin, M Sun, YE Sodja, VB Bestor, TH   Decatenation checkpoint deficiency in stem and progenitor cells Cancer cell, 2005; 8(6): 479-84.
Ladi, E Nichols, JT Ge, W Miyamoto, A Yao, C Yang, LT Boulter, J Sun, YE Kintner, C Weinmaster, G   The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands The Journal of cell biology. , 2005; 170(6): 983-92.
Fan, G Martinowich, K Chin, MH He, F Fouse, SD Hutnick, L Hattori, D Ge, W Shen, Y Wu, H ten Hoeve, J Shuai, K Sun, YE   DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling Development (Cambridge, England) , 2005; 132(15): 3345-56.
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He, F Ge, W Martinowich, K Becker-Catania, S Coskun, V Zhu, W Wu, H Castro, D Guillemot, F Fan, G de Vellis, J Sun, YE   A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis Nature neuroscience. , 2005; 8(5): 616-25.
Martin, KC Sun, YE   To learn better, keep the HAT on Neuron. , 2004; 42(6): 879-81.
Martinowich, K Hattori, D Wu, H Fouse, S He, F Hu, Y Fan, G Sun, YE   DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation Science. , 2003; 302(5646): 890-3.
Sun, Y Nadal-Vicens, M Misono, S Lin, MZ Zubiaga, A Hua, X Fan, G Greenberg, ME   Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms Cell. , 2001; 104(3): 365-76.
Fan G, Egles C, Sun Y, Minichiello L, Renger J, Klein R, Liu G, Jaenisch R   NT4 and BDNF have Overlapping as well as Distinct Function in vivo, Nature Neuroscience, 2000; 3: 350-357.
Gao, Y Sun, Y Frank, KM Dikkes, P Fujiwara, Y Seidl, KJ Sekiguchi, JM Rathbun, GA Swat, W Wang, J Bronson, RT Malynn, BA Bryans, M Zhu, C Chaudhuri, J Davidson, L Ferrini, R Stamato, T Orkin, SH Greenberg, ME Alt, FW   A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis Cell. , 1998; 95(7): 891-902.
Bonni A*, Sun Y*(equal first authorship), Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME   Regulation of CNS Gliogenesis by JAK-STAT Signaling Pathway, Science, 1997; 278: 477-483.
Rao MS, Sun Y, Escary JL, Perreau J, Tresser S, Patterson PH, Zigmond RE, Brulet P, Landis SC   Leukemia Inhibitory Factor Mediates an Injury Response but not a target-directed developmental transmitter switch in sympathetic neurons, Neuron, 1993; 11: 1175-1185.