Cholinergic Receptor Signaling in the Hippocampal Network

Available immediately in the Neurobiology Laboratory, National Institute of Environmental Health Sciences (NIEHS/NIH), in Research Triangle Park, NC, to study the role of cholinergic receptor signaling and plasticity in the septo-hippocampal-entorhinal cortical circuit. Current projects in the lab utilize a variety of in vitro and in vivo techniques to asses neuronal and circuit function, including  (but not limited to) electrophysiology, opto- and chemico-genetics, confocal and two-photon imaging, in vivo fiber photometry, rabies-virus synaptic tracing, and a variety of neurobehavioral tests in the core at NIEHS. Area of research focus for the postdoctoral fellow is open, but should be broadly related to mechanisms or function of cholinergic signaling in the brain. Current research projects include studying how synaptic circuitry within the hippocampus and basal forebrain are functionally integrated, determining how cholinergic innervation within the hippocampus and entorhinal cortex regulates excitability and plasticity, examining the initiation and regulation of theta rhythms, and determining how cholinergic receptors regulate proliferation of neural stem cells within the hippocampus. Applicants must have less than 5 years of postdoctoral experience, and salaries start at an annual rate of $ 55,900 per year (for those with less than 1 year experience), with annual increases of $ 1,600 per year.

Interested candidates should:
Contact: Dr. Jerrel L. Yakel at Yakel@niehs.nih.gov or Phone Number: 984-387-3466

For additional information concerning the research projects and publications, visit the following website: