Nelson Freimer, M.D.

Biography

Dr. Nelson Freimer is Director of UCLA’s Depression Grand Challenge, a campuswide initiative that aims to cut the burden of depression in half by 2050. He is  Maggie G. Gilbert Endowed Chair, Distinguished Professor of Psychiatry and Human Genetics, and Director of the Center for Neurobehavioral Genetics. He also directs the UCLA Neuroscience Genomics Core, Dr. Freimer received an M.D. degree from the Ohio State University, and completed residency training in psychiatry (at UC San Francisco) and a postdoctoral fellowship in human genetics (at Columbia University). He joined the UCLA faculty in 2000 after 10 years on the faculty at UC San Francisco.

The research in Dr. Freimer’s laboratory aims to use large scale genomics methods to identify the genetic basis of complex traits, particularly neurobehavioral disorders including bipolar disorder, schizophrenia, depression, and Tourette Syndrome. He has also conducted large-scale genomics studies of metabolic phenotypes and cardiovascular disorders. His research group has pioneered in whole genome sequencing studies of such disorders as well as the application of large-scale genomics to our understanding of non-human primates. A current focus of his work is the exploration of digital approaches to phenotyping human behavior.

Nag Abhishek, Bochukova Elena G, Kremeyer Barbara, Campbell Desmond D, Muller Heike, Valencia-Duarte Ana V, Cardona Julio, Rivas Isabel C, Mesa Sandra C, Cuartas Mauricio, Garcia Jharley, Bedoya Gabriel, Cornejo William, Herrera Luis D, Romero Roxana, Fournier Eduardo, Reus Victor I, Lowe Thomas L, Farooqi I Sadaf, Farooqi I Sadaf, Mathews Carol A, McGrath Lauren M, Yu Dongmei, Cook Ed, Wang Kai, Scharf Jeremiah M, Pauls David L, Freimer Nelson B, Plagnol Vincent, Ruiz-Linares Andrés   CNV analysis in Tourette syndrome implicates large genomic rearrangements in COL8A1 and NRXN1 PloS one, 2013; 8(3): e59061.

Chen Kevin, Budman Cathy L, Diego Herrera Luis, Witkin Joanna E, Weiss Nicholas T, Lowe Thomas L, Freimer Nelson B, Reus Victor I, Mathews Carol A   Prevalence and clinical correlates of explosive outbursts in Tourette syndrome Psychiatry research, 2013; 205(3): 269-75.

Ma Dongzhu, Jasinska Anna, Kristoff Jan, Grobler J Paul, Turner Trudy, Jung Yoon, Schmitt Christopher, Raehtz Kevin, Feyertag Felix, Martinez Sosa Natalie, Wijewardana Viskam, Burke Donald S, Robertson David L, Tracy Russell, Pandrea Ivona, Freimer Nelson, Apetrei Cristian, Apetrei Cristian   SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations PLoS pathogens, 2013; 9(1): e1003011.

Cramer Jennifer Danzy, Gaetano Tegan, Gray Joseph P, Grobler Paul, Lorenz Joseph G, Freimer Nelson B, Schmitt Christopher A, Turner Trudy R   Variation in Scrotal Color Among Widely Distributed Vervet Monkey Populations (Chlorocebus Aethiops Pygerythrus and Chlorocebus Aethiops Sabaeus) American journal of primatology, 2013; .

Jasinska Anna J, Lin Michelle K, Service Susan, Choi Oi-Wa, Deyoung Joseph, Grujic Olivera, Kong Sit-Yee, Jung Yoon, Jorgensen Mathew J, Fairbanks Lynn A, Turner Trudy, Cantor Rita M, Wasserscheid Jessica, Dewar Ken, Warren Wesley, Wilson Richard K, Weinstock George, Jentsch J David, Freimer Nelson B   A non-human primate system for large-scale genetic studies of complex traits Human molecular genetics, 2012; 15(6): .

Congdon Eliza, Service Susan, Wessman Jaana, Seppänen Jouni K, Schönauer Stefan, Miettunen Jouko, Turunen Hannu, Koiranen Markku, Joukamaa Matti, Järvelin Marjo-Riitta, Peltonen Leena, Veijola Juha, Mannila Heikki, Paunio Tiina, Freimer Nelson B   Early environment and neurobehavioral development predict adult temperament clusters PloS one, 2012; 7(7): e38065.

McQuillan Ruth, Eklund Niina, Pirastu Nicola, Kuningas Maris, McEvoy Brian P, Esko Tõnu, Corre Tanguy, Davies Gail, Kaakinen Marika, Lyytikäinen Leo-Pekka, Kristiansson Kati, Havulinna Aki S, Gögele Martin, Vitart Veronique, Tenesa Albert, Aulchenko Yurii, Hayward Caroline, Johansson Asa, Boban Mladen, Ulivi Sheila, Robino Antonietta, Boraska Vesna, Igl Wilmar, Wild Sarah H, Zgaga Lina, Amin Najaf, Theodoratou Evropi, PolaÅ¡ek Ozren, Girotto Giorgia, Lopez Lorna M, Sala Cinzia, Lahti Jari, Laatikainen Tiina, Prokopenko Inga, Kals Mart, Viikari Jorma, Yang Jian, Pouta Anneli, Estrada Karol, Hofman Albert, Freimer Nelson, Martin Nicholas G, Kähönen Mika, Milani Lili, Heliövaara Markku, Vartiainen Erkki, Räikkönen Katri, Masciullo Corrado, Starr John M, Hicks Andrew A, Esposito Laura, Kolčić Ivana, Farrington Susan M, Oostra Ben, Zemunik Tatijana, Campbell Harry, Kirin Mirna, Pehlic Marina, Faletra Flavio, Porteous David, Pistis Giorgio, Widén Elisabeth, Salomaa Veikko, Koskinen Seppo, Fischer Krista, Lehtimäki Terho, Heath Andrew, McCarthy Mark I, Rivadeneira Fernando, Montgomery Grant W, Tiemeier Henning, Hartikainen Anna-Liisa, Madden Pamela A F, d’Adamo Pio, Hastie Nicholas D, Gyllensten Ulf, Wright Alan F, van Duijn Cornelia M, Dunlop Malcolm, Rudan Igor, Gasparini Paolo, Pramstaller Peter P, Deary Ian J, Toniolo Daniela, Eriksson Johan G, Jula Antti, Raitakari Olli T, Metspalu Andres, Perola Markus, Järvelin Marjo-Riitta, Uitterlinden André, Visscher Peter M, Wilson James F, Wilson James F   Evidence of inbreeding depression on human height PLoS genetics, 2012; 8(7): e1002655.

Kettunen Johannes, Tukiainen Taru, Sarin Antti-Pekka, Ortega-Alonso Alfredo, Tikkanen Emmi, Lyytikäinen Leo-Pekka, Kangas Antti J, Soininen Pasi, Würtz Peter, Silander Kaisa, Dick Danielle M, Rose Richard J, Savolainen Markku J, Viikari Jorma, Kähönen Mika, Lehtimäki Terho, Pietiläinen Kirsi H, Inouye Michael, McCarthy Mark I, Jula Antti, Eriksson Johan, Raitakari Olli T, Salomaa Veikko, Kaprio Jaakko, Järvelin Marjo-Riitta, Peltonen Leena, Perola Markus, Freimer Nelson B, Ala-Korpela Mika, Palotie Aarno, Ripatti Samuli   Genome-wide association study identifies multiple loci influencing human serum metabolite levels Nature genetics, 2012; 44(3): 269-76.

Levine Andrew J, Service Susan, Miller Eric N, Reynolds Sandra M, Singer Elyse J, Shapshak Paul, Martin Eileen M, Sacktor Ned, Becker James T, Jacobson Lisa P, Thompson Paul, Freimer Nelson   Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2012; 15(6): .

Stein Jason L, Medland Sarah E, Vasquez Alejandro Arias, Hibar Derrek P, Senstad Rudy E, Winkler Anderson M, Toro Roberto, Appel Katja, Bartecek Richard, Bergmann Ørjan, Bernard Manon, Brown Andrew A, Cannon Dara M, Chakravarty M Mallar, Christoforou Andrea, Domin Martin, Grimm Oliver, Hollinshead Marisa, Holmes Avram J, Homuth Georg, Hottenga Jouke-Jan, Langan Camilla, Lopez Lorna M, Hansell Narelle K, Hwang Kristy S, Kim Sungeun, Laje Gonzalo, Lee Phil H, Liu Xinmin, Loth Eva, Lourdusamy Anbarasu, Mattingsdal Morten, Mohnke Sebastian, Maniega Susana Muñoz, Nho Kwangsik, Nugent Allison C, O’Brien Carol, Papmeyer Martina, Pütz Benno, Ramasamy Adaikalavan, Rasmussen Jerod, Rijpkema Mark, Risacher Shannon L, Roddey J Cooper, Rose Emma J, Ryten Mina, Shen Li, Sprooten Emma, Strengman Eric, Teumer Alexander, Trabzuni Daniah, Turner Jessica, van Eijk Kristel, van Erp Theo G M, van Tol Marie-Jose, Wittfeld Katharina, Wolf Christiane, Woudstra Saskia, Aleman Andre, Alhusaini Saud, Almasy Laura, Binder Elisabeth B, Brohawn David G, Cantor Rita M, Carless Melanie A, Corvin Aiden, Czisch Michael, Curran Joanne E, Davies Gail, de Almeida Marcio A A, Delanty Norman, Depondt Chantal, Duggirala Ravi, Dyer Thomas D, Erk Susanne, Fagerness Jesen, Fox Peter T, Freimer Nelson B, Gill Michael, Göring Harald H H, Hagler Donald J, Hoehn David, Holsboer Florian, Hoogman Martine, Hosten Norbert, Jahanshad Neda, Johnson Matthew P, Kasperaviciute Dalia, Kent Jack W, Kochunov Peter, Lancaster Jack L, Lawrie Stephen M, Liewald David C, Mandl René, Matarin Mar, Mattheisen Manuel, Meisenzahl Eva, Melle Ingrid, Moses Eric K, Mühleisen Thomas W, Nauck Matthias, Nöthen Markus M, Olvera Rene L, Pandolfo Massimo, Pike G Bruce, Puls Ralf, Reinvang Ivar, Rentería Miguel E, Rietschel Marcella, Roffman Joshua L, Royle Natalie A, Rujescu Dan, Savitz Jonathan, Schnack Hugo G, Schnell Knut, Seiferth Nina, Smith Colin, Steen Vidar M, Valdés Hernández Maria C, Van den Heuvel Martijn, van der Wee Nic J, Van Haren Neeltje E M, Veltman Joris A, Völzke Henry, Walker Robert, Westlye Lars T, Whelan Christopher D, Agartz Ingrid, Boomsma Dorret I, Cavalleri Gianpiero L, Dale Anders M, Djurovic Srdjan, Drevets Wayne C, Hagoort Peter, Hall Jeremy, Heinz Andreas, Jack Clifford R, Foroud Tatiana M, Le Hellard Stephanie, Macciardi Fabio, Montgomery Grant W, Poline Jean Baptiste, Porteous David J, Sisodiya Sanjay M, Starr John M, Sussmann Jessika, Toga Arthur W, Veltman Dick J, Walter Henrik, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Bis Joshua C, Ikram M Arfan, Smith Albert V, Gudnason Vilmundur, Tzourio Christophe, Vernooij Meike W, Launer Lenore J, DeCarli Charles, Seshadri Sudha, Seshadri Sudha, Andreassen Ole A, Apostolova Liana G, Bastin Mark E, Blangero John, Brunner Han G, Buckner Randy L, Cichon Sven, Coppola Giovanni, de Zubicaray Greig I, Deary Ian J, Donohoe Gary, de Geus Eco J C, Espeseth Thomas, Fernández Guillén, Glahn David C, Grabe Hans J, Hardy John, Hulshoff Pol Hilleke E, Jenkinson Mark, Kahn René S, McDonald Colm, McIntosh Andrew M, McMahon Francis J, McMahon Katie L, Meyer-Lindenberg Andreas, Morris Derek W, Müller-Myhsok Bertram, Nichols Thomas E, Ophoff Roel A, Paus Tomas, Pausova Zdenka, Penninx Brenda W, Potkin Steven G, Sämann Philipp G, Saykin Andrew J, Schumann Gunter, Smoller Jordan W, Wardlaw Joanna M, Weale Michael E, Martin Nicholas G, Franke Barbara, Wright Margaret J, Thompson Paul M, Thompson Paul M   Identification of common variants associated with human hippocampal and intracranial volumes Nature genetics, 2012; 44(5): 552-61.

Miettunen Jouko, Isohanni Matti, Paunio Tiina, Freimer Nelson, Taanila Anja, Ekelund Jesper, Järvelin Marjo-Riitta, Joukamaa Matti, Lichtermann Dirk, Koivumaa-Honkanen Heli, Veijola Juha   Predicting depression with psychopathology and temperament traits: the northern Finland 1966 birth cohort Depression research and treatment, 2012; 2012(7411): 160905.

Reich David, Patterson Nick, Campbell Desmond, Tandon Arti, Mazieres Stéphane, Ray Nicolas, Parra Maria V, Rojas Winston, Duque Constanza, Mesa Natalia, García Luis F, Triana Omar, Blair Silvia, Maestre Amanda, Dib Juan C, Bravi Claudio M, Bailliet Graciela, Corach Daniel, Hünemeier Tábita, Bortolini Maria Cátira, Salzano Francisco M, Petzl-Erler María Luiza, Acuña-Alonzo Victor, Aguilar-Salinas Carlos, Canizales-Quinteros Samuel, Tusié-Luna Teresa, Riba Laura, Rodríguez-Cruz Maricela, Lopez-Alarcón Mardia, Coral-Vazquez Ramón, Canto-Cetina Thelma, Silva-Zolezzi Irma, Fernandez-Lopez Juan Carlos, Contreras Alejandra V, Jimenez-Sanchez Gerardo, Gómez-Vázquez Maria José, Molina Julio, Carracedo Angel, Salas Antonio, Gallo Carla, Poletti Giovanni, Witonsky David B, Alkorta-Aranburu Gorka, Sukernik Rem I, Osipova Ludmila, Fedorova Sardana A, Vasquez René, Villena Mercedes, Moreau Claudia, Barrantes Ramiro, Pauls David, Excoffier Laurent, Bedoya Gabriel, Rothhammer Francisco, Dugoujon Jean-Michel, Larrouy Georges, Klitz William, Labuda Damian, Kidd Judith, Kidd Kenneth, Di Rienzo Anna, Freimer Nelson B, Price Alkes L, Ruiz-Linares Andrés   Reconstructing Native American population history Nature, 2012; 488(7411): 370-4.

Wessman Jaana, Schönauer Stefan, Miettunen Jouko, Turunen Hannu, Parviainen Pekka, Seppänen Jouni K, Congdon Eliza, Service Susan, Koiranen Markku, Ekelund Jesper, Laitinen Jaana, Taanila Anja, Tammelin Tuija, Hintsanen Mirka, Pulkki-RÃ¥back Laura, Keltikangas-Järvinen Liisa, Viikari Jorma, Raitakari Olli T, Joukamaa Matti, Järvelin Marjo-Riitta, Freimer Nelson, Peltonen Leena, Veijola Juha, Mannila Heikki, Paunio Tiina   Temperament clusters in a normal population: implications for health and disease PloS one, 2012; 7(7): e33088.

Karayiorgou Maria, Flint Jonathan, Gogos Joseph A, Malenka Robert C, Malenka Robert C, Bargmann Cornelia I, Boyden Edward S, Bullmore Edward T, Chan Anthony W, Davis Michael, Deisseroth Karl, Dolmetch Ricardo E, Eggan Kevin, Fears Scott C, Freimer Nelson B, Geschwind Daniel H, Gordon Joshua, Nickerson Debbie A, Vanderhaeghen Pierre, Axel Richard, Zuker Charles S, Fischbach Gerald D   The best of times, the worst of times for psychiatric disease Nature neuroscience, 2012; 15(6): 811-812.

Surakka Ida, Isaacs Aaron, Karssen Lennart C, Laurila Pirkka-Pekka P, Middelberg Rita P S, Tikkanen Emmi, Ried Janina S, Lamina Claudia, Mangino Massimo, Igl Wilmar, Hottenga Jouke-Jan, Lagou Vasiliki, van der Harst Pim, Mateo Leach Irene, Esko Tõnu, Kutalik Zoltán, Wainwright Nicholas W, Struchalin Maksim V, Sarin Antti-Pekka, Kangas Antti J, Viikari Jorma S, Perola Markus, Rantanen Taina, Petersen Ann-Kristin, Soininen Pasi, Johansson Asa, Soranzo Nicole, Heath Andrew C, Papamarkou Theodore, Prokopenko Inga, Tönjes Anke, Kronenberg Florian, Döring Angela, Rivadeneira Fernando, Montgomery Grant W, Whitfield John B, Kähönen Mika, Lehtimäki Terho, Freimer Nelson B, Willemsen Gonneke, de Geus Eco J C, Palotie Aarno, Sandhu Manj S, Waterworth Dawn M, Metspalu Andres, Stumvoll Michael, Uitterlinden André G, Jula Antti, Navis Gerjan, Wijmenga Cisca, Wolffenbuttel Bruce H R, Taskinen Marja-Riitta, Ala-Korpela Mika, Kaprio Jaakko, Kyvik Kirsten O, Boomsma Dorret I, Pedersen Nancy L, Gyllensten Ulf, Wilson James F, Rudan Igor, Campbell Harry, Pramstaller Peter P, Spector Tim D, Witteman Jacqueline C M, Eriksson Johan G, Salomaa Veikko, Oostra Ben A, Raitakari Olli T, Wichmann H-Erich, Gieger Christian, Järvelin Marjo-Riitta, Martin Nicholas G, Hofman Albert, McCarthy Mark I, Peltonen Leena, van Duijn Cornelia M, Aulchenko Yurii S, Ripatti Samuli, Ripatti Samuli   A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol PLoS genetics, 2011; 7(10): e1002333.

Woods Roger P, Fears Scott C, Jorgensen Matthew J, Fairbanks Lynn A, Toga Arthur W, Freimer Nelson B   A web-based brain atlas of the vervet monkey, Chlorocebus aethiops NeuroImage, 2011; 54(3): 1872-80.

Fears Scott C, Scheibel Kevin, Abaryan Zvart, Lee Chris, Service Susan K, Jorgensen Matthew J, Fairbanks Lynn A, Cantor Rita M, Freimer Nelson B, Woods Roger P   Anatomic brain asymmetry in vervet monkeys PloS one, 2011; 6(12): e28243.

Schumann Gunter, Coin Lachlan J, Lourdusamy Anbarasu, Charoen Pimphen, Berger Karen H, Stacey David, Desrivières Sylvane, Aliev Fazil A, Khan Anokhi A, Amin Najaf, Aulchenko Yurii S, Bakalkin Georgy, Bakker Stephan J, Balkau Beverley, Beulens Joline W, Bilbao Ainhoa, de Boer Rudolf A, Beury Delphine, Bots Michiel L, Breetvelt Elemi J, Cauchi Stéphane, Cavalcanti-Proença Christine, Chambers John C, Clarke Toni-Kim, Dahmen Norbert, de Geus Eco J, Dick Danielle, Ducci Francesca, Easton Alanna, Edenberg Howard J, Esko Tõnu, Esk Tõnu, Fernández-Medarde Alberto, Foroud Tatiana, Freimer Nelson B, Girault Jean-Antoine, Grobbee Diederick E, Guarrera Simonetta, Gudbjartsson Daniel F, Hartikainen Anna-Liisa, Heath Andrew C, Hesselbrock Victor, Hofman Albert, Hottenga Jouke-Jan, Isohanni Matti K, Kaprio Jaakko, Khaw Kay-Tee, Kuehnel Brigitte, Laitinen Jaana, Lobbens Stéphane, Luan Jian’an, Mangino Massimo, Maroteaux Matthieu, Matullo Giuseppe, McCarthy Mark I, Mueller Christian, Navis Gerjan, Numans Mattijs E, Núñez Alejandro, Nyholt Dale R, Onland-Moret Charlotte N, Oostra Ben A, O’Reilly Paul F, Palkovits Miklos, Penninx Brenda W, Polidoro Silvia, Pouta Anneli, Prokopenko Inga, Ricceri Fulvio, Santos Eugenio, Smit Johannes H, Soranzo Nicole, Song Kijoung, Sovio Ulla, Stumvoll Michael, Surakk Ida, Thorgeirsson Thorgeir E, Thorsteinsdottir Unnur, Troakes Claire, Tyrfingsson Thorarinn, Tönjes Anke, Uiterwaal Cuno S, Uitterlinden Andre G, van der Harst Pim, van der Schouw Yvonne T, Staehlin Oliver, Vogelzangs Nicole, Vollenweider Peter, Waeber Gerard, Wareham Nicholas J, Waterworth Dawn M, Whitfield John B, Wichmann Erich H, Willemsen Gonneke, Witteman Jacqueline C, Yuan Xin, Zhai Guangju, Zhao Jing H, Zhang Weihua, Martin Nicholas G, Metspalu Andres, Doering Angela, Scott James, Spector Tim D, Loos Ruth J, Boomsma Dorret I, Mooser Vincent, Peltonen Leena, Stefansson Kari, van Duijn Cornelia M, Vineis Paolo, Sommer Wolfgang H, Kooner Jaspal S, Spanagel Rainer, Heberlein Ulrike A, Jarvelin Marjo-Riitta, Elliott Paul   Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption Proceedings of the National Academy of Sciences of the United States of America, 2011; 108(17): 7119-24.

Ripke Stephan, Sanders Alan R, Kendler Kenneth S, Levinson Douglas F, Sklar Pamela, Holmans Peter A, Lin Dan-Yu, Duan Jubao, Ophoff Roel A, Andreassen Ole A, Scolnick Edward, Cichon Sven, St Clair David, Corvin Aiden, Gurling Hugh, Werge Thomas, Rujescu Dan, Blackwood Douglas H R, Pato Carlos N, Malhotra Anil K, Purcell Shaun, Dudbridge Frank, Neale Benjamin M, Rossin Lizzy, Visscher Peter M, Posthuma Danielle, Ruderfer Douglas M, Fanous Ayman, Stefansson Hreinn, Steinberg Stacy, Mowry Bryan J, Golimbet Vera, De Hert Marc, Jönsson Erik G, Bitter István, Pietiläinen Olli P H, Collier David A, Tosato Sarah, Agartz Ingrid, Albus Margot, Alexander Madeline, Amdur Richard L, Amin Farooq, Bass Nicholas, Bergen Sarah E, Black Donald W, Børglum Anders D, Brown Matthew A, Bruggeman Richard, Buccola Nancy G, Byerley William F, Cahn Wiepke, Cantor Rita M, Carr Vaughan J, Catts Stanley V, Choudhury Khalid, Cloninger C Robert, Cormican Paul, Craddock Nicholas, Danoy Patrick A, Datta Susmita, de Haan Lieuwe, Demontis Ditte, Dikeos Dimitris, Djurovic Srdjan, Donnelly Peter, Donohoe Gary, Duong Linh, Dwyer Sarah, Fink-Jensen Anders, Freedman Robert, Freimer Nelson B, Friedl Marion, Georgieva Lyudmila, Giegling Ina, Gill Michael, Glenthøj Birte, Godard Stephanie, Hamshere Marian, Hansen Mark, Hansen Thomas, Hartmann Annette M, Henskens Frans A, Hougaard David M, Hultman Christina M, Ingason Andrés, Jablensky Assen V, Jakobsen Klaus D, Jay Maurice, Jürgens Gesche, Kahn René S, Keller Matthew C, Kenis Gunter, Kenny Elaine, Kim Yunjung, Kirov George K, Konnerth Heike, Konte Bettina, Krabbendam Lydia, Krasucki Robert, Lasseter Virginia K, Laurent Claudine, Lawrence Jacob, Lencz Todd, Lerer F Bernard, Liang Kung-Yee, Lichtenstein Paul, Lieberman Jeffrey A, Linszen Don H, Lönnqvist Jouko, Loughland Carmel M, Maclean Alan W, Maher Brion S, Maier Wolfgang, Mallet Jacques, Malloy Pat, Mattheisen Manuel, Mattingsdal Morten, McGhee Kevin A, McGrath John J, McIntosh Andrew, McLean Duncan E, McQuillin Andrew, Melle Ingrid, Michie Patricia T, Milanova Vihra, Morris Derek W, Mors Ole, Mortensen Preben B, Moskvina Valentina, Muglia Pierandrea, Myin-Germeys Inez, Nertney Deborah A, Nestadt Gerald, Nielsen Jimmi, Nikolov Ivan, Nordentoft Merete, Norton Nadine, Nöthen Markus M, O’Dushlaine Colm T, Olincy Ann, Olsen Line, O’Neill F Anthony, Orntoft Torben F, Owen Michael J, Pantelis Christos, Papadimitriou George, Pato Michele T, Peltonen Leena, Petursson Hannes, Pickard Ben, Pimm Jonathan, Pulver Ann E, Puri Vinay, Quested Digby, Quinn Emma M, Rasmussen Henrik B, Réthelyi János M, Ribble Robert, Rietschel Marcella, Riley Brien P, Ruggeri Mirella, Schall Ulrich, Schulze Thomas G, Schwab Sibylle G, Scott Rodney J, Shi Jianxin, Sigurdsson Engilbert, Silverman Jeremy M, Spencer Chris C A, Stefansson Kari, Strange Amy, Strengman Eric, Stroup T Scott, Suvisaari Jaana, Terenius Lars, Thirumalai Srinivasa, Thygesen Johan H, Timm Sally, Toncheva Draga, van den Oord Edwin, van Os Jim, van Winkel Ruud, Veldink Jan, Walsh Dermot, Wang August G, Wiersma Durk, Wildenauer Dieter B, Williams Hywel J, Williams Nigel M, Wormley Brandon, Zammit Stan, Sullivan Patrick F, O’Donovan Michael C, Daly Mark J, Gejman Pablo V, Gejman Pablo V   Genome-wide association study identifies five new schizophrenia loci Nature genetics, 2011; 43(10): 969-76.

Desrivières Sylvane, Lourdusamy Anbarasu, Müller Christian, Ducci Francesca, Wong Cybele P, Kaakinen Marika, Pouta Anneli, Hartikainen Anna-Liisa, Isohanni Matti, Charoen Pimphen, Peltonen Leena, Freimer Nelson, Elliott Paul, Jarvelin Marjo-Riitta, Schumann Gunter   Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents Addiction biology, 2011; 16(3): 510-3.

Miettunen Jouko, Veijola Juha, Isohanni Matti, Paunio Tiina, Freimer Nelson, Jääskeläinen Erika, Taanila Anja, Ekelund Jesper, Järvelin Marjo-Riitta, Peltonen Leena, Joukamaa Matti, Lichtermann Dirk   Identifying schizophrenia and other psychoses with psychological scales in the general population The Journal of nervous and mental disease, 2011; 199(4): 230-8.

Nyman Emma, Miettunen Jouko, Freimer Nelson, Joukamaa Matti, Mäki Pirjo, Ekelund Jesper, Peltonen Leena, Järvelin Marjo-Riitta, Veijola Juha, Paunio Tiina   Impact of temperament on depression and anxiety symptoms and depressive disorder in a population-based birth cohort Journal of affective disorders, 2011; 131(1-3): 393-7.

Nyman Emma S, Sulkava Sonja, Soronen Pia, Miettunen Jouko, Loukola Anu, Leppä Virpi, Joukamaa Matti, Mäki Pirjo, Järvelin Marjo-Riitta, Freimer Nelson, Peltonen Leena, Veijola Juha, Paunio Tiina   Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort BMJ open, 2011; 1(1): e000087.

Dehghan Abbas, Dupuis Josée, Barbalic Maja, Bis Joshua C, Eiriksdottir Gudny, Lu Chen, Pellikka Niina, Wallaschofski Henri, Kettunen Johannes, Henneman Peter, Baumert Jens, Strachan David P, Fuchsberger Christian, Vitart Veronique, Wilson James F, Paré Guillaume, Naitza Silvia, Rudock Megan E, Surakka Ida, de Geus Eco J C, Alizadeh Behrooz Z, Guralnik Jack, Shuldiner Alan, Tanaka Toshiko, Zee Robert Y L, Schnabel Renate B, Nambi Vijay, Kavousi Maryam, Ripatti Samuli, Nauck Matthias, Smith Nicholas L, Smith Albert V, Sundvall Jouko, Scheet Paul, Liu Yongmei, Ruokonen Aimo, Rose Lynda M, Larson Martin G, Hoogeveen Ron C, Freimer Nelson B, Teumer Alexander, Tracy Russell P, Launer Lenore J, Buring Julie E, Yamamoto Jennifer F, Folsom Aaron R, Sijbrands Eric J G, Pankow James, Elliott Paul, Keaney John F, Sun Wei, Sarin Antti-Pekka, Fontes João D, Badola Sunita, Astor Brad C, Hofman Albert, Pouta Anneli, Werdan Karl, Greiser Karin H, Kuss Oliver, Meyer zu Schwabedissen Henriette E, Thiery Joachim, Jamshidi Yalda, Nolte Ilja M, Soranzo Nicole, Spector Timothy D, Völzke Henry, Parker Alexander N, Aspelund Thor, Bates David, Young Lauren, Tsui Kim, Siscovick David S, Guo Xiuqing, Rotter Jerome I, Uda Manuela, Schlessinger David, Rudan Igor, Hicks Andrew A, Penninx Brenda W, Thorand Barbara, Gieger Christian, Coresh Joe, Willemsen Gonneke, Harris Tamara B, Uitterlinden Andre G, Järvelin Marjo-Riitta, Rice Kenneth, Radke Dörte, Salomaa Veikko, Willems van Dijk Ko, Boerwinkle Eric, Vasan Ramachandran S, Ferrucci Luigi, Gibson Quince D, Bandinelli Stefania, Snieder Harold, Boomsma Dorret I, Xiao Xiangjun, Campbell Harry, Hayward Caroline, Pramstaller Peter P, van Duijn Cornelia M, Peltonen Leena, Psaty Bruce M, Gudnason Vilmundur, Ridker Paul M, Homuth Georg, Koenig Wolfgang, Ballantyne Christie M, Witteman Jacqueline C M, Benjamin Emelia J, Perola Markus, Chasman Daniel I   Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels Circulation, 2011; 123(7): 731-8.

Pietiläinen Olli P H, Rehnström Karola, Jakkula Eveliina, Service Susan K, Congdon Eliza, Tilgmann Carola, Hartikainen Anna-Liisa, Taanila Anja, Heikura Ulla, Paunio Tiina, Ripatti Samuli, Jarvelin Marjo-Riitta, Isohanni Matti, Sabatti Chiara, Palotie Aarno, Freimer Nelson B, Peltonen Leena   Phenotype mining in CNV carriers from a population cohort Human molecular genetics, 2011; 20(13): 2686-95.

Wegmann Daniel, Kessner Darren E, Veeramah Krishna R, Mathias Rasika A, Nicolae Dan L, Yanek Lisa R, Sun Yan V, Torgerson Dara G, Rafaels Nicholas, Mosley Thomas, Becker Lewis C, Ruczinski Ingo, Beaty Terri H, Kardia Sharon L R, Meyers Deborah A, Barnes Kathleen C, Becker Diane M, Freimer Nelson B, Novembre John   Recombination rates in admixed individuals identified by ancestry-based inference Nature genetics, 2011; 43(9): 847-53.

Ducci Francesca, Kaakinen Marika, Pouta Anneli, Hartikainen Anna-Liisa, Veijola Juha, Isohanni Matti, Charoen Pimphen, Coin Lachlan, Hoggart Clive, Ekelund Jesper, Peltonen Leena, Freimer Nelson, Elliott Paul, Schumann Gunter, Järvelin Marjo-Riitta   TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood Biological psychiatry, 2011; 69(7): 650-60.

Teslovich Tanya M, Musunuru Kiran, Smith Albert V, Edmondson Andrew C, Stylianou Ioannis M, Koseki Masahiro, Pirruccello James P, Ripatti Samuli, Chasman Daniel I, Willer Cristen J, Johansen Christopher T, Fouchier Sigrid W, Isaacs Aaron, Peloso Gina M, Barbalic Maja, Ricketts Sally L, Bis Joshua C, Aulchenko Yurii S, Thorleifsson Gudmar, Feitosa Mary F, Chambers John, Orho-Melander Marju, Melander Olle, Johnson Toby, Li Xiaohui, Guo Xiuqing, Li Mingyao, Shin Cho Yoon, Jin Go Min, Jin Kim Young, Lee Jong-Young, Park Taesung, Kim Kyunga, Sim Xueling, Twee-Hee Ong Rick, Croteau-Chonka Damien C, Lange Leslie A, Smith Joshua D, Song Kijoung, Hua Zhao Jing, Yuan Xin, Luan Jian’an, Lamina Claudia, Ziegler Andreas, Zhang Weihua, Zee Robert Y L, Wright Alan F, Witteman Jacqueline C M, Wilson James F, Willemsen Gonneke, Wichmann H-Erich, Whitfield John B, Waterworth Dawn M, Wareham Nicholas J, Waeber Gérard, Vollenweider Peter, Voight Benjamin F, Vitart Veronique, Uitterlinden Andre G, Uda Manuela, Tuomilehto Jaakko, Thompson John R, Tanaka Toshiko, Surakka Ida, Stringham Heather M, Spector Tim D, Soranzo Nicole, Smit Johannes H, Sinisalo Juha, Silander Kaisa, Sijbrands Eric J G, Scuteri Angelo, Scott James, Schlessinger David, Sanna Serena, Salomaa Veikko, Saharinen Juha, Sabatti Chiara, Ruokonen Aimo, Rudan Igor, Rose Lynda M, Roberts Robert, Rieder Mark, Psaty Bruce M, Pramstaller Peter P, Pichler Irene, Perola Markus, Penninx Brenda W J H, Pedersen Nancy L, Pattaro Cristian, Parker Alex N, Pare Guillaume, Oostra Ben A, O’Donnell Christopher J, Nieminen Markku S, Nickerson Deborah A, Montgomery Grant W, Meitinger Thomas, McPherson Ruth, McCarthy Mark I, McArdle Wendy, Masson David, Martin Nicholas G, Marroni Fabio, Mangino Massimo, Magnusson Patrik K E, Lucas Gavin, Luben Robert, Loos Ruth J F, Lokki Marja-Liisa, Lettre Guillaume, Langenberg Claudia, Launer Lenore J, Lakatta Edward G, Laaksonen Reijo, Kyvik Kirsten O, Kronenberg Florian, König Inke R, Khaw Kay-Tee, Kaprio Jaakko, Kaplan Lee M, Johansson Asa, Jarvelin Marjo-Riitta, Janssens A Cecile J W, Ingelsson Erik, Igl Wilmar, Kees Hovingh G, Hottenga Jouke-Jan, Hofman Albert, Hicks Andrew A, Hengstenberg Christian, Heid Iris M, Hayward Caroline, Havulinna Aki S, Hastie Nicholas D, Harris Tamara B, Haritunians Talin, Hall Alistair S, Gyllensten Ulf, Guiducci Candace, Groop Leif C, Gonzalez Elena, Gieger Christian, Freimer Nelson B, Ferrucci Luigi, Erdmann Jeanette, Elliott Paul, Ejebe Kenechi G, Döring Angela, Dominiczak Anna F, Demissie Serkalem, Deloukas Panagiotis, de Geus Eco J C, de Faire Ulf, Crawford Gabriel, Collins Francis S, Chen Yii-der I, Caulfield Mark J, Campbell Harry, Burtt Noel P, Bonnycastle Lori L, Boomsma Dorret I, Boekholdt S Matthijs, Bergman Richard N, Barroso Inês, Bandinelli Stefania, Ballantyne Christie M, Assimes Themistocles L, Quertermous Thomas, Altshuler David, Seielstad Mark, Wong Tien Y, Tai E-Shyong, Feranil Alan B, Kuzawa Christopher W, Adair Linda S, Taylor Herman A, Borecki Ingrid B, Gabriel Stacey B, Wilson James G, Holm Hilma, Thorsteinsdottir Unnur, Gudnason Vilmundur, Krauss Ronald M, Mohlke Karen L, Ordovas Jose M, Munroe Patricia B, Kooner Jaspal S, Tall Alan R, Hegele Robert A, Kastelein John J P, Schadt Eric E, Rotter Jerome I, Boerwinkle Eric, Strachan David P, Mooser Vincent, Stefansson Kari, Reilly Muredach P, Samani Nilesh J, Schunkert Heribert, Cupples L Adrienne, Sandhu Manjinder S, Ridker Paul M, Rader Daniel J, van Duijn Cornelia M, Peltonen Leena, Abecasis Gonçalo R, Boehnke Michael, Kathiresan Sekar   Biological, clinical and population relevance of 95 loci for blood lipids Nature, 2010; 466(7307): 707-13.

Miettunen Jouko, Veijola Juha, Freimer Nelson, Lichtermann Dirk, Peltonen Leena, Paunio Tiina, Isohanni Matti, Joukamaa Matti, Ekelund Jesper   Data on schizotypy and affective scales are gender and education dependent–study in the Northern Finland 1966 Birth Cohort Psychiatry research, 2010; 178(2): 408-13.

Pawlikowska Ludmila, Strautnieks Sandra, Jankowska Irena, Czubkowski Piotr, Emerick Karan, Antoniou Anthony, Wanty Catherine, Fischler Bjorn, Jacquemin Emmanuel, Wali Sami, Blanchard Samra, Nielsen Inge-Merete, Bourke Billy, McQuaid Shirley, Lacaille Florence, Byrne Jane A, van Eerde Albertien M, Kolho Kaija-Leena, Klomp Leo, Houwen Roderick, Bacchetti Peter, Lobritto Steven, Hupertz Vera, McClean Patricia, Mieli-Vergani Giorgina, Shneider Benjamin, Nemeth Antal, Sokal Etienne, Freimer Nelson B, Knisely A S, Rosenthal Philip, Whitington Peter F, Pawlowska Joanna, Thompson Richard J, Bull Laura N   Differences in presentation and progression between severe FIC1 and BSEP deficiencies Journal of hepatology, 2010; 53(1): 170-8.

Widén Elisabeth, Ripatti Samuli, Cousminer Diana L, Surakka Ida, Lappalainen Tuuli, Järvelin Marjo-Riitta, Eriksson Johan G, Raitakari Olli, Salomaa Veikko, Sovio Ulla, Hartikainen Anna-Liisa, Pouta Anneli, McCarthy Mark I, Osmond Clive, Kajantie Eero, Lehtimäki Terho, Viikari Jorma, Kähönen Mika, Tyler-Smith Chris, Freimer Nelson, Hirschhorn Joel N, Peltonen Leena, Palotie Aarno   Distinct variants at LIN28B influence growth in height from birth to adulthood American journal of human genetics, 2010; 86(5): 773-82.

Pillas Demetris, Hoggart Clive J, Evans David M, O’Reilly Paul F, Sipilä Kirsi, Lähdesmäki Raija, Millwood Iona Y, Kaakinen Marika, Netuveli Gopalakrishnan, Blane David, Charoen Pimphen, Sovio Ulla, Pouta Anneli, Freimer Nelson, Hartikainen Anna-Liisa, Laitinen Jaana, Vaara Sarianna, Glaser Beate, Crawford Peter, Timpson Nicholas J, Ring Susan M, Deng Guohong, Zhang Weihua, McCarthy Mark I, Deloukas Panos, Peltonen Leena, Elliott Paul, Coin Lachlan J M, Smith George Davey, Jarvelin Marjo-Riitta   Genome-wide association study reveals multiple loci associated with primary tooth development during infancy PLoS genetics, 2010; 6(2): e1000856.

Congdon Eliza, Poldrack Russell A, Freimer Nelson B   Neurocognitive phenotypes and genetic dissection of disorders of brain and behavior Neuron, 2010; 68(2): 218-30.

Kang Hyun Min, Sul Jae Hoon, Service Susan K, Zaitlen Noah A, Kong Sit-Yee, Freimer Nelson B, Sabatti Chiara, Eskin Eleazar   Variance component model to account for sample structure in genome-wide association studies Nature genetics, 2010; 42(4): 348-54.

Munafò Marcus R, Freimer Nelson B, Ng Whitney, Ophoff Roel, Veijola Juha, Miettunen Jouko, Järvelin Marjo-Riitta, Taanila Anja, Flint Jonathan   5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009; 150B(2): 271-81.

Bilder Robert M, Sabb Fred W, Parker D Stott, Kalar Donald, Chu Wesley W, Fox Jared, Freimer Nelson B, Poldrack Russell A   Cognitive ontologies for neuropsychiatric phenomics research Cognitive neuropsychiatry, 2009; 14(4-5): 419-50.

Stefansson Hreinn, Ophoff Roel A, Steinberg Stacy, Andreassen Ole A, Cichon Sven, Rujescu Dan, Werge Thomas, Pietiläinen Olli P H, Mors Ole, Mortensen Preben B, Sigurdsson Engilbert, Gustafsson Omar, Nyegaard Mette, Tuulio-Henriksson Annamari, Ingason Andres, Hansen Thomas, Suvisaari Jaana, Lonnqvist Jouko, Paunio Tiina, Børglum Anders D, Hartmann Annette, Fink-Jensen Anders, Nordentoft Merete, Hougaard David, Norgaard-Pedersen Bent, Böttcher Yvonne, Olesen Jes, Breuer René, Möller Hans-Jürgen, Giegling Ina, Rasmussen Henrik B, Timm Sally, Mattheisen Manuel, Bitter István, Réthelyi János M, Magnusdottir Brynja B, Sigmundsson Thordur, Olason Pall, Masson Gisli, Gulcher Jeffrey R, Haraldsson Magnus, Fossdal Ragnheidur, Thorgeirsson Thorgeir E, Thorsteinsdottir Unnur, Ruggeri Mirella, Tosato Sarah, Franke Barbara, Strengman Eric, Kiemeney Lambertus A, Kiemeney Lambertus A, Melle Ingrid, Djurovic Srdjan, Abramova Lilia, Kaleda Vasily, Sanjuan Julio, de Frutos Rosa, Bramon Elvira, Vassos Evangelos, Fraser Gillian, Ettinger Ulrich, Picchioni Marco, Walker Nicholas, Toulopoulou Timi, Need Anna C, Ge Dongliang, Yoon Joeng Lim, Shianna Kevin V, Freimer Nelson B, Cantor Rita M, Murray Robin, Kong Augustine, Golimbet Vera, Carracedo Angel, Arango Celso, Costas Javier, Jönsson Erik G, Terenius Lars, Agartz Ingrid, Petursson Hannes, Nöthen Markus M, Rietschel Marcella, Matthews Paul M, Muglia Pierandrea, Peltonen Leena, St Clair David, Goldstein David B, Stefansson Kari, Collier David A   Common variants conferring risk of schizophrenia Nature, 2009; 460(7256): 744-7.

Elliott Paul, Chambers John C, Zhang Weihua, Clarke Robert, Hopewell Jemma C, Peden John F, Erdmann Jeanette, Braund Peter, Engert James C, Bennett Derrick, Coin Lachlan, Ashby Deborah, Tzoulaki Ioanna, Brown Ian J, Mt-Isa Shahrul, McCarthy Mark I, Peltonen Leena, Freimer Nelson B, Farrall Martin, Ruokonen Aimo, Hamsten Anders, Lim Noha, Froguel Philippe, Waterworth Dawn M, Vollenweider Peter, Waeber Gerard, Jarvelin Marjo-Riitta, Mooser Vincent, Scott James, Hall Alistair S, Schunkert Heribert, Anand Sonia S, Collins Rory, Samani Nilesh J, Watkins Hugh, Kooner Jaspal S   Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease JAMA : the journal of the American Medical Association, 2009; 302(1): 37-48.

Sovio Ulla, Bennett Amanda J, Millwood Iona Y, Molitor John, O’Reilly Paul F, Timpson Nicholas J, Kaakinen Marika, Laitinen Jaana, Haukka Jari, Pillas Demetris, Tzoulaki Ioanna, Molitor Jassy, Hoggart Clive, Coin Lachlan J M, Whittaker John, Pouta Anneli, Hartikainen Anna-Liisa, Freimer Nelson B, Widen Elisabeth, Peltonen Leena, Elliott Paul, McCarthy Mark I, Jarvelin Marjo-Riitta   Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966 PLoS genetics, 2009; 5(3): e1000409.

Sabatti Chiara, Service Susan K, Hartikainen Anna-Liisa, Pouta Anneli, Ripatti Samuli, Brodsky Jae, Jones Chris G, Zaitlen Noah A, Varilo Teppo, Kaakinen Marika, Sovio Ulla, Ruokonen Aimo, Laitinen Jaana, Jakkula Eveliina, Coin Lachlan, Hoggart Clive, Collins Andrew, Turunen Hannu, Gabriel Stacey, Elliot Paul, McCarthy Mark I, Daly Mark J, Järvelin Marjo-Riitta, Freimer Nelson B, Peltonen Leena   Genome-wide association analysis of metabolic traits in a birth cohort from a founder population Nature genetics, 2009; 41(1): 35-46.

Newton-Cheh Christopher, Johnson Toby, Gateva Vesela, Tobin Martin D, Bochud Murielle, Coin Lachlan, Najjar Samer S, Zhao Jing Hua, Heath Simon C, Eyheramendy Susana, Papadakis Konstantinos, Voight Benjamin F, Scott Laura J, Zhang Feng, Farrall Martin, Tanaka Toshiko, Wallace Chris, Chambers John C, Khaw Kay-Tee, Nilsson Peter, van der Harst Pim, Polidoro Silvia, Grobbee Diederick E, Onland-Moret N Charlotte, Bots Michiel L, Wain Louise V, Elliott Katherine S, Teumer Alexander, Luan Jian’an, Lucas Gavin, Kuusisto Johanna, Burton Paul R, Hadley David, McArdle Wendy L, McArdle Wendy L, Brown Morris, Dominiczak Anna, Newhouse Stephen J, Samani Nilesh J, Webster John, Zeggini Eleftheria, Beckmann Jacques S, Bergmann Sven, Lim Noha, Song Kijoung, Vollenweider Peter, Waeber Gerard, Waterworth Dawn M, Yuan Xin, Groop Leif, Orho-Melander Marju, Allione Alessandra, Di Gregorio Alessandra, Guarrera Simonetta, Panico Salvatore, Ricceri Fulvio, Romanazzi Valeria, Sacerdote Carlotta, Vineis Paolo, Barroso Inês, Sandhu Manjinder S, Luben Robert N, Crawford Gabriel J, Jousilahti Pekka, Perola Markus, Boehnke Michael, Bonnycastle Lori L, Collins Francis S, Jackson Anne U, Mohlke Karen L, Stringham Heather M, Valle Timo T, Willer Cristen J, Bergman Richard N, Morken Mario A, Döring Angela, Gieger Christian, Illig Thomas, Meitinger Thomas, Org Elin, Pfeufer Arne, Wichmann H Erich, Kathiresan Sekar, Marrugat Jaume, O’Donnell Christopher J, Schwartz Stephen M, Siscovick David S, Subirana Isaac, Freimer Nelson B, Hartikainen Anna-Liisa, McCarthy Mark I, O’Reilly Paul F, Peltonen Leena, Pouta Anneli, de Jong Paul E, Snieder Harold, van Gilst Wiek H, Clarke Robert, Goel Anuj, Hamsten Anders, Peden John F, Seedorf Udo, Syvänen Ann-Christine, Tognoni Giovanni, Lakatta Edward G, Sanna Serena, Scheet Paul, Schlessinger David, Scuteri Angelo, Dörr Marcus, Ernst Florian, Felix Stephan B, Homuth Georg, Lorbeer Roberto, Reffelmann Thorsten, Rettig Rainer, Völker Uwe, Galan Pilar, Gut Ivo G, Hercberg Serge, Lathrop G Mark, Zelenika Diana, Deloukas Panos, Soranzo Nicole, Williams Frances M, Zhai Guangju, Salomaa Veikko, Laakso Markku, Elosua Roberto, Forouhi Nita G, Völzke Henry, Uiterwaal Cuno S, van der Schouw Yvonne T, Numans Mattijs E, Matullo Giuseppe, Navis Gerjan, Berglund Göran, Bingham Sheila A, Kooner Jaspal S, Connell John M, Bandinelli Stefania, Ferrucci Luigi, Watkins Hugh, Spector Tim D, Tuomilehto Jaakko, Altshuler David, Strachan David P, Laan Maris, Meneton Pierre, Wareham Nicholas J, Uda Manuela, Jarvelin Marjo-Riitta, Mooser Vincent, Melander Olle, Loos Ruth J F, Elliott Paul, Abecasis Gonçalo R, Caulfield Mark, Munroe Patricia B   Genome-wide association study identifies eight loci associated with blood pressure Nature genetics, 2009; 41(6): 666-76.

Chambers John C, Zhang Weihua, Li Yun, Sehmi Joban, Wass Mark N, Zabaneh Delilah, Hoggart Clive, Bayele Henry, McCarthy Mark I, Peltonen Leena, Freimer Nelson B, Srai Surjit K, Maxwell Patrick H, Sternberg Michael J E, Ruokonen Aimo, Abecasis Gonçalo, Jarvelin Marjo-Riitta, Scott James, Elliott Paul, Kooner Jaspal S   Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels Nature genetics, 2009; 41(11): 1170-2.

Jasinska Anna J, Service Susan, Choi Oi-wa, DeYoung Joseph, Grujic Olivera, Kong Sit-yee, Jorgensen Matthew J, Bailey Julia, Breidenthal Sherry, Fairbanks Lynn A, Woods Roger P, Jentsch J David, Freimer Nelson B   Identification of brain transcriptional variation reproduced in peripheral blood: an approach for mapping brain expression traits Human molecular genetics, 2009; 18(22): 4415-27.

Fears Scott C, Melega William P, Service Susan K, Lee Chris, Chen Kelly, Tu Zhuowen, Jorgensen Matthew J, Fairbanks Lynn A, Cantor Rita M, Freimer Nelson B, Woods Roger P   Identifying heritable brain phenotypes in an extended pedigree of vervet monkeys The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(9): 2867-75.

Nyman Emma S, Loukola Anu, Varilo Teppo, Ekelund Jesper, Veijola Juha, Joukamaa Matti, Taanila Anja, Pouta Anneli, Miettunen Jouko, Freimer Nelson, Järvelin Marjo-Riitta, Peltonen Leena   Impact of the dopamine receptor gene family on temperament traits in a population-based birth cohort American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009; 150B(6): 854-65.

Aulchenko Yurii S, Ripatti Samuli, Lindqvist Ida, Boomsma Dorret, Heid Iris M, Pramstaller Peter P, Penninx Brenda W J H, Janssens A Cecile J W, Wilson James F, Spector Tim, Martin Nicholas G, Pedersen Nancy L, Kyvik Kirsten Ohm, Kaprio Jaakko, Hofman Albert, Freimer Nelson B, Jarvelin Marjo-Riitta, Gyllensten Ulf, Campbell Harry, Rudan Igor, Johansson Asa, Marroni Fabio, Hayward Caroline, Vitart Veronique, Jonasson Inger, Pattaro Cristian, Wright Alan, Hastie Nick, Pichler Irene, Hicks Andrew A, Falchi Mario, Willemsen Gonneke, Hottenga Jouke-Jan, de Geus Eco J C, Montgomery Grant W, Whitfield John, Magnusson Patrik, Saharinen Juha, Perola Markus, Silander Kaisa, Isaacs Aaron, Sijbrands Eric J G, Uitterlinden Andre G, Witteman Jacqueline C M, Oostra Ben A, Elliott Paul, Ruokonen Aimo, Sabatti Chiara, Gieger Christian, Meitinger Thomas, Kronenberg Florian, Döring Angela, Wichmann H-Erich, Smit Johannes H, McCarthy Mark I, van Duijn Cornelia M, Peltonen Leena, Peltonen Leena   Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts Nature genetics, 2009; 41(1): 47-55.

Bearden Carrie E, Jasinska Anna J, Freimer Nelson B   Methodological issues in molecular genetic studies of mental disorders Annual review of clinical psychology, 2009; 5(1): 49-69.

Kerner Berit, Jasinska Anna J, DeYoung Joseph, Almonte Maricel, Choi Oi-Wa, Freimer Nelson B   Polymorphisms in the GRIA1 gene region in psychotic bipolar disorder American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009; 150B(1): 24-32.

Jasinska Anna J, Freimer Nelson B   The complex genetic basis of simple behavior Journal of biology, 2009; 8(8): 71.

Prokopenko Inga, Langenberg Claudia, Florez Jose C, Saxena Richa, Soranzo Nicole, Thorleifsson Gudmar, Loos Ruth J F, Manning Alisa K, Jackson Anne U, Aulchenko Yurii, Potter Simon C, Erdos Michael R, Sanna Serena, Hottenga Jouke-Jan, Wheeler Eleanor, Kaakinen Marika, Lyssenko Valeriya, Chen Wei-Min, Ahmadi Kourosh, Beckmann Jacques S, Bergman Richard N, Bochud Murielle, Bonnycastle Lori L, Buchanan Thomas A, Cao Antonio, Cervino Alessandra, Coin Lachlan, Collins Francis S, Crisponi Laura, de Geus Eco J C, Dehghan Abbas, Deloukas Panos, Doney Alex S F, Elliott Paul, Freimer Nelson, Gateva Vesela, Herder Christian, Hofman Albert, Hughes Thomas E, Hunt Sarah, Illig Thomas, Inouye Michael, Isomaa Bo, Johnson Toby, Kong Augustine, Krestyaninova Maria, Kuusisto Johanna, Laakso Markku, Lim Noha, Lindblad Ulf, Lindgren Cecilia M, McCann Owen T, Mohlke Karen L, Morris Andrew D, Naitza Silvia, Orrù Marco, Palmer Colin N A, Pouta Anneli, Randall Joshua, Rathmann Wolfgang, Saramies Jouko, Scheet Paul, Scott Laura J, Scuteri Angelo, Sharp Stephen, Sijbrands Eric, Smit Jan H, Song Kijoung, Steinthorsdottir Valgerdur, Stringham Heather M, Tuomi Tiinamaija, Tuomilehto Jaakko, Uitterlinden André G, Voight Benjamin F, Waterworth Dawn, Wichmann H-Erich, Willemsen Gonneke, Witteman Jacqueline C M, Yuan Xin, Zhao Jing Hua, Zeggini Eleftheria, Schlessinger David, Sandhu Manjinder, Boomsma Dorret I, Uda Manuela, Spector Tim D, Penninx Brenda Wjh, Altshuler David, Vollenweider Peter, Jarvelin Marjo Riitta, Lakatta Edward, Waeber Gerard, Fox Caroline S, Peltonen Leena, Groop Leif C, Mooser Vincent, Cupples L Adrienne, Thorsteinsdottir Unnur, Boehnke Michael, Barroso Inês, Van Duijn Cornelia, Dupuis Josée, Watanabe Richard M, Stefansson Kari, McCarthy Mark I, Wareham Nicholas J, Meigs James B, Abecasis Gonçalo R   Variants in MTNR1B influence fasting glucose levels Nature genetics, 2009; 41(1): 77-81.

Jarvik Lissy, LaRue Asenath, Blacker Deborah, Gatz Margaret, Kawas Claudia, McArdle John J, Morris John C, Mortimer James A, Ringman John M, Ercoli Linda, Freimer Nelson, Gokhman Izabella, Manly Jennifer J, Plassman Brenda L, Rasgon Natalie, Roberts Jeffrey Scott, Sunderland Trey, Swan Gary E, Wolf Phillip A, Zonderman Alan B   Children of persons with Alzheimer disease: what does the future hold? Alzheimer disease and associated disorders, 2008; 22(1): 6-20.

Cotton Richard G H, Auerbach Arleen D, Axton Myles, Barash Carol Isaacson, Berkovic Samuel F, Brookes Anthony J, Burn John, Cutting Garry, den Dunnen Johan T, Flicek Paul, Freimer Nelson, Greenblatt Marc S, Howard Heather J, Katz Michael, Macrae Finlay A, Maglott Donna, Möslein Gabriela, Povey Sue, Ramesar Rajkumar S, Richards Carolyn S, Seminara Daniela, Smith Timothy D, Sobrido María-Jesús, Solbakk Jan Helge, Tanzi Rudolph E, Tavtigian Sean V, Taylor Graham R, Utsunomiya Joji, Watson Michael   GENETICS. The Human Variome Project Science (New York, N.Y.), 2008; 322(5903): 861-2.

Wang Sijia, Ray Nicolas, Rojas Winston, Parra Maria V, Bedoya Gabriel, Gallo Carla, Poletti Giovanni, Mazzotti Guido, Hill Kim, Hurtado Ana M, Camrena Beatriz, Nicolini Humberto, Klitz William, Barrantes Ramiro, Molina Julio A, Freimer Nelson B, Bortolini Maria Cátira, Salzano Francisco M, Petzl-Erler Maria L, Tsuneto Luiza T, Dipierri José E, Alfaro Emma L, Bailliet Graciela, Bianchi Nestor O, Llop Elena, Rothhammer Francisco, Excoffier Laurent, Ruiz-Linares Andrés   Geographic patterns of genome admixture in Latin American Mestizos PLoS genetics, 2008; 4(3): e1000037.

Stefansson Hreinn, Rujescu Dan, Cichon Sven, Pietiläinen Olli P H, Ingason Andres, Steinberg Stacy, Fossdal Ragnheidur, Sigurdsson Engilbert, Sigmundsson Thordur, Buizer-Voskamp Jacobine E, Hansen Thomas, Jakobsen Klaus D, Muglia Pierandrea, Francks Clyde, Matthews Paul M, Gylfason Arnaldur, Halldorsson Bjarni V, Gudbjartsson Daniel, Thorgeirsson Thorgeir E, Sigurdsson Asgeir, Jonasdottir Adalbjorg, Jonasdottir Aslaug, Bjornsson Asgeir, Mattiasdottir Sigurborg, Blondal Thorarinn, Haraldsson Magnus, Magnusdottir Brynja B, Giegling Ina, Möller Hans-Jürgen, Hartmann Annette, Shianna Kevin V, Ge Dongliang, Need Anna C, Crombie Caroline, Fraser Gillian, Walker Nicholas, Lonnqvist Jouko, Suvisaari Jaana, Tuulio-Henriksson Annamarie, Paunio Tiina, Toulopoulou Timi, Bramon Elvira, Di Forti Marta, Murray Robin, Ruggeri Mirella, Vassos Evangelos, Tosato Sarah, Walshe Muriel, Li Tao, Vasilescu Catalina, Mühleisen Thomas W, Wang August G, Ullum Henrik, Djurovic Srdjan, Melle Ingrid, Olesen Jes, Kiemeney Lambertus A, Franke Barbara, Franke Barbara, Sabatti Chiara, Freimer Nelson B, Gulcher Jeffrey R, Thorsteinsdottir Unnur, Kong Augustine, Andreassen Ole A, Ophoff Roel A, Georgi Alexander, Rietschel Marcella, Werge Thomas, Petursson Hannes, Goldstein David B, Nöthen Markus M, Peltonen Leena, Collier David A, St Clair David, Stefansson Kari   Large recurrent microdeletions associated with schizophrenia Nature, 2008; 455(7210): 232-6.

Hunninghake Gary M, Lasky-Su Jessica, Soto-Quirós Manuel E, Avila Lydiana, Liang Catherine, Lake Stephen L, Hudson Thomas J, Spesny Mitzi, Fournier Eduardo, Sylvia Jody S, Freimer Nelson B, Klanderman Barbara J, Raby Benjamin A, Celedón Juan C   Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans American journal of respiratory and critical care medicine, 2008; 177(8): 830-6.

Jakkula Eveliina, Rehnström Karola, Varilo Teppo, Pietiläinen Olli P H, Paunio Tiina, Pedersen Nancy L, deFaire Ulf, Järvelin Marjo-Riitta, Saharinen Juha, Freimer Nelson, Ripatti Samuli, Purcell Shaun, Collins Andrew, Daly Mark J, Palotie Aarno, Peltonen Leena   The genome-wide patterns of variation expose significant substructure in a founder population American journal of human genetics, 2008; 83(6): 787-94.

Jasinska Anna J, Service Susan, Levinson Matthew, Slaten Erin, Lee Oliver, Sobel Eric, Fairbanks Lynn A, Bailey Julia N, Jorgensen Matthew J, Breidenthal Sherry E, Dewar Ken, Hudson Thomas J, Palmour Roberta, Freimer Nelson B, Ophoff Roel A   A genetic linkage map of the vervet monkey (Chlorocebus aethiops sabaeus) Mammalian genome : official journal of the International Mammalian Genome Society, 2007; 18(5): 347-60.

Freimer Nelson B, Service Susan K, Ophoff Roel A, Jasinska Anna J, McKee Kevin, Villeneuve Amelie, Belisle Alexandre, Bailey Julia N, Breidenthal Sherry E, Jorgensen Matthew J, Mann J John, Cantor Rita M, Dewar Ken, Fairbanks Lynn A   A quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(40): 15811-6.

Mehan Michael R, Almonte Maricel, Slaten Erin, Freimer Nelson B, Rao P Nagesh, Ophoff Roel A   Analysis of segmental duplications reveals a distinct pattern of continuation-of-synteny between human and mouse genomes Human genetics, 2007; 121(1): 93-100.

Athos E Alexandra, Levinson Barbara, Kistler Amy, Zemansky Jason, Bostrom Alan, Freimer Nelson, Gitschier Jane   Dichotomy and perceptual distortions in absolute pitch ability Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(37): 14795-800.

Kerner Berit, Brugman Diana L, Freimer Nelson B   Evidence of linkage to psychosis on chromosome 5q33-34 in pedigrees ascertained for bipolar disorder American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2007; 144B(1): 74-8.

Hersh Craig P, Soto-Quirós Manuel E, Avila Lydiana, Lake Stephen L, Liang Catherine, Fournier Eduardo, Spesny Mitzi, Sylvia Jody S, Lazarus Ross, Hudson Thomas, Verner Andrei, Klanderman Barbara J, Freimer Nelson B, Silverman Edwin K, Celedón Juan C   Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica Thorax, 2007; 62(3): 224-30.

Freimer Nelson B, Sabatti Chiara   Human genetics: variants in common diseases Nature, 2007; 445(7130): 828-30.

Gitschier Jane, Chanock Stephen J, Manolio Teri, Boehnke Michael, Boerwinkle Eric, Hunter David J, Thomas Gilles, Hirschhorn Joel N, Abecasis Goncalo, Altshuler David, Bailey-Wilson Joan E, Brooks Lisa D, Cardon Lon R, Daly Mark, Donnelly Peter, Fraumeni Joseph F, Freimer Nelson B, Gerhard Daniela S, Gunter Chris, Guttmacher Alan E, Guyer Mark S, Harris Emily L, Hoh Josephine, Hoover Robert, Kong C Augustine, Merikangas Kathleen R, Morton Cynthia C, Palmer Lyle J, Phimister Elizabeth G, Rice John P, Roberts Jerry, Rotimi Charles, Tucker Margaret A, Vogan Kyle J, Wacholder Sholom, Wijsman Ellen M, Winn Deborah M, Collins Francis S   Replicating genotype-phenotype associations Nature, 2007; 447(7145): 655-60.

Raby Benjamin A, Soto-Quiros Manuel E, Avila Lydiana, Lake Stephen L, Murphy Amy, Liang Catherine, Fournier Eduardo, Spesny Mitzi, Sylvia Jody S, Verner Andrei, Hudson Thomas J, Klanderman Barbara J, Freimer Nelson B, Silverman Edwin K, Celedón Juan C   Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica Human molecular genetics, 2007; 16(3): 243-53.

Celedón Juan C, Soto-Quiros Manuel E, Avila Lydiana, Lake Stephen L, Liang Catherine, Fournier Eduardo, Spesny Mitzi, Hersh Craig P, Sylvia Jody S, Hudson Thomas J, Verner Andrei, Klanderman Barbara J, Freimer Nelson B, Silverman Edwin K, Weiss Scott T   Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica Human genetics, 2007; 120(5): 691-9.

Service Susan, Service Susan, Sabatti Chiara, Freimer Nelson   Tag SNPs chosen from HapMap perform well in several population isolates Genetic epidemiology, 2007; 31(3): 189-94.

Mathews Carol A, Jang Kerry L, Herrera Luis Diego, Lowe Thomas L, Budman Cathy L, Erenberg Gerald, Naarden Allan, Bruun Ruth D, Schork Nicholas J, Freimer Nelson B, Reus Victor I   Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populations Biological psychiatry, 2007; 61(3): 292-300.

Mathews Carol A, Bimson Brianne, Lowe Thomas L, Herrera Luis Diego, Budman Cathy L, Erenberg Gerald, Naarden Allen, Bruun Ruth D, Freimer Nelson B, Reus Victor I   Association between maternal smoking and increased symptom severity in Tourette’s syndrome The American journal of psychiatry, 2006; 163(6): 1066-73.

Herzberg Ibi, Jasinska Anna, García Jenny, Jawaheer Damini, Service Susan, Kremeyer Barbara, Duque Constanza, Parra María V, Vega Jorge, Ortiz Daniel, Carvajal Luis, Polanco Guadalupe, Restrepo Gabriel J, López Carlos, Palacio Carlos, Levinson Matthew, Aldana Ileana, Mathews Carol, Davanzo Pablo, Molina Julio, Fournier Eduardo, Bejarano Julio, Ramírez Magui, Ortiz Carmen Araya, Araya Xinia, Sabatti Chiara, Reus Victor, Macaya Gabriel, Bedoya Gabriel, Ospina Jorge, Freimer Nelson, Ruiz-Linares Andrés   Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34 Human molecular genetics, 2006; 15(21): 3146-53.

Bearden Carrie E, Freimer Nelson B   Endophenotypes for psychiatric disorders: ready for primetime? Trends in genetics : TIG, 2006; 22(6): 306-13.

Keen-Kim Dianne, Freimer Nelson B   Genetics and epidemiology of Tourette syndrome Journal of child neurology, 2006; 21(8): 665-71.

Wang Hui, Lin Chia-Ho, Service Susan, Chen Yuguo, Freimer Nelson, Sabatti Chiara, Sabatti Chiara   Linkage disequilibrium and haplotype homozygosity in population samples genotyped at a high marker density Human heredity, 2006; 62(4): 175-89.

Service Susan, DeYoung Joseph, Karayiorgou Maria, Roos J Louw, Pretorious Herman, Bedoya Gabriel, Ospina Jorge, Ruiz-Linares Andres, Macedo António, Palha Joana Almeida, Heutink Peter, Aulchenko Yurii, Oostra Ben, van Duijn Cornelia, Jarvelin Marjo-Riitta, Varilo Teppo, Peddle Lynette, Rahman Proton, Piras Giovanna, Monne Maria, Murray Sarah, Galver Luana, Peltonen Leena, Sabatti Chiara, Collins Andrew, Freimer Nelson   Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies Nature genetics, 2006; 38(5): 556-60.

Woods Roger P, Freimer Nelson B, De Young Joseph A, Fears Scott C, Sicotte Nancy L, Service Susan K, Valentino Daniel J, Toga Arthur W, Mazziotta John C   Normal variants of Microcephalin and ASPM do not account for brain size variability Human molecular genetics, 2006; 15(12): 2025-9.

Keen-Kim Dianne, Mathews Carol A, Reus Victor I, Lowe Thomas L, Herrera Luis Diego, Budman Cathy L, Gross-Tsur Varda, Pulver Ann E, Bruun Ruth D, Erenberg Gerald, Naarden Allan, Sabatti Chiara, Freimer Nelson B   Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses Human molecular genetics, 2006; 15(22): 3324-8.

Service Susan, Molina Julio, Deyoung Joseph, Jawaheer Damini, Aldana Ileana, Vu Thuy, Araya Carmen, Araya Xinia, Bejarano Julio, Fournier Eduardo, Ramirez Magui, Mathews Carol A, Davanzo Pablo, Macaya Gabriel, Sandkuijl Lodewijk, Sabatti Chiara, Reus Victor, Freimer Nelson   Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2006; 141B(4): 367-73.

Glatt Charles, Almonte Maricel, Taylor Travis, Edwards Robert H, Freimer Nelson, Tanner Caroline, Tanner Caroline   Structural variants in the vesicular monoamine transporter do not contribute to sporadic Parkinson’s disease Movement disorders : official journal of the Movement Disorder Society, 2006; 21(3): 426-7.

Freimer Nelson B, Sabatti Chiara   Guidelines for association studies in Human Molecular Genetics Human molecular genetics, 2005; 14(17): 2481-3.

Jarvik Lissy F, La Rue Asenath, Gokhman Izabella, Harrison Tracy, Holt Lori, Steh Bill, Harker Judith, Larson Scott, Yaralian Pauline, Matsuyama Steven, Rasgon Natalie, Geschwind Daniel, Freimer Nelson, Jimenez Elvira, Schaeffer Jeffrey   Middle-aged children of Alzheimer parents, a pilot study: stable neurocognitive performance at 20-year follow-up Journal of geriatric psychiatry and neurology, 2005; 18(4): 187-91.

Mehan Michael R, Freimer Nelson B, Ophoff Roel A   A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture Human genomics, 2004; 1(5): 335-44.

Pawlikowska Ludmila, Groen Annemiek, Eppens Elaine F, Kunne Cindy, Ottenhoff Roelof, Looije Norbert, Knisely A S, Killeen Nigel P, Bull Laura N, Elferink Ronald P J Oude, Freimer Nelson B   A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion Human molecular genetics, 2004; 13(8): 881-92.

Klomp Leo W J, Vargas Julie C, van Mil Saskia W C, Pawlikowska Ludmila, Strautnieks Sandra S, van Eijk Michiel J T, Juijn Jenneke A, Pabón-Peña Carlos, Smith Lauren B, DeYoung Joseph A, Byrne Jane A, Gombert Justijn, van der Brugge Gerda, Berger Ruud, Jankowska Irena, Pawlowska Joanna, Villa Erica, Knisely A S, Thompson Richard J, Freimer Nelson B, Houwen Roderick H J, Bull Laura N   Characterization of mutations in ATP8B1 associated with hereditary cholestasis Hepatology (Baltimore, Md.), 2004; 40(1): 27-38.

Hong Kyung Sue, McInnes L Alison, Service Susan K, Song Terry, Lucas Jennifer, Silva Sandra, Fournier Eduardo, León Pedro, Molina Julio, Reus Victor I, Sandkuijl Lodewijk A, Freimer Nelson B   Genetic mapping using haplotype and model-free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31-33 American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2004; 125B(1): 83-6.

Mathews Carol A, Reus Victor I, Bejarano Julio, Escamilla Michael A, Fournier Eduardo, Herrera Luis Diego, Lowe Thomas L, McInnes L Alison, Molina Julio, Ophoff Roel A, Raventos Henrietta, Sandkuijl Lodewijk A, Service Susan K, Spesny Mitzi, León Pedro E, Freimer Nelson B   Genetic studies of neuropsychiatric disorders in Costa Rica: a model for the use of isolated populations Psychiatric genetics, 2004; 14(1): 13-23.

Glatt Charles E, Tampilic Maricel, Christie Carroll, DeYoung Joe, Freimer Nelson B   Re-screening serotonin receptors for genetic variants identifies population and molecular genetic complexity American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2004; 124B(1): 92-100.

Burman Jonathon, Tran Cindy H, Glatt Charles, Freimer Nelson B, Edwards Robert H   The effect of rare human sequence variants on the function of vesicular monoamine transporter 2 Pharmacogenetics, 2004; 14(9): 587-94.

Freimer Nelson, Sabatti Chiara   The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology Nature genetics, 2004; 36(10): 1045-51.

Bearden Carrie E, Reus Victor I, Freimer Nelson B   Why genetic investigation of psychiatric disorders is so difficult Current opinion in genetics & development, 2004; 14(3): 280-6.

Service Susan K, Sandkuijl Lodewijk A, Freimer Nelson B   Cost-effective designs for linkage disequilibrium mapping of complex traits American journal of human genetics, 2003; 72(5): 1213-20.

Sabatti Chiara, Service Susan, Freimer Nelson   False discovery rate in linkage and association genome screens for complex disorders Genetics, 2003; 164(2): 829-33.

Carvajal-Carmona Luis G, Ophoff Roel, Service Susan, Hartiala Jaana, Molina Julio, Leon Pedro, Ospina Jorge, Bedoya Gabriel, Freimer Nelson, Ruiz-Linares Andrés   Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica Human genetics, 2003; 112(5-6): 534-41.

Segurado Ricardo, Detera-Wadleigh Sevilla D, Levinson Douglas F, Lewis Cathryn M, Gill Michael, Nurnberger John I, Craddock Nick, DePaulo J Raymond, Baron Miron, Gershon Elliot S, Ekholm Jenny, Cichon Sven, Turecki Gustavo, Claes Stephan, Kelsoe John R, Schofield Peter R, Badenhop Renee F, Morissette J, Coon Hilary, Blackwood Douglas, McInnes L Alison, Foroud Tatiana, Edenberg Howard J, Reich Theodore, Rice John P, Goate Alison, McInnis Melvin G, McMahon Francis J, Badner Judith A, Goldin Lynn R, Bennett Phil, Willour Virginia L, Zandi Peter P, Liu Jianjun, Gilliam Conrad, Juo Suh-Hang, Berrettini Wade H, Yoshikawa Takeo, Peltonen Leena, Lönnqvist Jouko, Nöthen Markus M, Schumacher Johannes, Windemuth Christine, Rietschel Marcella, Propping Peter, Maier Wolfgang, Alda Martin, Grof Paul, Rouleau Guy A, Del-Favero Jurgen, Van Broeckhoven Christine, Mendlewicz Julien, Adolfsson Rolf, Spence M Anne, Luebbert Hermann, Adams Linda J, Donald Jennifer A, Mitchell Philip B, Barden Nicholas, Shink Eric, Byerley William, Muir Walter, Visscher Peter M, Macgregor Stuart, Gurling Hugh, Kalsi Gursharan, McQuillin Andrew, Escamilla Michael A, Reus Victor I, Leon Pedro, Freimer Nelson B, Ewald Henrik, Kruse Torben A, Mors Ole, Radhakrishna Uppala, Blouin Jean-Louis, Antonarakis Stylianos E, Akarsu Nurten   Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder American journal of human genetics, 2003; 73(1): 49-62.

Rahman Proton, Jones Albert, Curtis Joseph, Bartlett Sylvia, Peddle Lynette, Fernandez Bridget A, Freimer Nelson B   The Newfoundland population: a unique resource for genetic investigation of complex diseases Human molecular genetics, 2003; 12 Spec No 2(1): R167-72.

Freimer Nelson, Sabatti Chiara   The human phenome project Nature genetics, 2003; 34(1): 15-21.

Glatt Charles E, Freimer Nelson B   Association analysis of candidate genes for neuropsychiatric disease: the perpetual campaign Trends in genetics : TIG, 2002; 18(6): 307-12.

Escamilla Michael A, Batki Steven, Reus Victor I, Spesny Mitzi, Molina Julio, Service Susan, Vinogradov Sophia, Neylan Tom, Mathews Carol, Meza Luis, Gallegos Alvaro, Montero A Patricia, Cruz Maria L, Neuhaus John, Roche Erin, Smith Lauren, Leon Pedro, Freimer Nelson B   Comorbidity of bipolar disorder and substance abuse in Costa Rica: pedigree- and population-based studies Journal of affective disorders, 2002; 71(1-3): 71-83.

Merikangas Kathleen R, Chakravarti Aravinda, Moldin Steven O, Araj Houmam, Blangero John C, Burmeister Margit, Crabbe John, Depaulo J Raymond, Foulks Edward, Freimer Nelson B, Koretz Doreen S, Lichtenstein William, Mignot Emmanuel, Reiss Allan L, Risch Neil J, Takahashi Joseph S   Future of genetics of mood disorders research Biological psychiatry, 2002; 52(6): 457-77.

Ophoff Roel A, Escamilla Michael A, Service Susan K, Spesny Mitzi, Meshi Dar B, Poon Wingman, Molina Julio, Fournier Eduardo, Gallegos Alvaro, Mathews Carol, Neylan Thomas, Batki Steven L, Roche Erin, Ramirez Margarita, Silva Sandra, De Mille Melissa C, Dong Penny, Leon Pedro E, Reus Victor I, Sandkuijl Lodewijk A, Freimer Nelson B   Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate American journal of human genetics, 2002; 71(3): 565-74.

Glatt, CE DeYoung, JA Delgado, S Service, SK Giacomini, KM Edwards, RH Risch, N Freimer, NB   Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes Nature genetics. , 2001; 27(4): 435-8.

Service, SK Ophoff, RA Freimer, NB   The genome-wide distribution of background linkage disequilibrium in a population isolate Human molecular genetics. , 2001; 10(5): 545-51.

Baharloo S, Johnston PA, Service SK, Gitschier J, Freimer NB   Absolute Pitch: An approach for identifying genetic and non-genetic components, Am J Hum Genet, 1998; 62(2): 224-231.

Yu Dongmei, Mathews Carol A, Scharf Jeremiah M, Neale Benjamin M, Davis Lea K, Gamazon Eric R, Derks Eske M, Evans Patrick, Edlund Christopher K, Crane Jacquelyn, Fagerness Jesen A, Osiecki Lisa, Gallagher Patience, Gerber Gloria, Haddad Stephen, Illmann Cornelia, McGrath Lauren M, Mayerfeld Catherine, Arepalli Sampath, Barlassina Cristina, Barr Cathy L, Bellodi Laura, Benarroch Fortu, Berrió Gabriel Bedoya, Bienvenu O Joseph, Black Donald W, Bloch Michael H, Brentani Helena, Bruun Ruth D, Budman Cathy L, Camarena Beatriz, Campbell Desmond D, Cappi Carolina, Silgado Julio C Cardona, Cavallini Maria C, Chavira Denise A, Chouinard Sylvain, Cook Edwin H, Cookson M R, Coric Vladimir, Cullen Bernadette, Cusi Daniele, Delorme Richard, Denys Damiaan, Dion Yves, Eapen Valsama, Egberts Karin, Falkai Peter, Fernandez Thomas, Fournier Eduardo, Garrido Helena, Geller Daniel, Gilbert Donald L, Girard Simon L, Grabe Hans J, Grados Marco A, Greenberg Benjamin D, Gross-Tsur Varda, Grünblatt Edna, Hardy John, Heiman Gary A, Hemmings Sian M J, Herrera Luis D, Hezel Dianne M, Hoekstra Pieter J, Jankovic Joseph, Kennedy James L, King Robert A, Konkashbaev Anuar I, Kremeyer Barbara, Kurlan Roger, Lanzagorta Nuria, Leboyer Marion, Leckman James F, Lennertz Leonhard, Liu Chunyu, Lochner Christine, Lowe Thomas L, Lupoli Sara, Macciardi Fabio, Maier Wolfgang, Manunta Paolo, Marconi Maurizio, McCracken James T, Mesa Restrepo Sandra C, Moessner Rainald, Moorjani Priya, Morgan Jubel, Muller Heike, Murphy Dennis L, Naarden Allan L, Nurmi Erika, Ochoa William Cornejo, Ophoff Roel A, Pakstis Andrew J, Pato Michele T, Pato Carlos N, Piacentini John, Pittenger Christopher, Pollak Yehuda, Rauch Scott L, Renner Tobias, Reus Victor I, Richter Margaret A, Riddle Mark A, Robertson Mary M, Romero Roxana, Rosário Maria C, Rosenberg David, Ruhrmann Stephan, Sabatti Chiara, Salvi Erika, Sampaio Aline S, Samuels Jack, Sandor Paul, Service Susan K, Sheppard Brooke, Singer Harvey S, Smit Jan H, Stein Dan J, Strengman Eric, Tischfield Jay A, Turiel Maurizio, Valencia Duarte Ana V, Vallada Homero, Veenstra-VanderWeele Jeremy, Walitza Susanne, Wang Ying, Weale Mike, Weiss Robert, Wendland Jens R, Westenberg Herman G M, Shugart Yin Yao, Hounie Ana G, Miguel Euripedes C, Nicolini Humberto, Wagner Michael, Ruiz-Linares Andres, Cath Danielle C, McMahon William, Posthuma Danielle, Oostra Ben A, Nestadt Gerald, Rouleau Guy A, Purcell Shaun, Jenike Michael A, Heutink Peter, Hanna Gregory L, Conti David V, Arnold Paul D, Freimer Nelson B, Stewart S Evelyn, Knowles James A, Cox Nancy J, Pauls David L   Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette’s Syndrome and OCD The American journal of psychiatry, 2015; 172(1): 82-93.

Paschou Peristera, Yu Dongmei, Gerber Gloria, Evans Patrick, Tsetsos Fotis, Davis Lea K, Karagiannidis Iordanis, Chaponis Jonathan, Gamazon Eric, Mueller-Vahl Kirsten, Stuhrmann Manfred, Schloegelhofer Monika, Stamenkovic Mara, Hebebrand Johannes, Noethen Markus, Nagy Peter, Barta Csaba, Tarnok Zsanett, Rizzo Renata, Depienne Christel, Worbe Yulia, Hartmann Andreas, Cath Danielle C, Budman Cathy L, Sandor Paul, Barr Cathy, Wolanczyk Thomas, Singer Harvey, Chou I-Ching, Grados Marco, Posthuma Danielle, Rouleau Guy A, Aschauer Harald, Freimer Nelson B, Pauls David L, Cox Nancy J, Mathews Carol A, Scharf Jeremiah M   Genetic association signal near NTN4 in Tourette syndrome Annals of neurology, 2014; 76(2): 310-5.

McGrath Lauren M, Yu Dongmei, Marshall Christian, Davis Lea K, Thiruvahindrapuram Bhooma, Li Bingbin, Cappi Carolina, Gerber Gloria, Wolf Aaron, Schroeder Frederick A, Osiecki Lisa, O’Dushlaine Colm, Kirby Andrew, Illmann Cornelia, Haddad Stephen, Gallagher Patience, Fagerness Jesen A, Barr Cathy L, Bellodi Laura, Benarroch Fortu, Bienvenu O Joseph, Black Donald W, Bloch Michael H, Bruun Ruth D, Budman Cathy L, Camarena Beatriz, Cath Danielle C, Cavallini Maria C, Chouinard Sylvain, Coric Vladimir, Cullen Bernadette, Delorme Richard, Denys Damiaan, Derks Eske M, Dion Yves, Rosário Maria C, Eapen Valsama, Evans Patrick, Falkai Peter, Fernandez Thomas V, Garrido Helena, Geller Daniel, Grabe Hans J, Grados Marco A, Greenberg Benjamin D, Gross-Tsur Varda, Grünblatt Edna, Heiman Gary A, Hemmings Sian M J, Herrera Luis D, Hounie Ana G, Jankovic Joseph, Kennedy James L, King Robert A, Kurlan Roger, Lanzagorta Nuria, Leboyer Marion, Leckman James F, Lennertz Leonhard, Lochner Christine, Lowe Thomas L, Lyon Gholson J, Macciardi Fabio, Maier Wolfgang, McCracken James T, McMahon William, Murphy Dennis L, Naarden Allan L, Neale Benjamin M, Nurmi Erika, Pakstis Andrew J, Pato Michele T, Pato Carlos N, Piacentini John, Pittenger Christopher, Pollak Yehuda, Reus Victor I, Richter Margaret A, Riddle Mark, Robertson Mary M, Rosenberg David, Rouleau Guy A, Ruhrmann Stephan, Sampaio Aline S, Samuels Jack, Sandor Paul, Sheppard Brooke, Singer Harvey S, Smit Jan H, Stein Dan J, Tischfield Jay A, Vallada Homero, Veenstra-VanderWeele Jeremy, Walitza Susanne, Wang Ying, Wendland Jens R, Shugart Yin Yao, Miguel Euripedes C, Nicolini Humberto, Oostra Ben A, Moessner Rainald, Wagner Michael, Ruiz-Linares Andres, Heutink Peter, Nestadt Gerald, Freimer Nelson, Petryshen Tracey, Posthuma Danielle, Jenike Michael A, Cox Nancy J, Hanna Gregory L, Brentani Helena, Scherer Stephen W, Arnold Paul D, Stewart S Evelyn, Mathews Carol A, Knowles James A, Cook Edwin H, Pauls David L, Wang Kai, Scharf Jeremiah M   Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study Journal of the American Academy of Child and Adolescent Psychiatry, 2014; 53(8): 910-9.

White Corey N, Congdon Eliza, Mumford Jeanette A, Karlsgodt Katherine H, Sabb Fred W, Freimer Nelson B, London Edythe D, Cannon Tyrone D, Bilder Robert M, Poldrack Russell A   Decomposing decision components in the stop-signal task: a model-based approach to individual differences in inhibitory control Journal of cognitive neuroscience, 2014; 26(8): 1601-14.

Lim Elaine T, Würtz Peter, Havulinna Aki S, Palta Priit, Tukiainen Taru, Rehnström Karola, Esko Tõnu, Mägi Reedik, Inouye Michael, Lappalainen Tuuli, Chan Yingleong, Salem Rany M, Lek Monkol, Flannick Jason, Sim Xueling, Manning Alisa, Ladenvall Claes, Bumpstead Suzannah, Hämäläinen Eija, Aalto Kristiina, Maksimow Mikael, Salmi Marko, Blankenberg Stefan, Ardissino Diego, Shah Svati, Horne Benjamin, McPherson Ruth, Hovingh Gerald K, Reilly Muredach P, Watkins Hugh, Goel Anuj, Farrall Martin, Girelli Domenico, Reiner Alex P, Stitziel Nathan O, Kathiresan Sekar, Gabriel Stacey, Barrett Jeffrey C, Lehtimäki Terho, Laakso Markku, Groop Leif, Kaprio Jaakko, Perola Markus, McCarthy Mark I, Boehnke Michael, Altshuler David M, Lindgren Cecilia M, Hirschhorn Joel N, Metspalu Andres, Freimer Nelson B, Zeller Tanja, Jalkanen Sirpa, Koskinen Seppo, Raitakari Olli, Durbin Richard, MacArthur Daniel G, Salomaa Veikko, Ripatti Samuli, Daly Mark J, Palotie Aarno, Palotie Aarno   Distribution and medical impact of loss-of-function variants in the Finnish founder population PLoS genetics, 2014; 10(7): e1004494.

Ma Dongzhu, Jasinska Anna J, Feyertag Felix, Wijewardana Viskam, Kristoff Jan, He Tianyu, Raehtz Kevin, Schmitt Christopher A, Jung Yoon, Cramer Jennifer Danzy, Dione Michel, Antonio Martin, Tracy Russell, Turner Trudy, Robertson David L, Pandrea Ivona, Freimer Nelson, Apetrei Cristian, Apetrei Cristian   Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild Journal of virology, 2014; 88(10): 5687-705.

Fears Scott C, Service Susan K, Kremeyer Barbara, Araya Carmen, Araya Xinia, Bejarano Julio, Ramirez Margarita, Castrillón Gabriel, Gomez-Franco Juliana, Lopez Maria C, Montoya Gabriel, Montoya Patricia, Aldana Ileana, Teshiba Terri M, Abaryan Zvart, Al-Sharif Noor B, Ericson Marissa, Jalbrzikowski Maria, Luykx Jurjen J, Navarro Linda, Tishler Todd A, Altshuler Lori, Bartzokis George, Escobar Javier, Glahn David C, Ospina-Duque Jorge, Risch Neil, Ruiz-Linares Andrés, Thompson Paul M, Cantor Rita M, Lopez-Jaramillo Carlos, Macaya Gabriel, Molina Julio, Reus Victor I, Sabatti Chiara, Freimer Nelson B, Bearden Carrie E   Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees JAMA psychiatry, 2014; 71(4): 375-87.

Service Susan K, Teslovich Tanya M, Fuchsberger Christian, Ramensky Vasily, Yajnik Pranav, Koboldt Daniel C, Larson David E, Zhang Qunyuan, Lin Ling, Welch Ryan, Ding Li, McLellan Michael D, O’Laughlin Michele, Fronick Catrina, Fulton Lucinda L, Magrini Vincent, Swift Amy, Elliott Paul, Jarvelin Marjo-Riitta, Kaakinen Marika, McCarthy Mark I, Peltonen Leena, Pouta Anneli, Bonnycastle Lori L, Collins Francis S, Narisu Narisu, Stringham Heather M, Tuomilehto Jaakko, Ripatti Samuli, Fulton Robert S, Sabatti Chiara, Wilson Richard K, Boehnke Michael, Freimer Nelson B   Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci PLoS genetics, 2014; 10(1): e1004147.

Davis Lea K, Yu Dongmei, Keenan Clare L, Gamazon Eric R, Konkashbaev Anuar I, Derks Eske M, Neale Benjamin M, Yang Jian, Lee S Hong, Evans Patrick, Barr Cathy L, Bellodi Laura, Benarroch Fortu, Berrio Gabriel Bedoya, Bienvenu Oscar J, Bloch Michael H, Blom Rianne M, Bruun Ruth D, Budman Cathy L, Camarena Beatriz, Campbell Desmond, Cappi Carolina, Cardona Silgado Julio C, Cath Danielle C, Cavallini Maria C, Chavira Denise A, Chouinard Sylvain, Conti David V, Cook Edwin H, Coric Vladimir, Cullen Bernadette A, Deforce Dieter, Delorme Richard, Dion Yves, Edlund Christopher K, Egberts Karin, Falkai Peter, Fernandez Thomas V, Gallagher Patience J, Garrido Helena, Geller Daniel, Girard Simon L, Grabe Hans J, Grados Marco A, Greenberg Benjamin D, Gross-Tsur Varda, Haddad Stephen, Heiman Gary A, Hemmings Sian M J, Hounie Ana G, Illmann Cornelia, Jankovic Joseph, Jenike Michael A, Kennedy James L, King Robert A, Kremeyer Barbara, Kurlan Roger, Lanzagorta Nuria, Leboyer Marion, Leckman James F, Lennertz Leonhard, Liu Chunyu, Lochner Christine, Lowe Thomas L, Macciardi Fabio, McCracken James T, McGrath Lauren M, Mesa Restrepo Sandra C, Moessner Rainald, Morgan Jubel, Muller Heike, Murphy Dennis L, Naarden Allan L, Ochoa William Cornejo, Ophoff Roel A, Osiecki Lisa, Pakstis Andrew J, Pato Michele T, Pato Carlos N, Piacentini John, Pittenger Christopher, Pollak Yehuda, Rauch Scott L, Renner Tobias J, Reus Victor I, Richter Margaret A, Riddle Mark A, Robertson Mary M, Romero Roxana, Rosàrio Maria C, Rosenberg David, Rouleau Guy A, Ruhrmann Stephan, Ruiz-Linares Andres, Sampaio Aline S, Samuels Jack, Sandor Paul, Sheppard Brooke, Singer Harvey S, Smit Jan H, Stein Dan J, Strengman E, Tischfield Jay A, Valencia Duarte Ana V, Vallada Homero, Van Nieuwerburgh Filip, Veenstra-Vanderweele Jeremy, Walitza Susanne, Wang Ying, Wendland Jens R, Westenberg Herman G M, Shugart Yin Yao, Miguel Euripedes C, McMahon William, Wagner Michael, Nicolini Humberto, Posthuma Danielle, Hanna Gregory L, Heutink Peter, Denys Damiaan, Arnold Paul D, Oostra Ben A, Nestadt Gerald, Freimer Nelson B, Pauls David L, Wray Naomi R, Stewart S Evelyn, Mathews Carol A, Knowles James A, Cox Nancy J, Scharf Jeremiah M   Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture PLoS genetics, 2013; 9(10): e1003864.

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