Posts classified under: S

Yi Sun, Ph.D.

Publications

A selected list of publications:

Zeng Yan, Tan Miao, Kohyama Jun, Sneddon Marissa, Watson Joseph B, Sun Yi E, Xie Cui-Wei   Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(49): 17800-10.
Tao Jifang, Wu Hao, Lin Quan, Wei Weizheng, Lu Xiao-Hong, Cantle Jeffrey P, Ao Yan, Olsen Richard W, Yang X William, Mody Istvan, Sofroniew Michael V, Sun Yi E   Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(22): 8306-19.
Wilburn Brian, Rudnicki Dobrila D, Zhao Jing, Weitz Tara Murphy, Cheng Yin, Gu Xiaofeng, Greiner Erin, Park Chang Sin, Wang Nan, Sopher Bryce L, La Spada Albert R, Osmand Alex, Margolis Russell L, Sun Yi E, Yang X William   An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington’s disease-like 2 mice Neuron, 2011; 70(3): 427-40.
Wu Hao, D’Alessio Ana C, Ito Shinsuke, Xia Kai, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi   Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells Nature, 2011; 473(7347): 389-93.
Wu Hao, D’Alessio Ana C, Ito Shinsuke, Wang Zhibin, Cui Kairong, Zhao Keji, Sun Yi Eve, Zhang Yi   Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells Genes & development, 2011; 25(7): 679-84.
Ge, W He, F Kim, KJ Blanchi, B Coskun, V Nguyen, L Wu, X Zhao, J Heng, JI Martinowich, K Tao, J Wu, H Castro, D Sobeih, MM Corfas, G Gleeson, JG Greenberg, ME Guillemot, F Sun, YE   Coupling of cell migration with neurogenesis by proneural bHLH factors PNAS, 2006; 103(5): 1319-1324.
Damelin, M Sun, YE Sodja, VB Bestor, TH   Decatenation checkpoint deficiency in stem and progenitor cells Cancer cell, 2005; 8(6): 479-84.
Ladi, E Nichols, JT Ge, W Miyamoto, A Yao, C Yang, LT Boulter, J Sun, YE Kintner, C Weinmaster, G   The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands The Journal of cell biology. , 2005; 170(6): 983-92.
Fan, G Martinowich, K Chin, MH He, F Fouse, SD Hutnick, L Hattori, D Ge, W Shen, Y Wu, H ten Hoeve, J Shuai, K Sun, YE   DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling Development (Cambridge, England) , 2005; 132(15): 3345-56.
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He, F Ge, W Martinowich, K Becker-Catania, S Coskun, V Zhu, W Wu, H Castro, D Guillemot, F Fan, G de Vellis, J Sun, YE   A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis Nature neuroscience. , 2005; 8(5): 616-25.
Martin, KC Sun, YE   To learn better, keep the HAT on Neuron. , 2004; 42(6): 879-81.
Martinowich, K Hattori, D Wu, H Fouse, S He, F Hu, Y Fan, G Sun, YE   DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation Science. , 2003; 302(5646): 890-3.
Sun, Y Nadal-Vicens, M Misono, S Lin, MZ Zubiaga, A Hua, X Fan, G Greenberg, ME   Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms Cell. , 2001; 104(3): 365-76.
Fan G, Egles C, Sun Y, Minichiello L, Renger J, Klein R, Liu G, Jaenisch R   NT4 and BDNF have Overlapping as well as Distinct Function in vivo, Nature Neuroscience, 2000; 3: 350-357.
Gao, Y Sun, Y Frank, KM Dikkes, P Fujiwara, Y Seidl, KJ Sekiguchi, JM Rathbun, GA Swat, W Wang, J Bronson, RT Malynn, BA Bryans, M Zhu, C Chaudhuri, J Davidson, L Ferrini, R Stamato, T Orkin, SH Greenberg, ME Alt, FW   A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis Cell. , 1998; 95(7): 891-902.
Bonni A*, Sun Y*(equal first authorship), Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME   Regulation of CNS Gliogenesis by JAK-STAT Signaling Pathway, Science, 1997; 278: 477-483.
Rao MS, Sun Y, Escary JL, Perreau J, Tresser S, Patterson PH, Zigmond RE, Brulet P, Landis SC   Leukemia Inhibitory Factor Mediates an Injury Response but not a target-directed developmental transmitter switch in sympathetic neurons, Neuron, 1993; 11: 1175-1185.

Igor Spigelman, Ph.D.

Publications

A selected list of publications:

Shen Yi, Lindemeyer A Kerstin, Spigelman Igor, Sieghart Werner, Olsen Richard W, Liang Jing   Plasticity of GABAA receptors after ethanol pre-exposure in cultured hippocampal neurons Molecular pharmacology, 2011; 79(3): 432-42.
Ruangsri Supanigar, Lin Audrey, Mulpuri Yatendra, Lee Kyung, Spigelman Igor, Nishimura Ichiro   RELATIONSHIP OF AXONAL VOLTAGE-GATED SODIUM CHANNEL 1.8 (NaV1.8) mRNA ACCUMULATION TO SCIATIC NERVE INJURY-INDUCED PAINFUL NEUROPATHY IN RATS The Journal of biological chemistry, 2011; .
Suryanarayanan Asha, Liang Jing, Meyer Edward M, Lindemeyer A Kerstin, Chandra Dev, Homanics Gregg E, Sieghart Werner, Olsen Richard W, Spigelman Igor   Subunit Compensation and Plasticity of Synaptic GABA(A) Receptors Induced by Ethanol in ?4 Subunit Knockout Mice Frontiers in neuroscience, 2011; 5(3): 110.
Díaz-Cintra Sofia, Xue Baogang, Spigelman Igor, Van K, Wong Alan M, Obenaus Andre, Ribak Charles E   Dentate granule cells form hilar basal dendrites in a rat model of hypoxia-ischemia Brain research, 2009; 1285: 182-7.
Thakor Devang Kashyap, Lin Audrey, Matsuka Yoshizo, Meyer Edward M, Ruangsri Supanigar, Nishimura Ichiro, Spigelman Igor   Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy Molecular pain, 2009; 5(1): 14.
Ribak Charles E, Shapiro Lee A, Perez Zachary D, Spigelman Igor   Microglia-associated granule cell death in the normal adult dentate gyrus Brain structure & function, 2009; .
Matsuka Yoshizo, Ono Takeshi, Iwase Hirotate, Mitrirattanakul Somsak, Omoto Kevin S, Cho Ting, Lam Yan Yan N, Snyder Bradley, Spigelman Igor   Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats Molecular pain, 2008; 4(1): 66.
Jain Naveen K, Ishikawa Tomo-o, Spigelman Igor, Herschman Harvey R   COX-2 expression and function in the hyperalgesic response to paw inflammation in mice Prostaglandins, leukotrienes, and essential fatty acids, 2008; 79(6): 183-90.
Liang Jing, Suryanarayanan Asha, Chandra Dev, Homanics Gregg E, Olsen Richard W, Spigelman Igor   Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells Alcoholism, clinical and experimental research, 2008; 32(1): 19-26.
Chandra Dev, Werner David F, Liang Jing, Suryanarayanan Asha, Harrison Neil L, Spigelman Igor, Olsen Richard W, Homanics Gregg E   Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice Alcoholism, clinical and experimental research, 2008; 32(1): 10-8.
Mitrirattanakul Somsak, López-Valdés Héctor E, Liang Jing, Matsuka Yoshizo, Mackie Ken, Faull Kym F, Spigelman Igor   Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence Alcoholism, clinical and experimental research, 2007; 31(5): 855-67.
Liang Jing, Suryanarayanan Asha, Abriam Alana, Snyder Bradley, Olsen Richard W, Spigelman Igor   Mechanisms of reversible GABAA receptor plasticity after ethanol intoxication The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007; 27(45): 12367-77.
Thakor Devang, Spigelman Igor, Tabata Yasuhiko, Nishimura Ichiro   Subcutaneous peripheral injection of cationized gelatin/DNA polyplexes as a platform for non-viral gene transfer to sensory neurons Molecular therapy : the journal of the American Society of Gene Therapy, 2007; 15(12): 2124-31.
Liang, J., Zhang, N., Cagetti, E. Houser, C.R., Olsen, R.W. and Spigelman, I.   Chronic intermittent ethanol treatment-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors, Journal of Neuroscience, 2006; 26: 1749-1758.
Liang Jing, Zhang Nianhui, Cagetti Elisabetta, Houser Carolyn R, Olsen Richard W, Spigelman Igor   Chronic intermittent ethanol-induced switch of ethanol actions from extrasynaptic to synaptic hippocampal GABAA receptors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(6): 1749-58.
Chandra, D., Jia, F., Liang, J., Peng, Z., Suryanarayanan, A., Werner, D.F., Spigelman, I., Houser, C.R., Olsen, R.W., Harrison, N.L. and Homanics, G.E.   GABA(A) receptor alpha4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol, Proceedings of the National Academy of Sciences USA, 2006; 103: 15230-15235.
Spigelman, I.   Physiologic mechanisms of inhibition and status epilepticus, In: Status Epilepticus, Mechanisms and Management, C.G. Wasterlain and D.M. Treiman editors, MIT Press, Cambridge,, 2006; Chapter 21: 281-293.
Mitrirattanakul Somsak, Ramakul Navapoln, Guerrero Andre V, Matsuka Yoshizo, Ono Takeshi, Iwase Hirotate, Mackie Ken, Faull Kym F, Spigelman Igor   Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain Pain, 2006; 126(1-3): 102-14.
Olsen, R.W., Liang, J., Cagetti, E., and Spigelman, I.   Plasticity of GABAA receptors in brains of rats treated with chronic intermittent ethanol , Neurochemical Research, 2005; 30: 1579-1588.
Matsuka Y. and Spigelman, I.   Hyperosmolar solutions selectively block action potentials in rat myelinated sensory fibers: implications for diabetic neuropathy, Journal of Neurophysiology, 2004; 91: 48-56.
Matsuka, Y Neubert, JK Maidment, NT Spigelman, I   Concurrent release of ATP and substance P within guinea pig trigeminal ganglia in vivo Brain research. , 2001; 915(2): 248-55.
Spigelman, I., Gold, M.S., Light A.R.   Electrophysiological Methods in Pain Research, Methods in Pain Research, 2001; Chapter 8: 147-168.
Spigelman, I., Neubert, J.K., Matsuka, Y., Maidment, N.T.   Extracellular Sampling, Methods in Pain Research, 2001; Chapter 7: 133-146.
Neubert, JK Maidment, NT Matsuka, Y Adelson, DW Kruger, L Spigelman, I   Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo Brain research. , 2000; 871(2): 181-91.
Spigelman, I Yan, XX Obenaus, A Lee, EY Wasterlain, CG Ribak, CE   Dentate granule cells form novel basal dendrites in a rat model of temporal lobe epilepsy Neuroscience. , 1998; 86(1): 109-20.
Spigelman, I Obenaus, A Mazarati, A Wasterlain, CG   Intravenously administered cell-permeant calcium buffer decreases evoked synaptic potentials in rat dentate gyrus in vivo Brain research. , 1998; 810(1-2): 269-73.

Desmond Smith, M.D., Ph.D.

Biography

Desmond Smith’s first degree was in Physics from Oxford University, England. He went on to obtain a PhD from Cambridge University in Molecular Biology and a medical degree from Oxford University. After postgraduate medical training in the UK, Dr Smith went to Harvard University to do a postdoctoral fellowship in Drosophila genetics and another postdoc at Lawrence Berkeley National Laboratory in mouse genetics. Dr Smith is currently a Professor at the Department of Molecular and Medical Pharmacology at UCLA.