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James Waschek, Ph.D.

Faculty Member

Professor
Department of Psychiatry & Biobehavioral Sciences
David Geffen School of Medicine
University of California, Los Angeles

 

Neuroscience Research Building, Room 355
635 Charles E. Young Dr. South
Los Angeles, CA 90095

 

Biography

Dr. Waschek is a Professor of Psychiatry and Biobehavioral Science at the David Geffen School of Medicine at the University of California at Los Angeles (UCLA), and is an expert in the molecular and cellular biology and physiological actions of neuropeptides. Dr. Waschek received a Ph.D. in Pharmaceutical Chemistry in 1984 from the University of California at San Francisco, after which he took a postdoctoral position at the National Institutes of Health (NIH). In 1988 he came to UCLA, where his research has centered on three broad, but related topics: 1) CNS development, degeneration, injury, and repair, 2) neuroinflammatory conditions such as multiple sclerosis, and maternal inflammation-induced perinatal white matter disease, and 3) brain tumor pathogenesis. A past and continuing objective has been to better understand the biological roles of neuropeptides in these processes, especially the two related peptides PACAP and VIP (pituitary adenylyl cyclase activating peptide and vasoactive intestinal peptide, respectively). A major contribution in this area was his discovery first reported in 1998 that PACAP and functional PACAP receptors are highly expressed in the murine neural tube and other germinal centers, and that PACAP acts in part via cAMP and protein kinase A to regulate neural patterning and proliferation via antagonism of hedgehog signaling. Using gene targeting and other approaches, he found this interaction to be relevant not only during brain development, but also in the pathogenesis of malignant pediatric brain tumors. In other work, he has demonstrated growth factor-like actions of PACAP in the maturation of white matter (myelin) and in axon regeneration after injury. Most recently, he determined that VIP and PACAP are critically involved in inflammatory responses after nerve injury and in other pathologies such as lung and liver injury, colitis, cystitis, viral infection, and in an animal model of multiple sclerosis. These studies have revealed significant effects of PACAP and VIP PACAP loss on innate cellular responses to injury, as well as in Th1, Th2, and Th17 differentiation, regulatory T cell production, and immune cell invasion of the CNS parenchyma. Has been continuously funding for his research by the NIH since 1984, and is also currently receiving funding through major grants from the National Institutes of Health, the National Multiple Sclerosis Society, the Department of Defense, and the Simons Foundation. Dr. Waschek has served on NIH study sections almost continuously since 2006, and served as an external reviewer for the newly-formed LOWEE Institute on Tumors and Inflammation in Marburg, Germany, and a consultant for the Japanese-Israeli Scientific and Technological Cooperation Agreement in Life Sciences in the Topic of Stem Cell Research.

 

Publications

A selected list of publications:

Tan Yossan-Var, Abad Catalina, Wang Yuqi, Lopez Robert, Waschek James A   Pituitary Adenylate Cyclase Activating Peptide Deficient Mice Exhibit Impaired Thymic and Extrathymic Regulatory T Cell Proliferation during EAE PloS one, 2013; 8(4): e61200.

Yan Yan, Zhou Xiaofeng, Pan Zui, Ma Jianjie, Waschek James A, DiCicco-Bloom Emanuel   Pro- and anti-mitogenic actions of pituitary adenylate cyclase-activating polypeptide in developing cerebral cortex: potential mediation by developmental switch of PAC1 receptor mRNA isoforms The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(9): 3865-78.
Tyagi Ethika, Agrawal Rahul, Zhuang Yumei, Abad Catalina, Waschek James A, Gomez-Pinilla Fernando   Vulnerability imposed by diet and brain trauma for anxiety-like phenotype: implications for post-traumatic stress disorders PloS one, 2013; 8(3): e57945.
Ji Haofeng, Zhang Yu, Shen Xiuda, Gao Feng, Huang Cynthia Y, Abad Catalina, Busuttil Ronald W, Waschek James A, Kupiec-Weglinski Jerzy W   Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation via cAMP-PKA pathway Hepatology (Baltimore, Md.), 2012; 166(1): .
Nobuta Hiroko, Ghiani Cristina A, Paez Pablo M, Spreuer Vilma, Dong Hongmei, Korsak Rose A, Manukyan Armine, Li Jiaxi, Vinters Harry V, Huang Eric J, Rowitch David H, Sofroniew Michael V, Campagnoni Anthony T, de Vellis Jean, Waschek James A   STAT3-mediated astrogliosis protects myelin development in neonatal brain injury Annals of neurology, 2012; 72(5): 750-65.
Abad Catalina, Tan Yossan-Var, Cheung-Lau Gardenia, Nobuta Hiroko, Waschek James A   VIP deficient mice exhibit resistance to lipopolysaccharide induced endotoxemia with an intrinsic defect in proinflammatory cellular responses PloS one, 2012; 7(5): e36922.
Abad Catalina, Gomariz Rosa, Waschek James, Leceta Javier, Martinez Carmen, Juarranz Yasmina, Arranz Alicia   VIP in inflammatory bowel disease: state of the art Endocrine, metabolic & immune disorders drug targets, 2012; 12(4): 316-22.
Ghiani Cristina A, Mattan Natalia S, Nobuta Hiroko, Malvar Jemily S, Boles Julie, Ross Michael G, Waschek James A, Carpenter Ellen M, Fisher Robin S, de Vellis Jean   Early effects of lipopolysaccharide-induced inflammation on foetal brain development in rat ASN neuro, 2011; 3(4): .
Loh Dawn H, Dragich Joanna M, Kudo Takashi, Schroeder Analyne M, Nakamura Takahiro J, Waschek James A, Block Gene D, Colwell Christopher S   Effects of vasoactive intestinal Peptide genotype on circadian gene expression in the suprachiasmatic nucleus and peripheral organs Journal of biological rhythms, 2011; 26(3): 200-9.
Alexandre David, Alonzeau Jessy, Bill Brent R, Ekker Stephen C, Waschek James A   Expression analysis of PAC1-R and PACAP genes in zebrafish embryos Journal of molecular neuroscience : MN, 2011; 43(1): 94-100.
Abad Catalina, Waschek James A   Immunomodulatory roles of VIP and PACAP in models of multiple sclerosis Current pharmaceutical design, 2011; 17(10): 1025-35.
Hirose Megumi, Niewiadomski Pawel, Tse Gary, Chi Gloria C, Dong Hongmei, Lee Alice, Carpenter Ellen M, Waschek James A   Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures Journal of neuroscience research, 2011; 89(9): 1363-74.
Tan Yossan-Var, Waschek James A   Targeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis ASN neuro, 2011; 3(4): .
Dragich Joanna M, Loh Dawn H, Wang Louisa M, Vosko Andrew M, Kudo Takashi, Nakamura Takahiro J, Odom Irene H, Tateyama Sei, Hagopian Arkady, Waschek James A, Colwell Christopher S   The role of the neuropeptides PACAP and VIP in the photic regulation of gene expression in the suprachiasmatic nucleus The European journal of neuroscience, 2010; 31(5): 864-75.
Abad Catalina, Tan Yossan-Var, Lopez Robert, Nobuta Hiroko, Dong Hongmei, Phan Phu, Feng Ji-Ming, Campagnoni Anthony T, Waschek James A   Vasoactive intestinal peptide loss leads to impaired CNS parenchymal T-cell infiltration and resistance to experimental autoimmune encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(45): 19555-60.
Kim Woo-Kyun, Meliton Vicente, Park Kye Won, Hong Cynthia, Tontonoz Peter, Niewiadomski Pawel, Waschek James A, Tetradis Sotirios, Parhami Farhad   Negative regulation of Hedgehog signaling by liver X receptors Molecular endocrinology (Baltimore, Md.), 2009; 23(10): 1532-43.
Tan Yossan-Var, Abad Catalina, Lopez Robert, Dong Hongmei, Liu Shen, Lee Alice, Gomariz Rosa P, Leceta Javier, Waschek James A   Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis Proceedings of the National Academy of Sciences of the United States of America, 2009; 106(6): 2012-7.
Stack Conor M, Lim Maria A, Cuasay Katrina, Stone Madeleine M, Seibert Kimberly M, Spivak-Pohis Irit, Crawley Jacqueline N, Waschek James A, Hill Joanna M   Deficits in social behavior and reversal learning are more prevalent in male offspring of VIP deficient female mice Experimental neurology, 2008; 211(1): 67-84.
Lelievre Vincent, Seksenyan Akop, Nobuta Hiroko, Yong William H, Chhith Seririthanar, Niewiadomski Pawel, Cohen Joseph R, Dong Hongmei, Flores Avegail, Liau Linda M, Kornblum Harley I, Scott Matthew P, Waschek James A   Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice Developmental biology, 2008; 313(1): 359-70.
Armstrong B D, Abad C, Chhith S, Cheung-Lau G, Hajji O E, Nobuta H, Waschek J A   Impaired nerve regeneration and enhanced neuroinflammatory response in mice lacking pituitary adenylyl cyclase activating peptide Neuroscience, 2008; 151(1): 63-73.
Nemetz Nicole, Abad Catalina, Lawson Greg, Nobuta Hiroko, Chhith Seririthanar, Duong Lucy, Tse Gary, Braun Jonathan, Waschek James A   Induction of colitis and rapid development of colorectal tumors in mice deficient in the neuropeptide PACAP International journal of cancer. Journal international du cancer, 2008; 122(8): 1803-9.
Niewiadomski Pawel, Coûté-Monvoisin Anne-Claire, Abad Catalina, Ngo Danny, Menezes Adrian, Waschek James A   Mice Deficient in both Pituitary Adenylyl Cyclase-activating Polypeptide and Vasoactive Intestinal Peptide Survive, but Display Growth Retardation and Sex-dependent Early Death Journal of molecular neuroscience : MN, 2008; 36(1-3): 200-7.
Lim Maria A, Stack Conor M, Cuasay Katrina, Stone Madeleine M, McFarlane Hewlet G, Waschek James A, Hill Joanna M   Regardless of genotype, offspring of VIP-deficient female mice exhibit developmental delays and deficits in social behavior International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2008; 26(5): 423-34.
Studeny Simon, Cheppudira Bopaiah P, Meyers Susan, Balestreire Elena M, Apodaca Gerard, Birder Lori A, Braas Karen M, Waschek James A, May Victor, Vizzard Margaret A   Urinary bladder function and somatic sensitivity in vasoactive intestinal polypeptide (VIP)-/- mice Journal of molecular neuroscience : MN, 2008; 36(1-3): 175-87.
Loh Dawn H, Abad Catalina, Colwell Christopher S, Waschek James A   Vasoactive intestinal peptide is critical for circadian regulation of glucocorticoids Neuroendocrinology, 2008; 88(4): 246-55.
Lacombe Arnaud, Lelievre Vincent, Roselli Charles E, Muller Jean-Marc, Waschek James A, Vilain Eric   Lack of vasoactive intestinal peptide reduces testosterone levels and reproductive aging in mouse testis The Journal of endocrinology, 2007; 194(1): 153-60.
Lacombe Arnaud, Lelievre Vincent, Roselli Charles E, Salameh Wael, Lue Yan-he, Lawson Gregory, Muller Jean-Marc, Waschek James A, Vilain Eric   Delayed testicular aging in pituitary adenylate cyclase-activating peptide (PACAP) null mice Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(10): 3793-8.
Aton Sara J, Colwell Christopher S, Harmar Anthony J, Waschek James, Herzog Erik D   Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons Nature neuroscience, 2005; 8(4): 476-83.
Colwell Christopher S, Michel Stephan, Itri Jason, Rodriguez Williams, Tam J, Lelievre Vincent, Hu Zhou, Liu X, Waschek James A   Disrupted circadian rhythms in VIP- and PHI-deficient mice American journal of physiology. Regulatory, integrative and comparative physiology, 2003; 285(5): R939-49.
Nicot Arnaud, Lelièvre Vincent, Tam Jimmy, Waschek James A, DiCicco-Bloom Emanuel   Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002; 22(21): 9244-54.
Niewiadomski Pawel, Zhujiang Annie, Youssef Mary, Waschek James A   Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA Cellular signalling, 2013; 25(11): 2222-30.
Li Jian-Ming, Southerland Lauren, Hossain Mohammad S, Giver Cynthia R, Wang Ying, Darlak Kasia, Harris Wayne, Waschek James, Waller Edmund K   Absence of vasoactive intestinal peptide expression in hematopoietic cells enhances Th1 polarization and antiviral immunity in mice Journal of immunology (Baltimore, Md. : 1950), 2011; 187(2): 1057-65.
Ji Haofeng, Zhang Yu, Liu Yuanxing, Shen Xiu-Da, Gao Feng, Nguyen Terry T, Busuttil Ronald W, Waschek James A, Kupiec-Weglinski Jerzy W   Vasoactive intestinal peptide attenuates liver ischemia/reperfusion injury in mice via the cyclic adenosine monophosphate-protein kinase a pathway Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013; 19(9): 945-56.
Abad Catalina, Nobuta Hiroko, Li Jiaxi, Kasai Atsushi, Yong William H, Waschek James A   Targeted STAT3 disruption in myeloid cells alters immunosuppressor cell abundance in a murine model of spontaneous medulloblastoma Journal of leukocyte biology, 2014; 95(2): 357-67.
Marquez Paul, Bebawy David, Lelièvre Vincent, Coûté Anne-Claire, Evans Christopher J, Waschek James A, Lutfy Kabirullah   The role of endogenous PACAP in motor stimulation and conditioned place preference induced by morphine in mice Psychopharmacology, 2009; 204(3): 457-63.
Kim Kyun-Do, Srikanth Sonal, Tan Yossan-Var, Yee Ma-Khin, Jew Marcus, Damoiseaux Robert, Jung Michael E, Shimizu Saki, An Dong Sung, Ribalet Bernard, Waschek James A, Gwack Yousang   Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation Journal of immunology (Baltimore, Md. : 1950), 2014; 192(1): 110-22.
Vu John P, Million Mulugeta, Larauche Muriel, Luong Leon, Norris Joshua, Waschek James A, Pothoulakis Charalabos, Pisegna Joseph R, Germano Patrizia M   Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice Journal of molecular neuroscience : MN, 2014; 52(1): 37-47.
Brown T M, Colwell C S, Waschek J A, Piggins H D   Disrupted neuronal activity rhythms in the suprachiasmatic nuclei of vasoactive intestinal polypeptide-deficient mice Journal of neurophysiology, 2007; 97(3): 2553-8.
Watson M B, Nobuta H, Abad C, Lee S K, Bala N, Zhu C, Richter F, Chesselet M-F, Waschek J A   PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in mice Neuroscience, 2013; 240: 277-86.
Waschek J A   VIP and PACAP: neuropeptide modulators of CNS inflammation, injury, and repair British journal of pharmacology, 2013; 169(3): 512-23.
Colwell C S, Michel S, Itri J, Rodriguez W, Tam J, Lelièvre V, Hu Z, Waschek J A   Selective deficits in the circadian light response in mice lacking PACAP American journal of physiology. Regulatory, integrative and comparative physiology, 2004; 287(5): R1194-201.
Vu John P, Larauche Muriel, Flores Martin, Luong Leon, Norris Joshua, Oh Suwan, Liang Li-Jung, Waschek James, Pisegna Joseph R, Germano Patrizia M   Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP) Journal of molecular neuroscience : MN, 2015; 56(2): 377-87.
Ago Yukio, Condro Michael C, Tan Yossan-Var, Ghiani Cristina A, Colwell Christopher S, Cushman Jesse D, Fanselow Michael S, Hashimoto Hitoshi, Waschek James A   Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist Psychopharmacology, 2015; 232(12): 2181-9.
Onaka Yusuke, Shintani Norihito, Nakazawa Takanobu, Haba Ryota, Ago Yukio, Wang Hyper, Kanoh Takuya, Hayata-Takano Atsuko, Hirai Hiroyuki, Nagata Kin-Ya, Nakamura Masataka, Hashimoto Ryota, Matsuda Toshio, Waschek James A, Kasai Atsushi, Nagayasu Kazuki, Baba Akemichi, Hashimoto Hitoshi   CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice Behavioural brain research, 2015; 284(12): 131-7.
Tan Yossan-Var, Abad Catalina, Wang Yuqi, Lopez Robert, Waschek James A   VPAC2 (vasoactive intestinal peptide receptor type 2) receptor deficient mice develop exacerbated experimental autoimmune encephalomyelitis with increased Th1/Th17 and reduced Th2/Treg responses Brain, behavior, and immunity, 2015; 44(12): 167-75.
Yamasaki Atsushi, Kasai Atsushi, Toi Akihiro, Kurita Maki, Kimoto Saki, Hayata-Takano Atsuko, Nakazawa Takanobu, Nagayasu Kazuki, Shintani Norihito, Hashimoto Ryota, Ito Akira, Meltzer Herbert Y, Ago Yukio, Waschek James A, Onaka Yusuke, Matsuda Toshio, Baba Akemichi, Hashimoto Hitoshi   Identification of the role of bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro Journal of neurochemistry, 2015; 132(4): 418-28.
Abad Catalina, Cheung-Lau Gardenia, Coûté-Monvoisin Anne-Claire, Waschek James A   Vasoactive intestinal peptide-deficient mice exhibit reduced pathology in trinitrobenzene sulfonic acid-induced colitis Neuroimmunomodulation, 2015; 22(3): 203-12.
Wu Xiujuan, Conlin Victoria S, Morampudi Vijay, Ryz Natasha R, Nasser Yasmin, Bhinder Ganive, Bergstrom Kirk S, Yu Hong B, Waterhouse Chris C M, Buchan Allison M J, Popescu Oana E, Gibson William T, Waschek James A, Vallance Bruce A, Jacobson Kevan   Vasoactive intestinal polypeptide promotes intestinal barrier homeostasis and protection against colitis in mice PloS one, 2015; 10(5): e0125225.
Castorina Alessandro, Waschek James A, Marzagalli Rubina, Cardile Venera, Drago Filippo   PACAP interacts with PAC1 receptors to induce tissue plasminogen activator (tPA) expression and activity in schwann cell-like cultures PloS one, 2015; 10(2): e0117799.
Teuchner Barbara, Dimmer Andreas, Humpel Christian, Amberger Albert, Fischer-Colbrie Reiner, Nemeth Jozsef, Waschek James A, Kieselbach Gerhard, Kralinger Martina, Schmid Eduard, Bechrakis Nikolaos, Troger Josef   VIP, PACAP-38, BDNF and ADNP in NMDA-induced excitotoxicity in the rat retina Acta ophthalmologica, 2011; 89(7): 670-5.
Cohen Joseph R, Resnick Daniel Z, Niewiadomski Pawel, Dong Hongmei, Liau Linda M, Waschek James A   Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures BMC cancer, 2010; 10(7): 676.
Martin Bronwen, Shin Yu-Kyong, White Caitlin M, Ji Sunggoan, Kim Wook, Carlson Olga D, Napora Joshua K, Chadwick Wayne, Chapter Megan, Waschek James A, Mattson Mark P, Maudsley Stuart, Egan Josephine M   Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression Diabetes, 2010; 59(5): 1143-52.
Girard Beatrice M, Malley Susan E, Braas Karen M, Waschek James A, May Victor, Vizzard Margaret A   Exaggerated expression of inflammatory mediators in vasoactive intestinal polypeptide knockout (VIP-/-) mice with cyclophosphamide (CYP)-induced cystitis Journal of molecular neuroscience : MN, 2008; 36(1-3): 188-99.
Nakano Ichiro, Masterman-Smith Michael, Saigusa Kuniyasu, Paucar Andres A, Horvath Steve, Shoemaker Lorelei, Watanabe Momoko, Negro Alejandra, Bajpai Ruchi, Howes Amy, Lelievre Vincent, Waschek James A, Lazareff Jorge A, Freije William A, Liau Linda M, Gilbertson Richard J, Cloughesy Timothy F, Geschwind Daniel H, Nelson Stanley F, Mischel Paul S, Terskikh Alexey V, Kornblum Harley I   Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells Journal of neuroscience research, 2008; 86(1): 48-60.

Benjamin Wu, D.D.S., Ph.D.

Faculty Member

Professor Emeritus
Department of Bioengineering
Department of Dentistry
University of California, Los Angeles

 

Department of Bioengineering
Engineering V, Room 5121 K
Los Angeles, CA 90095

UCLA School of Dentistry
10833 Le Conte Ave
Los Angeles, CA 90095-1668

 

Biography

Prof. Ben Wu received his D.D.S. from the University of Pacific, his advanced prosthodontics specialty certificate at the Harvard School of Dental Medicine, and his Ph.D. in Materials Science and Engineering from the Massachusetts Institute of Technology. He is currently Professor and Chair of the UCLA Department of Bioengineering, and Chair of the Division of Advanced Prosthodontics in the School of Dentistry. He holds joint appointment in the Department of Materials Science and Engineering, and in the Department of Orthopedic Surgery in the School of Medicine. Prof. Wu is Director of the Weintraub Center for Reconstructive Biotechnology, and a member of the UCLA Brain Research Institute, the California NanoSystems Institute, and Fellow of the the Academy of Prosthodontics.

 

Publications

A selected list of publications:

Lee M, Siu RK, Ting K, Wu BM   Effect of nell-1 delivery on chondrocyte proliferation and cartilaginous extracellular matrix deposition Tissue Eng Part A, 2010; 16(5): 1791-800.

Yuki I, Uchiyama N, Murayama Y, Nien YL, Lee D, Ebara M, Ishii A, Chiang A, Vinters HV, Nishimura I, Wu BM, Vinuela F   Intravascular tissue reactions induced by various types of bioabsorbable polymeric materials: correlation between the degradation profiles and corresponding tissue reactions Neuroradiology, 2010; 52(11): 1017-24.
Pham EA, Ho WJ, Kamei DT, Wu BM   Modification of the diphenylamine assay for cell quantification in three-dimensional biodegradable polymeric scaffolds J Biomed Mater Res B Appl Biomater, 2010; 92(2): 499-507.
Aghaloo T, Cowan CM, Zhang X, Freymiller E, Soo C, Wu B, Ting K, Zhang Z   The effect of NELL1 and bone morphogenetic protein-2 on calvarial bone regeneration J Oral Maxillofac Surg, 2010; 68(2): 300-8.
Lee M, Li W, Siu RK, Whang J, Zhang X, Soo C, Ting K, Wu BM.   Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers Biomaterials, 2009; 30(30): 6094-101.
Choi CH, Heydarkhan-Hagvall S, Wu BM, Dunn JC, Beygui RE, Kim CJ.   Cell growth as a sheet on three-dimensional sharp-tip nanostructures J Biomed Mater Res A, 2009; 89(3): 804-17.
Kramerova I, Kudryashova E, Wu B, Germain S, Vandenborne K, Romain N, Haller RG, Verity MA, Spencer MJ.   Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle Hum Mol Genet, 2009; 18(17): 3194-205.
Lee, M. Wu, B. M. Dunn, J. C. Y.   Effect of scaffold architecture and pore size on smooth muscle cell growth Journal of Biomedical Materials Research Part A, 2008; 87A(4): 1010-1016.
Brown, D. A. MacLellan, W. R. Dunn, J. C. Y. Wu, B. M. Beygui, R. E.   Hypoxic cell death is reduced by pH buffering in a model of engineered heart tissue Artificial Cells Blood Substitutes and Biotechnology, 2008; 36(2): 94-113.
Lee, M. Wu, B. M. Stelzner, M. Reichardt, H. M. Dunn, J. C. Y.   Intestinal smooth muscle cell maintenance by basic fibroblast growth factor Tissue Engineering Part A, 2008; 14(8): 1395-1402.
Lee M, Wu BM, Stelzner M, Reichardt HM, Dunn JC.   Intestinal smooth muscle cell maintenance by basic fibroblast growth factor Tissue Eng Part A, 2008; 14(8): 1395-402.
Chow, M. Duong, H. Wu, B. Tawil, B.   Mesenchymal stem cells differentiation into osteoblasts on 2D and in 3D fibrin scaffolds Wound Repair and Regeneration, 2008; 16(2): 175.
Kramerova, I. Kudryashova, E. Wu, B. Ottenheijm, C. Granzier, H. Spencer, M. J.   Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle Human Molecular Genetics, 2008; 17(21): 3271-3280.
Dave, D. S. Gunther-Lopez, V. Zhang, R. Leung, J. Kun, S. Gollapudi, K. Wu, B. Rodriguez, L. V.   Periurethral injection of autologous adipose-derived stem cells with hepatocyte growth factor-impregnated PLGA microspheres for treatment of stress urinary incontinence in an animal model Journal of Urology, 2008; 179(4): 109-109.
Heydarkhan-Hagvall, S. Schenke-Layland, K. Dhanasopon, A. P. Rofail, F. Smith, H. Wu, B. M. Shemin, R. Beygui, R. E. MacLellan, W. R.   Three-dimensional electrospun ECM-based hybrid scaffolds for cardiovascular tissue engineering Biomaterials, 2008; 29(19): 2907-2914.
Brown DA, MacLellan WR, Laks H, Dunn JC, Wu BM, Beygui RE   Analysis of oxygen transport in a diffusion-limited model of engineered heart tissue Biotechnol Bioeng, 2007; 97(4): 962-75.
Brown DA, MacLellan WR, Wu BM, Beygui RE   Analysis of pH gradients resulting from mass transport limitations in engineered heart tissue Annals of Biomed Eng, 2007; 35(11): 1885-1897.
Choi CH. Hagwall SH. Wu BM. Dunn JCY. Kim CJ   Cell interactions with 3D sharp tip nanotopography Biomaterials, 2007; 28(9): 1672-9.
Lee M. Wu BM. Dunn JYC   Effect of scaffold architecture and pore size on smooth muscle cell growth J. Biomed. Mat Res. Part A, 2007; 87(4): 1010-6.
Hagerman E. Shim J. Gupta V. Wu BM   Evaluation of laser spallation as a technique for measurement of cell adhesion strength J. Biomed. Mat. Res. Part A 82A, 2007; 82(4): 852-860.
Mack JJ, Cox BN, Lee M, Dunn JYC, Wu BM   Magnetically Actuable Polymer Nanocomposites for Bioengineering Applications J. Mater. Sci, 2007; 42(15): 6139-6147.
Cowan CM, Aghaloo T, Chou YF, Walder B, Zhang X, Soo C, Ting K, Wu BM.   MicroCT Evaluation of Three-Dimensional Mineralization in Response to BMP-2 Doses In Vitro and in Critical Sized Rat Calvarial Defects, Tissue Engineering, 2007; 13(3): 501-512.
Lee M. Iruela Arispe ML. Wu BM. Dunn JCY   Modulation of protein delivery from modular polymer scaffolds Biomaterials, 2007; 28(10): 1862-70.
Lee, M. Chen, T. T. Iruela-Arispe, M. L. Wu, B. M. Dunn, J. C. Y.   Modulation of protein delivery from modular polymer scaffolds Biomaterials, 2007; 28(10): 1862-1870.
Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu, BM, Harland R, Blau HM, Longaker MT   Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation J. Biol Chem, 2007; 282(36): 26450-26459.
Aghaloo T, Amantea CM. Cowan KM, Richardson JA, Wu B, Parhami F, Tetradis S   Oxysterols enhance osteoblast differentiation in vitro and bone healing in vivo J. Orthop Res, 2007; 25(11): 1488-1497.
Wan DC, Siedhoff MT, Kwan MD, Nacamuli RP, Wu BM, Longaker MT   Refining Retinoic Acid Stimulation for Osteogenic Differentiation of Murine Adipose-Derived Adult Stromal Cells Tissue Engineering, 2007; 13(7): 1623-1631.
Cowan, C. M. Jiang, X. Q. Hsu, T. Soo, C. Zhang, B. J. Wang, J. Z. Kuroda, S. Wu, B. Zhang, Z. Y. Zhang, X. L. Ting, K.   Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts Journal of Bone and Mineral Research, 2007; 22(6): 918-930.
Cowan CM, Jiang X, Hsu T, Soo C, Zhang J, Wang J, Kuroda S, Wu B, Zhang Z, Zhang X, Ting K   Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts J Bone Mineral Res, 2007; 22(6): 918-30.
Petrigliano FA, English C. Barba D. Esmende S. Wu BM. McAllister MD   The Effects of Local bFGF Release and Uniaxial Strain on Cellular Adaptation and Gene Expression in a 3D Environment: Implications for Ligament Tissue Engineering Tissue Engineering, 2007; 13(11): 1-11.
Lu SS, Zhang X, Soo C, Hsu T, Napoli A, Aghaloo T, Wu BM, Tsou P, Ting K, Wang JC   The osteoinductive properties of Nell-1 in rat spinal fusion model The Spine Journal, 2007; 7(1): 50-60.
Yuki I, Lee D, Murayama Y, Chiang A, Vinters HV, Nishimura I, Wang CJ, Ishii A, Wu BM, Vinuela V   Thrombus organization and healing in an experimental aneurysm model. Part II. The effect of various types of bioabsorbable polymeric coils J. Neurosurgery, 2007; 107(1): 109-120.
Lee D, Yuki I, Murayama Y, Chiang A, Nishimura I, Vinters HV, Wang CJ, Nien YL, Ishii A, Wu BM, Vinuela F   Thrombus organization and healing in the swine experimental aneurysm model. Part I. A histological and molecular analysis J. Neurosurgery, 2007; 107(1): 94-108.
Dunn JCY. Chan WY, Cristini V. Kim JS. Lowengrub J. Singha S. Wu BM   Analysis of Cell Growth in Three-Dimensional Scaffolds Tissue Engineering, 2006; 12: 705-716.
Rodriguez LV. Alfonso Z. Zhang R. Leung J. Wu BM. Ignarro LJ.   Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells PNAS, 2006; 103(32): 12167-12172.
Mendoza J., Chang C., Blalock CL., Atkinson JB., WU BM., Dunn JYC.   Contractile Function of the Mechanically Lengthened Intestine J. Surgical Research, 2006; 136(1): 8-12.
Puapong DP., Wu BM., Lam MM., Atkinson JB., Dunn JCY.   Distension enterogenesis: Increasing the Size and Function of Small Intestine J. Pediatric Surgery , 2006; 41(4): 763-7.
Catelas I. Sese N. Dunn JCY. Helgerson S. Tawil B. Wu BM   Human Mesenchymal Stem Cells Proliferation and Osteogenic Differentiation in Fibrin Gels in vitro Tissue Engineering, 2006; 12(8): 1-12.
Hagerman EM. Chao SHH. Dunn JCY. Wu BM   Initial Adhesion Events for IEC-6: signal transduction, cell spreading, and cell adhesion strength Journal of Biomedical Materials Research , 2006; 76(2): 272-278.
Aghaloo T, Cowan K, Chou YF, Zhang X, Lee HF, Miao S, Hong N, Kuroda S, Wu B, Ting K, Soo C   Nell-1 Induced Bone Regeneration in Calvarial Defects Am J Pathol, 2006; 169(3): 903-15.
Cowan, C. M. Cheng, S. Ting, K. Soo, C. Walder, B. Wu, B. Kuroda, S. Zhang, X. L.   Nell-1 induced bone formation within the distracted intermaxillary suture Bone, 2006; 38(1): 48-58.
Cowan, C. M. Cheng, S. Ting, K. Soo, C. Walder, B. Wu, B. Kuroda, S. Zhang, X.   Nell-1 induced bone formation within the distracted intermaxillary suture Bone, 2006; 38(1): 48-58.
Zhang X, Cowan K, Jiang X, Soo C, Miao S, Carpenter D, Wu, B, Kuroda K, and Ting K.   Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development Lab Invest, 2006; 86(7): 633-44.
Kramerova, I. Kudryashova, E. Wu, B. Spencer, M. J.   Regulation of the M-cadherin-beta-catenin complex by calpain 3 during terminal stages of myogenic differentiation Molecular and Cellular Biology, 2006; 26(22): 8437-8447.
Chu Y. Wu BM. McCabe ER. Dunn JCY   Serum Free cultures of murine adrenal cortical cells. J. Pediatric Surgery, 2006; 41(12): 2008-2012.
Chang P.C.Y. Mendoza J. Park J. Lam MM. Wu BM. Atkinson JB. Dunn JCY.   Sustainability of mechanically lengthened bowel in rats J. Pediactric Surgery, 2006; 41(12): 2019-2022.
Ho, W. Tawil, B. Dunn, J. C. Y. Wu, B. M.   The behavior of human mesenchymal stem cells in 3D fibrin clots: Dependence on fibrinogen concentration and clot structure Tissue Engineering, 2006; 12(6): 1587-1595.
Dunn, JCY. Wu, BM   Tissue Engineering of Intestine, Encyclopedia of Biomaterials and Biomedical Engineering, 2006; 1-7.
Petrigliano FA., McAllister MD., Wu BM.   Tissue Engineering of the ACL: A Review of Current Strategies Arthroscopy, 2006; 22(4): 441-451.
Wu, B. Kitagawa, K. Liu, B. Zhang, N. Y. Xiong, Z. M. Inagaki, C.   Attenuation of amyloid beta (Abeta)-induced inhibition of phosphatidylinositol 4-kinase activity by Abeta fragments, Abeta20-29 and Abeta31-35 Neurosci Lett, 2006; 396(2): 148-52.
Wu, B. K. Li, C. C. Chen, H. J. Chang, J. L. Jeng, K. S. Chou, C. K. Hsu, M. T. Tsai, T. F.   Blocking of G1/S transition and cell death in the regenerating liver of Hepatitis B virus X protein transgenic mice Biochem Biophys Res Commun, 2006; 340(3): 916-28.
Wu, B. Liu, J.   Commutability between the semiclassical and adiabatic limits Phys Rev Lett, 2006; 96(2): 020405.
Chang, T. H. Wu, B. R. Chiang, M. Y. Liao, S. C. Ong, C. W. Hsu, H. F. Lin, S. Y.   Synthesis and mesomorphic behavior of a donor-acceptor-type hexaazatriphenylene Org Lett, 2005; 7(19): 4075-8.
Brown, D. A. Beygui, R. E. MacLellan, W. R. Laks, H. Dunn, J. C. Wu, B. M.   Modulation of gene expression in neonatal rat cardiomyocytes by surface modification of polylactide-co-glycolide substrates J Biomed Mater Res A, 2005; 74(3): 419-29.
Wu, B. T. Hung, P. F. Chen, H. C. Huang, R. N. Chang, H. H. Kao, Y. H.   The apoptotic effect of green tea (-)-epigallocatechin gallate on 3T3-L1 preadipocytes depends on the Cdk2 pathway J Agric Food Chem, 2005; 53(14): 5695-701.
Lee, M Dunn, JC Wu, BM   Scaffold fabrication by indirect three-dimensional printing Biomaterials. , 2005; 26(20): 4281-9.
Chou, Y.F., Wulur, I., Dunn, JCY., Wu, BM.   Biomimetic Nano-Ordered Apatites , Handbook of Nanostructured Biomaterials and Their Applications. edited by H. S. Nalwa,, 2005; 2(6): 198-222.
Cowan, C. M. Aalami, O. O. Shi, Y. Y. Chou, Y. F. Mari, C. Thomas, R. Quarto, N. Nacamuli, R. P. Contag, C. H. Wu, B. Longaker, M. T.   Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover Tissue Eng, 2005; 11(3-4): 645-58.
Wu, B. Sun, Y. H. Wang, Y. W. Wang, Y. P. Zhu, Z. Y.   Characterization of transgene integration pattern in F4 hGH-transgenic common carp (Cyprinus carpio L.) Cell Res, 2005; 15(6): 447-54.
Yang CY. Brooks E. Li Y. Wong DTW. Denny P. Ho CM. Qi F. Shi W. Wolinsky L. Wu BM. Montemagno CD.   Detection of Picomolar levels of interleukin-8 in human saliva by SPR Lab on a Chip, 2005; 5(10): 1017-1023.
Wu, B. Gao, J. Wang, M. W.   Development of a complex scintillation proximity assay for high-throughput screening of PPARgamma modulators Acta Pharmacol Sin, 2005; 26(3): 339-44.
Cowan, CM Soo, C Ting, K Wu, B   Evolving concepts in bone tissue engineering Current topics in developmental biology, 2005; 66(86): 239-85.
Brown DA. Chou YF. Lam M. Beygui RE. Dunn JYC. Wu BM   Gelatin embedding cell-polymer constructs for frozen sections, J. Biomedical Materials Research, 2005; 72B: 79-85.
Chou YF. Dunn JCY. Wu BM   In vitro response of MC3T3-E1 preosteoblasts within three-dimensional apatite-coated PLGA scaffolds Journal of Biomedical Materials Research , 2005; 75(1): 81-90.
Wu, B. N. Tu, H. F. Welsh, D. G. Chen, I. J.   KMUP-1 activates BKCa channels in basilar artery myocytes via cyclic nucleotide-dependent protein kinases Br J Pharmacol, 2005; 146(6): 862-71.
Brown DA. Beygui RE. Antrobus S. Ross RS. MacLellan WR. Laks H. Dunn JYC. Wu BM.   Modulation of hypertrophy in neonatal rat cardiomyocytes by surface modification of synthetic substrates, J. Biomedical Materials Research, 2005; 74A(3): 419-429.
Wu, B. Wong, D. Lu, S. Dickstein, S. Silva, M. Gelety, T. J.   Optimal use of fresh and frozen-thawed testicular sperm for intracytoplasmic sperm injection in azoospermic patients J Assist Reprod Genet, 2005; 22(11-12): 389-94.
Jarrahy R., Huang W., Rudkin GH., Lee JM., Ishida K., Berry MD., Sukkarieh M., Wu BM., Yamaguchi DT., Miller TA.   Osteogenic differentiation is inhibited and angiogenic expression is enhanced in MC3T3-E1 cells cultured on three-dimensional scaffolds Am J Physiology – Cell Physiology, 2005; 289: 408-414.
Wu, B. Elmariah, S. Kaplan, F. S. Cheng, G. Mohler, E. R., 3rd   Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease Arterioscler Thromb Vasc Biol, 2005; 25(3): 592-7.
Wu, B. Klatzky, R. L. Shelton, D. Stetten, G. D.   Psychophysical evaluation of in-situ ultrasound visualization IEEE Trans Vis Comput Graph, 2005; 11(6): 684-93.
Lee M. Dunn JCY. Wu BM.   Scaffold Fabrication by Indirect 3D Printing, Biomaterials, 2005; 26(20): 4281-4289.
Puk CK., Gamradt S., Wu B.M., McAllister D   The Effects of Short-Term Stimulation on Fibroblast Spreading in an Invitro 3D Syste J. Biomedical Materials Research , 2005; 76(4): 665-673.
Li Y, Denny P, Ho CM, Montemagno C, Shi W, Qi F, Wu B, Wolinsky L, Wong DT.   The Oral Fluid MEMS/ NEMS Chip (OFMNC): diagnostic and translational applications Advanced Dental Resesarch, 2005; 18(1): 3-5.
Chou, Y. F. Huang, W. Dunn, J. C. Miller, T. A. Wu, B. M.   The effect of biomimetic apatite structure on osteoblast viability, proliferation, and gene expression Biomaterials, 2005; 26(3): 285-95.
Wu, B. Muller, J. D.   Time-integrated fluorescence cumulant analysis in fluorescence fluctuation spectroscopy Biophys J, 2005; 89(4): 2721-35.
Wu, B. Zhang, G. Zhang, Y. Shuang, S. Choi, M. M.   Measurement of glucose concentrations in human plasma using a glucose biosensor Anal Biochem, 2005; 340(1): 181-3.
Brown, D. A. Chou, Y. F. Beygui, R. E. Dunn, J. C. Wu, B. M.   Gelatin-embedded cell-polymer constructs for histological cryosectioning J Biomed Mater Res B Appl Biomater, 2005; 72(1): 79-85.
Wu, B. Liu, Q. Sulikowski, G. A.   Total synthesis of apoptolidinone Angew Chem Int Ed Engl, 2004; 43(48): 6673-5.
Deng, Y. M. Wu, B. J. Witting, P. K. Stocker, R.   Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1 Circulation, 2004; 110(13): 1855-60.
Wu, B. T. Su, Y. H. Tsai, M. T. Wasserman, S. M. Topper, J. N. Yang, R. B.   A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones J Biol Chem, 2004; 279(36): 37485-90.
St. John M. Li Y. Zhou XF. DennyD. Ho CM. Montemagno C. Shi WY. Qi FX. Wu BM. Sinha U. Jordan R. Wolinsky L. Park NH. Abemayor E. Wong DTW   IL-6 and IL-8: Potential Biomarkers for Oral Cavity and Oropharyngeal SSC, Arch of Otolaryngology/Head & Neck Surgery , 2004; 130(8): 929-35.
Cowan, CM., Shi S., Alami, OO., Chou, YF., Thomas R. Marie C., Quarto N., Wu BM. Longaker MT.   Adipose-derived Mesenchymal Stromal Cells Tissue Engineer Bone in Critical Sized Mouse Calvarial Defects Nature Biotechnology, 2004; 22(5): 560-567.
Dunn, J. C. Chu, Y. Lam, M. M. Wu, B. M. Atkinson, J. B. McCabe, E. R.   Adrenal cortical cell transplantation J Pediatr Surg, 2004; 39(12): 1856-8.
Park J. Puapong DP. Wu BM. Atkinson JB. Dunn JCY   Enterogenesis by Mechanical Lengthening: Morphology and Function of the Lengthened Small Intestine J. Pediatric Surg, 2004; 39(12): 1823-1827.
Wu, B. N. Lin, R. J. Lo, Y. C. Shen, K. P. Wang, C. C. Lin, Y. T. Chen, I. J.   KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels Br J Pharmacol, 2004; 142(7): 1105-14.
Kreth, J., Hagerman, E., Tam, K., Merritt, J., Wu, B.M., Myung, M., Shi, W., and Qi, F   Quantitative Analyses of Streptococcus mutans Biofilms with Quartz Crystal Microbalance, Microjet Impingement, and Confocal Microscopy Biofilms, 2004; 1(4): 277-284.
Chen, X. Grzegorczyk, T. M. Wu, B. I. Pacheco, J., Jr. Kong, J. A.   Robust method to retrieve the constitutive effective parameters of metamaterials Phys Rev E Stat Nonlin Soft Matter Phys, 2004; 70(1 Pt 2): 016608.
Yang, W. Wu, B. Asakura, S. Kohno, I. Matsuda, M.   Soluble fibrin augments spreading of fibroblasts by providing RGD sequences of fibrinogen in soluble fibrin Thromb Res, 2004; 114(4): 293-300.
Wu, B. M. Nakamura, M. Rezaee, M.   Stent implantation for coronary aneurysm with edge stenosis: angiographic and intravascular analysis J Invasive Cardiol, 2004; 16(3): 149-51.
Wu, B.   Testing three competing hypotheses for explaining lethal violence Violence Vict, 2004; 19(4): 399-411.
Chou YF. Chiou WA. Xu Y. Dunn JCY. Wu BM   The Effect of pH on Structural Evolution of Accelerated Biomimetic Apatite Formation Biomaterials, 2004; 25(22): 5323-5331.
Wu, B. Li, P. Liu, Y. Lou, Z. Ding, Y. Shu, C. Ye, S. Bartlam, M. Shen, B. Rao, Z.   3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex Proc Natl Acad Sci U S A, 2004; 101(22): 8348-53.
Liu, B. Hattori, N. Jiang, B. Nakayama, Y. Zhang, N. Y. Wu, B. Kitagawa, K. Taketo, M. Matsuda, H. Inagaki, C.   Single cell RT-PCR demonstrates differential expression of GABAC receptor rho subunits in rat hippocampal pyramidal and granule cells Brain Res Mol Brain Res, 2004; 123(1-2): 1-6.
He, Y. Yang, J. Wu, B. Robinson, D. Sprankle, K. Kung, P. P. Lowery, K. Mohan, V. Hofstadler, S. Swayze, E. E. Griffey, R.   Synthesis and evaluation of novel bacterial rRNA-binding benzimidazoles by mass spectrometry Bioorg Med Chem Lett, 2004; 14(3): 695-9.
De Ugarte DA. Choi E. Weitzbuch H. Wulur I. Caulkins C. Wu BM. Fonkalsrud EW. Atkinson JB. Dunn JCY   Mucosal regeneration of a duodenal defect using small intestine submucosa The American Surgeon, 2004; 70(1): 49-51.
Wu, B. Yang, J. Robinson, D. Hofstadler, S. Griffey, R. Swayze, E. E. He, Y.   Synthesis of linked carbohydrates and evaluation of their binding for 16S RNA by mass spectrometry Bioorg Med Chem Lett, 2003; 13(22): 3915-8.
Wu, B. Abbott, T. Fishman, D. McMurray, W. Mor, G. Stone, K. Ward, D. Williams, K. Zhao, H.   Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data Bioinformatics, 2003; 19(13): 1636-43.
Qin, W. Tyshenko, M. G. Wu, B. S. Walker, V. K. Robertson, R. M.   Cloning and characterization of a member of the Hsp70 gene family from Locusta migratoria, a highly thermotolerant insect Cell Stress Chaperones, 2003; 8(2): 144-52.
Sukotjo C. Lin A. Song KK. Ogawa I. Wu BM. Nishimura I   Oral fibroblast expression of wound inducible transcript-3.0 (wit-3.0) accelerates collagen gel contraction in vitro J. Biological Chemistry, 2003; 278(51): 51527-51534.
Zhang X. Carpenter D. Bokui N. Soo C. MiaoS. Truong T. Wu BM. Chen I. Vastardis H. Tanizawa K. Kuroda S. Ting K.   Overexpression of Nell-1, a craniosynostosis associated gene, induces apoptosis in osteoblasts during craniofacial development Journal of Bone and Mineral Research , 2003; 18(12): 2126-2134.
Nishimura I. Garrell R. Hedrick M. Iida K. Osher S. Wu BM   Precursor tissue analogs as a tissue-engineering strategy Tissue Engineering, 2003; 9(1): 77-89.
Hong, B. Wu, B. Li, Y.   Production of C-terminal amidated recombinant salmon calcitonin in Streptomyces lividans Appl Biochem Biotechnol, 2003; 110(2): 113-23.
Wu, B. Yee, A. Pineda-Lucena, A. Semesi, A. Ramelot, T. A. Cort, J. R. Jung, J. W. Edwards, A. Lee, W. Kennedy, M. Arrowsmith, C. H.   Solution structure of ribosomal protein S28E from Methanobacterium thermoautotrophicum Protein Sci, 2003; 12(12): 2831-7.
Drachman, D. B. Wu, J. M. Miagkov, A. Williams, M. A. Adams, R. N. Wu, B.   Specific immunotherapy of experimental myasthenia by genetically engineered APCs: the “guided missile” strategy Ann N Y Acad Sci, 2003; 998: 520-32.
Chen, J. Guo, J. Sun, J. Jiang, W. Wu, B.   TCM treatment of Parkinson’s syndrome–a report of 40 cases J Tradit Chin Med, 2003; 23(3): 168-9.
Roger P. Woods, M.D.

Roger Woods, M.D.

Faculty Member

Professor
Department of Neurology
Department of Psychiatry & Biobehavioral Sciences
David Geffen School of Medicine
University of California, Los Angeles

 

Ahmanson-Lovelace Brain Mapping Center
BOX 957085
660 Charles E Young Drive South
Los Angeles, CA 90095

Ernest M. Wright, D.Sc.

Ernest Wright, Ph.D., D.Sc.

Faculty Member

Distinguished Professor, Emeritus on Recall
Department of Medicine
Department of Physiology
David Geffen School of Medicine
University of California, Los Angeles

 

Center for Health Sciences 53-317
10833 Le Conte Ave.
Los Angeles, CA 90095

 

Biography

Wright was born and educated in Ireland. He earned his B.Sc. in Physiology and Chemistry from the University of London and his Ph.D. in Physiology at the University of Sheffield under the tutelage of Professor David Smyth FRS. He was a member of the faculty at Sheffield for two years prior to a Fellowship at Harvard where he studied with Jared Diamond, Peter Curran and Stanley Schultz in the Biophysics Laboratory headed by Arthur K. Solomon. In 1978 he was awarded a D.Sc. in Physiology from the University of London. In 1967 he joined the faculty of the Department of Physiology at UCLA School of Medicine headed by Wilfred Mommaerts. Wright served as Chair of Physiology between 1987 and 2000 and was awarded the Sherman M. Mellinkoff Distinguished Professorship in Medicine 1999. He was Visiting Professor at the Center for Advanced Studies at the National Polytechnic Institute in Mexico City in 1973, at the Max Planck Institute for Biophysics in Frankfurt in 1974-1975, and Queen Elizabeth College, London in 1977. He has served as Chair and member of the Physiology Study Section at the NIH, a member of the Eli Broiad Medical Foundation, and an advisor to the Swiss National Science Foundation, Boehringer Inglheim, Xenoport, and UCSF Center for the Structure of Membrane proteins.

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