Parnian Hemmati

As a Ph.D. candidate in Mechanical Engineering, my research focuses on the vital role of cerebrospinal fluid (CSF) and glymphatic flow in maintaining brain health and function. CSF acts as a protective cushion for the brain, absorbing shocks and reducing the risk of injury, while also playing a crucial role in waste removal by transporting metabolic byproducts and toxins away from the brain. The glymphatic system enhances this waste removal by facilitating the clearance of harmful proteins, such as beta-amyloid, which are linked to neurodegenerative diseases like Alzheimer’s. My research focuses on exploring the mechanisms of fluid, particle, and ion transport within the glymphatic system, as well as investigating the effect of external factors, such as head impact, on the CSF flow. By integrating cutting-edge engineering approaches with bioscience and clinical research, I aim to advance our understanding of brain health and develop innovative solutions. Additionally, I incorporate data science techniques to combine numerical modeling and experimental data, enhancing the accuracy and applicability of the findings for translational research in neurological disorders.

Mentor: Mayumi Prins, Ph.D.