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Beate Ritz

Beate Ritz, M.D., Ph.D.

Biography

Beate Ritz joined the faculty of the School of Public Health at UCLA in 1995 and is currently Professor and Vice Chair of the Epidemiology Department and holds co-appointments in the Environmental Health department at the UCLA School of Public Health and in Neurology, UCLA School of Medicine; she is a member of the Center for Occupational and Environmental Health (COEH), the Southern California Environmental Health Science Center (SCEHSC), and co-directs the NIEHS-funded UCLA Center for Gene-Environment Studies of Parkinson’s disease.

Dr. Ritz received her MD and a PhD in Medical Sociology from the University of Hamburg Germany in 1983 and 1987; she was a research fellow and resident at the Psychiatric University-Hospital in Hamburg from 1987-1989, and received doctoral training and a PhD degree in Epidemiology in 1995 from UCLA.

Her research focuses on the health effects of occupational and environmental toxins such as pesticides, ionizing radiation, and air pollution on chronic diseases including neurodegenerative disorders (Parkinson’s disease), cancers, and adverse birth outcomes and asthma. She previously investigated the causes of cancer in chemical toxin and radiation exposed workers and assessed the impact of ergonomic work-place factors on musculo-skeletal disorders. For the past decade, she studied the effects of air pollution on adverse birth outcomes as well as asthma in children in Southern California. In 2006, she received the Robert M Zweig Memorial award for outstanding achievement in air quality and medicine from the South Coast Air Quality Management District. She also spend the past 15 years investigating the long-term effects of pesticide exposures on Parkinson’s disease and cancers and is currently conducting a project to implement a Parkinson’s disease registry required by a new law in California.

In her research she uses geographic information system (GIS) modeling of environmental exposures including pesticide use and traffic related air pollution in California and investigates links between genetic susceptibility factors and environmental exposures in populations. She is directing and collaborating in a large number of federally (NIH, DOD), state (California Air Resources Board), and foundation (Michael J Fox Foundation) funded research projects.

Publications

A selected list of publications:

Manthripragada A, Cockburn M, Costello S, Bronstein J, Ritz B.   Paraoxonase-1 gene Leu-Met 55 polymorphism may modify the estimated effects of agricultural organophosphate exposure on Parkinson’s disease. In Press: Epidemiology, , 2009; .
Ritz–Publications PD Gatto N   Cockburn M, Bronstein J, Ritz B. Well Water Consumption and Parkinson’s Disease in Rural California. , In Press EHP , 2009; .
Costello Sadie, Cockburn Myles, Bronstein Jeff, Zhang Xinbo, Ritz Beate   Parkinson’s disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California American journal of epidemiology, 2009; 169(8): 919-26.
Rhodes Shannon L, Ritz Beate   Genetics of iron regulation and the possible role of iron in Parkinson’s disease Neurobiology of disease, 2008; 32(2): 183-95.
Ritz B, Rull R   Assessment of Environmental Exposures from Agricultural Pesticides in Childhood Leukemia Studies: Challenges and Opportunities, In Press: Radiation Protection Dosimetry, 2008; .
Rhodes SL, Ritz B   Genetics of Iron Regulation and the Possible Role of Iron in Parkinson’s Disease, In Press: Neurobiology of Disease, 2008; .
Rugbjerg K, Ritz B, Korbo L, Martinussen N, Olsen JH   Risk for Parkinson’s Disease After Hospitalization for a Head Injury: A Population-Based Case-Control Study, In Press: BMJ, 2008; .
Wahner AD, Bronstein JF, Bordelon YM, Ritz B   Statin Use and the Risk of Parkinson’s Disease, Neurology, 2008; 70(16 pt. 2): 1418-22.
Wahner Angelika D, Bronstein Jeff M, Bordelon Yvette M, Ritz Beate   Statin use and the risk of Parkinson disease Neurology, 2008; 70(16 Pt 2): 1418-22.
Goldberg Daniel W, Wilson John P, Knoblock Craig A, Ritz Beate, Cockburn Myles G   An effective and efficient approach for manually improving geocoded data International journal of health geographics, 2008; 7(2): 60.
Rugbjerg Kathrine, Ritz Beate, Korbo Lise, Martinussen Nick, Olsen Jørgen H   Risk of Parkinson’s disease after hospital contact for head injury: population based case-control study BMJ (Clinical research ed.), 2008; 337(2): a2494.
Krishnadasan A, Kennedy N, Zhao Y, Morgenstern H, Ritz B   Nested Case-Control Study of Occupational Physical Activity and Prostate Cancer Among Workers Using a Job Exposure Matrix, Cancer Causes Control, 2008; 1: 107-14.
Ritz B, Wilhelm M, Hoggatt KJ, Ghosh JKC   Ambient Air Pollution and Preterm Birth in the UCLA Environment and Pregnancy Outcomes Study, American journal of industrial medicine, 2007; 166(9): 1045-52.
Wahner Angelika D, Bronstein Jeff M, Bordelon Yvette M, Ritz Beate   Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease Neurology, 2007; 69(19): 1836-42.
Ritz Beate, Ascherio Alberto, Checkoway Harvey, Marder Karen S, Nelson Lorene M, Rocca Walter A, Ross G Webster, Strickland Daniel, Van Den Eeden Stephen K, Gorell Jay   Pooled analysis of tobacco use and risk of Parkinson disease Archives of neurology, 2007; 64(7): 990-7.
Rempel DM, Wang PC, Janowitz I, Harrison RJ, Yu F, Ritz B   A Randomized Controlled Trial Evaluating the Effects of New Task Chairs on Shoulder and Neck Pain Among Sewing Machine Operators: The Los Angeles Garment Study, Spine, 2007; 32(9): 931-38.
Karr C, Lumley T, Shepherd K, Davis R, Larson T, Ritz B, Kaufman J   Effect of Subchronic and Chronic Exposure to Ambient Air Pollutants on Infant Bronchiolitis, Am J Epidemiol, 2007; 165(5): 553-60.
Lewis C, Suffet HI, Hoggatt KJ, Ritz B   Estimated Effects of Disinfection By-Products on Preterm Birth in a Population Served by a Single Water Utility, Environmental Health Perspectives, 2007; 115(2): 290-5.
Wahner AD, Glatt CE, Bronstein JF, Ritz B.   Glutathione S-Transferase Mu, Omega, Pi, And Theta Class Variants And Smoking In Parkinson’s Disease. Neurosci Lett. 2007 Feb 21;413(3):274-8, , 2007; .
Wahner AD, Glatt CE, Bronstein JF, Ritz B   Glutathione S-Transferase Mu, Omega, Pi, and Theta Class Variants and Smoking in Parkinson’s Disease, Neurosci Lett. Perspect, 2007; 413(3): 274-8.
Wahner AD, Sinsheimer JS, Bronstein JF, Ritz B   Inflammatory Cytokine Gene Polymorphisms Increase Risk of Parkinson’s Disease, Arch Neurol, 2007; 64(6): 836-40.
Krishnadasan A, Kennedy N, Zhao Y, Morgenstern H, Ritz B   Nested Case- Control Study of Occupational Chemical Exposures and Prostate Cancer in Aerospace and Radiation Worker, American Journal of Industrial Medicine, 2007; 50(5): 383-90.
Wahner AD, Bronstein JF, Bordelon YM, Ritz B   Nonsteroidal Anti-Inflammatory Drugs May Protect Against Parkinson’s Disease, Neurology, 2007; 69(19): 1836-42.
Ritz B, Ascherio A, Checkoway H, Marder KS, Nelson LM, Rocca WA, Ross GW, Strickland D, Van Den Eeden SK, Gorell J   Pooled Analysis of Tobacco Use and Risk of Parkinson’s Disease, Archives of Neurology, 2007; 64(7): 990-7.
Mengy YY, Wilhelm M, Rull R, English P, Ritz B   Traffic and Outdoor Air Pollution Levels Near REsidences and Poorly-Controlled Asthma in Adults, Ann Asthma, Allergy, Immunol, 2007; 98(5): 455-63.
Wahner Angelika D, Sinsheimer Janet S, Bronstein Jeff M, Ritz Beate   Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease Archives of neurology, 2007; 64(6): 836-40.
Wang PC, Rempel D, Harrison R, Chan J, Ritz B   Work-Organizational and Personal Factors Associated with Upper Body Musculoskeletal Disorders Among Sewing Machine Operators Occupational Environmental Medicine, 2007; .
Elbaz Alexis, Nelson Lorene M, Payami Haydeh, Ioannidis John P A, Fiske Brian K, Annesi Grazia, Carmine Belin Andrea, Factor Stewart A, Ferrarese Carlo, Hadjigeorgiou Georgios M, Higgins Donald S, Kawakami Hideshi, Krüger Rejko, Marder Karen S, Mayeux Richard P, Mellick George D, Nutt John G, Ritz Beate, Samii Ali, Tanner Caroline M, Van Broeckhoven Christine, Van Den Eeden Stephen K, Wirdefeldt Karin, Zabetian Cyrus P, Dehem Marie, Montimurro Jennifer S, Southwick Audrey, Myers Richard M, Trikalinos Thomas A   Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson’s disease: a large-scale international study Lancet neurology, 2006; 5(11): 917-23.
Ritz Beate, Costello Sadie   Geographic model and biomarker-derived measures of pesticide exposure and Parkinson’s disease Annals of the New York Academy of Sciences, 2006; 1076(11): 378-87.
Ritz B, Zhao Y, Krishnadasan A, Kennedy N, Morgenstern H   Estimated Effects of Hydrazine Exposure on Cancer Incidence and Mortality in Aerospace Workers, Epidemiology, 2006; 17(2): 154-61.
Ritz B, Costello S   Geographic Model and Biomarker-Derived Measures of Pesticide Exposure and Parkinson’s Disease, Ann NY Academy Sci, 2006; 1076: 378-87.
Elbaz A, Nelson LM, Ritz B, et al   Lack of Replication of Thirteen Single-Nucleotide Polymorphisms Implicated in Parkinson’s Disease: A Large-Scale International Study, Lancet Neurol, 2006; 5(11): 917-23.
Schernhammer Eva, Chen Honglei, Ritz Beate   Circulating melatonin levels: possible link between Parkinson’s disease and cancer risk? Cancer causes & control : CCC, 2006; 17(4): 577-82.
Glatt Charles E, Wahner Angelika D, White Daniel J, Ruiz-Linares Andres, Ritz Beate   Gain-of-function haplotypes in the vesicular monoamine transporter promoter are protective for Parkinson disease in women Human molecular genetics, 2006; 15(2): 299-305.
Kang Gail A, Bronstein Jeff M, Masterman Donna L, Redelings Matthew, Crum Jarrod A, Ritz Beate   Clinical characteristics in early Parkinson’s disease in a central California population-based study Movement disorders : official journal of the Movement Disorder Society, 2005; 20(9): 1133-42.
Ritz B, Tager I, Balmes J   Can Lessons from Public Health Disease Surveillance be Applied to Environmental Public Health Tracking?, Environmental Health Perspectives, 2005; 113(3): 243-9.
Rull Ru, Ritz B   Historical Pesticide Exposure in California Using Pesticide Use Reports and Land-Use Surveys: An Assessment of Misclassification Error and Bias, Environmental Health Perspectives, 2003; 111(13): 1582-9.
Wilhelm M, Ritz B   Residential Proximity to Traffic and Adverse Birth Outcomes in Los Angeles County, California, 1994-1996, Environmental Health Perspectives, 2003; 111(2): 207-16.
Ritz B, Yu F, Chapa G, Fruin S, Shaw G, Harris J   Ambient Air Pollution and Birth Defects, Am J Epidemiol, 2002; 155: 17-25.
Jacob B, Ritz B, Gehring U, Koch A, Bischof W, Wichmann HE, Heinrich J for the INGA-Study group   Indoor Exposure to Molds and Allergic Sensitization, Environmental Health Perspectives, 2002; 110(7): 647-53.
Morgenstern H, Ritz B   Effects of Low-Level Ionizing Radiation and Chemical Exposures on Cancer Mortality in Nuclear and Aerospace Workers: Findings from the UCLA Rocketdyne Study, Occupational Medicine, 2001; 16(2): 219-37.
Ritz B, Yu F, Chapa G, Fruin S   Effect of Air Pollution on Preterm Birth Among Children Born in Southern California Between 1989 and 1993, Epidemiology, 2000; 11: 502-11.
Ritz B, Yu F   Parkinson’s Disease Mortality And Pesticide Exposure in California 1984-1994, International Journal of Epidemiology, 2000; 29: 323-9.
Ritz B, Yu F.   Parkinson’s Disease Mortality And Pesticide Exposure In California 1984 1994. International Journal of Epidemiology, 2000, Vol. 29:323-329, , 2000; .
Ritz B, Morgenstern H, Crawford-Brown D, Young B   The Effects of Internal Radiation Exposure on Cancer Mortality in Nuclear Workers at Rocketdyne/Atomics International, Environmental Health Perspectives, 2000; 108: 743-51.
Felix E. Schweizer, Ph.D.

Felix Schweizer, Ph.D.

Biography

Felix E. Schweizer was born in Basel, Switzerland and conducted his graduate research in the laboratory of Prof. Max M. Burger under the direction of Dr. Theo Schafer. He received his PhD degree in biochemistry summa cum laude from the University of Basel in 1989. From 1990 to 1994, he was a post-doctoral fellow in the Department of Molecular and Cellular Physiology at Stanford University in the laboratory of Prof. Richard W. Tsien. From 1994 to 1998, he was postdoctoral fellow in the Department of Neurobiology at Duke University in the laboratory of Professor George J. Augustine. Dr. Schweizer joined the Department of Neurobiology in the David Geffen School of Medicine at UCLA in 1998 as Assistant Professor and was promoted to Full Professor in 2010. Dr. Schweizer’s research interests concern the molecular mechanisms by which neurons communicate, the regulation of communication by neurons and how alterations in neuronal communication might contribute to neuronal diseases. The Schweizer laboratory uses electrophysiological and optical tools to investigate the dynamic molecular mechanisms underlying the regulation of neurotransmitter release. We are particularly interested in the role of protein ubiquitination in regulating neuronal excitability and synaptic transmission. In collaboration with Dr. James Wohlschlegel, we used multiplexed SILAC and identified synaptic proteins that are dynamically regulated. More recently, in collaboration with Dr. David Krantz, we are using pesticides linked to neuro-degenerative disorders as unbiased tools identify novel pathways that might be involved in early signs of degeneration. In addition, we are characterizing transmission at the first synapse of the vestibular system, i.e. between utricular sensory hair cells and primary afferent neurons. In collaboration with Dr. Larry Hoffman we are finding that changing the gravitational load alters synaptic structures. We are now using serial EM and EM tomography in addition to physiology and cell biology to define in more detail the transfer function between head-movement input and afferent nerve-firing output.

Elyse J. Singer, M.D.

Elyse Singer, M.D.

Biography

 

Dr. Singer is affiliated with the following Institutions:

Publications

A selected list of publications:

Rose Rebecca R, Nolan David J, Maidji Ekaterina, Stoddart Cheryl, Singer Elyse J, Lamers Susanna, McGrath Michael   Eradication of HIV from Tissue Reservoirs: Challenges for the Cure AIDS research and human retroviruses, 2017; .
Kuhn Taylor, Sayegh Philip, Jones Jacob D, Smith Jason, Sarma Manoj K, Ragin A, Singer Elyse J, Albert Thomas M, Thames April D, Castellon Steven A, Hinkin Charles H   Improvements in brain and behavior following eradication of hepatitis C Journal of neurovirology, 2017; .
Christensen Bianca, Qin Zijian, Byrd Desiree A, Yu Fang, Morgello Susan, Gelman Benjamin B, Moore David J, Grant Igor, Singer Elyse J, Fox Howard S, Baccaglini Lorena   Measures of Physical and Mental Independence Among HIV-Positive Individuals: Impact of Substance Use Disorder AIDS research and human retroviruses, 2017; .
Solomon Isaac H, De Girolami Umberto, Chettimada Sukrutha, Misra Vikas, Singer Elyse J, Gabuzda Dana   Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era BMC infectious diseases, 2017; 17(1): 151.
Thames April D, Kuhn Taylor P, Mahmood Zanjbeel, Bilder Robert M, Williamson Timothy J, Singer Elyse J, Arentoft Alyssa   Effects of social adversity and HIV on subcortical shape and neurocognitive function Brain imaging and behavior, 2017; 17(1): 151.
Lamers Susanna L, Rose Rebecca, Maidji Ekaterina, Agsalda-Garcia Melissa, Nolan David J, Fogel Gary B, Salemi Marco, Garcia Debra L, Bracci Paige, Yong William, Commins Deborah, Said Jonathan, Khanlou Negar, Hinkin Charles H, Sueiras Miguel Valdes, Mathisen Glenn, Donovan Suzanne, Shiramizu Bruce, Stoddart Cheryl A, McGrath Michael S, Singer Elyse J   HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads Journal of virology, 2016; 90(20): 8968-83.
Rose Rebecca, Lamers Susanna L, Nolan David J, Maidji Ekaterina, Faria N R, Pybus Oliver G, Dollar James J, Maruniak Samuel A, McAvoy Andrew C, Salemi Marco, Stoddart Cheryl A, Singer Elyse J, McGrath Michael S   HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer Journal of virology, 2016; 90(20): 8984-93.
Bowen Lauren N, Tyagi Richa, Li Wenxue, Alfahad Tariq, Smith Bryan, Wright Mary, Singer Elyse J, Nath Avindra   HIV-associated motor neuron disease: HERV-K activation and response to antiretroviral therapy Neurology, 2016; 87(17): 1756-1762.
Levine Andrew J, Soontornniyomkij Virawudh, Achim Cristian L, Masliah Eliezer, Gelman Benjamin B, Sinsheimer Janet S, Singer Elyse J, Moore David J   Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV Journal of neurovirology, 2016; 22(4): 431-41.
Levine Andrew J, Quach Austin, Moore David J, Achim Cristian L, Soontornniyomkij Virawudh, Masliah Eliezer, Singer Elyse J, Gelman Benjamin, Nemanim Natasha, Horvath Steve   Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders Journal of neurovirology, 2016; 22(3): 366-75.
Levine Andrew J, Palomo Manuel, Hinkin Charles H, Valdes-Sueiras Miguel, Lopez Enrique, Mathisen Glenn, Donovan Suzanne, Singer Elyse J   A comparison of screening batteries in the detection of neurocognitive impairment in HIV-infected Spanish speakers Neurobehavioral HIV medicine, 2016; 3(1): 79-86.
Panos Stella E, Hinkin Charles H, Singer Elyse J, Thames April D, Patel Sapna M, Sinsheimer Janet S, Del Re A C, Gelman Benjamin B, Morgello Susan, Moore David J, Levine Andrew J   Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity Neurobehavioral HIV medicine, 2016; 5(1): 11-22.
Singer Elyse J, Thames April D   Neurobehavioral Manifestations of Human Immunodeficiency Virus/AIDS: Diagnosis and Treatment Neurologic clinics, 2016; 34(1): 33-53.
Thames April D, Briones Marisa S, Magpantay Larry I, Martinez-Maza Otoniel, Singer Elyse J, Hinkin Charles H, Morgello Susan, Gelman Benjamin B, Moore David J, Heizerling Keith, Levine Andrew J   The role of chemokine C-C motif ligand 2 genotype and cerebrospinal fluid chemokine C-C motif ligand 2 in neurocognition among HIV-infected patients AIDS (London, England), 2015; 29(12): 1483-91.
Anderson Albert M, Harezlak Jaroslaw, Bharti Ajay, Mi Deming, Taylor Michael J, Daar Eric S, Schifitto Giovanni, Zhong Jianhui, Alger Jeffry R, Brown Mark S, Singer Elyse J, Campbell Thomas B, McMahon Deborah D, Buchthal Steven, Cohen Ronald, Yiannoutsos Constantin, Letendre Scott L, Navia Bradford A, Navia Bradford A   Plasma and Cerebrospinal Fluid Biomarkers Predict Cerebral Injury in HIV-Infected Individuals on Stable Combination Antiretroviral Therapy Journal of acquired immune deficiency syndromes (1999), 2015; 69(1): 29-35.
Kim Joseph Y, Singer Elyse J, Bonelli Laura, Klausner Jeffrey D   A case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease Journal of the International Association of Providers of AIDS Care, 2015; 13(3): 196-9.
Fogel Gary B, Lamers Susanna L, Levine Andrew J, Valdes-Sueiras Miguel, McGrath Michael S, Shapshak Paul, Singer Elyse J   Factors related to HIV-associated neurocognitive impairment differ with age Journal of neurovirology, 2015; 21(1): 56-65.
Thames April D, Castellon Steven A, Singer Elyse J, Nagarajan Rajakumar, Sarma Manoj K, Smith Jason, Thaler Nicholas S, Truong Jonathan Hien, Schonfeld Daniel, Thomas M Albert, Hinkin Charles H   Neuroimaging abnormalities, neurocognitive function, and fatigue in patients with hepatitis C Neurology® neuroimmunology & neuroinflammation, 2015; 2(1): e59.
Lou Jerry J, Mirsadraei Leili, Sanchez Desiree E, Wilson Ryan W, Shabihkhani Maryam, Lucey Gregory M, Wei Bowen, Singer Elyse J, Mareninov Sergey, Yong William H   A review of room temperature storage of biospecimen tissue and nucleic acids for anatomic pathology laboratories and biorepositories Clinical biochemistry, 2014; 47(4-5): 267-73.
Shabihkhani Maryam, Lucey Gregory M, Wei Bowen, Mareninov Sergey, Lou Jerry J, Vinters Harry V, Singer Elyse J, Cloughesy Timothy F, Yong William H   The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings Clinical biochemistry, 2014; 47(4-5): 258-66.
Panos Stella E, Del Re A C, Thames April D, Arentsen Timothy J, Patel Sapna M, Castellon Steven A, Singer Elyse J, Hinkin Charles H   The impact of neurobehavioral features on medication adherence in HIV: evidence from longitudinal models AIDS care, 2014; 26(1): 79-86.
Levine Andrew J, Horvath Steve, Miller Eric N, Singer Elyse J, Shapshak Paul, Baldwin Gayle C, Martínez-Maza Otoniel, Witt Mallory D, Langfelder Peter   Transcriptome analysis of HIV-infected peripheral blood monocytes: gene transcripts and networks associated with neurocognitive functioning Journal of neuroimmunology, 2013; 265(1-2): 96-105.
Gongvatana Assawin, Harezlak Jaroslaw, Buchthal Steven, Daar Eric, Schifitto Giovanni, Campbell Thomas, Taylor Michael, Singer Elyse, Algers Jeffrey, Zhong Jianhui, Brown Mark, McMahon Deborah, So Yuen T, Mi Deming, Heaton Robert, Robertson Kevin, Yiannoutsos Constantin, Cohen Ronald A, Navia Bradford, Navia Bradford   Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy Journal of neurovirology, 2013; 19(3): 209-18.
Hua Xue, Boyle Christina P, Harezlak Jaroslaw, Tate David F, Yiannoutsos Constantin T, Cohen Ron, Schifitto Giovanni, Gongvatana Assawin, Zhong Jianhui, Zhu Tong, Taylor Michael J, Campbell Thomas B, Daar Eric S, Alger Jeffry R, Singer Elyse, Buchthal Steve, Toga Arthur W, Navia Bradford, Thompson Paul M, Thompson Paul M   Disrupted cerebral metabolite levels and lower nadir CD4Â + counts are linked to brain volume deficits in 210 HIV-infected patients on stable treatment NeuroImage. Clinical, 2013; 3(2): 132-42.
Singer Elyse J, Valdes-Sueiras Miguel, Commins Deborah L, Yong William, Carlson Margrit   HIV stroke risk: evidence and implications Therapeutic advances in chronic disease, 2013; 4(2): 61-70.
Levine Andrew J, Miller Jeremy A, Shapshak Paul, Gelman Benjamin, Singer Elyse J, Hinkin Charles H, Commins Deborah, Morgello Susan, Grant Igor, Horvath Steve   Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease BMC medical genomics, 2013; 6(2): 4.
Lamers Susanna L, Fogel Gary B, Singer Elyse J, Salemi Marco, Nolan David J, Huysentruyt Leanne C, McGrath Michael S   HIV-1 Nef in macrophage-mediated disease pathogenesis International reviews of immunology, 2012; 31(6): 432-50.
Gelman Benjamin B, Lisinicchia Joshua G, Morgello Susan, Masliah Eliezer, Commins Deborah, Achim Cristian L, Fox Howard S, Kolson Dennis L, Grant Igor, Singer Elyse, Yiannoutsos Constantin T, Sherman Seth, Gensler Gary, Moore David J, Chen Tiansheng, Soukup Vicki M   Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort Journal of acquired immune deficiency syndromes (1999), 2012; .
Soontornniyomkij Virawudh, Moore David J, Gouaux Ben, Soontornniyomkij Benchawanna, Tatro Erick T, Umlauf Anya, Masliah Eliezer, Levine Andrew J, Singer Elyse J, Vinters Harry V, Gelman Benjamin B, Morgello Susan, Cherner Mariana, Grant Igor, Achim Cristian L   Cerebral ?-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ?4 carriers AIDS (London, England), 2012; 26(18): 2327-35.
Levine Andrew J, Service Susan, Miller Eric N, Reynolds Sandra M, Singer Elyse J, Shapshak Paul, Martin Eileen M, Sacktor Ned, Becker James T, Jacobson Lisa P, Thompson Paul, Freimer Nelson   Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2012; 159B(6): 669-83.
Kamat Anupa, Lyons Jennifer L, Misra Vikas, Uno Hajime, Morgello Susan, Singer Elyse J, Gabuzda Dana   Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection Journal of acquired immune deficiency syndromes (1999), 2012; 60(3): 234-43.
Levine Andrew J, Sinsheimer Janet S, Bilder Robert, Shapshak Paul, Singer Elyse J   Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults Journal of clinical and experimental neuropsychology, 2012; 34(1): 78-91.
Dye Richelin V, Miller Karen J, Singer Elyse J, Levine Andrew J   Hormone replacement therapy and risk for neurodegenerative diseases International journal of Alzheimer’s disease, 2012; 2012(4): 258454.
Robinson-Papp Jessica, Gelman Benjamin B, Grant Igor, Singer Elyse, Gensler Gary, Morgello Susan, Morgello Susan   Substance abuse increases the risk of neuropathy in an HIV-infected cohort Muscle & nerve, 2012; 45(4): 471-6.
Gelman Benjamin B, Chen Tiansheng, Lisinicchia Joshua G, Soukup Vicki M, Carmical J Russ, Starkey Jonathan M, Masliah Eliezer, Commins Deborah L, Brandt Dianne, Grant Igor, Singer Elyse J, Levine Andrew J, Miller Jeremy, Winkler Jessica M, Fox Howard S, Luxon Bruce A, Morgello Susan, Morgello Susan   The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment PloS one, 2012; 7(9): e46178.
Sowmya Gopichandran, Shamini Gunasagaran, Anita Sathyanarayanan, Sakharkar Meena, Mathura Venkat, Rodriguez Hector, Levine Andrew J, Singer Elyse, Commins Deborah, Somboonwit Charurut, Sinnott John T, Sidhu Harcharan S, Rajaseger Ganapathy, Pushparaj Peter Natesan, Kangueane Pandajarasamme, Shapshak Paul   HIV-1 envelope accessible surface and polarity: clade, blood, and brain Bioinformation, 2011; 6(2): 48-56.
Lyons Jennifer L, Uno Hajime, Ancuta Petronela, Kamat Anupa, Moore David J, Singer Elyse J, Morgello Susan, Gabuzda Dana   Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection Journal of acquired immune deficiency syndromes (1999), 2011; 57(5): 371-9.
Tate David F, Sampat Mehul, Harezlak Jaroslaw, Fiecas Mark, Hogan Joseph, Dewey Jeffrey, McCaffrey Daniel, Branson Daniel, Russell Troy, Conley Jared, Taylor Michael, Schifitto Giovanni, Schifitto Giavoni, Zhong J, Daar Eric S, Alger Jeffrey, Brown Mark, Singer Elyse, Campbell T, McMahon D, Tso Y, Matesan Janetta, Letendre Scott, Paulose S, Gaugh Michelle, Tripoli C, Yiannoutsos Constantine, Bigler Erin D, Cohen Ronald A, Guttmann Charles R G, Navia Bradford, Navia Bradford   Regional areas and widths of the midsagittal corpus callosum among HIV-infected patients on stable antiretroviral therapies Journal of neurovirology, 2011; 17(4): 368-79.
Harezlak Jarek, Buchthal Steven, Taylor Michael, Schifitto Giovanni, Zhong Jianhui, Daar Eric, Alger Jeffrey, Singer Elyse, Campbell Thomas, Yiannoutsos Constantin, Cohen Ronald, Navia Bradford, Navia Bradford   Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment AIDS (London, England), 2011; 25(5): 625-33.
Thames April D, Becker Brian W, Marcotte Thomas D, Hines Lindsay J, Foley Jessica M, Ramezani Amir, Singer Elyse J, Castellon Steven A, Heaton Robert K, Hinkin Charles H   Depression, cognition, and self-appraisal of functional abilities in HIV: an examination of subjective appraisal versus objective performance The Clinical neuropsychologist, 2011; 25(2): 224-43.
Thames April D, Kim Michelle S, Becker Brian W, Foley Jessica M, Hines Lindsay J, Singer Elyse J, Heaton Robert K, Castellon Steven A, Hinkin Charles H   Medication and finance management among HIV-infected adults: the impact of age and cognition Journal of clinical and experimental neuropsychology, 2011; 33(2): 200-9.
Shapshak Paul, Kangueane Pandjassarame, Fujimura Robert K, Commins Deborah, Chiappelli Francesco, Singer Elyse, Levine Andrew J, Minagar Alireza, Novembre Francis J, Somboonwit Charurut, Nath Avindra, Sinnott John T   Editorial neuroAIDS review AIDS (London, England), 2011; 25(2): 123-41.
Shapshak Paul, Somboonwit Charurut, Sinnott John, Commins Deborah, Singer Elyse, Levine Andrew   Gene-chromosome locations of neuropsychiatric diseases Bioinformation, 2011; 7(7): 366-8.
Shapshak Paul, Duncan Robert, Kangueane Pandajarasamme, Somboonwit Charurut, Sinnott John, Commins Deborah, Singer Elyse, Levine Andrew   HIV associated dementia and HIV encephalitis II: Genes on chromosome 22 expressed in individually microdissected Globus pallidus neurons (Preliminary analysis) Bioinformation, 2011; 6(5): 183-6.
Cohen Ronald A, Harezlak Jaroslaw, Gongvatana Assawin, Buchthal Steven, Schifitto Giovanni, Clark Uraina, Paul Robert, Taylor Michael, Thompson Paul, Tate David, Alger Jeffery, Brown Mark, Zhong Jianhui, Campbell Thomas, Singer Elyse, Daar Eric, McMahon Deborah, Tso Yuen, Yiannoutsos Constantin T, Navia Bradford, Navia Bradford   Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes Journal of neurovirology, 2010; 16(6): 435-44.
Cohen Ronald A, Harezlak Jaroslaw, Schifitto Giovanni, Hana George, Clark Uraina, Gongvatana Assawin, Paul Robert, Taylor Michael, Thompson Paul, Alger Jeffery, Brown Mark, Zhong Jianhui, Campbell Thomas, Singer Elyse, Daar Eric, McMahon Deborah, Tso Yuen, Yiannoutsos Constantin T, Navia Bradford   Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era Journal of neurovirology, 2010; 16(1): 25-32.
Zhao Yu, Navia Bradford A, Marra Christina M, Singer Elyse J, Chang Linda, Berger Joseph, Ellis Ronald J, Kolson Dennis L, Simpson David, Miller Eric N, Lipton Stuart A, Evans Scott R, Schifitto Giovanni, Schifitto Giovanni   Memantine for AIDS dementia complex: open-label report of ACTG 301 HIV clinical trials, 2010; 11(1): 59-67.
Singer Elyse J, Valdes-Sueiras Miguel, Commins Deborah, Levine Andrew   Neurologic presentations of AIDS Neurologic clinics, 2010; 28(1): 253-75.
Levine Andrew J, Singer Elyse J, Sinsheimer Janet S, Hinkin Charles H, Papp Jeanette, Dandekar Sugandha, Giovanelli Allison, Shapshak Paul   CCL3 genotype and current depression increase risk of HIV-associated dementia Neurobehavioral HIV medicine, 2009; 1(1): 1-7.
Kumar Adarsh M, Fernandez J B, Singer Elyse J, Commins Deborah, Waldrop-Valverde Drenna, Ownby Raymond L, Kumar Mahendra   Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains Journal of neurovirology, 2009; 15(3): 257-74.
Micheletti Robert G, Fishbein Gregory A, Fishbein Michael C, Singer Elyse J, Weiss Robert E, Jeffries Robin A, Currier Judith S   Coronary atherosclerotic lesions in human immunodeficiency virus-infected patients: a histopathologic study Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 2009; 18(1): 28-36.
Giunta Brian, Hou Houyan, Zhu Yuyan, Rrapo Elona, Tian Jun, Takashi Mori, Commins Deborah, Singer Elyse, He Johnny, Fernandez Francisco, Tan Jun   HIV-1 Tat contributes to Alzheimer’s disease-like pathology in PSAPP mice International journal of clinical and experimental pathology, 2009; 2(5): 433-43.
Shapshak Paul, Somboonwit Charurut, Drumright Lydia N, Frost Simon D W, Commins Deborah, Tellinghuisen Timothy L, Scott William K, Duncan Robert, McCoy Clyde, Page J Bryan, Giunta Brian, Fernandez Francisco, Singer Elyse, Levine Andrew, Minagar Alireza, Oluwadara Oluwadayo, Kotila Taiwo, Chiappelli Francesco, Sinnott John T   Molecular and contextual markers of hepatitis C virus and drug abuse Molecular diagnosis & therapy, 2009; 13(3): 153-79.
Levine Andrew J, Singer Elyse J, Shapshak Paul   The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders AIDS and behavior, 2009; 13(1): 118-32.
Levine Andrew J, Hinkin Charles H, Ando Kazuhiro, Santangelo Gianni, Martinez Mariana, Valdes-Sueiras Miguel, Saxton Ernestina H, Mathisen Glen, Commins Deborah L, Moe Ardis, Farthing Charles, Singer Elyse J   An exploratory study of long-term neurocognitive outcomes following recovery from opportunistic brain infections in HIV+ adults Journal of clinical and experimental neuropsychology, 2008; 30(7): 836-43.
Fishbein Gregory A, Micheletti Robert G, Currier Judith S, Singer Elyse, Fishbein Michael C   Atherosclerotic oxalosis in coronary arteries Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, 2008; 17(2): 117-23.
Micheletti Robert G, Fishbein Gregory A, Currier Judith S, Singer Elyse J, Fishbein Michael C   Calcification of the internal elastic lamina of coronary arteries Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2008; 21(8): 1019-28.
Fiala Milan, Singer Elyse J, Commins Deborah, Mirzapoiazova Tamara, Verin Alexander, Espinosa Araceli, Ugen Kenneth, Bernas Michael, Witte Marlys, Weinand Martin, Lossinsky Albert S   HIV-1 Antigens in Neurons of Cocaine-Abusing Patients The open virology journal, 2008; 2(1): 24-31.
Ancuta Petronela, Kamat Anupa, Kunstman Kevin J, Kim Eun-Young, Autissier Patrick, Wurcel Alysse, Zaman Tauheed, Stone David, Mefford Megan, Morgello Susan, Singer Elyse J, Wolinsky Steven M, Gabuzda Dana   Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients PloS one, 2008; 3(6): e2516.
Chiappelli Francesco, Shapshak Paul, Commins Deborah, Singer Elyse, Minagar Alireza, Oluwadara Oluwadayo, Prolo Paolo, Pellionisz Andras J   Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications Bioinformation, 2008; 3(1): 47-52.
Shapshak Paul, Chiappelli Francesco, Commins Deborah, Singer Elyse, Levine Andrew J, Somboonwit Charurut, Minagar Alireza, Pellionisz Andras J   Molecular epigenetics, chromatin, and NeuroAIDS/HIV: translational implications Bioinformation, 2008; 3(1): 53-7.
Minagar Alireza, Commins Deborah, Alexander J Steven, Hoque Romy, Chiappelli Francesco, Singer Elyse J, Nikbin Behrooz, Shapshak Paul   NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS Molecular diagnosis & therapy, 2008; 12(1): 25-43.
Hinkin Charles H, Castellon Steven A, Levine Andrew J, Barclay Terry R, Singer Elyse J   Neurocognition in individuals co-infected with HIV and hepatitis C Journal of addictive diseases, 2008; 27(2): 11-7.
Schifitto Giovanni, Navia Bradford A, Yiannoutsos Constantin T, Marra Christina M, Chang Linda, Ernst Thomas, Jarvik Jeffrey G, Miller Eric N, Singer Elyse J, Ellis Ronald J, Kolson Dennis L, Simpson David, Nath Avindra, Berger Joseph, Shriver Sharon L, Millar Linda L, Colquhoun Dodi, Lenkinski Robert, Gonzalez R Gilberto, Lipton Stuart A, Lipton Stuart A, Lipton Stuart A, Lipton Stuart A   Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study AIDS (London, England), 2007; 21(14): 1877-86.
Paul Robert H, Yiannoutsos Constantin T, Miller Eric N, Chang Linda, Marra Christina M, Schifitto Giovanni, Ernst Thomas, Singer Elyse, Richards Todd, Jarvik G Jeffrey, Price Richard, Meyerhoff Dieter J, Kolson Dennis, Ellis Ronald J, Gonzalez Gilberto, Lenkinski Robert E, Cohen Ronald A, Navia Bradford A   Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity The Journal of neuropsychiatry and clinical neurosciences, 2007; 19(3): 283-92.
Rohit Mona, Levine Andrew, Hinkin Charles, Abramyan Shogik, Saxton Ernestine, Valdes-Sueiras Miguel, Singer Elyse   Education correction using years in school or reading grade-level equivalent? Comparing the accuracy of two methods in diagnosing HIV-associated neurocognitive impairment Journal of the International Neuropsychological Society : JINS, 2007; 13(3): 462-70.
Schifitto Giovanni, Yiannoutsos Constantin T, Simpson David M, Marra Christina M, Singer Elyse J, Kolson Dennis L, Nath Avindra, Berger Joseph R, Navia Bradford, Navia Bradford   A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy Journal of neurovirology, 2006; 12(4): 328-31.
Fiala Milan, Eshleman Amy J, Cashman John, Lin Justin, Lossinsky Albert S, Suarez Vannina, Yang Wendy, Zhang Jun, Popik Waldemar, Singer Elyse, Chiappelli Francesco, Carro Eva, Weinand Martin, Witte Marlys, Arthos James   Cocaine increases human immunodeficiency virus type 1 neuroinvasion through remodeling brain microvascular endothelial cells Journal of neurovirology, 2005; 11(3): 281-91.
Woods Steven Paul, Rippeth Julie D, Frol Alan B, Levy Joel K, Ryan Elizabeth, Soukup Vicki M, Hinkin Charles H, Lazzaretto Deborah, Cherner Mariana, Marcotte Thomas D, Gelman Benjamin B, Morgello Susan, Singer Elyse J, Grant Igor, Heaton Robert K   Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV Journal of clinical and experimental neuropsychology, 2004; 26(6): 759-78.
Singer Elyse J   Patient page. A new clue in the mystery of neuro-AIDS Neurology, 2003; 60(12): E12-3.
Singer Elyse J, Aronow H Aaron, Lee Shing-Yi, Hinkin Charles H, Lazarus Tadd   Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive) Journal of clinical microbiology, 2002; 40(10): 3863-4.
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