Posts classified under: Synapses, Cells, and Circuits

Christopher Colwell, Ph.D.

Biography

Christopher S. Colwell is a Neuroscientist who has served on the UCLA School of Medicine faculty since he joined the Department of Psychiatry and Biobehavioral Sciences in 1997. He became a Professor in 2008. Dr. Colwell earned his B.S. in Neuroscience from Vanderbilt University in 1985. During this time, he started his research in circadian rhythms under the mentorship of Dr. T. Page. Dr. Colwell earned his Ph.D. in Biology at the University of Virginia in 1991. His thesis work explored the neural mechanisms by which light regulates circadian rhythms. Dr. Colwell continued this line of research during a postdoctoral fellowship at the University of Virginia with Dr. G. Block. A second postdoctoral fellowship was carried out on the topics of motor control and excitotoxicity in the laboratory of Dr. M. Levine at UCLA. Dr. Colwell learned how to utilize imaging techniques to measure calcium levels inside neurons while a visiting scientist in the laboratory of Dr. Konnerth at the University of Saarland, Germany. Since Dr. Colwell’s faculty appointment at UCLA, his laboratory’s research has focused on understanding the mechanisms underlying circadian rhythms in mammals. Dysfunction in the timing these daily cycles is a key symptom in a number of neurological and psychiatric disorders. Better understanding the basic biology of this timing system should result in new therapies to improve the quality of life of these patients and the people who care for them.

Mark Frye, Ph.D.

Publications

A selected list of publications:

Mongeau Jean-Michel, Frye Mark A   Drosophila Spatiotemporally Integrates Visual Signals to Control Saccades Current biology : CB, 2017; 27(19): 2901-2914.e2.
Frye Mark A   Insect Vision: A Neuron that Anticipates an Object’s Path Current biology : CB, 2017; 27(19): R1076-R1078.
Omoto Jaison Jiro, Keleş Mehmet Fatih, Nguyen Bao-Chau Minh, Bolanos Cheyenne, Lovick Jennifer Kelly, Frye Mark Arthur, Hartenstein Volker   Visual Input to the Drosophila Central Complex by Developmentally and Functionally Distinct Neuronal Populations Current biology : CB, 2017; 27(8): 1098-1110.
Keleş Mehmet F, Frye Mark A   Object-Detecting Neurons in Drosophila Current biology : CB, 2017; 27(5): 680-687.
Keleş Mehmet, Frye Mark A   The eyes have it eLife, 2017; 6(Pt A): 204-213.
Wasserman Sara M, Frye Mark A   Group behavior: social context modulates behavioral responses to sensory stimuli Current biology : CB, 2015; 25(11): R467-9.
Aptekar Jacob W, Keleş Mehmet F, Lu Patrick M, Zolotova Nadezhda M, Frye Mark A   Neurons forming optic glomeruli compute figure-ground discriminations in Drosophila The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015; 35(19): 7587-99.
Frye Mark   Elementary motion detectors Current biology : CB, 2015; 25(6): R215-R217.
Wasserman Sara M, Aptekar Jacob W, Lu Patrick, Nguyen Jade, Wang Austin L, Keles Mehmet F, Grygoruk Anna, Krantz David E, Larsen Camilla, Frye Mark A   Olfactory neuromodulation of motion vision circuitry in Drosophila Current biology : CB, 2015; 25(4): 467-72.
Aptekar Jacob W, Keles Mehmet F, Mongeau Jean-Michel, Lu Patrick M, Frye Mark A, Shoemaker Patrick A   Method and software for using m-sequences to characterize parallel components of higher-order visual tracking behavior in Drosophila Frontiers in neural circuits, 2014; 8(11): 130.
Theobald, JC Frye, MA   Animal Behavior: flying back-to-front, Curr. Biol. , 2008; 18(4): r169.
Chow DM Frye MA   Context dependent olfactory enhanced optomotor flight control in Drosophila, J. Exp. Biol. , 2008; 211: 2478-2485.
Duistermars, BJ Frye, MA   Cross-modal visual input for odor tracking during fly flight, Curr. Biol. , 2008; 18(4): 270-275.
Theobald JC Duistermars BJ Ringach DL Frye MA   Flies see second order motion, Curr. Biol. , 2008; 18(11): r464.
Reynolds, A. Frye, M.A.   Free-flight odor tracking in Drosophila is consistent with a mathematically optimal intermittent scale-free search, PLoS ONE, 2007; 2(4): 354.
Frye, MA   The neuromechanics of fly flight control, Invertebrate Neurobiology, 2007; 209-229.
Duistermars, BJ Chow, D Condro, M Frye, MA   The spatial, temporal, and contrast properties of expansion and rotation flight optomotor responses in Drosophila, J. Exp. Biol. , 2007; 210: 3218-3227.
Frye, MA Dickinson, MH   Visual edge orientation shapes free-flight behavior in Drosophila, Fly, 2007; 3: 153-154.
Humbert, J.S. Frye, M.A.   Extracting behaviorally relevant retinal image motion cues via wide-field integration, Proc. IEEE American Controls Conference, 2006; 2724-2729.
Frye, MA Dickinson, MH   Closing the loop between neurobiology and flight behavior in Drosophila Current opinion in neurobiology. , 2004; 14(6): 729-36.
Frye, MA Dickinson, MH   Fly flight: a model for the neural control of complex behavior Neuron. , 2001; 32(3): 385-8.