Biography
Dr. Miklowitz is Professor of Psychiatry in the Division of Child and Adolescent Psychiatry at the UCLA Semel Institute, and a Senior Clinical Research Fellow in the Department of Psychiatry at Oxford University. He completed his undergraduate work at Brandeis University and his doctoral (1979-1985) and postdoctoral (1985-1988) work at UCLA. His research focuses on family environmental factors and family psychoeducational treatments for adult-onset and childhood-onset bipolar disorder. Dr. Miklowitz received the Joseph Gengerelli Dissertation Award from UCLA (1986), Young Investigator Awards from the International Congress on Schizophrenia Research (1987) and the National Alliance for Research on Schizophrenia and Depression (NARSAD; 1987), a Faculty Research Award (1998) and a Faculty Teaching Award (2008) from the University of Colorado. He won a Distinguished Investigator Award from NARSAD (2001), the 2005 Mogens Schou Award for Research from the International Society for Bipolar Disorders, the 2008 Clinical Researcher of the Year award from Emory University, and the 2008 Monica Fooks Lectureship from Oxford University. He also won the 2009 Gerald L. Klerman Senior Research Investigator Award from the Depressive and Bipolar Support Alliance. He was the 2011 awardee of the Bipolar Mood Disorder Research Award from the Brain and Behavior Research Foundation, and the 2017 Distinguished Investigator awardee from the Society for the Science of Clinical Psychology. Dr. Miklowitz has received multiple grants for his research from the National Institute of Mental Health, the MacArthur Foundation, the American Foundation for Suicide Prevention, the Robert Sutherland Foundation, the Attias Family Foundation, the Deutsch, Kayne, & Knapp Foundations, the Max Gray Foundation, AIM for Mental Health, and the Danny Alberts Foundation. Dr. Miklowitz has published over 300 research articles and 8 books. His book “Bipolar Disorder: A Family-Focused Treatment Approach” (Guilford), won the 1998 Outstanding Research Publication Award from the American Association for Marital and Family Therapy. His book ““The Bipolar Disorder Survival Guide”” is an international best seller in its third edition, with over 275,000 copies in print. His most recent book is co-authored with Michael Gitlin, ““ Clinician’s Guide to Bipolar Disorder: Integrating Pharmacology and Psychotherapy”” (New York: Guilford Press).
Publications
A selected list of publications:
O’Brien Mary P, Miklowitz David J, Candan Kristin A, Marshall Catherine, Domingues Isabel, Walsh Barbara C, Zinberg Jamie L, De Silva Sandra D, Woodberry Kristen A, Cannon Tyrone D
A randomized trial of family focused therapy with populations at clinical high risk for psychosis: effects on interactional behavior Journal of consulting and clinical psychology, 2014; 82(1): 90-101.
Weintraub Marc J, Youngstrom Eric A, Marvin Sarah E, Podell Jennifer L, Walshaw Patricia D, Kim Eunice Y, Suddath Robert L, Forgey-Borlick Marcy J, Matkevich Brittany N, Miklowitz David J
Diagnostic profiles and clinical characteristics of youth referred to a pediatric mood disorders clinic Journal of psychiatric practice, 2014; 20(2): 154-62.
Deckersbach Thilo, Peters Amy T, Sylvia Louisa, Urdahl Anna, Magalhães Pedro V S, Otto Michael W, Frank Ellen, Miklowitz David J, Berk Michael, Kinrys Gustavo, Nierenberg Andrew
Do comorbid anxiety disorders moderate the effects of psychotherapy for bipolar disorder? Results from STEP-BD The American journal of psychiatry, 2014; 171(2): 178-86.
Stange Jonathan P, Sylvia Louisa G, da Silva Magalhães Pedro Vieira, Miklowitz David J, Otto Michael W, Frank Ellen, Berk Michael, Hansen Natasha S, Dougherty Darin D, Nierenberg Andrew A, Deckersbach Thilo
Extreme attributions predict suicidal ideation and suicide attempts in bipolar disorder: prospective data from STEP-BD World psychiatry : official journal of the World Psychiatric Association (WPA), 2014; 13(1): 95-6.
Miklowitz David J, O’Brien Mary P, Schlosser Danielle A, Addington Jean, Candan Kristin A, Marshall Catherine, Domingues Isabel, Walsh Barbara C, Zinberg Jamie L, De Silva Sandra D, Friedman-Yakoobian Michelle, Cannon Tyrone D
Family-focused treatment for adolescents and young adults at high risk for psychosis: results of a randomized trial Journal of the American Academy of Child and Adolescent Psychiatry, 2014; 53(8): 848-58.
Miklowitz David J, Schneck Christopher D, Birmaher Boris, Delbello Melissa P, Axelson David A
Response to Parikh The American journal of psychiatry, 2014; 171(12): 1335-6.
Sylvia Louisa G, Hay Aleena, Ostacher Michael J, Miklowitz David J, Nierenberg Andrew A, Thase Michael E, Sachs Gary S, Deckersbach Thilo, Perlis Roy H
Association between therapeutic alliance, care satisfaction, and pharmacological adherence in bipolar disorder Journal of clinical psychopharmacology, 2013; 33(3): 343-50.
Miklowitz David J, Schneck Christopher D, Singh Manpreet K, Taylor Dawn O, George Elizabeth L, Cosgrove Victoria E, Howe Meghan E, Dickinson L Miriam, Garber Judy, Chang Kiki D
Early intervention for symptomatic youth at risk for bipolar disorder: a randomized trial of family-focused therapy Journal of the American Academy of Child and Adolescent Psychiatry, 2013; 52(2): 121-31.
Miklowitz David J, Price Jonathan, Holmes Emily A, Rendell Jennifer, Bell Sarah, Budge Katie, Christensen Jean, Wallace Joshua, Simon Judit, Armstrong Neil M, McPeake Lily, Goodwin Guy M, Geddes John R
Facilitated Integrated Mood Management for adults with bipolar disorder Bipolar disorders, 2012; 14(2): 185-97.
Perlick, D. A., Gonzalez, J., Huth, M., Culver, J., Michael, L., Kaczynski, R., Calabrese, J., & Miklowitz, D. J. Rumination, gender and depressive symptoms associated with caregiving strain in bipolar disorder, Acta Psychiatrica Scandinavaca, 2012; 126(5): 356-362.
Fan Jinbo, Ionita-Laza Iuliana, McQueen Matthew B, Devlin Bernie, Purcell Shaun, Faraone Stephen V, Allen Michael H, Bowden Charles L, Calabrese Joseph R, Fossey Mark D, Friedman Edward S, Gyulai Laszlo, Hauser Peter, Ketter Terence B, Marangell Lauren B, Miklowitz David J, Nierenberg Andrew A, Patel Jayendra K, Sachs Gary S, Thase Michael E, Molay Francine B, Escamilla Michael A, Nimgaonkar Vishwajit L, Sklar Pamela, Laird Nan M, Smoller Jordan W
Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2010; 153B(1): 29-37.
Perlis Roy H, Ostacher Michael J, Goldberg Joseph F, Miklowitz David J, Friedman Edward, Calabrese Joseph, Thase Michael E, Sachs Gary S
Transition to mania during treatment of bipolar depression Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010; 35(13): 2545-52.
Mansour Hader A, Talkowski Michael E, Wood Joel, Chowdari Kodavali V, McClain Lora, Prasad Konasale, Montrose Debra, Fagiolini Andrea, Friedman Edward S, Allen Michael H, Bowden Charles L, Calabrese Joseph, El-Mallakh Rif S, Escamilla Michael, Faraone Stephen V, Fossey Mark D, Gyulai Laszlo, Loftis Jennifer M, Hauser Peter, Ketter Terence A, Marangell Lauren B, Miklowitz David J, Nierenberg Andrew A, Patel Jayendra, Sachs Gary S, Sklar Pamela, Smoller Jordan W, Laird Nan, Keshavan Matcheri, Thase Michael E, Axelson David, Birmaher Boris, Lewis David, Monk Tim, Frank Ellen, Kupfer David J, Devlin Bernie, Nimgaonkar Vishwajit L
Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia Bipolar disorders, 2009; 11(7): 701-10.
Goldberg Joseph F, Brooks John O, Kurita Keiko, Hoblyn Jennifer C, Ghaemi S Nassir, Perlis Roy H, Miklowitz David J, Ketter Terence A, Sachs Gary S, Thase Michael E
Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD The Journal of clinical psychiatry, 2009; 70(2): 155-62.
Goldberg Joseph F, Perlis Roy H, Bowden Charles L, Thase Michael E, Miklowitz David J, Marangell Lauren B, Calabrese Joseph R, Nierenberg Andrew A, Sachs Gary S
Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD The American journal of psychiatry, 2009; 166(2): 173-81.
Perlis Roy H, Dennehy Ellen B, Miklowitz David J, Delbello Melissa P, Ostacher Michael, Calabrese Joseph R, Ametrano Rebecca M, Wisniewski Stephen R, Bowden Charles L, Thase Michael E, Nierenberg Andrew A, Sachs Gary
Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study Bipolar disorders, 2009; 11(4): 391-400.
Chessick Cheryl A, Perlick Deborah A, Miklowitz David J, Dickinson L Miriam, Allen Michael H, Morris Chad D, Gonzalez Jodi M, Marangell Lauren B, Cosgrove Victoria, Ostacher Michael, Ostacher Michael
Suicidal ideation and depressive symptoms among bipolar patients as predictors of the health and well-being of caregivers Bipolar disorders, 2009; 11(8): 876-84.
Perlick Deborah A, Rosenheck Robert A, Miklowitz David J, Kaczynski Richard, Link Bruce, Ketter Terence, Wisniewski Stephen, Wolff Nancy, Sachs Gary, Sachs Gary
Caregiver burden and health in bipolar disorder: a cluster analytic approach The Journal of nervous and mental disease, 2008; 196(6): 484-91.
Gyulai Laszlo, Bauer Mark S, Marangell Lauren B, Dennehy Ellen B, Thase Michael E, Otto Michael W, Zhang Hongwei, Wisniewski Stephen R, Miklowitz David J, Rapaport Mark H, Baldassano Claudia F, Sachs Gary S, Sachs Gary S
Correlates of functioning in bipolar disorder Psychopharmacology bulletin, 2008; 41(4): 51-64.
Miklowitz David J, Axelson David A, Birmaher Boris, George Elizabeth L, Taylor Dawn O, Schneck Christopher D, Beresford Carol A, Dickinson L Miriam, Craighead W Edward, Brent David A
Family-focused treatment for adolescents with bipolar disorder: results of a 2-year randomized trial Archives of general psychiatry, 2008; 65(9): 1053-61.
Sachs Gary S, Nierenberg Andrew A, Calabrese Joseph R, Marangell Lauren B, Wisniewski Stephen R, Gyulai Laszlo, Friedman Edward S, Bowden Charles L, Fossey Mark D, Ostacher Michael J, Ketter Terence A, Patel Jayendra, Hauser Peter, Rapport Daniel, Martinez James M, Allen Michael H, Miklowitz David J, Otto Michael W, Dennehy Ellen B, Thase Michael E
Effectiveness of adjunctive antidepressant treatment for bipolar depression The New England journal of medicine, 2007; 356(17): 1711-22.
Gonzalez Jodi M, Perlick Deborah A, Miklowitz David J, Kaczynski Richard, Hernandez Melissa, Rosenheck Robert A, Culver Jenifer L, Ostacher Michael J, Bowden Charles L, Bowden Charles L
Factors associated with stigma among caregivers of patients with bipolar disorder in the STEP-BD study Psychiatric services (Washington, D.C.), 2007; 58(1): 41-8.
Miklowitz David J, Otto Michael W, Frank Ellen, Reilly-Harrington Noreen A, Kogan Jane N, Sachs Gary S, Thase Michael E, Calabrese Joseph R, Marangell Lauren B, Ostacher Michael J, Patel Jayendra, Thomas Marshall R, Araga Mako, Gonzalez Jodi M, Wisniewski Stephen R
Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial The American journal of psychiatry, 2007; 164(9): 1340-7.
Perlick Deborah A, Rosenheck Robert A, Miklowitz David J, Chessick Cheryl, Wolff Nancy, Kaczynski Richard, Ostacher Michael, Patel Jayendra, Desai Rani, Desai Rani
Prevalence and correlates of burden among caregivers of patients with bipolar disorder enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder Bipolar disorders, 2007; 9(3): 262-73.
Miklowitz David J, Otto Michael W, Frank Ellen, Reilly-Harrington Noreen A, Wisniewski Stephen R, Kogan Jane N, Nierenberg Andrew A, Calabrese Joseph R, Marangell Lauren B, Gyulai Laszlo, Araga Mako, Gonzalez Jodi M, Shirley Edwin R, Thase Michael E, Sachs Gary S
Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program Archives of general psychiatry, 2007; 64(4): 419-26.
Gonzalez Jodi M, Thompson Peter, Escamilla Michael, Araga Mako, Singh Vivek, Farrelly Niamh, Thase Michael E, Miklowitz David J, Bowden Charles L
Treatment characteristics and illness burden among European Americans, African Americans, and Latinos in the first 2,000 patients of the systematic treatment enhancement program for bipolar disorder Psychopharmacology bulletin, 2007; 40(1): 31-46.
Perlis Roy H, Ostacher Michael J, Patel Jayendra K, Marangell Lauren B, Zhang Hongwei, Wisniewski Stephen R, Ketter Terence A, Miklowitz David J, Otto Michael W, Gyulai Laszlo, Reilly-Harrington Noreen A, Nierenberg Andrew A, Sachs Gary S, Thase Michael E
Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) The American journal of psychiatry, 2006; 163(2): 217-24.
Marangell Lauren B, Bauer Mark S, Dennehy Ellen B, Wisniewski Stephen R, Allen Michael H, Miklowitz David J, Oquendo Maria A, Frank Ellen, Perlis Roy H, Martinez James M, Fagiolini Andrea, Otto Michael W, Chessick Cheryl A, Zboyan Holly A, Miyahara Sachiko, Sachs Gary, Thase Michael E
Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 years Bipolar disorders, 2006; 8(5 Pt 2): 566-75.
Miklowitz David J, Otto Michael W, Wisniewski Stephen R, Araga Mako, Frank Ellen, Reilly-Harrington Noreen A, Lembke Anna, Sachs Gary S
Psychotherapy, symptom outcomes, and role functioning over one year among patients with bipolar disorder Psychiatric services (Washington, D.C.), 2006; 57(7): 959-65.
Nierenberg Andrew A, Ostacher Michael J, Calabrese Joseph R, Ketter Terence A, Marangell Lauren B, Miklowitz David J, Miyahara Sachiko, Bauer Mark S, Thase Michael E, Wisniewski Stephen R, Sachs Gary S
Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone The American journal of psychiatry, 2006; 163(2): 210-6.
Fossey Mark D, Otto Michael W, Yates William R, Wisniewski Steve R, Gyulai Laszlo, Allen Michael H, Miklowitz David J, Coon Kim A, Ostacher Michael J, Neel Jackie L, Thase Michael E, Sachs Gary S, Weiss Roger D, Weiss Roger D
Validity of the distinction between primary and secondary substance use disorder in patients with bipolar disorder: data from the first 1000 STEP-BD participants The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, 2006; 15(2): 138-43.
Allen Michael H, Chessick Cheryl A, Miklowitz David J, Goldberg Joseph F, Wisniewski Stephen R, Miyahara Sachiko, Calabrese Joseph R, Marangell Lauren, Bauer Mark S, Thomas Marshall R, Bowden Charles L, Sachs Gary S
Contributors to suicidal ideation among bipolar patients with and without a history of suicide attempts Suicide & life-threatening behavior, 2005; 35(6): 671-80.
Mansour Hader A, Talkowski Michael E, Wood Joel, Pless Lora, Bamne Mikhil, Chowdari Kodavali V, Allen Michael, Bowden Charles L, Calabrese Joseph, El-Mallakh Rif S, Fagiolini Andrea, Faraone Stephen V, Fossey Mark D, Friedman Edward S, Gyulai Laszlo, Hauser Peter, Ketter Terence A, Loftis Jennifer M, Marangell Lauren B, Miklowitz David J, Nierenberg Andrew A, Patel Jayendra, Sachs Gary S, Sklar Pamela, Smoller Jordan W, Thase Michael E, Frank Ellen, Kupfer David J, Nimgaonkar Vishwajit L
Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter Annals of medicine, 2005; 37(8): 590-602.
Kogan Jane N, Otto Michael W, Bauer Mark S, Dennehy Ellen B, Miklowitz David J, Zhang Hong-Wei, Ketter Terence, Rudorfer Matthew V, Wisniewski Stephen R, Thase Michael E, Calabrese Joseph, Sachs Gary S, Sachs Gary S
Demographic and diagnostic characteristics of the first 1000 patients enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Bipolar disorders, 2004; 6(6): 460-9.
Marangell Lauren B, Martinez James M, Ketter Terence A, Bowden Charles L, Goldberg Joseph F, Calabrese Joseph R, Miyahara Sachiko, Miklowitz David J, Sachs Gary S, Thase Michael E, Thase Michael E
Lamotrigine treatment of bipolar disorder: data from the first 500 patients in STEP-BD Bipolar disorders, 2004; 6(2): 139-43.
Schneck Christopher D, Miklowitz David J, Calabrese Joseph R, Allen Michael H, Thomas Marshall R, Wisniewski Stephen R, Miyahara Sachiko, Shelton Melvin D, Ketter Terence A, Goldberg Joseph F, Bowden Charles L, Sachs Gary S
Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the Systematic Treatment Enhancement Program The American journal of psychiatry, 2004; 161(10): 1902-8.
Hollon Steven D, Muñoz Ricardo F, Barlow David H, Beardslee William R, Bell Carl C, Bernal Guillermo, Clarke Gregory N, Franciosi L Patt, Kazdin Alan E, Kohn Laura, Linehan Marsha M, Markowitz John C, Miklowitz David J, Persons Jacqueline B, Niederehe George, Sommers David
Psychosocial intervention development for the prevention and treatment of depression: promoting innovation and increasing access Biological psychiatry, 2002; 52(6): 610-30.