Denson Fujikawa, M.D.
VA GLAHS
Mail code 151B4
16111 Plummer Street
North Hills, CA 91343
UNITED STATES
Work Address:
Office
16111 Plummer Street
North Hills, CA 91343
UNITED STATES
Laboratory
Sepulveda VA ACC
16111 Plummer Street
North Hills, CA 91343
UNITED STATES
Biography
Denson G. Fujikawa is a neurologist and neuroscientist who has been a member of the UCLA faculty since he joined the Department of Neurology in as a clinical instructor in 1981. Dr. Fujikawa is at the Sepulveda VA Ambulatory Care Center. He became an Adjunct Professor in 1996, and has been a Staff Neurologist at Sepulveda since 1983. Dr. Fujikawa earned his A.B. degree magna cum laude in psychology at Harvard University, and his M.D. degree at the University of Southern California School of Medicine. He did two years of general surgery residency at Columbia-Presbyterian Medical Center in New York, two years of of neurosurgery residency at UCLA Medical Center, then switched to neurology, completing his residency at Harbor-UCLA Medical Center in 1981. He then spent two years as a research fellow in Dr. Claude Wasterlain’s Epilepsy Research Laboratory at Sepulveda. He spends half his time in clinical neurology, training UCLA neurology residents, with a subspecialty interest in epilepsy, and half his time doing basic research on in vivo mechanisms of naturally occurring apoptotic and pathologically induced necrotic neuronal death.
Publications
- Engel J, Moshé SL, Nehlig A, Fujikawa DG, Sankar R, Naylor DE, Mazarati AM, Wasterlain CG. Introduction to the special issue on status epilepticus: neuronal injury, plasticity, and therapies; Celebrating the legacy of Dr. Claude G. Wasterlain.. Epilepsia open, 2023.
- Fujikawa DG. Programmed mechanisms of status epilepticus-induced neuronal necrosis.. Epilepsia open, 2022.
- Fujikawa DG. Starting ketamine for neuroprotection earlier than its current use as an anesthetic/antiepileptic drug late in refractory status epilepticus.. Epilepsia, 2019.
- Fujikawa DG, Pais ES, Aviles ER, Hsieh KC, Bashir MT. Methamphetamine-induced neuronal necrosis: the role of electrographic seizure discharges.. Neurotoxicology, 2015.
- Fujikawa DG. The role of excitotoxic programmed necrosis in acute brain injury.. Computational and structural biotechnology journal, 2015.
- Fujikawa DG, Licht EA, Jacobsen RH. Chronic epileptic encephalopathy in adult patients with bilaterally synchronous frequent and/or prolonged subclinical epileptiform discharges.. Epilepsy & behavior : E&B, 2012.
- Zhao S, Aviles ER, Fujikawa DG. Nuclear translocation of mitochondrial cytochrome c, lysosomal cathepsins B and D, and three other death-promoting proteins within the first 60 minutes of generalized seizures.. Journal of neuroscience research, 2010.
- Fujikawa DG, Zhao S, Ke X, Shinmei SS, Allen SG. Mild as well as severe insults produce necrotic, not apoptotic, cells: evidence from 60-min seizures.. Neuroscience letters, 2009.
- Fujikawa DG, Shinmei SS, Zhao S, Aviles ER. Caspase-dependent programmed cell death pathways are not activated in generalized seizure-induced neuronal death.. Brain research, 2007.
- Fujikawa DG. Prolonged seizures and cellular injury: understanding the connection.. Epilepsy & behavior : E&B, 2005.
- Walker M, Cross H, Smith S, Young C, Aicardi J, Appleton R, Aylett S, Besag F, Cock H, DeLorenzo R, Drislane F, Duncan J, Ferrie C, Fujikawa D, Gray W, Kaplan P, Koutroumanidis M, O'Regan M, Plouin P, Sander J, Scott R, Shorvon S, Treiman D, Wasterlain C, Wieshmann U. Nonconvulsive status epilepticus: Epilepsy Research Foundation workshop reports.. Epileptic disorders : international epilepsy journal with videotape, 2005.
- Fujikawa DG. Neuronal death in mesial temporal sclerosis: separating morphology from mechanism.. Epilepsia, 2003.
- Niquet J, Baldwin RA, Allen SG, Fujikawa DG, Wasterlain CG. Hypoxic neuronal necrosis: protein synthesis-independent activation of a cell death program.. Proceedings of the National Academy of Sciences of the United States of America, 2003.
- Wu A, Fujikawa DG. Effects of AMPA-receptor and voltage-sensitive sodium channel blockade on high potassium-induced glutamate release and neuronal death in vivo.. Brain research, 2002.
- Fujikawa DG. Apoptosis: ignoring morphology and focusing on biochemical mechanisms will not eliminate confusion.. Trends in pharmacological sciences, 2002.
- Licht EA, Jacobsen RH, Fujikawa DG. Chronically Impaired Frontal Lobe Function from Subclinical Epileptiform Discharges.. Epilepsy & behavior : E&B, 2002.