Gary Small, M.D.

gsmall@mednet.ucla.edu

Faculty Member

Professor
Director, UCLA Longevity Center
Department of Psychiatry & Biobehavioral Sciences
David Geffen School of Medicine
University of California, Los Angeles

760 Westwood Plaza
Los Angeles, CA 90024
UNITED STATES

Publications

Thana-Udom K, Siddarth P, Miller KJ, Dunkin JJ, Small GW, Ercoli LM. The Effect of Memory Training on Memory Control Beliefs in Older Adults with Subjective Memory Complaints.. Experimental aging research, 2020.
Yang J, Guo Y, Lee R, Henning SM, Wang J, Pan Y, Qing T, Hsu M, Nguyen A, Prabha S, Ojha R, Small GW, Heber D, Li Z. Pomegranate Metabolites Impact Tryptophan Metabolism in Humans and Mice.. Current developments in nutrition, 2020.
Siddarth P, Thana-Udom K, Ojha R, Merrill D, Dzierzewski JM, Miller K, Small GW, Ercoli L. Sleep quality, neurocognitive performance, and memory self-appraisal in middle-aged and older adults with memory complaints.. International psychogeriatrics, 2020.
Hossain A, Small G, Crean AM, Jones R, Yam Y, Bishop H, Chow BJW. Prognostic value of coronary computed tomography angiography in patients with prior percutaneous coronary intervention.. Journal of cardiovascular computed tomography, 2020.
Small GW. Managing the Burden of Dementia Related Delusions and Hallucinations.. The Journal of family practice, 2020.
Small GW, Lee J, Kaufman A, Jalil J, Siddarth P, Gaddipati H, Moody TD, Bookheimer SY. Brain health consequences of digital technology use .. Dialogues in clinical neuroscience, 2020.
Krause-Sorio B, Siddarth P, Laird KT, Ercoli L, Narr K, Barrio JR, Small G, Lavretsky H. [18F]FDDNP PET binding predicts change in executive function in a pilot clinical trial of geriatric depression.. International psychogeriatrics, 2020.
Siddarth P, Li Z, Miller KJ, Ercoli LM, Merril DA, Henning SM, Heber D, Small GW. Randomized placebo-controlled study of the memory effects of pomegranate juice in middle-aged and older adults.. The American journal of clinical nutrition, 2020.
Torres-Acosta N, O'Keefe JH, O'Keefe EL, Isaacson R, Small G. Therapeutic Potential of TNF-α Inhibition for Alzheimer's Disease Prevention.. Journal of Alzheimer's disease : JAD, 2020.
Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, Bennett DA, Gearing M, Juncos JL, Kramer J, Lee SE, Yokoyama JS, Mendez MF, Chui H, Zarow C, Ringman JM, Kilic U, Babacan-Yildiz G, Levey A, DeCarli CS, Cotman CW, Boxer AL, Miller BL, Coppola G. Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.. Alzheimer disease and associated disorders, 2019.
Saxena PP, Small GW. Invited Perspective on "A Comparison of Long-Acting Injectable Antipsychotics With Oral Antipsychotics on Time to Rehospitalization Within One Year of Discharge in Elderly Patients With Schizophrenia".. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019.
McDonnell M, Dill L, Panos S, Amano S, Brown W, Giurgius S, Small G, Miller K. Verbal fluency as a screening tool for mild cognitive impairment.. International psychogeriatrics, 2019.
Cole GB, Satyamurthy N, Liu J, Wong KP, Small GW, Huang SC, Košmrlj J, Barrio JR, Petric A. The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET.. Molecular imaging and biology, 2019.
Chen ST, Volle D, Jalil J, Wu P, Small GW. Health-Promoting Strategies for the Aging Brain.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2018.
Burggren AC, Siddarth P, Mahmood Z, London ED, Harrison TM, Merrill DA, Small GW, Bookheimer SY. Subregional Hippocampal Thickness Abnormalities in Older Adults with a History of Heavy Cannabis Use.. Cannabis and cannabinoid research, 2018.
Siddarth P, Burggren AC, Merrill DA, Ercoli LM, Mahmood Z, Barrio JR, Small GW. Longer TOMM40 poly-T variants associated with higher FDDNP-PET medial temporal tau and amyloid binding.. PloS one, 2018.
Siddarth P, Burggren AC, Eyre HA, Small GW, Merrill DA. Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults.. PloS one, 2018.
Siddarth P, Barrio JR, Small GW. Response to Letter About Memory and Brain Effects of Curcumin.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2018.
Chen ST, Siddarth P, Merrill DA, Martinez J, Emerson ND, Liu J, Wong KP, Satyamurthy N, Giza CC, Huang SC, Fitzsimmons RP, Bailes J, Omalu B, Barrio JR, Small GW. FDDNP-PET Tau Brain Protein Binding Patterns in Military Personnel with Suspected Chronic Traumatic Encephalopathy1.. Journal of Alzheimer's disease : JAD, 2018.
Siddarth P, Rahi B, Emerson ND, Burggren AC, Miller KJ, Bookheimer S, Lavretsky H, Dobkin B, Small G, Merrill DA. Physical Activity and Hippocampal Sub-Region Structure in Older Adults with Memory Complaints.. Journal of Alzheimer's disease : JAD, 2018.
McEwen SC, Siddarth P, Rahi B, Kim Y, Mui W, Wu P, Emerson ND, Lee J, Greenberg S, Shelton T, Kaiser S, Small GW, Merrill DA. Simultaneous Aerobic Exercise and Memory Training Program in Older Adults with Subjective Memory Impairments.. Journal of Alzheimer's disease : JAD, 2018.
Small GW, Siddarth P, Li Z, Miller KJ, Ercoli L, Emerson ND, Martinez J, Wong KP, Liu J, Merrill DA, Chen ST, Henning SM, Satyamurthy N, Huang SC, Heber D, Barrio JR. Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017.
Roussotte FF, Siddarth P, Merrill DA, Narr KL, Ercoli LM, Martinez J, Emerson ND, Barrio JR, Small GW. In Vivo Brain Plaque and Tangle Burden Mediates the Association Between Diastolic Blood Pressure and Cognitive Functioning in Nondemented Adults.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017.
Roussotte FF, Hua X, Narr KL, Small GW, Thompson PM, Alzheimer's Disease Neuroimaging Initiative . The C677T variant in MTHFR modulates associations between brain integrity, mood, and cognitive functioning in old age.. Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017.
Burggren AC, Mahmood Z, Harrison TM, Siddarth P, Miller KJ, Small GW, Merrill DA, Bookheimer SY. Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2017.
Eyre HA, Siddarth P, van Dyk K, St Cyr N, Baune BT, Barrio JR, Small GW, Lavretsky H. Neural correlates of apathy in late-life depression: a pilot [18 F]FDDNP positron emission tomography study.. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017.
Doran E, Keator D, Head E, Phelan MJ, Kim R, Totoiu M, Barrio JR, Small GW, Potkin SG, Lott IT. Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.. Journal of Alzheimer's disease : JAD, 2017.
Small GW. Detection and Prevention of Cognitive Decline.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016.
Roussotte FF, Narr KL, Small GW, Thompson PM, Alzheimer’s Disease Neuroimaging Initiative . The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration.. Neuroreport, 2016.
Raji CA, Merrill DA, Barrio JR, Omalu B, Small GW. Progressive Focal Gray Matter Volume Loss in a Former High School Football Player: A Possible Magnetic Resonance Imaging Volumetric Signature for Chronic Traumatic Encephalopathy.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016.
Harrison TM, Mahmood Z, Lau EP, Karacozoff AM, Burggren AC, Small GW, Bookheimer SY. An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.. eNeuro, 2016.
Merrill DA, Siddarth P, Raji CA, Emerson ND, Rueda F, Ercoli LM, Miller KJ, Lavretsky H, Harris LM, Burggren AC, Bookheimer SY, Barrio JR, Small GW. Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016.
Eyre HA, Lavretsky H, Forbes M, Raji C, Small G, McGorry P, Baune BT, Reynolds C. Convergence Science Arrives: How Does It Relate to Psychiatry?. Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 2016.
Lavretsky H, Small GW. Introduction.. The Journal of clinical psychiatry, 2016.
Harrison TM, Burggren AC, Small GW, Bookheimer SY. Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease.. Human brain mapping, 2015.
Small GW, Greenfield S. Current and Future Treatments for Alzheimer Disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2015.
Barrio JR, Small GW, Wong KP, Huang SC, Liu J, Merrill DA, Giza CC, Fitzsimmons RP, Omalu B, Bailes J, Kepe V. In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging.. Proceedings of the National Academy of Sciences of the United States of America, 2015.
Chow BJ, Small G, Yam Y, Chen L, McPherson R, Achenbach S, Al-Mallah M, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Cheng VY, Chinnaiyan K, Cury R, Delago A, Dunning A, Feuchtner G, Hadamitzky M, Hausleiter J, Karlsberg RP, Kaufmann PA, Kim YJ, Leipsic J, LaBounty T, Lin F, Maffei E, Raff GL, Shaw LJ, Villines TC, Min JK, CONFIRM Investigators . Prognostic and therapeutic implications of statin and aspirin therapy in individuals with nonobstructive coronary artery disease: results from the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter registry) registry.. Arteriosclerosis, thrombosis, and vascular biology, 2015.
Baerresen KM, Miller KJ, Hanson ER, Miller JS, Dye RV, Hartman RE, Vermeersch D, Small GW. Neuropsychological tests for predicting cognitive decline in older adults.. Neurodegenerative disease management, 2015.
Ye H, Wong KP, Wardak M, Dahlbom M, Kepe V, Barrio JR, Nelson LD, Small GW, Huang SC. Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data.. PloS one, 2014.
Chen ST, Siddarth P, Ercoli LM, Merrill DA, Torres-Gil F, Small GW. Modifiable risk factors for Alzheimer disease and subjective memory impairment across age groups.. PloS one, 2014.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-o M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L. Life extension factor klotho enhances cognition.. Cell reports, 2014.
Small GW. Treating dementia and agitation.. JAMA, 2014.
Murdock DG, Bradford Y, Schnetz-Boutaud N, Mayo P, Allen MJ, D'Aoust LN, Liang X, Mitchell SL, Zuchner S, Small GW, Gilbert JR, Pericak-Vance MA, Haines JL. KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.. PloS one, 2013.
Tran T, Small G, Cocker M, Yam Y, Chow BJ. A single slice measure of epicardial adipose tissue can serve as an indirect measure of total epicardial adipose tissue burden and is associated with obstructive coronary artery disease.. European heart journal cardiovascular Imaging, 2013.
Donix M, Burggren AC, Scharf M, Marschner K, Suthana NA, Siddarth P, Krupa AK, Jones M, Martin-Harris L, Ercoli LM, Miller KJ, Werner A, von Kummer R, Sauer C, Small GW, Holthoff VA, Bookheimer SY. APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease.. Psychiatry research, 2013.
Bookheimer SY, Renner BA, Ekstrom A, Li Z, Henning SM, Brown JA, Jones M, Moody T, Small GW. Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints.. Evidence-based complementary and alternative medicine : eCAM, 2013.
Chen ST, Siddarth P, Saito NY, Rueda F, Haight T, Ercoli LM, Miller KJ, Lavretsky H, Barrio JR, Bookheimer SY, Small GW, Merrill DA. Psychological well-being and regional brain amyloid and tau in mild cognitive impairment.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013.
Small GW, Siddarth P, Ercoli LM, Chen ST, Merrill DA, Torres-Gil F. Healthy behavior and memory self-reports in young, middle-aged, and older adults.. International psychogeriatrics, 2013.
Small GW. Geriatric Psychiatry Fellowship Recruitment: Crisis or Opportunity?. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013.
Small GW, Kepe V, Siddarth P, Ercoli LM, Merrill DA, Donoghue N, Bookheimer SY, Martinez J, Omalu B, Bailes J, Barrio JR. PET scanning of brain tau in retired national football league players: preliminary findings.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013.
Kepe V, Bordelon Y, Boxer A, Huang SC, Liu J, Thiede FC, Mazziotta JC, Mendez MF, Donoghue N, Small GW, Barrio JR. PET imaging of neuropathology in tauopathies: progressive supranuclear palsy.. Journal of Alzheimer's disease : JAD, 2013.
Smid LM, Kepe V, Vinters HV, Bresjanac M, Toyokuni T, Satyamurthy N, Wong KP, Huang SC, Silverman DH, Miller K, Small GW, Barrio JR. Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.. Journal of Alzheimer's disease : JAD, 2013.
Merrill DA, Siddarth P, Kepe V, Raja PV, Saito N, Ercoli LM, Miller KJ, Lavretsky H, Bookheimer SY, Barrio JR, Small GW. Vascular risk and FDDNP-PET influence cognitive performance.. Journal of Alzheimer's disease : JAD, 2013.
Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE, Lang R, Beecham G, Martin ER, Gilbert J, Benatar M, Small GW, Mash D, Byrd G, Haines JL, Pericak-Vance MA, Züchner S. Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians.. Neurobiology of aging, 2012.
Small GW, Komo S, La Rue A, Kaplan A, Mandelkern MA. Memory Self-Appraisal and Cerebral Glucose Metabolism in Age-Associated Memory Impairment.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012.
Donix M, Ercoli LM, Siddarth P, Brown JA, Martin-Harris L, Burggren AC, Miller KJ, Small GW, Bookheimer SY. Influence of Alzheimer disease family history and genetic risk on cognitive performance in healthy middle-aged and older people.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012.
Miller KJ, Siddarth P, Gaines JM, Parrish JM, Ercoli LM, Marx K, Ronch J, Pilgram B, Burke K, Barczak N, Babcock B, Small GW. The memory fitness program: cognitive effects of a healthy aging intervention.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012.
Wilks MQ, Protas H, Wardak M, Kepe V, Small GW, Barrio JR, Huang SC. Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients.. International journal of Alzheimer's disease, 2012.
Protas HD, Kepe V, Hayashi KM, Klunder AD, Braskie MN, Ercoli L, Siddarth P, Bookheimer SY, Thompson PM, Small GW, Barrio JR, Huang SC. Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET.. NeuroImage, 2012.
Donix M, Small GW, Bookheimer SY. Family history and APOE-4 genetic risk in Alzheimer's disease.. Neuropsychology review, 2012.
Merrill DA, Siddarth P, Saito NY, Ercoli LM, Burggren AC, Kepe V, Lavretsky H, Miller KJ, Kim J, Huang SC, Bookheimer SY, Barrio JR, Small GW. Self-reported memory impairment and brain PET of amyloid and tau in middle-aged and older adults without dementia.. International psychogeriatrics, 2012.
Curiel AR, Miller KJ, Pollard K, Kim J, Kravitz J, Small GW. Anxiety and verbal memory performance in APOE-4 carriers and noncarriers aged 50 years and above.. Aging health, 2012.
Small GW, Siddarth P, Kepe V, Ercoli LM, Burggren AC, Bookheimer SY, Miller KJ, Kim J, Lavretsky H, Huang SC, Barrio JR. Prediction of cognitive decline by positron emission tomography of brain amyloid and tau.. Archives of neurology, 2012.
Lee GJ, Curiel AR, Miller KJ, Amano S, Gorsuch R, Small GW. Language performance in postmenopausal women with and without hormone therapy and men.. Aging health, 2012.
Wong KP, Kepe V, Dahlbom M, Satyamurthy N, Small GW, Barrio JR, Huang SC. Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F]FDDNP PET determinations.. NeuroImage, 2011.
Brown JA, Terashima KH, Burggren AC, Ercoli LM, Miller KJ, Small GW, Bookheimer SY. Brain network local interconnectivity loss in aging APOE-4 allele carriers.. Proceedings of the National Academy of Sciences of the United States of America, 2011.
Kumar A, Kepe V, Barrio JR, Siddarth P, Manoukian V, Elderkin-Thompson V, Small GW. Protein binding in patients with late-life depression.. Archives of general psychiatry, 2011.
Nelson LD, Siddarth P, Kepe V, Scheibel KE, Huang SC, Barrio JR, Small GW. Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome.. Archives of neurology, 2011.
Teng E, Kepe V, Frautschy SA, Liu J, Satyamurthy N, Yang F, Chen PP, Cole GB, Jones MR, Huang SC, Flood DG, Trusko SP, Small GW, Cole GM, Barrio JR. [F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.. Neurobiology of disease, 2011.
Shin J, Kepe V, Small GW, Phelps ME, Barrio JR. Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network.. International journal of Alzheimer's disease, 2011.
Shin J, Kepe V, Barrio JR, Small GW. The merits of FDDNP-PET imaging in Alzheimer's disease.. Journal of Alzheimer's disease : JAD, 2011.
Merrill DA, Small GW. Prevention in psychiatry: effects of healthy lifestyle on cognition.. The Psychiatric clinics of North America, 2010.
Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, Goate AM, Bird TD, Leverenz JB. Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation.. Neuroscience letters, 2010.
Small G, Bullock R. Defining optimal treatment with cholinesterase inhibitors in Alzheimer's disease.. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2010.
Donix M, Burggren AC, Suthana NA, Siddarth P, Ekstrom AD, Krupa AK, Jones M, Martin-Harris L, Ercoli LM, Miller KJ, Small GW, Bookheimer SY. Family history of Alzheimer's disease and hippocampal structure in healthy people.. The American journal of psychiatry, 2010.
Donix M, Burggren AC, Suthana NA, Siddarth P, Ekstrom AD, Krupa AK, Jones M, Rao A, Martin-Harris L, Ercoli LM, Miller KJ, Small GW, Bookheimer SY. Longitudinal changes in medial temporal cortical thickness in normal subjects with the APOE-4 polymorphism.. NeuroImage, 2010.
Shineman DW, Salthouse TA, Launer LJ, Hof PR, Bartzokis G, Kleiman R, Luine V, Buccafusco JJ, Small GW, Aisen PS, Lowe DA, Fillit HM. Therapeutics for cognitive aging.. Annals of the New York Academy of Sciences, 2010.
Cole GB, Keum G, Liu J, Small GW, Satyamurthy N, Kepe V, Barrio JR. Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates.. Proceedings of the National Academy of Sciences of the United States of America, 2010.
Ercoli LM, Siddarth P, Barrio JR, Small GW. Response to Letter from Shin and Lee, entitled "FDDNP PET patterns in nondemented populations". The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010.
Wardak M, Wong KP, Shao W, Dahlbom M, Kepe V, Satyamurthy N, Small GW, Barrio JR, Huang SC. Movement correction method for human brain PET images: application to quantitative analysis of dynamic 18F-FDDNP scans.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010.
Small GW. Pharmacotherapy and other treatments for elderly patients with depression.. The Journal of clinical psychiatry, 2010.
Suthana NA, Krupa A, Donix M, Burggren A, Ekstrom AD, Jones M, Ercoli LM, Miller KJ, Siddarth P, Small GW, Bookheimer SY. Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease.. NeuroImage, 2009.
Small GW. Differential diagnoses and assessment of depression in elderly patients.. The Journal of clinical psychiatry, 2009.
Braskie MN, Small GW, Bookheimer SY. Entorhinal cortex structure and functional MRI response during an associative verbal memory task.. Human brain mapping, 2009.
Wong KP, Wardak M, Shao W, Dahlbom M, Kepe V, Liu J, Satyamurthy N, Small GW, Barrio JR, Huang SC. Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region.. European journal of nuclear medicine and molecular imaging, 2009.
Apostolova LG, Thompson PM, Rogers SA, Dinov ID, Zoumalan C, Steiner CA, Siu E, Green AE, Small GW, Toga AW, Cummings JL, Phelps ME, Silverman DH. Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly.. Molecular imaging and biology, 2009.
Barrio JR, Satyamurthy N, Huang SC, Petric A, Small GW, Kepe V. Dissecting molecular mechanisms in the living brain of dementia patients.. Accounts of chemical research, 2009.
Kepe V, Ghetti B, Farlow MR, Bresjanac M, Miller K, Huang SC, Wong KP, Murrell JR, Piccardo P, Epperson F, Repovs G, Smid LM, Petric A, Siddarth P, Liu J, Satyamurthy N, Small GW, Barrio JR. PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker disease.. Brain pathology (Zurich, Switzerland), 2009.
Lavretsky H, Siddarth P, Kepe V, Ercoli LM, Miller KJ, Burggren AC, Bookheimer SY, Huang SC, Barrio JR, Small GW. Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older nondemented adults.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009.
Ercoli LM, Siddarth P, Kepe V, Miller KJ, Huang SC, Cole GM, Lavretsky H, Bookheimer SY, Kim J, Phelps ME, Barrio JR, Small GW. Differential FDDNP PET patterns in nondemented middle-aged and older adults.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009.
Small GW, Moody TD, Siddarth P, Bookheimer SY. Your brain on Google: patterns of cerebral activation during internet searching.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009.
Small GW, Siddarth P, Burggren AC, Kepe V, Ercoli LM, Miller KJ, Lavretsky H, Thompson PM, Cole GM, Huang SC, Phelps ME, Bookheimer SY, Barrio JR. Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia.. Archives of general psychiatry, 2009.
Small GW, Siddarth P, Silverman DH, Ercoli LM, Miller KJ, Lavretsky H, Bookheimer SY, Huang SC, Barrio JR, Phelps ME. Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008.
Braskie MN, Klunder AD, Hayashi KM, Protas H, Kepe V, Miller KJ, Huang SC, Barrio JR, Ercoli LM, Siddarth P, Satyamurthy N, Liu J, Toga AW, Bookheimer SY, Small GW, Thompson PM. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease.. Neurobiology of aging, 2008.
Braskie MN, Small GW, Bookheimer SY. Vascular health risks and fMRI activation during a memory task in older adults.. Neurobiology of aging, 2008.
Rasgon NL, Kenna HA, Geist C, Small G, Silverman D. Cerebral metabolic patterns in untreated postmenopausal women with major depressive disorder.. Psychiatry research, 2008.
Silverman DH, Mosconi L, Ercoli L, Chen W, Small GW. Positron emission tomography scans obtained for the evaluation of cognitive dysfunction.. Seminars in nuclear medicine, 2008.
Kenna HA, Rasgon NL, Geist C, Small G, Silverman D. Thalamo-Basal Ganglia connectivity in postmenopausal women receiving estrogen therapy.. Neurochemical research, 2008.
Kumar A, Ajilore O, Kepe V, Barrio JR, Small G. Mood, cognition and in vivo protein imaging: the emerging nexus in clinical neuroscience.. International journal of geriatric psychiatry, 2008.
Small GW, Bookheimer SY, Thompson PM, Cole GM, Huang SC, Kepe V, Barrio JR. Current and future uses of neuroimaging for cognitively impaired patients.. The Lancet. Neurology, 2008.
Small G, Dubois B. A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch.. Current medical research and opinion, 2007.
Cummings J, Lefèvre G, Small G, Appel-Dingemanse S. Pharmacokinetic rationale for the rivastigmine patch.. Neurology, 2007.
Small GW, Kepe V, Ercoli LM, Siddarth P, Bookheimer SY, Miller KJ, Lavretsky H, Burggren AC, Cole GM, Vinters HV, Thompson PM, Huang SC, Satyamurthy N, Phelps ME, Barrio JR. PET of brain amyloid and tau in mild cognitive impairment.. The New England journal of medicine, 2006.
Small GW, Kepe V, Barrio JR. Seeing is believing: neuroimaging adds to our understanding of cerebral pathology.. Current opinion in psychiatry, 2006.
Small GW. Diagnostic issues in dementia: neuroimaging as a surrogate marker of disease.. Journal of geriatric psychiatry and neurology, 2006.
Small GW, Silverman DH, Siddarth P, Ercoli LM, Miller KJ, Lavretsky H, Wright BC, Bookheimer SY, Barrio JR, Phelps ME. Effects of a 14-day healthy longevity lifestyle program on cognition and brain function.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2006.
Ercoli L, Siddarth P, Huang SC, Miller K, Bookheimer SY, Wright BC, Phelps ME, Small G. Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease.. Archives of general psychiatry, 2006.
Kepe V, Barrio JR, Huang SC, Ercoli L, Siddarth P, Shoghi-Jadid K, Cole GM, Satyamurthy N, Cummings JL, Small GW, Phelps ME. Serotonin 1A receptors in the living brain of Alzheimer's disease patients.. Proceedings of the National Academy of Sciences of the United States of America, 2006.
Kepe V, Huang SC, Small GW, Satyamurthy N, Barrio JR. Visualizing pathology deposits in the living brain of patients with Alzheimer's disease.. Methods in enzymology, 2006.
Farlow MR, Small GW, Quarg P, Krause A. Efficacy of rivastigmine in Alzheimer's disease patients with rapid disease progression: results of a meta-analysis.. Dementia and geriatric cognitive disorders, 2005.
Shoghi-Jadid K, Barrio JR, Kepe V, Wu HM, Small GW, Phelps ME, Huang SC. Imaging beta-amyloid fibrils in Alzheimer's disease: a critical analysis through simulation of amyloid fibril polymerization.. Nuclear medicine and biology, 2005.
Small GW, Kaufer D, Mendiondo MS, Quarg P, Spiegel R. Cognitive performance in Alzheimer's disease patients receiving rivastigmine for up to 5 years.. International journal of clinical practice, 2005.
Rasgon NL, Silverman D, Siddarth P, Miller K, Ercoli LM, Elman S, Lavretsky H, Huang SC, Phelps ME, Small GW. Estrogen use and brain metabolic change in postmenopausal women.. Neurobiology of aging, 2005.
Miller KJ, Rogers SA, Siddarth P, Small GW. Object naming and semantic fluency among individuals with genetic risk for Alzheimer's disease.. International journal of geriatric psychiatry, 2005.
van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, Welsh-Bohmer KA, Saunders AM, Roses AD, Small GW, Schmechel DE, Murali Doraiswamy P, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA. Analysis of European mitochondrial haplogroups with Alzheimer disease risk.. Neuroscience letters, 2004.
Small GW. What does imaging add to the management of Alzheimer's disease?. CNS spectrums, 2004.
Cummings JL, Silverman D, Small G, Phelps M. The role of positron emission tomography in the diagnosis of Alzheimer's disease.. Journal of the American Geriatrics Society, 2004.
Grossberg GT, Corey-Bloom J, Small GW, Tariot PN. Academic highlights: emerging therapeutic strategies in Alzheimer's disease.. The Journal of clinical psychiatry, 2004.
Small GW. Neuroimaging as a diagnostic tool in dementia with Lewy bodies.. Dementia and geriatric cognitive disorders, 2004.
Agdeppa ED, Kepe V, Liu J, Small GW, Huang SC, Petric A, Satyamurthy N, Barrio JR. 2-Dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease.. Molecular imaging and biology, 2003.
Lavretsky H, Ercoli L, Siddarth P, Bookheimer S, Miller K, Small G. Apolipoprotein epsilon4 allele status, depressive symptoms, and cognitive decline in middle-aged and elderly persons without dementia.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2003.
Silverman DH, Truong CT, Kim SK, Chang CY, Chen W, Kowell AP, Cummings JL, Czernin J, Small GW, Phelps ME. Prognostic value of regional cerebral metabolism in patients undergoing dementia evaluation: comparison to a quantifying parameter of subsequent cognitive performance and to prognostic assessment without PET.. Molecular genetics and metabolism, 2003.
Li YJ, Oliveira SA, Xu P, Martin ER, Stenger JE, Scherzer CR, Hauser MA, Scott WK, Small GW, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Goetz CG, Mastaglia F, Middleton LT, Roses AD, Saunders AM, Schmechel DE, Gullans SR, Haines JL, Gilbert JR, Vance JM, Pericak-Vance MA, Hulette C, Welsh-Bohmer KA. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.. Human molecular genetics, 2003.
Scott WK, Hauser ER, Schmechel DE, Welsh-Bohmer KA, Small GW, Roses AD, Saunders AM, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.. American journal of human genetics, 2003.
Oliveira SA, Martin ER, Scott WK, Nicodemus KK, Small GW, Schmechel DE, Doraiswamy PM, Roses AD, Saunders AM, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA. The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.. Neuroscience letters, 2003.
Oliveira SA, Scott WK, Nance MA, Watts RL, Hubble JP, Koller WC, Lyons KE, Pahwa R, Stern MB, Hiner BC, Jankovic J, Ondo WG, Allen FH, Scott BL, Goetz CG, Small GW, Mastaglia FL, Stajich JM, Zhang F, Booze MW, Reaves JA, Middleton LT, Haines JL, Pericak-Vance MA, Vance JM, Martin ER. Association study of Parkin gene polymorphisms with idiopathic Parkinson disease.. Archives of neurology, 2003.
Erkinjuntti T, Kurz A, Small GW, Bullock R, Lilienfeld S, Damaraju CV, GAL-INT-6 Study Group . An open-label extension trial of galantamine in patients with probable vascular dementia and mixed dementia.. Clinical therapeutics, 2003.
Ercoli LM, Siddarth P, Dunkin JJ, Bramen J, Small GW. MMSE items predict cognitive decline in persons with genetic risk for Alzheimer's disease.. Journal of geriatric psychiatry and neurology, 2003.
Oliveira SA, Scott WK, Martin ER, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Ondo WG, Allen FH, Scott BL, Goetz CG, Small GW, Mastaglia F, Stajich JM, Zhang F, Booze MW, Winn MP, Middleton LT, Haines JL, Pericak-Vance MA, Vance JM. Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.. Annals of neurology, 2003.
van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Goetz CG, Small GW, Mastaglia F, Stajich JM, McLaurin AC, Middleton LT, Scott BL, Schmechel DE, Pericak-Vance MA, Vance JM. Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease.. American journal of human genetics, 2003.
Small G, Erkinjuntti T, Kurz A, Lilienfeld S. Galantamine in the treatment of cognitive decline in patients with vascular dementia or Alzheimer's disease with cerebrovascular disease.. CNS drugs, 2003.
Small GW. Use of neuroimaging to detect early brain changes in people at genetic risk for Alzheimer's disease.. Advanced drug delivery reviews, 2002.
Small GW, Agdeppa ED, Kepe V, Satyamurthy N, Huang SC, Barrio JR. In vivo brain imaging of tangle burden in humans.. Journal of molecular neuroscience : MN, 2002.
Miller KJ, Conney JC, Rasgon NL, Fairbanks LA, Small GW. Mood symptoms and cognitive performance in women estrogen users and nonusers and men.. Journal of the American Geriatrics Society, 2002.
Silverman DH, Small GW. Prompt identification of Alzheimer's disease with brain PET imaging of a woman with multiple previous diagnoses of other neuropsychiatric conditions.. The American journal of psychiatry, 2002.
Small GW. Brain-imaging surrogate markers for detection and prevention of age-related memory loss.. Journal of molecular neuroscience : MN, 2002.
Silverman DH, Cummings JL, Small GW, Gambhir SS, Chen W, Czernin J, Phelps ME. Added clinical benefit of incorporating 2-deoxy-2-[18F]fluoro-D-glucose with positron emission tomography into the clinical evaluation of patients with cognitive impairment.. Molecular imaging and biology, 2002.
Small GW. What we need to know about age related memory loss.. BMJ (Clinical research ed.), 2002.
Mega MS, Small GW, Xu ML, Felix J, Manese M, Tran NP, Dailey JI, Ercoli LM, Bookheimer SY, Toga AW. Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space.. Psychosomatic medicine, 2002.
Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. Age at onset in two common neurodegenerative diseases is genetically controlled.. American journal of human genetics, 2002.
Silverman DH, Gambhir SS, Huang HW, Schwimmer J, Kim S, Small GW, Chodosh J, Czernin J, Phelps ME. Evaluating early dementia with and without assessment of regional cerebral metabolism by PET: a comparison of predicted costs and benefits.. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002.
Small GW, McDonnell DD, Brooks RL, Papadopoulos G. The impact of symptom severity on the cost of Alzheimer's disease.. Journal of the American Geriatrics Society, 2002.
Jann MW, Shirley KL, Small GW. Clinical pharmacokinetics and pharmacodynamics of cholinesterase inhibitors.. Clinical pharmacokinetics, 2002.
Shoghi-Jadid K, Small GW, Agdeppa ED, Kepe V, Ercoli LM, Siddarth P, Read S, Satyamurthy N, Petric A, Huang SC, Barrio JR. Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2002.
Burggren AC, Small GW, Sabb FW, Bookheimer SY. Specificity of brain activation patterns in people at genetic risk for Alzheimer disease.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2002.
Small GW. The role of neuroimaging in the diagnosis of vascular dementia.. Acta neurologica Scandinavica. Supplementum, 2002.
Small GW. Vascular dementia: galantamine (Reminyl) as an emerging therapeutic option.. Acta neurologica Scandinavica. Supplementum, 2002.
Small GW, Chen ST, Komo S, Ercoli L, Miller K, Siddarth P, Kaplan A, Dorsey D, Lavretsky H, Saxena S, Bookheimer SY. Memory self-appraisal and depressive symptoms in people at genetic risk for Alzheimer's disease.. International journal of geriatric psychiatry, 2001.
Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, Wu HM, Mega MS, Cummings JL, Saunders AM, Pericak-Vance MA, Roses AD, Barrio JR, Phelps ME. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.. Proceedings of the National Academy of Sciences of the United States of America, 2000.
Small GW. Investigations into geriatric psychiatry challenges: AAGP Senior Investigator Award 2000.. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2000.
Small GW, Chen ST, Komo S, Ercoli L, Bookheimer S, Miller K, Lavretsky H, Saxena S, Kaplan A, Dorsey D, Scott WK, Saunders AM, Haines JL, Roses AD, Pericak-Vance MA. Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.. The American journal of psychiatry, 1999.
Silverman DH, Small GW, Phelps ME. Clinical Value of Neuroimaging in the Diagnosis of Dementia. Sensitivity and Specificity of Regional Cerebral Metabolic and Other Parameters for Early Identification of Alzheimer's Disease.. Clinical positron imaging : official journal of the Institute for Clinical P.E.T, 1999.