Ira Kurtz, M.D.

Chief, Nephrology Professor, Medicine Member, Brain Research Institute

ikurtz@mednet.ucla.edu

(310) 206-7662

UCLA Med-Neph
BOX 951689, 7-155 Factor
Los Angeles, CA 90095
UNITED STATES

Website

Publications

Zamanzadeh D, Feng J, Petousis P, Vepa A, Sarrafzadeh M, Karumanchi SA, Bui AAT, Kurtz I. Data-driven prediction of continuous renal replacement therapy survival.. Nature communications, 2024.
Zhekova HR, Ramirez Echemendía DP, Sejdiu BI, Pushkin A, Tieleman DP, Kurtz I. Molecular dynamics simulations of lipid-protein interactions in SLC4 proteins.. Biophysical journal, 2024.
Zamanzadeh D, Feng J, Petousis P, Vepa A, Sarrafzadeh M, Karumanchi SA, Bui AAT, Kurtz I. Data-driven prediction of continuous renal replacement therapy survival.. Research square, 2023.
Zhekova HR, Ramirez-Echemendía DP, Sejdiu BI, Pushkin A, Tieleman DP, Kurtz I. Coarse-grained molecular dynamics simulations of lipid-protein interactions in SLC4 proteins.. bioRxiv : the preprint server for biology, 2023.
Kraut JA, Cheetham-Wilkinson IJ, Swan LE, Stagi M, Kurtz I. Impact of various buffers and weak bases on lysosomal and intracellular pH: Implications for infectivity of SARS-CoV-2.. FASEB bioAdvances, 2023.
Kurtz I, Schwartz GJ. Base (HCO3-/CO32-) Transport Properties of SLC4 Proteins: New Insights in Acid-Base Kidney Physiology.. Journal of the American Society of Nephrology : JASN, 2023.
Zhekova HR, Jiang J, Wang W, Tsirulnikov K, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Tieleman DP, Hong Zhou Z, Pushkin A, Kurtz I. CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.. Communications biology, 2022.
Hanna RM, Ahdoot RS, Kalantar-Zadeh K, Ghobry L, Kurtz I. Calcium Transport in the Kidney and Disease Processes.. Frontiers in endocrinology, 2022.
Hanna RM, Ahdoot RS, Kim MS, Jhaveri KD, Kalantar-Zadeh K, Kurtz IB. Intravitreal vascular endothelial growth factors hypertension, proteinuria, and renal injury: a concise review.. Current opinion in nephrology and hypertension, 2022.
Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. Publisher Correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.. Nature communications, 2021.
Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.. Nature communications, 2021.
Zhekova HR, Pushkin A, Kayik G, Kao L, Azimov R, Abuladze N, Kurtz D, Damergi M, Noskov SY, Kurtz I. Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: Insights into the transport mechanism.. The Journal of biological chemistry, 2021.
Phadke G, Hanna RM, Ferrey A, Torres EA, Singla A, Kaushal A, Kalantar-Zadeh K, Kurtz I, Jhaveri KD. Review of intravitreal VEGF inhibitor toxicity and report of collapsing FSGS with TMA in a patient with age-related macular degeneration.. Clinical kidney journal, 2021.
Ahn IS, Lang JM, Olson CA, Diamante G, Zhang G, Ying Z, Byun HR, Cely I, Ding J, Cohn P, Kurtz I, Gomez-Pinilla F, Lusis AJ, Hsiao EY, Yang X. Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to Fructose Consumption in Mice.. The Journal of nutrition, 2020.
Hanna RM, Tran NT, Patel SS, Hou J, Jhaveri KD, Parikh R, Selamet U, Ghobry L, Wassef O, Barsoum M, Bijol V, Kalantar-Zadeh K, Pai A, Amin A, Kupperman B, Kurtz IB. Thrombotic Microangiopathy and Acute Kidney Injury Induced After Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors VEGF Blockade-Related TMA After Intravitreal Use.. Frontiers in medicine, 2020.
Hanna RM, Abdelnour L, Zuckerman JE, Ferrey AJ, Pai A, Vahabzadeh K, Wilson J, Torres EA, Kalantar-Zadeh K, Kurtz IB. Refractory scleroderma renal crisis precipitated after high-dose oral corticosteroids and concurrent intravitreal injection of bevacizumab.. SAGE open medical case reports, 2020.
Zhang W, Frausto R, Chung DD, Griffis CG, Kao L, Chen A, Azimov R, Sampath AP, Kurtz I, Aldave AJ. Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies.. Investigative ophthalmology & visual science, 2020.
Hanna RM, Hou J, Hasnain H, Arman F, Selamet U, Wilson J, Olanrewaju S, Zuckerman JE, Barsoum M, Yabu JM, Kurtz I. Diverse Clinical Presentations of C3 Dominant Glomerulonephritis.. Frontiers in medicine, 2020.
Shye M, Hanna RM, Patel SS, Tram-Tran N, Hou J, Mccannel C, Khalid M, Hanna M, Abdelnour L, Kurtz I. Worsening proteinuria and renal function after intravitreal vascular endothelial growth factor blockade for diabetic proliferative retinopathy.. Clinical kidney journal, 2020.
He C, Song W, Weston TA, Tran C, Kurtz I, Zuckerman JE, Guagliardo P, Miner JH, Ivanov SV, Bougoure J, Hudson BG, Colon S, Voziyan PA, Bhave G, Fong LG, Young SG, Jiang H. Peroxidasin-mediated bromine enrichment of basement membranes.. Proceedings of the National Academy of Sciences of the United States of America, 2020.
Frausto RF, Swamy VS, Peh GSL, Boere PM, Hanser EM, Chung DD, George BL, Morselli M, Kao L, Azimov R, Wu J, Pellegrini M, Kurtz I, Mehta JS, Aldave AJ. Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion.. Scientific reports, 2020.
Selamet U, Hanna RM, Sisk A, Abdelnour L, Ghobry L, Kurtz I. Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report.. SAGE open medical case reports, 2020.
Hanna RM, Abdelnour L, Hasnain H, Selamet U, Kurtz I. Intravitreal bevacizumab-induced exacerbation of proteinuria in diabetic nephropathy, and amelioration by switching to ranibizumab.. SAGE open medical case reports, 2020.
Nguyen MK, Song L, Kao L, Tong K, De La Cruz MJ, Rodriguez G, Nguyen MK, Nguyen DS, Kurtz I. Is the Osmolal Concentration of Ethanol Greater Than Its Molar Concentration?. Frontiers in medicine, 2020.
Yang NY, Mukaibo T, Gao X, Kurtz I, Melvin JE. Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands.. Physiological reports, 2019.
Kao L, Azimov R, Shao XM, Abuladze N, Newman D, Zhekova H, Noskov S, Pushkin A, Kurtz I. SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport.. American journal of physiology. Cell physiology, 2019.
Hanna RM, Velez JC, Rastogi A, Nguyen MK, Kamgar MK, Moe K, Arman F, Hasnain H, Nobakht N, Selamet U, Kurtz I. Equivalent Efficacy and Decreased Rate of Overcorrection in Patients With Syndrome of Inappropriate Secretion of Antidiuretic Hormone Given Very Low-Dose Tolvaptan.. Kidney medicine, 2019.
Hanna RM, Merin N, Burwick RM, Abdelnour L, Selamet U, Yanny B, Bui P, Fouad M, Kurtz I. Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease.. Thrombosis journal, 2019.
Frausto RF, Chung DD, Boere PM, Swamy VS, Duong HNV, Kao L, Azimov R, Zhang W, Carrigan L, Wong D, Morselli M, Zakharevich M, Hanser EM, Kassels AC, Kurtz I, Pellegrini M, Aldave AJ. ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing.. PloS one, 2019.
Hanna RM, Barsoum M, Vandross A, Kurtz I, Burwick R. Atypical hemolytic uremic syndrome and complement blockade: established and emerging uses of complement inhibition.. Current opinion in nephrology and hypertension, 2019.
Gee MT, Kurtz I, Pannabecker TL. Expression of SLC4A11 protein in mouse and rat medulla: a candidate transporter involved in outer medullary ammonia recycling.. Physiological reports, 2019.
Hanna RM, Barsoum M, Arman F, Selamet U, Hasnain H, Kurtz I. Nephrotoxicity induced by intravitreal vascular endothelial growth factor inhibitors: emerging evidence.. Kidney international, 2019.
Yang NY, Mukaibo T, Kurtz I, Melvin JE. The apical Na+ -HCO3- cotransporter Slc4a7 (NBCn1) does not contribute to bicarbonate transport by mouse salivary gland ducts.. Journal of cellular physiology, 2019.
Lang JM, Pan C, Cantor RM, Tang WHW, Garcia-Garcia JC, Kurtz I, Hazen SL, Bergeron N, Krauss RM, Lusis AJ. Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome.. mBio, 2018.
Song L, Hanna RM, Nguyen MK, Kurtz I, Wilson J. A Novel Case of Pseudohyponatremia Caused by Hypercholesterolemia.. Kidney international reports, 2018.
Kurtz I. Renal Tubular Acidosis: H+/Base and Ammonia Transport Abnormalities and Clinical Syndromes.. Advances in chronic kidney disease, 2018.
Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.. Nature communications, 2018.
Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I. Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.. Journal of Cancer, 2018.
Kao L, Azimov R, Shao XM, Frausto RF, Abuladze N, Newman D, Aldave AJ, Kurtz I. Multifunctional ion transport properties of human SLC4A11: comparison of the SLC4A11-B and SLC4A11-C variants.. American journal of physiology. Cell physiology, 2016.
Yin K, Lei Y, Wen X, Lacruz RS, Soleimani M, Kurtz I, Snead ML, White SN, Paine ML. SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.. PloS one, 2015.
Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography.. The Journal of biological chemistry, 2015.
Shcheynikov N, Son A, Hong JH, Yamazaki O, Ohana E, Kurtz I, Shin DM, Muallem S. Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters.. Proceedings of the National Academy of Sciences of the United States of America, 2015.
Shao XM, Kao L, Kurtz I. A novel delta current method for transport stoichiometry estimation.. BMC biophysics, 2014.
Kraut JA, Kurtz I. Treatment of acute non-anion gap metabolic acidosis.. Clinical kidney journal, 2014.
Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. Human SLC4A11-C functions as a DIDS-stimulatable H⁺(OH⁻) permeation pathway: partial correction of R109H mutant transport.. American journal of physiology. Cell physiology, 2014.
Kurtz I. Molecular mechanisms and regulation of urinary acidification.. Comprehensive Physiology, 2014.
Nguyen MK, Ornekian V, Kao L, Butch AW, Kurtz I. Defining the role of albumin infusion in cirrhosis-associated hyponatremia.. American journal of physiology. Gastrointestinal and liver physiology, 2014.
Wen X, Kurtz I, Paine ML. Prevention of the disrupted enamel phenotype in Slc4a4-null mice using explant organ culture maintained in a living host kidney capsule.. PloS one, 2014.
Kurtz I. NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease.. Pflugers Archiv : European journal of physiology, 2014.
Kurtz I, Zhu Q. Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties.. Frontiers in physiology, 2013.
Kurtz I, Zhu Q. Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis.. Current opinion in nephrology and hypertension, 2013.
Zhu Q, Shao XM, Kao L, Azimov R, Weinstein AM, Newman D, Liu W, Kurtz I. Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis.. American journal of physiology. Cell physiology, 2013.
Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A, Zhou ZH, Kurtz I. Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains.. PloS one, 2013.
Zhu Q, Liu W, Kao L, Azimov R, Newman D, Abuladze N, Kurtz I. Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation.. The Journal of biological chemistry, 2013.
Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein.. FEBS letters, 2012.
Hu P, Lacruz RS, Smith CE, Smith SM, Kurtz I, Paine ML. Expression of the sodium/calcium/potassium exchanger, NCKX4, in ameloblasts.. Cells, tissues, organs, 2012.
Kurtz L, Kao L, Newman D, Kurtz I, Zhu Q. Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism.. The Journal of biological chemistry, 2012.
Kao L, Abuladze N, Shao XM, McKeegan K, Kurtz I. A new technique for multiple re-use of planar patch clamp chips.. Journal of neuroscience methods, 2012.
Lacruz RS, Smith CE, Bringas P, Chen YB, Smith SM, Snead ML, Kurtz I, Hacia JG, Hubbard MJ, Paine ML. Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling.. Journal of cellular physiology, 2012.
Burette AC, Weinberg RJ, Sassani P, Abuladze N, Kao L, Kurtz I. The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.. The Journal of comparative neurology, 2012.
Sergeev M, Godin AG, Kao L, Abuladze N, Wiseman PW, Kurtz I. Determination of membrane protein transporter oligomerization in native tissue using spatial fluorescence intensity fluctuation analysis.. PloS one, 2012.
Lacruz RS, Smith CE, Moffatt P, Chang EH, Bromage TG, Bringas P, Nanci A, Baniwal SK, Zabner J, Welsh MJ, Kurtz I, Paine ML. Requirements for ion and solute transport, and pH regulation during enamel maturation.. Journal of cellular physiology, 2012.
Snead CM, Smith SM, Sadeghein N, Lacruz RS, Hu P, Kurtz I, Paine ML. Identification of a pH-responsive DNA region upstream of the transcription start site of human NBCe1-B.. European journal of oral sciences, 2011.
Nguyen MK, Kao L, Kurtz I. Defining the buffering process by a triprotic acid without relying on Stewart-electroneutrality considerations.. Theoretical biology & medical modelling, 2011.
Kao L, Kurtz LM, Shao X, Papadopoulos MC, Liu L, Bok D, Nusinowitz S, Chen B, Stella SL, Andre M, Weinreb J, Luong SS, Piri N, Kwong JM, Newman D, Kurtz I. Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).. The Journal of biological chemistry, 2011.
Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. Structures of aminoacylase 3 in complex with acetylated substrates.. Proceedings of the National Academy of Sciences of the United States of America, 2010.
Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I. Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A.. The Journal of biological chemistry, 2010.
Lacruz RS, Nanci A, White SN, Wen X, Wang H, Zalzal SF, Luong VQ, Schuetter VL, Conti PS, Kurtz I, Paine ML. The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition.. The Journal of biological chemistry, 2010.
Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I. Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis.. The Journal of biological chemistry, 2010.
Lacruz RS, Hilvo M, Kurtz I, Paine ML. A survey of carbonic anhydrase mRNA expression in enamel cells.. Biochemical and biophysical research communications, 2010.
Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).. Toxicology and applied pharmacology, 2010.
Lacruz RS, Nanci A, Kurtz I, Wright JT, Paine ML. Regulation of pH During Amelogenesis.. Calcified tissue international, 2009.
Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I. Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities.. The Journal of biological chemistry, 2009.
Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel.. Biochimica et biophysica acta, 2009.
Nguyen MK, Kao L, Kurtz I. Calculation of the equilibrium pH in a multiple-buffered aqueous solution based on partitioning of proton buffering: a new predictive formula.. American journal of physiology. Renal physiology, 2009.
Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I. NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway.. The Journal of biological chemistry, 2009.
Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I. Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A.. The Journal of biological chemistry, 2008.
Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis.. American journal of physiology. Renal physiology, 2008.
Nguyen MK, Kurtz I. Correction of hypervolaemic hypernatraemia by inducing negative Na+ and K+ balance in excess of negative water balance: a new quantitative approach.. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008.
Pushkin A, Kurtz I. Measurement of aminoacylases.. Current protocols in toxicology, 2008.
Kurtz I, Kraut J, Ornekian V, Nguyen MK. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches.. American journal of physiology. Renal physiology, 2008.
Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management.. Clinical journal of the American Society of Nephrology : CJASN, 2007.
Aldave AJ, Yellore VS, Bourla N, Momi RS, Khan MA, Salem AK, Rayner SA, Glasgow BJ, Kurtz I. Autosomal recessive CHED associated with novel compound heterozygous mutations in SLC4A11.. Cornea, 2007.
Ryazantsev S, Abuladze N, Newman D, Bondar G, Kurtz I, Pushkin A. Structural characterization of dimeric murine aminoacylase III.. FEBS letters, 2007.
Nguyen MK, Ornekian V, Butch AW, Kurtz I. A new method for determining plasma water content: application in pseudohyponatremia.. American journal of physiology. Renal physiology, 2007.
Suh WM, Wainberg ZA, de Vos S, Cohen AH, Kurtz I, Nguyen MK. Acute lymphoblastic leukemia presenting as acute renal failure.. Nature clinical practice. Nephrology, 2007.
Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.. Drug metabolism and disposition: the biological fate of chemicals, 2006.
Nguyen MK, Kurtz I. Is the osmotically inactive sodium storage pool fixed or variable?. Journal of applied physiology (Bethesda, Md. : 1985), 2006.
Nguyen MK, Rastogi A, Kurtz I. True hyponatremia secondary to intravenous immunoglobulin.. Clinical and experimental nephrology, 2006.
Kraut JA, Kurtz I. Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey.. Clinical and experimental nephrology, 2006.
Kalantar-Zadeh K, Nguyen MK, Chang R, Kurtz I. Fatal hyponatremia in a young woman after ecstasy ingestion.. Nature clinical practice. Nephrology, 2006.
Pushkin A, Kurtz I. SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models.. American journal of physiology. Renal physiology, 2006.
Nguyen MK, Kurtz I. Whole-body electrolyte-free water clearance: derivation and clinical utility in analyzing the pathogenesis of the dysnatremias.. Clinical and experimental nephrology, 2006.
Galbraith G, Waschek J, Armstrong B, Edmond J, Lopez I, Liu W, Kurtz I. Murine auditory brainstem evoked response: putative two-channel differentiation of peripheral and central neural pathways.. Journal of neuroscience methods, 2006.
Nguyen MK, Kurtz I. Quantitative interrelationship between Gibbs-Donnan equilibrium, osmolality of body fluid compartments, and plasma water sodium concentration.. Journal of applied physiology (Bethesda, Md. : 1985), 2005.
Kurtz I, Nguyen MK. Evolving concepts in the quantitative analysis of the determinants of the plasma water sodium concentration and the pathophysiology and treatment of the dysnatremias.. Kidney international, 2005.
Lopez IA, Acuna D, Galbraith G, Bok D, Ishiyama A, Liu W, Kurtz I. Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7).. Brain research. Developmental brain research, 2005.
Kim YH, Verlander JW, Matthews SW, Kurtz I, Shin W, Weiner ID, Everett LA, Green ED, Nielsen S, Wall SM. Intercalated cell H+/OH- transporter expression is reduced in Slc26a4 null mice.. American journal of physiology. Renal physiology, 2005.
Kraut JA, Kurtz I. Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment.. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005.
Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I. Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport.. The Journal of physiology, 2005.
Nguyen MK, Kurtz I. An analysis of current quantitative approaches to the treatment of severe symptomatic SIADH with intravenous saline therapy.. Clinical and experimental nephrology, 2005.
Nguyen MK, Kurtz I. A new formula for predicting alterations in plasma sodium concentration in peritoneal dialysis.. American journal of physiology. Renal physiology, 2004.
Nguyen MK, Kurtz I. Derivation of a new formula for calculating urinary electrolyte-free water clearance based on the Edelman equation.. American journal of physiology. Renal physiology, 2004.
Nguyen MK, Kurtz I. New insights into the pathophysiology of the dysnatremias: a quantitative analysis.. American journal of physiology. Renal physiology, 2004.
Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I. Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells.. The Journal of physiology, 2004.
Nguyen MK, Kurtz I. Role of potassium in hypokalemia-induced hyponatremia: lessons learned from the Edelman equation.. Clinical and experimental nephrology, 2004.
Abuladze N, Pushkin A, Tatishchev S, Newman D, Sassani P, Kurtz I. Expression and localization of rat NBC4c in liver and renal uroepithelium.. American journal of physiology. Cell physiology, 2004.
Nguyen MK, Kurtz I. Analysis of current formulas used for treatment of the dysnatremias.. Clinical and experimental nephrology, 2004.
Nguyen MK, Kurtz I. Determinants of plasma water sodium concentration as reflected in the Edelman equation: role of osmotic and Gibbs-Donnan equilibrium.. American journal of physiology. Renal physiology, 2004.
Kurtz I, Petrasek D, Tatishchev S. Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations.. The Journal of membrane biology, 2004.
Pushkin A, Carpenito G, Abuladze N, Newman D, Tsuprun V, Ryazantsev S, Motemoturu S, Sassani P, Solovieva N, Dukkipati R, Kurtz I. Structural characterization, tissue distribution, and functional expression of murine aminoacylase III.. American journal of physiology. Cell physiology, 2003.
Woo DD, Kurtz I. Mapping blood pressure loci in (A/J x B6)F2 mice.. Physiological genomics, 2003.
Nguyen MK, Kurtz I. An unusual case of pseudohyperkalaemia.. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003.
Nguyen MK, Kurtz I. Are the total exchangeable sodium, total exchangeable potassium and total body water the only determinants of the plasma water sodium concentration?. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003.
Bok D, Galbraith G, Lopez I, Woodruff M, Nusinowitz S, BeltrandelRio H, Huang W, Zhao S, Geske R, Montgomery C, Van Sligtenhorst I, Friddle C, Platt K, Sparks MJ, Pushkin A, Abuladze N, Ishiyama A, Dukkipati R, Liu W, Kurtz I. Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3.. Nature genetics, 2003.
Nguyen MK, Kurtz I. A new quantitative approach to the treatment of the dysnatremias.. Clinical and experimental nephrology, 2003.
Kurtz I, Nguyen MK. A simple quantitative approach to analyzing the generation of the dysnatremias.. Clinical and experimental nephrology, 2003.
Nguyen MK, Nielsen S, Kurtz I. Molecular pathogenesis of nephrogenic diabetes insipidus.. Clinical and experimental nephrology, 2003.
Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation.. Biochemistry, 2003.
Pushkin A, Abuladze N, Newman D, Muronets V, Sassani P, Tatishchev S, Kurtz I. The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.. American journal of physiology. Cell physiology, 2002.
Yip KP, Tsuruoka S, Schwartz GJ, Kurtz I. Apical H(+)/base transporters mediating bicarbonate absorption and pH(i) regulation in the OMCD.. American journal of physiology. Renal physiology, 2002.
Gross E, Pushkin A, Abuladze N, Fedotoff O, Kurtz I. Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding.. The Journal of physiology, 2002.
Gross E, Kurtz I. Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry.. American journal of physiology. Renal physiology, 2002.
Park M, Ko SB, Choi JY, Muallem G, Thomas PJ, Pushkin A, Lee MS, Kim JY, Lee MG, Muallem S, Kurtz I. The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.. The Journal of biological chemistry, 2002.
Carpenito G, Kurtz I. Green urine in a critically ill patient.. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002.
Kwon TH, Fulton C, Wang W, Kurtz I, Frøkiaer J, Aalkjaer C, Nielsen S. Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1.. American journal of physiology. Renal physiology, 2002.
Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G, Kurtz I. Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter.. American journal of physiology. Cell physiology, 2002.