Loes Olde Loohuis, Ph.D.
Assistant Professor, Psychiatry & Biobehavioral Sciences
loldeloohuis@mednet.ucla.edu
3107942723
Research Interests
Dr. Loes Olde Loohuis’ research focuses on elucidating the underlying molecular mechanisms of severe mental illness, in particular schizophrenia and bipolar disorder, by utilizing and developing computational approaches to leverage multi-level data (including psychiatric phenotypes, health records and molecular phenotypes).
Publications
- Song J, Ramírez MC, Okano JT, Service SK, de la Hoz J, Díaz-Zuluaga AM, Upegui CV, Gallago C, Arias A, Sánchez AV, Teshiba T, Sabatti C, Gur RC, Bearden CE, Escobar JI, Reus VI, Jaramillo CL, Freimer NB, Olde Loohuis LM, Blower S. Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders.. Communications medicine, 2024.
- Fu M, Yan Y, Olde Loohuis LM, Chang TS. Defining the distance between diseases using SNOMED CT embeddings.. Journal of biomedical informatics, 2023.
- Olde Loohuis LM, Mennigen E, Ori APS, Perkins D, Robinson E, Addington J, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Keshavan MS, Stone WS, Tsuang MT, Walker EF, Woods SW, Cannon TD, Gur RC, Gur RE, Bearden CE, Ophoff RA. Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD.. Translational psychiatry, 2021.
- Loohuis LM, Albersen M, de Jong S, Wu T, Luykx JJ, Jans JJM, Verhoeven-Duif NM, Ophoff RA. The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma.. Genes, 2018.
- Somers M, Olde Loohuis LM, Aukes MF, Pasaniuc B, de Visser KCL, Kahn RS, Sommer IE, Ophoff RA. A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity.. Genes, 2017.