Carrie Bearden, Ph.D.

Biography

Dr. Carrie Bearden received her Ph.D. in Clinical Psychology from the University of Pennsylvania and joined the UCLA faculty as Assistant Professor in the Department of Psychiatry & Biobehavioral Sciences at UCLA in 2003. She hold a secondary appointment in the Department of Psychology. She has received numerous awards and honors, including Young Investigator Awards from the International Congress for Schizophrenia Research and the National Alliance for Research on Schizophrenia and Affective Disorders (NARSAD), and the American College of Neuropsychopharmacology (ACNP), the A.E. Bennett Neuropsychiatric Research Award for Clinical Science in Biological Psychiatry, and the Samuel Gershon Junior Investigator Award from the International Society for Bipolar Disorders. Dr. Bearden’s research aims to understand genetic influences on brain structure in the development of psychosis, using converging methods to study cognition and neuroanatomy in clinical high-risk samples (e.g., adolescents at clinical high-risk for psychosis), and in possible ‘genetic subtypes of the disease with very high penetrance (e.g, 22q11.2 microdeletions). Another active research project, conducted in collaboration with Dr. Nelson Freimer, is an NIMH-funded study of neural endophenotypes of bipolar disorder in a genetically isolated population in Latin America.

Michele Basso, Ph.D.

Biography

Dr. Michele A. Basso is a Professor in the Departments of Psychiatry and Biobehavioral Sciences and Neurobiology. She studied Neuroscience at Stony Brook University in NY and was a post-doctoral fellow at the National Eye Institute, NIH. After serving as a faculty member at the University of Wisconsin Madison, she moved to UCLA to join the faculty and direct the Fuster Laboratory of Cognitive Neuroscience. The work performed in her laboratory is aimed at unravelling the neuronal circuits of decision-making in health and disease. Her work spans multiple species and employs multiple technologies designed to understand how memory and sensory information are combined to give rise to our decisions.

Publications

A selected list of publications:

Perugini Alessandra, Basso Michele A   Perceptual decisions based on previously learned information are independent of dopaminergic tone Journal of neurophysiology, 2018; 119(3): 849-861.
Odegaard Brian, Grimaldi Piercesare, Cho Seong Hah, Peters Megan A K, Lau Hakwan, Basso Michele A   Superior colliculus neuronal ensemble activity signals optimal rather than subjective confidence Proceedings of the National Academy of Sciences of the United States of America, 2018; 115(7): E1588-E1597.
Crapse Trinity B, Lau Hakwan, Basso Michele A   A Role for the Superior Colliculus in Decision Criteria Neuron, 2018; 97(1): 181-194.e6.
May Paul J, Basso Michele A   Connections between the zona incerta and superior colliculus in the monkey and squirrel Brain structure & function, 2018; 223(1): 371-390.
Basso Michele A, May Paul J   Circuits for Action and Cognition: A View from the Superior Colliculus Annual review of vision science, 2017; 3(1): 197-226.
Ghitani Nima, Bayguinov Peter O, Basso Michele A, Jackson Meyer B   A sodium afterdepolarization in rat superior colliculus neurons and its contribution to population activity Journal of neurophysiology, 2016; 116(1): 191-200.
Perugini Alessandra, Ditterich Jochen, Basso Michele A   Patients with Parkinson’s Disease Show Impaired Use of Priors in Conditions of Sensory Uncertainty Current biology : CB, 2016; 26(14): 1902-10.
Basso Michele A   Monkey neurophysiology to clinical neuroscience and back again Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(24): 6591-3.
Crapse Trinity B, Basso Michele A   Insights into decision making using choice probability Journal of neurophysiology, 2015; 114(6): 3039-49.
Grimaldi Piercesare, Lau Hakwan, Basso Michele A   There are things that we know that we know, and there are things that we do not know we do not know: Confidence in decision-making Neuroscience and biobehavioral reviews, 2015; 55: 88-97.
Bayguinov Peter O, Ghitani Nima, Jackson Meyer B, Basso Michele A   A hard-wired priority map in the superior colliculus shaped by asymmetric inhibitory circuitry Journal of neurophysiology, 2015; 114(1): 662-76.
Vokoun Corinne R, Huang Xin, Jackson Meyer B, Basso Michele A   Response normalization in the superficial layers of the superior colliculus as a possible mechanism for saccadic averaging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(23): 7976-87.
Ghitani Nima, Bayguinov Peter O, Vokoun Corinne R, McMahon Shane, Jackson Meyer B, Basso Michele A   Excitatory synaptic feedback from the motor layer to the sensory layers of the superior colliculus The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(20): 6822-33.
Mahamed Safraaz, Garrison Tiffany J, Shires Joel, Basso Michele A   Stimulation of the Substantia Nigra Influences the Specification of Memory-Guided Saccades Journal of neurophysiology, 2013; 39(1): .
Powers Alice S, Basso Michele A, Evinger Craig   Blinks slow memory-guided saccades Journal of neurophysiology, 2013; 109(3): 734-41.
Vokoun Corinne R, Jackson Meyer B, Basso Michele A   Circuit dynamics of the superior colliculus revealed by in vitro voltage imaging Annals of the New York Academy of Sciences, 2011; 1233(2): 41-7.
Li Xiaobing, Basso Michele A   Cues to move increased information in superior colliculus tuning curves Journal of neurophysiology, 2011; 106(2): 690-703.
Shires Joel, Joshi Siddhartha, Basso Michele A   Shedding new light on the role of the basal ganglia-superior colliculus pathway in eye movements Current opinion in neurobiology, 2010; 20(6): 717-25.
Vokoun Corinne R, Jackson Meyer B, Basso Michele A   Intralaminar and interlaminar activity within the rodent superior colliculus visualized with voltage imaging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(32): 10667-82.
Kim Byounghoon, Basso Michele A   A probabilistic strategy for understanding action selection The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(6): 2340-55.
Gooding Diane C, Basso Michele A   The tell-tale tasks: a review of saccadic research in psychiatric patient populations Brain and cognition, 2008; 68(3): 371-90.
Liu Ping, Basso Michele A   Substantia nigra stimulation influences monkey superior colliculus neuronal activity bilaterally Journal of neurophysiology, 2008; 100(2): 1098-112.
Basso Michele A   Electrical stimulation of nervous system tissue. Introduction Neuroscience and biobehavioral reviews, 2008; 32(3): 331.
Li Xiaobing, Basso Michele A   Preparing to move increases the sensitivity of superior colliculus neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008; 28(17): 4561-77.
Kim Byounghoon, Basso Michele A   Saccade target selection in the superior colliculus: a signal detection theory approach The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008; 28(12): 2991-3007.
Utter Amy A, Basso Michele A   The basal ganglia: an overview of circuits and function Neuroscience and biobehavioral reviews, 2008; 32(3): 333-42.
Basso Michele A, Liu Ping   Context-dependent effects of substantia nigra stimulation on eye movements Journal of neurophysiology, 2007; 97(6): 4129-42.
Smith Joshua J, Hadzic Vezira, Li Xiaobing, Liu Ping, Day Tiffany, Utter Amy, Kim Byounghoon, Washington Ida M, Basso Michele A   Objective measures of health and well-being in laboratory rhesus monkeys (Macaca mulatta) Journal of medical primatology, 2006; 35(6): 388-96.
Li Xiaobing, Kim Byounghoon, Basso Michele A   Transient pauses in delay-period activity of superior colliculus neurons Journal of neurophysiology, 2006; 95(4): 2252-64.
Li Xiaobing, Basso Michele A   Competitive stimulus interactions within single response fields of superior colliculus neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005; 25(49): 11357-73.
Basso Michele A, Pokorny Jennifer J, Liu Ping   Activity of substantia nigra pars reticulata neurons during smooth pursuit eye movements in monkeys The European journal of neuroscience, 2005; 22(2): 448-64.
Basso Michele A, Uhlrich Daniel, Bickford Martha E   Cortical function: a view from the thalamus Neuron, 2005; 45(4): 485-8.
Williamson Shawn S, Zivotofsky Ari Z, Basso Michele A   Modulation of gaze-evoked blinks depends primarily on extraretinal factors Journal of neurophysiology, 2005; 93(1): 627-32.
Basso Michele A, Wurtz Robert H   Neuronal activity in substantia nigra pars reticulata during target selection The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002; 22(5): 1883-94.

Robert Bilder, Ph.D.

Biography

Dr. Bilder received a bachelors degree from Columbia College of Columbia University in Biology and Psychology (1978), and a Ph.D. in Psychology from City College, City University of New York, where he specialized in human neuropsychology (1984). He did his Internship in the Division of Neuropsychology, New York State Neurological Institute, Columbia-Presbyterian Medical Center (1982). Before joining UCLA in 2002, Dr. Bilder held a series of faculty appointments at Columbia University College of Physicians & Surgeons and the Albert Einstein College of Medicine. He served as Chief of Neuropsychology at Zucker Hillside Hospital of North Shore Long Island Jewish Medical Center from 1988 to 2002, and was Associate Director for Human Research at the Center for Advanced Brain Imaging at the Nathan Kline Institute for Psychiatric Research from 1996 to 2002. Dr. Bilder has been awarded diplomate status by the American Board of Clinical Neuropsychology. Dr. Bilder is a Clinical Neuropsychologist who has been actively engaged for over 30 years in research on the neuroanatomic and neuropsychological bases of major mental illnesses, and recently has been investigating the neuroscientific bases of well-being, resilience, and creative achievement. He has received many awards for his research contributions, served on diverse federal and international advisory boards, provided editorial service to many scholarly journals, and received multiple grants from the NIH, private foundations, and industry. His work has been presented in more than 200 publications and 500 scientific presentations.

Publications

A selected list of publications:

Thames April D, Hinkin Charles H, Byrd Desiree A, Bilder Robert M, Duff Kimberley J, Mindt Monica Rivera, Arentoft Alyssa, Streiff Vanessa   Effects of stereotype threat, perceived discrimination, and examiner race on neuropsychological performance: simple as black and white? Journal of the International Neuropsychological Society : JINS, 2013; 19(5): 583-93.
Pandina Gahan, Bilder Robert, Turkoz Ibrahim, Alphs Larry   Identification of clinically meaningful relationships among cognition, functionality, and symptoms in subjects with schizophrenia or schizoaffective disorder Schizophrenia research, 2013; 143(2-3): 312-8.
Bilder Robert M, Howe Andrew S, Sabb Fred W   Multilevel Models From Biology to Psychology: Mission Impossible? Journal of abnormal psychology, 2013; .
Chengappa K N Roy, Turkin Scott R, DeSanti Susan, Bowie Christopher R, Brar Jaspreet S, Schlicht Patricia J, Murphy Sherry L, Hetrick Michelle L, Bilder Robert, Fleet David   A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia Schizophrenia research, 2012; 142(1-3): 145-52.
Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Poldrack Russell Alan, Bookheimer Susan Yost, Bilder Robert Martin, Fernandez Vindia Gisela, Asarnow Robert Franklin   Deficits in probabilistic classification learning and liability for schizophrenia Psychiatry research, 2012; 200(2-3): 167-72.
Wellington Robin L, Bilder Robert M, Napolitano Barbara, Szeszko Philip R   Effects of age on prefrontal subregions and hippocampal volumes in young and middle-aged healthy humans Human brain mapping, 2012; 38(3): .
Bilder Robert M   Executive control: balancing stability and flexibility via the duality of evolutionary neuroanatomical trends Dialogues in clinical neuroscience, 2012; 14(1): 39-47.
Levine Andrew J, Sinsheimer Janet S, Bilder Robert, Shapshak Paul, Singer Elyse J   Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults Journal of clinical and experimental neuropsychology, 2012; 34(1): 78-91.
Szeszko Philip R, Narr Katherine L, Phillips Owen R, McCormack Joanne, Sevy Serge, Gunduz-Bruce Handan, Kane John M, Bilder Robert M, Robinson Delbert G   Magnetic resonance imaging predictors of treatment response in first-episode schizophrenia Schizophrenia bulletin, 2012; 38(3): 569-78.
Gruner Patricia, Christian Christopher, Robinson Delbert G, Sevy Serge, Gunduz-Bruce Handan, Napolitano Barbara, Bilder Robert M, Szeszko Philip R   Pituitary volume in first-episode schizophrenia Psychiatry research, 2012; 203(1): 100-2.
Clark Luke, Boxer Oren, Sahakian Barbara J, Bilder Robert M   Research methods: cognitive neuropsychological methods Handbook of clinical neurology, 2012; 106(3): 75-87.
Ventura Joseph, Reise Steven P, Keefe Richard S E, Hurford Irene M, Wood Rachel C, Bilder Robert M   The Cognitive Assessment Interview (CAI): Reliability and Validity of a Brief Interview-Based Measure of Cognition Schizophrenia bulletin, 2012; 14(1): .
Hurford Irene M, Marder Stephen R, Keefe Richard S E, Reise Steven P, Bilder Robert M   A brief cognitive assessment tool for schizophrenia: construction of a tool for clinicians Schizophrenia bulletin, 2011; 37(3): 538-45.
Reise Steven P, Ventura Joseph, Keefe Richard S E, Baade Lyle E, Gold James M, Green Michael F, Kern Robert S, Mesholam-Gately Raquelle, Nuechterlein Keith H, Seidman Larry J, Bilder Robert   Bifactor and item response theory analyses of interviewer report scales of cognitive impairment in schizophrenia Psychological assessment, 2011; 23(1): 245-61.
Cohen Jessica R, Asarnow Robert F, Sabb Fred W, Bilder Robert M, Bookheimer Susan Y, Knowlton Barbara J, Poldrack Russell A   Decoding continuous variables from neuroimaging data: basic and clinical applications Frontiers in neuroscience, 2011; 5(3): 75.
Ardekani Babak A, Tabesh Ali, Sevy Serge, Robinson Delbert G, Bilder Robert M, Szeszko Philip R   Diffusion tensor imaging reliably differentiates patients with schizophrenia from healthy volunteers Human brain mapping, 2011; 32(1): 1-9.
Bilder Robert M   Neuropsychology 3.0: evidence-based science and practice Journal of the International Neuropsychological Society : JINS, 2011; 17(1): 7-13.
Poldrack Russell A, Kittur Aniket, Kalar Donald, Miller Eric, Seppa Christian, Gil Yolanda, Parker D Stott, Sabb Fred W, Bilder Robert M   The cognitive atlas: toward a knowledge foundation for cognitive neuroscience Frontiers in neuroinformatics, 2011; 5(3): 17.
Bilder Robert M, Howe Andrew, Novak Nic, Sabb Fred W, Parker D Stott   The genetics of cognitive impairment in schizophrenia: a phenomic perspective Trends in cognitive sciences, 2011; 15(9): 428-35.
Lencz Todd, Szeszko Philip R, DeRosse Pamela, Burdick Katherine E, Bromet Evelyn J, Bilder Robert M, Malhotra Anil K   A schizophrenia risk gene, ZNF804A, influences neuroanatomical and neurocognitive phenotypes Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010; 35(11): 2284-91.
Cohen Jessica R, Asarnow Robert F, Sabb Fred W, Bilder Robert M, Bookheimer Susan Y, Knowlton Barbara J, Poldrack Russell A   A unique adolescent response to reward prediction errors Nature neuroscience, 2010; 13(6): 669-71.
Pandina Gahan J, Ness Seth, Polverejan Elena, Yuen Eric, Eerdekens Marielle, Bilder Robert M, Ford Lisa   Cognitive effects of topiramate in migraine patients aged 12 through 17 years Pediatric neurology, 2010; 42(3): 187-95.
Cohen Jessica R, Asarnow Robert F, Sabb Fred W, Bilder Robert M, Bookheimer Susan Y, Knowlton Barbara J, Poldrack Russell A   Decoding developmental differences and individual variability in response inhibition through predictive analyses across individuals Frontiers in human neuroscience, 2010; 4(1-3): 47.
Ghahremani Dara G, Monterosso John, Jentsch J David, Bilder Robert M, Poldrack Russell A   Neural components underlying behavioral flexibility in human reversal learning Cerebral cortex (New York, N.Y. : 1991), 2010; 20(8): 1843-52.
Ventura Joseph, Reise Steven P, Keefe Richard S E, Baade Lyle E, Gold James M, Green Michael F, Kern Robert S, Mesholam-Gately Raquelle, Nuechterlein Keith H, Seidman Larry J, Bilder Robert M   The Cognitive Assessment Interview (CAI): development and validation of an empirically derived, brief interview-based measure of cognition Schizophrenia research, 2010; 121(1-3): 24-31.
Bilder Robert M, Sabb Fred W, Parker D Stott, Kalar Donald, Chu Wesley W, Fox Jared, Freimer Nelson B, Poldrack Russell A   Cognitive ontologies for neuropsychiatric phenomics research Cognitive neuropsychiatry, 2009; 14(4-5): 419-50.
Narr Katherine L, Szeszko Philip R, Lencz Todd, Woods Roger P, Hamilton Liberty S, Phillips Owen, Robinson Delbert, Burdick Katherine E, DeRosse Pamela, Kucherlapati Raju, Thompson Paul M, Toga Arthur W, Malhotra Anil K, Bilder Robert M   DTNBP1 is associated with imaging phenotypes in schizophrenia Human brain mapping, 2009; 30(11): 3783-94.
Lee Buyean, London Edythe D, Poldrack Russell A, Farahi Judah, Nacca Angelo, Monterosso John R, Mumford Jeanette A, Bokarius Andrew V, Dahlbom Magnus, Mukherjee Jogeshwar, Bilder Robert M, Brody Arthur L, Mandelkern Mark A   Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(47): 14734-40.
Bilder Robert M   The neuropsychology of schizophrenia circa 2009 Neuropsychology review, 2009; 19(3): 277-9.
Coscia Denise M, Narr Katherine L, Robinson Delbert G, Hamilton Liberty S, Sevy Serge, Burdick Katherine E, Gunduz-Bruce Handan, McCormack Joanne, Bilder Robert M, Szeszko Philip R   Volumetric and shape analysis of the thalamus in first-episode schizophrenia Human brain mapping, 2009; 30(4): 1236-45.
Harvey Philip D, Sacchetti Emilio, Galluzzo Alessandro, Romeo Fabio, Gorini Barbara, Bilder Robert M, Loebel Antony D   A randomized double-blind comparison of ziprasidone vs. clozapine for cognition in patients with schizophrenia selected for resistance or intolerance to previous treatment Schizophrenia research, 2008; 105(1-3): 138-43.
Szeszko Philip R, Robinson Delbert G, Ashtari Manzar, Vogel Joshua, Betensky Julia, Sevy Serge, Ardekani Babak A, Lencz Todd, Malhotra Anil K, McCormack Joanne, Miller Rachel, Lim Kelvin O, Gunduz-Bruce Handan, Kane John M, Bilder Robert M   Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008; 33(5): 976-84.
Ventura Joseph, Cienfuegos Angel, Boxer Oren, Bilder Robert   Clinical global impression of cognition in schizophrenia (CGI-CogS): reliability and validity of a co-primary measure of cognition Schizophrenia research, 2008; 106(1): 59-69.
Shattuck David W, Mirza Mubeena, Adisetiyo Vitria, Hojatkashani Cornelius, Salamon Georges, Narr Katherine L, Poldrack Russell A, Bilder Robert M, Toga Arthur W   Construction of a 3D probabilistic atlas of human cortical structures NeuroImage, 2008; 39(3): 1064-80.
Szeszko Philip R, Hodgkinson Colin A, Robinson Delbert G, Derosse Pamela, Bilder Robert M, Lencz Todd, Burdick Katherine E, Napolitano Barbara, Betensky Julia D, Kane John M, Goldman David, Malhotra Anil K   DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia Biological psychology, 2008; 79(1): 103-10.
Luders Eileen, Narr Katherine L, Bilder Robert M, Szeszko Philip R, Gurbani Mala N, Hamilton Liberty, Toga Arthur W, Gaser Christian   Mapping the relationship between cortical convolution and intelligence: effects of gender Cerebral cortex (New York, N.Y. : 1991), 2008; 18(9): 2019-26.
Betensky Julia D, Robinson Delbert G, Gunduz-Bruce Handan, Sevy Serge, Lencz Todd, Kane John M, Malhotra Anil K, Miller Rachel, McCormack Joanne, Bilder Robert M, Szeszko Philip R   Patterns of stress in schizophrenia Psychiatry research, 2008; 160(1): 38-46.
Bilder Robert M   Phenomics: building scaffolds for biological hypotheses in the post-genomic era Biological psychiatry, 2008; 63(5): 439-40.
Foerde Karin, Poldrack Russell A, Khan Barbara J, Sabb Fred W, Bookheimer Susan Y, Bilder Robert M, Guthrie Don, Granholm Eric, Nuechterlein Keith H, Marder Stephen R, Asarnow Robert F   Selective corticostriatal dysfunction in schizophrenia: examination of motor and cognitive skill learning Neuropsychology, 2008; 22(1): 100-9.
Szeszko Philip R, Robinson Delbert G, Sevy Serge, Kumra Sanjiv, Rupp Claudia I, Betensky Julia D, Lencz Todd, Ashtari Manzar, Kane John M, Malhotra Anil K, Gunduz-Bruce Handan, Napolitano Barbara, Bilder Robert M   Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia The British journal of psychiatry : the journal of mental science, 2007; 190(1): 230-6.
Narr Katherine L, Bilder Robert M, Luders Eileen, Thompson Paul M, Woods Roger P, Robinson Delbert, Szeszko Philip R, Dimtcheva Teodora, Gurbani Mala, Toga Arthur W   Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia NeuroImage, 2007; 34(3): 939-48.
Hamilton Liberty S, Narr Katherine L, Luders Eileen, Szeszko Philip R, Thompson Paul M, Bilder Robert M, Toga Arthur W   Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia Neuroreport, 2007; 18(14): 1427-31.
Gunduz-Bruce Handan, Narr Katherine L, Gueorguieva Ralitza, Toga Arthur W, Szeszko Philip R, Ashtari Manzar, Robinson Delbert G, Sevy Serge, Kane John M, Bilder Robert M   CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia Psychiatry research, 2007; 155(1): 57-66.
Gunduz-Bruce Handan, Szeszko Philip R, Gueorguieva Ralitza, Ashtari Manzar, Robinson Delbert G, Kane John M, Bilder Robert M   Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia Schizophrenia research, 2007; 94(1-3): 281-7.
Keefe Richard S E, Bilder Robert M, Davis Sonia M, Harvey Philip D, Palmer Barton W, Gold James M, Meltzer Herbert Y, Green Michael F, Capuano George, Stroup T Scott, McEvoy Joseph P, Swartz Marvin S, Rosenheck Robert A, Perkins Diana O, Davis Clarence E, Hsiao John K, Lieberman Jeffrey A, Lieberman Jeffrey A, Lieberman Jeffrey A   Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial Archives of general psychiatry, 2007; 64(6): 633-47.
Luders Eileen, Narr Katherine L, Bilder Robert M, Thompson Paul M, Szeszko Philip R, Hamilton Liberty, Toga Arthur W   Positive correlations between corpus callosum thickness and intelligence NeuroImage, 2007; 37(4): 1457-64.
Narr Katherine L, Woods Roger P, Thompson Paul M, Szeszko Philip, Robinson Delbert, Dimtcheva Teodora, Gurbani Mala, Toga Arthur W, Bilder Robert M   Relationships between IQ and regional cortical gray matter thickness in healthy adults Cerebral cortex (New York, N.Y. : 1991), 2007; 17(9): 2163-71.
Pandina Gahan J, Bilder Robert, Harvey Philip D, Keefe Richard S E, Aman Michael G, Gharabawi Georges   Risperidone and cognitive function in children with disruptive behavior disorders Biological psychiatry, 2007; 62(3): 226-34.
Sabb Fred W, Bilder Robert M, Chou Maggie, Bookheimer Susan Y   Working memory effects on semantic processing: priming differences in pars orbitalis NeuroImage, 2007; 37(1): 311-22.
Hoptman Matthew J, Volavka Jan, Czobor Pál, Gerig Guido, Chakos Miranda, Blocher Joseph, Citrome Leslie L, Sheitman Brain, Lindenmayer Jean-Pierre, Lieberman Jeffrey A, Bilder Robert M   Aggression and quantitative MRI measures of caudate in patients with chronic schizophrenia or schizoaffective disorder The Journal of neuropsychiatry and clinical neurosciences, 2006; 18(4): 509-15.
Keefe Richard S E, Bilder Robert M, Harvey Philip D, Davis Sonia M, Palmer Barton W, Gold James M, Meltzer Herbert Y, Green Michael F, Miller Del D, Canive Jose M, Adler Lawrence W, Manschreck Theo C, Swartz Marvin, Rosenheck Robert, Perkins Diana O, Walker Trina M, Stroup T Scott, McEvoy Joseph P, Lieberman Jeffrey A   Baseline neurocognitive deficits in the CATIE schizophrenia trial Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006; 31(9): 2033-46.
Bilder Robert M, Reiter Gail, Bates Jay, Lencz Todd, Szeszko Philip, Goldman Robert S, Robinson Delbert, Lieberman Jeffrey A, Kane John M   Cognitive development in schizophrenia: follow-back from the first episode Journal of clinical and experimental neuropsychology, 2006; 28(2): 270-82.
Szeszko Philip R, Betensky Julia D, Mentschel Claudia, Gunduz-Bruce Handan, Lencz Todd, Ashtari Manzar, Malhotra Anil K, Bilder Robert M   Increased stress and smaller anterior hippocampal volume Neuroreport, 2006; 17(17): 1825-8.
Narr Katherine L, Bilder Robert M, Woods Roger P, Thompson Paul M, Szeszko Philip, Robinson Delbert, Ballmaier Martina, Messenger Bradley, Wang YungPing, Toga Arthur W   Regional specificity of cerebrospinal fluid abnormalities in first episode schizophrenia Psychiatry research, 2006; 146(1): 21-33.
Narr Katherine L, Toga Arthur W, Szeszko Philip, Thompson Paul M, Woods Roger P, Robinson Delbert, Sevy Serge, Wang YungPing, Schrock Karen, Bilder Robert M   Cortical thinning in cingulate and occipital cortices in first episode schizophrenia Biological psychiatry, 2005; 58(1): 32-40.
Narr Katherine L, Bilder Robert M, Toga Arthur W, Woods Roger P, Rex David E, Szeszko Philip R, Robinson Delbert, Sevy Serge, Gunduz-Bruce Handan, Wang Yung-Ping, DeLuca Heather, Thompson Paul M   Mapping cortical thickness and gray matter concentration in first episode schizophrenia Cerebral cortex (New York, N.Y. : 1991), 2005; 15(6): 708-19.
Rhinewine Joseph P, Lencz Todd, Thaden Emily P, Cervellione Kelly L, Burdick Katherine E, Henderson Inika, Bhaskar Shree, Keehlisen Lynda, Kane John, Kohn Nina, Fisch Gene S, Bilder Robert M, Kumra Sanjiv   Neurocognitive profile in adolescents with early-onset schizophrenia: clinical correlates Biological psychiatry, 2005; 58(9): 705-12.
Rupp Claudia I, Fleischhacker W Wolfgang, Kemmler Georg, Kremser Christian, Bilder Robert M, Mechtcheriakov Sergei, Szeszko Philip R, Walch Thomas, Scholtz Arne W, Klimbacher Martina, Maier Claudia, Albrecht Gudrun, Lechner-Schoner Theresia, Felber Stefan, Hinterhuber Hartmann   Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia Schizophrenia research, 2005; 74(2-3): 149-61.
Hoptman Matthew J, Volavka Jan, Weiss Elisabeth M, Czobor Pál, Szeszko Philip R, Gerig Guido, Chakos Miranda, Blocher Joseph, Citrome Leslie L, Lindenmayer Jean-Pierre, Sheitman Brian, Lieberman Jeffrey A, Bilder Robert M   Quantitative MRI measures of orbitofrontal cortex in patients with chronic schizophrenia or schizoaffective disorder Psychiatry research, 2005; 140(2): 133-45.
Szeszko Philip R, Ardekani Babak A, Ashtari Manzar, Kumra Sanjiv, Robinson Delbert G, Sevy Serge, Gunduz-Bruce Handan, Malhotra Anil K, Kane John M, Bilder Robert M, Lim Kelvin O   White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study The American journal of psychiatry, 2005; 162(3): 602-5.
Szeszko Philip R, Ardekani Babak A, Ashtari Manzar, Malhotra Anil K, Robinson Delbert G, Bilder Robert M, Lim Kelvin O   White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study Archives of general psychiatry, 2005; 62(7): 782-90.
McClure Erin B, Monk Christopher S, Nelson Eric E, Zarahn Eric, Leibenluft Ellen, Bilder Robert M, Charney Dennis S, Ernst Monique, Pine Daniel S   A developmental examination of gender differences in brain engagement during evaluation of threat Biological psychiatry, 2004; 55(11): 1047-55.
Narr Katherine L, Bilder Robert M, Kim Sharon, Thompson Paul M, Szeszko Philip, Robinson Delbert, Luders Eileen, Toga Arthur W   Abnormal gyral complexity in first-episode schizophrenia Biological psychiatry, 2004; 55(8): 859-67.
Nolan Karen A, Bilder Robert M, Lachman Herbert M, Volavka Jan   Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility The American journal of psychiatry, 2004; 161(2): 359-61.
Volavka Jan, Bilder Robert, Nolan Karen   Catecholamines and aggression: the role of COMT and MAO polymorphisms Annals of the New York Academy of Sciences, 2004; 1036(1): 393-8.
Volavka Jan, Bilder Robert M, Lachman Herbert M   Genetic linkage for schizophrenia? The American journal of psychiatry, 2004; 161(6): 1134-5; author reply 1135-6.
Szeszko Philip R, Bates John, Robinson Delbert, Kane John, Bilder Robert M   Investigation of unirhinal olfactory identification in antipsychotic-free patients experiencing a first-episode schizophrenia Schizophrenia research, 2004; 67(2-3): 219-25.
Ashtari Manzar, Lencz Todd, Zuffante Paula, Bilder Robert, Clarke Tana, Diamond Alan, Kane John, Szeszko Philip   Left middle temporal gyrus activation during a phonemic discrimination task Neuroreport, 2004; 15(3): 389-93.
Narr Katherine L, Thompson Paul M, Szeszko Philip, Robinson Delbert, Jang Seonah, Woods Roger P, Kim Sharon, Hayashi Kiralee M, Asunction Dina, Toga Arthur W, Bilder Robert M   Regional specificity of hippocampal volume reductions in first-episode schizophrenia NeuroImage, 2004; 21(4): 1563-75.
Robinson Delbert G, Woerner Margaret G, McMeniman Marjorie, Mendelowitz Alan, Bilder Robert M   Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder The American journal of psychiatry, 2004; 161(3): 473-9.
Bilder Robert M, Volavka Jan, Lachman Herbert M, Grace Anthony A   The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004; 29(11): 1943-61.
Monk Christopher S, McClure Erin B, Nelson Eric E, Zarahn Eric, Bilder Robert M, Leibenluft Ellen, Charney Dennis S, Ernst Monique, Pine Daniel S   Adolescent immaturity in attention-related brain engagement to emotional facial expressions NeuroImage, 2003; 20(1): 420-8.
Giovannetti Tania, Goldstein Rita Z, Schullery Matthew, Barr William B, Bilder Robert M   Category fluency in first-episode schizophrenia Journal of the International Neuropsychological Society : JINS, 2003; 9(3): 384-93.
Fan Jin, Gay Snodgrass Joan, Bilder Robert M   Functional magnetic resonance imaging of source versus item memory Neuroreport, 2003; 14(17): 2275-81.
Lencz Todd, Bilder Robert M, Turkel Elihu, Goldman Robert S, Robinson Delbert, Kane John M, Lieberman Jeffrey A   Impairments in perceptual competency and maintenance on a visual delayed match-to-sample test in first-episode schizophrenia Archives of general psychiatry, 2003; 60(3): 238-43.
Szeszko Philip R, Gunning-Dixon Faith, Goldman Robert S, Bates John, Ashtari Manzar, Snyder Peter J, Lieberman Jeffrey A, Bilder Robert M   Lack of normal association between cerebellar volume and neuropsychological functions in first-episode schizophrenia The American journal of psychiatry, 2003; 160(10): 1884-7.
Keefe Richard S E, Mohs Richard C, Bilder Robert M, Harvey Philip D, Green Michael F, Meltzer Herbert Y, Gold James M, Sano Mary   Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale Schizophrenia bulletin, 2003; 29(1): 45-55.
Szeszko Philip R, Gunning-Dixon Faith, Ashtari Manzar, Snyder Peter J, Lieberman Jeffrey A, Bilder Robert M   Reversed cerebellar asymmetry in men with first-episode schizophrenia Biological psychiatry, 2003; 53(5): 450-9.
Szeszko Philip R, Vogel Joshua, Ashtari Manzar, Malhotra Anil K, Bates John, Kane John M, Bilder Robert M, Frevert Theresa, Lim Kelvin   Sex differences in frontal lobe white matter microstructure: a DTI study Neuroreport, 2003; 14(18): 2469-73.
Szeszko Philip R, Goldberg Ethan, Gunduz-Bruce Handan, Ashtari Manzar, Robinson Delbert, Malhotra Anil K, Lencz Todd, Bates John, Crandall David T, Kane John M, Bilder Robert M   Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia The American journal of psychiatry, 2003; 160(12): 2190-7.
Gunduz Handan, Wu Huwei, Ashtari Manzar, Bogerts Bernhard, Crandall David, Robinson Delbert G, Alvir Jose, Lieberman Jeffrey, Kane John, Bilder Robert   Basal ganglia volumes in first-episode schizophrenia and healthy comparison subjects Biological psychiatry, 2002; 51(10): 801-8.
Hoptman Matthew J, Volavka Jan, Johnson Glyn, Weiss Elisabeth, Bilder Robert M, Lim Kelvin O   Frontal white matter microstructure, aggression, and impulsivity in men with schizophrenia: a preliminary study Biological psychiatry, 2002; 52(1): 9-14.
Ardekani Babak A, Choi Steven J, Hossein-Zadeh Gholam Ali, Porjesz Bernice, Tanabe Jody L, Lim Kelvin O, Bilder Robert, Helpern Joseph A, Begleiter Henri   Functional magnetic resonance imaging of brain activity in the visual oddball task Brain research. Cognitive brain research, 2002; 14(3): 347-56.
Citrome Leslie, Bilder Robert M, Volavka Jan   Managing treatment-resistant schizophrenia: evidence from randomized clinical trials Journal of psychiatric practice, 2002; 8(4): 205-15.
Goldstein Rita Z, Giovannetti Tania, Schullery Mathew, Zuffante Paula A, Lieberman Jeffrey A, Robinson Delbert G, Barr William B, Bilder Robert M   Neurocognitive correlates of response to treatment in formal thought disorder in patients with first-episode schizophrenia Neuropsychiatry, neuropsychology, and behavioral neurology, 2002; 15(2): 88-98.
Bilder Robert M, Volavka Jan, Czobor Pál, Malhotra Anil K, Kennedy James L, Ni Xingqun, Goldman Robert S, Hoptman Matthew J, Sheitman Brian, Lindenmayer Jean-Pierre, Citrome Leslie, McEvoy Joseph P, Kunz Michal, Chakos Miranda, Cooper Thomas B, Lieberman Jeffrey A   Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia Biological psychiatry, 2002; 52(7): 701-7.
Bilder Robert M, Goldman Robert S, Volavka Jan, Czobor Pal, Hoptman Matthew, Sheitman Brian, Lindenmayer Jean-Pierre, Citrome Leslie, McEvoy Joseph, Kunz Michal, Chakos Miranda, Cooper Thomas B, Horowitz Terri L, Lieberman Jeffrey A   Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder The American journal of psychiatry, 2002; 159(6): 1018-28.
Pine Daniel S, Grun Joseph, Maguire Eleanor A, Burgess Neil, Zarahn Eric, Koda Vivian, Fyer Abby, Szeszko Philip R, Bilder Robert M   Neurodevelopmental aspects of spatial navigation: a virtual reality fMRI study NeuroImage, 2002; 15(2): 396-406.
Szeszko Philip R, Strous Rael D, Goldman Robert S, Ashtari Manzar, Knuth Kevin H, Lieberman Jeffrey A, Bilder Robert M   Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia The American journal of psychiatry, 2002; 159(2): 217-26.
Malhotra Anil K, Bates John A, Jaeger Judith, Petrides Georgios, Robinson Delbert G, Bilder Robert M, Nassauer Katharine W   No evidence for phenotypic variation between probands in case-control versus family-based association studies of schizophrenia American journal of medical genetics, 2002; 114(5): 509-11.
Robinson Delbert G, Woerner Margaret G, Alvir Jose Ma J, Bilder Robert M, Hinrichsen Gregory A, Lieberman Jeffrey A   Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder Schizophrenia research, 2002; 57(2-3): 209-19.
Weiss Elisabeth M, Bilder Robert M, Fleischhacker W Wolfgang   The effects of second-generation antipsychotics on cognitive functioning and psychosocial outcome in schizophrenia Psychopharmacology, 2002; 162(1): 11-7.
Bilder Robert M, Sugar Catherine A, Hellemann Gerhard S   Cumulative false positive rates given multiple performance validity tests: commentary on Davis and Millis (2014) and Larrabee (2014) The Clinical neuropsychologist, 2014; 28(8): 1212-23.
Miller Justin B, Schoenberg Mike R, Bilder Robert M   Consolidated Standards of Reporting Trials (CONSORT): considerations for neuropsychological research The Clinical neuropsychologist, 2014; 28(4): 575-99.
Haut Kristen M, Karlsgodt Katherine H, Bilder Robert M, Congdon Eliza, Freimer Nelson B, London Edythe D, Sabb Fred W, Ventura Joseph, Cannon Tyrone D   Memory systems in schizophrenia: Modularity is preserved but deficits are generalized Schizophrenia research, 2015; .
Sabb Fred W, Hellemann Gerhard, Lau Deanna, Vanderlan Jessica R, Cohen Heather J, Bilder Robert M, McCracken James T   High-throughput cognitive assessment using BrainTest.org: examining cognitive control in a family cohort Brain and behavior, 2013; 3(5): 552-61.
Bilder Robert M, Knudsen Kendra S   Creative cognition and systems biology on the edge of chaos Frontiers in psychology, 2014; 5(4): 1104.
Burton Cynthia Z, Vella Lea, Kelsoe John R, Bilder Robert M, Twamley Elizabeth W   Catechol-O-methyltransferase genotype and response to Compensatory Cognitive Training in outpatients with schizophrenia Psychiatric genetics, 2015; 25(3): 131-4.
Congdon Eliza, Bato Angelica A, Schonberg Tom, Mumford Jeanette A, Karlsgodt Katherine H, Sabb Fred W, London Edythe D, Cannon Tyrone D, Bilder Robert M, Poldrack Russell A   Differences in neural activation as a function of risk-taking task parameters Frontiers in neuroscience, 2013; 7(5): 173.
Robertson Chelsea L, Ishibashi Kenji, Mandelkern Mark A, Brown Amira K, Ghahremani Dara G, Sabb Fred, Bilder Robert, Cannon Tyrone, Borg Jacqueline, London Edythe D   Striatal D1- and D2-type dopamine receptors are linked to motor response inhibition in human subjects The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015; 35(15): 5990-7.
Anderson Ariana, Wilcox Marsha, Savitz Adam, Chung Hearee, Li Qingqin, Salvadore Giacomo, Wang Dai, Nuamah Isaac, Riese Steven P, Bilder Robert M   Sparse factors for the positive and negative syndrome scale: which symptoms and stage of illness? Psychiatry research, 2015; 225(3): 283-90.
Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Bookheimer Susan Yost, Bilder Robert Martin, Fernandez Vindia Gisela, Asarnow Robert Franklin   Cognitive correlates of gray matter abnormalities in adolescent siblings of patients with childhood-onset schizophrenia Schizophrenia research, 2015; 161(2-3): 345-50.
Twamley Elizabeth W, Hua Jessica P Y, Burton Cynthia Z, Vella Lea, Chinh Kelly, Bilder Robert M, Kelsoe John R   Effects of COMT genotype on cognitive ability and functional capacity in individuals with schizophrenia Schizophrenia research, 2014; 159(1): 114-7.
Bilder Robert M   Finding pieces to the puzzle of brain structure in schizophrenia Biological psychiatry, 2014; 76(6): 432-3.
Wagshal Dana, Knowlton Barbara Jean, Suthana Nanthia Ananda, Cohen Jessica Rachel, Poldrack Russel Alan, Bookheimer Susan Yost, Bilder Robert Martin, Asarnow Robert Franklin   Evidence for corticostriatal dysfunction during cognitive skill learning in adolescent siblings of patients with childhood-onset schizophrenia Schizophrenia bulletin, 2014; 40(5): 1030-9.
White Corey N, Congdon Eliza, Mumford Jeanette A, Karlsgodt Katherine H, Sabb Fred W, Freimer Nelson B, London Edythe D, Cannon Tyrone D, Bilder Robert M, Poldrack Russell A   Decomposing decision components in the stop-signal task: a model-based approach to individual differences in inhibitory control Journal of cognitive neuroscience, 2014; 26(8): 1601-14.
Thakkar Katharine N, Congdon Eliza, Poldrack Russell A, Sabb Fred W, London Edythe D, Cannon Tyrone D, Bilder Robert M   Women are more sensitive than men to prior trial events on the Stop-signal task British journal of psychology (London, England : 1953), 2014; 105(2): 254-72.
Congdon Eliza, Altshuler Lori L, Mumford Jeanette A, Karlsgodt Katherine H, Sabb Fred W, Ventura Joseph, McGough James J, London Edythe D, Cannon Tyrone D, Bilder Robert M, Poldrack Russell A   Neural activation during response inhibition in adult attention-deficit/hyperactivity disorder: preliminary findings on the effects of medication and symptom severity Psychiatry research, 2014; 222(1-2): 17-28.
McCarty Catherine A, Huggins Wayne, Aiello Allison E, Bilder Robert M, Hariri Ahmad, Jernigan Terry L, Newman Erik, Sanghera Dharambir K, Strauman Timothy J, Zeng Yi, Ramos Erin M, Junkins Heather A, Junkins Heather A   PhenX RISING: real world implementation and sharing of PhenX measures BMC medical genomics, 2014; 7(1-2): 16.
Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Poldrack Russell Alan, Bookheimer Susan Yost, Bilder Robert Martin, Asarnow Robert Franklin   Impaired automatization of a cognitive skill in first-degree relatives of patients with schizophrenia Psychiatry research, 2014; 215(2): 294-9.
Helfinstein Sarah M, Schonberg Tom, Congdon Eliza, Karlsgodt Katherine H, Mumford Jeanette A, Sabb Fred W, Cannon Tyrone D, London Edythe D, Bilder Robert M, Poldrack Russell A   Predicting risky choices from brain activity patterns Proceedings of the National Academy of Sciences of the United States of America, 2014; 111(7): 2470-5.
Lenartowicz Agatha, Delorme Arnaud, Walshaw Patricia D, Cho Alex L, Bilder Robert M, McGough James J, McCracken James T, Makeig Scott, Loo Sandra K   Electroencephalography correlates of spatial working memory deficits in attention-deficit/hyperactivity disorder: vigilance, encoding, and maintenance The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(4): 1171-82.
Parker Douglass Stott, Congdon Eliza, Bilder Robert M   Hypothesis exploration with visualization of variance BioData mining, 2014; 7(4): 11.

Gal Bitan, Ph.D.

Biography

Gal Bitan got his PhD in organic chemistry from the Hebrew University of Jerusalem, Israel. Dr. Bitan’s graduate work on unnatural amino acids and non-conventional peptide cyclization methodologies led him to postdoctoral studies on the structural biology of ligand-receptor systems including integrins and G protein-coupled receptors at Clark University, Worcester, MA and Beth Israel-Deaconess Medical Center/Harvard Medical School, Boston, MA. Dr. Bitan then moved on to tackle the problem of protein misfolding and aggregation, which is involved in over 30 devastating diseases, such as Alzheimer’s disease, Parkinson’s disease, prion diseases (e.g., Mad Cow disease), amyotrophic lateral sclerosis (Lou Gherig’s disease), and type II diabetes. Working at Brigham and Women’s Hospital/Harvard Medical School, Boston, MA, Dr. Bitan has made fundamental contributions to the study of early events in the pathologic cascades that cause Alzheimer’s disease. In Alzheimer’s disease, the amyloid ß-protein (Aß) self-associates to form a variety of oligomeric and polymeric structures with potent neurotoxic activities. In particular, Aß oligomers have been implicated as the probable cause of Alzheimer’s disease. Dr. Bitan introduced the use of novel photochemical protein cross-linking techniques for investigation of Aß assembly and discovered one of the earliest oligomers in the assembly cascade, the paranucleus. In 2004, Dr. Bitan joined UCLA where he is currently a Professor of Neurology. His research program is focused on translational science geared at developing novel, mechanism-based diagnostic and therapeutic tools for neurodegenerative diseases, including Alzheimer’s disease and other tauopathies, Parkinson’s disease, multiple system atrophy, and amyotrophic lateral sclerosis.