Posts classified under: Departments

Xian-Jie Yang, Ph.D.

Biography

Xian-Jie Yang is a developmental biologist, who has served on the UCLA School of Medicine faculty since she joined the Department of Ophthalmology in 1996. She is a member of the Molecular Biology Institute, Brain Research Institute, and has become an associate professor in 2003. Dr, Yang obtained her B.S in biology from Beijing Normal University and her Ph.D. from Cornell University in Biochemistry, Cell and Molecular Biology after studying transcription regulation. She pursued her postdoctoral training at Harvard University and Harvard Medical School working on vertebrate neural development. Her research centers on development and diseases of the vertebrate retina, in particular growth factor signaling mechanisms during normal neural differentiation and neuronal survival in retinal degeneration. Her laboratory is also developing cellular and molecular therapies for inherited retinal diseases.

Lars Dreier, Ph.D.

Biography

Dr. Lars Dreier joined the Department of Neurobiology as an Assistant Professor in 2006. Lars did his Ph.D. work in the Department of Cell Biology, Harvard Medical School, Boston, in the lab of Tom Rapoport, reconstituting the transport of secretory proteins through the Endoplasmic Reticulum (ER) membrane and characterizing the formation of the ER in vitro. In 2000, he joined the lab of Josh Kaplan at the University of California, Berkeley, where he started to work on ubiquitin-dependent regulation of glutamate receptors in C. elegans . Lars moved with the Kaplan lab back to Boston in 2002.

Publications

A selected list of publications:

Sun Yu, Vashisht Ajay A, Tchieu Jason, Wohlschlegel James A, Dreier Lars   Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy The Journal of biological chemistry, 2012; 287(48): 40652-60.
Wang, J, G.W. Farr, D.H. Hall, F. Li, K. Furtak, L. Dreier, A.L. Horwich   An ALS-Linked Mutant SOD1 Produces a Locomotor Defect Associated with Aggregation and Synaptic Dysfunction When Expressed in Neurons of Caenorhabditis elegans PLoS Genetics, 2009; 5(1): .
Burbea, M.* Dreier, L.* Dittman, J. S. Grunwald, M. E. Kaplan, J. M.   Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans Neuron, 2002; 35: 107-20, * contributed equally.
Felbor, U. Dreier, L. Bryant, R. A. Ploegh, H. L. Olsen, B. R. Mothes, W.   Secreted cathepsin L generates endostatin from collagen XVIII Embo J, 2000; 19(6): 1187-94.
Panzner, S. Dreier, L. Hartmann, E. Kostka, S. Rapoport, T. A.   Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p Cell, 1995; 81(4): 561-70.

Dahlia Zaidel, Ph.D.

Biography

Charting the morphology and cytoarchitecture of the left and right hippocampus in postmortem tissue. Neurology, biology, and neuropsychology of beauty and aesthetics. Research Description: Cognitive neuropsychology; function localization in the human brain. Conceptual organization in long term semantic memory. Hemispheric specialization. Beauty and face. Symmetry and asymmetry in human faces. Click here to go to her web site