Posts classified under: L

Loes Olde Loohuis, Ph.D.

Dr. Loes Olde Loohuis’ research focuses on elucidating the underlying molecular mechanisms of severe mental illness, in particular schizophrenia and bipolar disorder, by utilizing and developing computational approaches to leverage  multi-level data (including psychiatric phenotypes, health records and molecular phenotypes).

Wentai Liu, Ph.D.

Publications

A selected list of publications:

M. Chae, Z. Yang, W. Liu   A 128-Channel 6mW Wireless Neural Recording IC with On-the-fly Spike Sorting and UWB transmitter, IEEE Trans. on Neural Engineering and Rehabilitation Engineering, ; 14(9): 2009.
Xu, X. Wu, K. Islam, X. Huang, M. Je, W. Liu, and Z. Yang   A New System Architecture for Future Long-Term High-Density Neural Recording, IEEE Trans. On Biomedical Engineering, 2012; .
W. Liu, et al.   An experimental platform for retinal prosthesis – system perspective and performance evaluation, IEEE Trans. on Biomedical Circuits and Systems, 2012; .
G. Wang, P. Wang, Y. Tang, and W. Liu   Analysis of dual band power and data telemetry for biomedical implants, IEEE Trans. on Biomedical Circuits and Systems, 2012; .
Z. Yang, M. Keshtkaran, Y. Zhou, J. Xu, V. Pikov, C. Guan, and W. Liu   Threshold Estimation for In-Vivo Neural Spike Detection, Journal of Neural Engineering, 2012; .
Z. Yang, E. Keefer, Q. Zhao, L. Hoang, and W. Liu   1/f Neural Noise Reduction and Spike Feature Extraction using a Subset of Informative Samples, Annals of Biomedical Engineering, 2011; 39(4): 1264-1277.
K. Huang, Y. Zhou, X. Wu, W. Liu, and Zhi Yang   Design and Optimization of Inductive Power Link for Biomedical Applications, Intech, 2011; .
K. Chen, Z. Yang, L. Hoang, J. Weiland, M. Humayun and W. Liu   An Integrated 256-channel Epiretinal Prosthesis, IEEE J. of Solid State Circuits, 2010; 45(9): .
Z. Yang, Q. Zhao, E. Keefer and W. Liu   Noise Characterization, Modeling, and Reduction for In Vivo Neural Recording, Advances in Neural Information Processing Systems , 2010; 2160-2168.
E. Basham, Z. Yang, and W. Liu   Circuit and Coil Design for In Vitro Magnetic Neural Stimulation Systems, IEEE Transactions on Biomedical Circuits and Systems (TBCAS), 2009; 3: 321-331.
Z. Yang, Q. Zhao and W. Liu   Improving Spike Separation Using Waveform Derivative, Journal of Neural Engineering, 2009; 6(4): .
A. Rosen, W. Liu, and M. Tohgi   MTT Special Issue on RF and Microwave Techniques for Wireless Implants and Biomedical Applications: Guest Editorial, IEEE Trans. on Microwave Theory and Techniques, 2009; 57(9): .
Z. Yang, Q. Zhao and W. Liu   Neural Signal Classification Using a Simplified Feature Set with Energy Based Non-parametric Clustering, Neurocomputing, 2009; 73: 412-422.
Z. Yang, Q. Zhao and W. Liu   Spike Feature Extraction Using Informative Samples, Spotlight presentation, Advances in Neural Information Processing Systems (NIPS21), 2009; 1865-1872.
M. Zhou and W. Liu   A Non-Coherent DPSK Data Receiver with Interference Cancellation for Dual-Band Transcutaneous Telemetries, IEEE Journal of Solid-State Circuits, 2008; .
M. Chae, and W. Liu,   Design Optimization for Integrated Neural Recording Systems, IEEE Journal of Solid-State Circuits, 2008; .
W. Liu, M. Humayun, and M. Liker   Implantable Biomimetic Microelectronics Systems, IEEE Proceedings, 2008; 96(7): 1073-1075.
W. Liu, M. Humayun, and M. Liker   Special Issue on Implantable Biomimetic Microelectronics Systems: Guest Editorial, Proceeding of IEEE, 2008; 96(7): .
K. Cockerham, W. Liu, L. Crow, M. Sivaprakasam, A. Olmos, M. Oehleberg, O. Pantchenko and S. Aro,   The Application of Nano-Technology and Engineering in Medicine: A New Paradigm for Facial Muscle Reanimation, Expert Review of Medical Devices, 2008; .
K. Cockerham, W. Liu, L. Crow, M. Sivaprakasam, A. Olmos, M. Oehleberg, O. Pantchenko and S. Aro,   The Application of Nano-Technology and Engineering in Medicine: A New Paradigm for Facial Muscle Reanimation, Expert Review of Medical Devices, 2008; .
M. R. Yuce and W. Liu   Design and performance of a wideband sub-sampling front-ends for multi-standard software radios, International Journal of Electronics and Communications Elsevier, 2007; .
Z.Yang, W. Liu and E. Basham   Optimization of Coils for Biomedical Applications,”, IEEE Transactions on Magnetics, 2007; 43: 3851-3860.
M. R. Yuce, W. Liu, J. Damiano, B. Bharat, P. D. Franzon and N. S. Dogan   SOI CMOS implementation of a multirate PSK receiver for space communications, IEEE Transactions on Circuits and Systems I, 2007; .
R. Bashirullah, W. Liu, and R. Cavin   A 16Gb/s Adaptive Bandwidth Bus Based on Hybrid Current/Voltage Mode Signaling Repeaters, IEEE Journal of Solid-State Circuits, 2006; 41: 461-473.
W. Liu and M. Sivaprakasam   IC Technology Challenges for Implantable Devices, Future Fab International, 2006; 20: 17-19.
M. Sivaprakasam, W. Liu, M. S. Humayun, and J. D. Weiland   A Variable Range Bi-Phasic Current Stimulus Driver Circuitry for an Implantable Retinal Prosthetic Device, IEEE Journal of Solid-State Circuit, 2005; 40: 763 – 771.
M. Yuce, W. Liu   A low power multirate DPSK receiver for space applications, IEEE Transactions on Vehicular Technology, 2005; 54(2074-2084): .
G. A. Kendir, W. Liu, G. Wang, M. Sivaprakasam, R. Bashirullah, M. S. Humayun, and J. D. Weiland   An Optimal Design Methodology for Inductive Power Link with Class-E Amplifier, IEEE Transactions on Circuits and Systems – I, 2005; 52: 857 – 866.
M. Sivaprakasam, W. Liu, G. Wang, J. D. Weiland, and M. S. Humayun   Architecture Tradeoffs in High Density Microstimulators for Retinal Prosthesis, IEEE Transactions on Circuits and Systems – I, Special Issue on Biomedical Circuits and Systems, 2005; 52: 2629-2641.
M. Sivaprakasam, W. Liu, G. Wang, J. D. Weiland, and M. S. Humayun   Architecture Tradeoffs in High Density Microstimulators for Retinal Prosthesis, IEEE Transactions on Circuits and Systems – I, Special Issue on Biomedical Circuits and Systems, 2005; 52: 2629-2641.
G. Wang, W. Liu, M. Sivaprakasam, and G. A. Kendir   Design and Analysis of an Adaptive Transcutaneous Power Telemetry for Biomedical Implants, IEEE Transactions on Circuits and Systems – I, 2005; 52: 857-866.
W. Liu, M. Sivaprakasam, G. Wang, M. Zhou, J. Granacki, J. LaCoss, J. Wills   Microelectronics Design for Implantable Wireless Biomimetic Microelectronic Systems, IEEE Engineering in Medicine and Biology Magazine, 2005; 24: 66 – 74.
J. D. Weiland, W. Liu and M. Humayun   Retinal Prosthesis, Annual Review of Biomedical Engineering, 2005; 7: .
R. Bashirullah, W. Liu, R. Cavin, and D. Edwards   “A Hybrid Current/Voltage Mode On-Chip Signaling Scheme With Adaptive Bandwidth Capability, IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2004; 12: 876-880.
S. DeMarco, W. Liu, P. R. Singh, G. Lazzi, M. Humayun, J. Weiland   An Arbitrary Waveform Stimulus Circuit for Visual Prostheses using a Low Area Multibias DAC, IEEE Journal of Solid State Circuits, 2003; .
S. C. Demarco, G. Lazzi, W. Liu, J. D. Weiland, and M. S. Humayun   Computed SAR and Thermal Elevation in a 0.25-mm 2-D Model of the Human Eye and Head in Response to an Implanted Retinal Stimulator – Part I: Models and Methods, IEEE Transactions on Antennas and Propagation, 2003; 51: 2274-2285.
S. C. Demarco, G. Lazzi, W. Liu, J. D. Weiland, and M. S. Humayun,   Computed SAR and Thermal Elevation in a 0.25-mm 2-D Model of the Human Eye and Head in Response to an Implanted Retinal Stimulator – Part II: Models and Methods, IEEE Transactions on Antennas and Propagation, 2003; 51: 2286-2295.
R. Bashirullah, W. Liu, and R. Cavin III   Current-Mode Signaling in Deep Submicron Global Interconnects, IEEE Transactions on Very Large Scale Integration (VLSI) Systems, 2003; 11: 406-417.
W. Liu, M. Sivaprakasam, P. R. Singh, R. Bashirullah, and G. Wang   Electronic Visual Prostheses, Artificial Organs, 2003; 27: 986-995.
R. Bashirullah, W. Liu   Raised Cosine Approximation Signaling for Reduced Noise Cross-talk, IEEE Electronic Letters, 2002; 38(21): 1256-1258.
E. Margalit, M. Maia, J. Weiland, R. Greenberg, G. Fujii , G. Torres, D. Piyathaisere, T. O’Hearn, W. Liu, G. Lazzi, G. Dagnelie, D. Scribner, E. de Juan Jr, M. Humayun   Retinal Prosthesis for the Blind, Survey of Opthalmology, 2002; 47(4): 335-356.

Edythe London, Ph.D.

Biography

Dr. London received her Ph.D. in Pharmacology from the University of Maryland and her postdoctoral training at Johns Hopkins School of Medicine. Before coming to UCLA in 2001, she was the Director of the Brain Imaging Center for the National Institute on Drug Abuse, and held faculty appointments at the University of Maryland and Johns Hopkins Schools of Medicine. Dr. London is a Professor-in-Residence in the Departments of Psychiatry and Biobehavioral Sciences and Molecular and Medical Pharmacology. Her work focuses on the use of neuroimaging to study neural circuitry underlying self-control and behaviors related to addiction.

Publications

A selected list of publications:

Lee, B, Groman, S, London, E D, Jentsch, J D   Dopamine D2/D3 receptors play a specific role in the reversal of a learned visual discrimination in monkeys, Neuropsychopharmacology, 2007; 32(10): 2125-2134.
Wong, D F, Kuwabara, H, Schretlen, D J, Bonson, K R, Nandi, A, Brasic, J R, Kimes, A S, Maris, M A, Kumar, A, Contoreggi, C, Links, J, Ernst, M, Rousset, O, Zukin, S, Grace, A A, Lee, J S, Rohde, C, Jasinski, D R, Gjedde, A, London, E D   Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving, Neuropsychopharmacology, 2006; 31(12): 2716-2727.
London, E D, Berman, S M, Voytek, B, Simon, S L, Mandelkern, M A, Monterosso, J, Thompson, P M, Brody, A L, Geaga, J A, Hong, M S, Hayashi, K M, Rawson, R A, Ling, W   Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers, Biological Psychiatry, 2005; 58(10): 770-778.
Rotheram-Fuller, E, Shoptaw, S, Berman, S M, London, E D   Impaired performance in a test of decision-making by opiate-dependent tobacco smokers, Drug and Alcohol Dependence, 2004; 73(1): 79-86.
London, E D, Simon, S L, Berman, S M, Mandelkern, M A, Lichtman, A M, Bramen, J, … Ling, W   Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers, Archives of General Psychiatry, 2004; 61(1): 73-84.
Thompson, P M, Hayashi, K M, Simon, S L, Geaga, J A, Hong, M S, Sui, Y, Lee, J Y, Toga, A W, Ling, W, London, E D   Structural abnormalities in the brains of human subjects who use methamphetamine, Journal of Neuroscience, 2004; 24(26): 6028-6036.
Ernst, M, Bolla, K, Mouratidis, M, Contoreggi, C, Matochik, J A, Kurian, V, … London, E D   Decision-making in a risk-taking task: a PET study, Neuropsychopharmacology, 2002; 26(5): 682-691.
Bonson, K R, Grant, S J, Contoreggi C S, Links, J M, Metcalfe J, Weyl, H L, … London, E D   Neural systems and cue-induced cocaine craving, Neuropsychopharmacology, 2002; 26(3): 376-386.
Ernst, M, Heishman, S J, Spurgeon, L, & London, E D   Smoking history and nicotine effects on cognitive performance, Neuropsychopharmacology, 2001; 25(3): 313-319.
Faulkner, P, Ghahremani, D G, Tyndale, R F, Cox, C M, Kazanjian, A S, Paterson, N, Lotfipour, S, Hellemann, G S, Petersen, N, Vigil, C, London, E D   Reduced-Nicotine Cigarettes in Young Smokers: Impact of Nicotine Metabolism on Nicotine Dose Effects Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2017; 42(8): 1610-1618.
Okita, K, Mandelkern, M A, London, E D   Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence The international journal of neuropsychopharmacology, 2016; 19(11): 15-22.
Okita, K, Petersen, N, Robertson, C L, Dean, A C, Mandelkern, M A, London, E D   Sex Differences in Midbrain Dopamine D2-Type Receptor Availability and Association with Nicotine Dependence Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016; 41(12): 2913-2919.
Robertson, C L, Ishibashi, K, Chudzynski, J, Mooney, L J, Rawson, R A, Dolezal, B A, Cooper, C B, Brown, A K, Mandelkern, M A, London, E D   Effect of Exercise Training on Striatal Dopamine D2/D3 Receptors in Methamphetamine Users during Behavioral Treatment Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016; 41(6): 1629-36.
Morales, A M, Kohno, M, Robertson, C L, Dean, A C, Mandelkern, M A, London, E D   Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users Molecular psychiatry, 2015; 20(6): 764-71.
Robertson, C L, Ishibashi, K, Mandelkern, M A, Brown, A K, Ghahremani, D G, Sabb, F, Bilder, R, Cannon, T, Borg, J, London, E D   Striatal D1- and D2-type dopamine receptors are linked to motor response inhibition in human subjects The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015; 35(15): 5990-7.
Kohno, M, Ghahremani, D G, Morales, A M, Robertson, C L, Ishibashi, K, Morgan, A T, Mandelkern, M A, London, E D   Risk-taking behavior: dopamine D2/D3 receptors, feedback, and frontolimbic activity Cerebral cortex (New York, N.Y. : 1991), 2015; 25(1): 236-45.
O’Neill, J, Tobias, M C, Hudkins, M, London, E D   Glutamatergic neurometabolites during early abstinence from chronic methamphetamine abuse The international journal of neuropsychopharmacology, 2014; 18(3): 236-45.
Kohno, M, Morales, A M, Ghahremani, D G, Hellemann, G, London, E D   Risky decision making, prefrontal cortex, and mesocorticolimbic functional connectivity in methamphetamine dependence JAMA psychiatry, 2014; 71(7): 812-20.
O’Neill, J, Tobias, M C, Hudkins, M, Oh, E Y, Hellemann, G S, Nurmi, E L, London, E D   Thalamic glutamate decreases with cigarette smoking Psychopharmacology, 2014; 231(13): 2717-24.
Groman, S M, Morales, A M, Lee, B, London, E D, Jentsch, J D   Methamphetamine-induced increases in putamen gray matter associate with inhibitory control Psychopharmacology, 2013; 229(3): 527-38.
Brown, A K, Mandelkern, M A, Farahi, J, Robertson, C, Ghahremani, D G, Sumerel, B, Moallem, N, London, E D   Sex differences in striatal dopamine D2/D3 receptor availability in smokers and non-smokers The international journal of neuropsychopharmacology, 2012; 15(7): 989-94.
Zorick, T, Lee, B, Mandelkern, M A, Fong, T, Robertson, C, Ghahremani, D G, Brown, A K, Sumerel, B, London, E D   Low striatal dopamine receptor availability linked to caloric intake during abstinence from chronic methamphetamine abuse Molecular psychiatry, 2012; 17(6): 569-71.
Ghahremani, D G, Lee, B, Robertson, C L, Tabibnia, G, Morgan, A T, De Shetler, N, Brown, A K, Monterosso, J R, Aron, A R, Mandelkern, M A, Poldrack, R A, London, E D   Striatal dopamine D₂/D₃ receptors mediate response inhibition and related activity in frontostriatal neural circuitry in humans The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012; 32(21): 7316-24.
Ishibashi, K, Berman, S M, Paz-Filho, G, Lee, B, Robertson, C, Mandelkern, M A, Wong, M L, Licinio, J, London, E D   Dopamine D2/D3 receptor availability in genetically leptin-deficient patients after long-term leptin replacement Molecular psychiatry, 2012; 17(4): 352-3.
Groman, S M, Lee, B, Seu, E, James, A S, Feiler, K, Mandelkern, M A, London, E D, Jentsch, J D   Dysregulation of D₂-mediated dopamine transmission in monkeys after chronic escalating methamphetamine exposure The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012; 32(17): 5843-52.
Payer, D E, Nurmi, E L, Wilson, S A, McCracken, J T, London, E D   Effects of methamphetamine abuse and serotonin transporter gene variants on aggression and emotion-processing neurocircuitry Translational psychiatry, 2012; 2(4): e80.
Dean, A C, Sevak, R J, Monterosso, J R, Hellemann, G, Sugar, C A, London, E D   Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans Journal of studies on alcohol and drugs, 2011; 72(6): 943-53.
Zorick, T, Sugar, C A, Hellemann, G, Shoptaw, S, London, E D   Poor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamine Drug and alcohol dependence, 2011; 118(2-3): 500-3.
Ghahremani, D G, Tabibnia, G, Monterosso, J, Hellemann, G, Poldrack, R A, London, E D   Effect of modafinil on learning and task-related brain activity in methamphetamine-dependent and healthy individuals Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011; 36(5): 950-9.
Zorick, T, Mandelkern, M A, Lee, B, Wong, M-L, Miotto, K, Shabazian, J, London, E D   Elevated plasma prolactin in abstinent methamphetamine-dependent subjects The American journal of drug and alcohol abuse, 2011; 37(1): 62-7.
Zorick, T, Sevak, R J, Miotto, K, Shoptaw, S, Swanson, A-N, Clement, C, De La Garza, R, Newton, T F, London, E D   Pilot safety evaluation of varenicline for the treatment of methamphetamine dependence Journal of experimental pharmacology, 2010; 2(10): 13-8.
Zorick, T, Nestor, L, Miotto, K, Sugar, C, Hellemann, G, Scanlon, G, Rawson, R, London, E D   Withdrawal symptoms in abstinent methamphetamine-dependent subjects Addiction (Abingdon, England), 2010; 105(10): 1809-18.
Azizian, A, Nestor, L J, Payer, D, Monterosso, J R, Brody, A L, London, E D   Smoking reduces conflict-related anterior cingulate activity in abstinent cigarette smokers performing a Stroop task Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010; 35(3): 775-82.
London, E D, Berman, S M, Mohammadian, P, Ritchie, T, Mandelkern, M A, Susselman, M K W, Schlagenhauf, F, Noble, E P   Effect of the TaqIA polymorphism on ethanol response in the brain Psychiatry research, 2009; 174(3): 163-70.
Lee, B, London, E D, Poldrack, R A, Farahi, J, Nacca, A, Monterosso, J R, Mumford, J A, Bokarius, A V, Dahlbom, M, Mukherjee, J, Bilder, R M, Brody, A L, Mandelkern, M A   Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(47): 14734-40.
Brody, A L, Mandelkern, M A, Olmstead, R E, Allen-Martinez, Z, Scheibal, D, Abrams, A L, Costello, M R, Farahi, J, Saxena, S, Monterosso, J, London, E D   Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigarette Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009; 34(2): 282-9.
Xu, J, Azizian, A, Monterosso, J, Domier, C P, Brody, A L, Fong, T W, London, E D   Gender effects on mood and cigarette craving during early abstinence and resumption of smoking Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008; 10(11): 1653-61.
Berman, S M, Voytek, B, Mandelkern, M A, Hassid, B D, Isaacson, A, Monterosso, J, Miotto, K, Ling, W, London, E D   Changes in cerebral glucose metabolism during early abstinence from chronic methamphetamine abuse Molecular psychiatry, 2008; 13(9): 897-908.
Baicy, K, London, E D, Monterosso, J, Wong, M-L, Delibasi, T, Sharma, A, Licinio, J   Leptin replacement alters brain response to food cues in genetically leptin-deficient adults Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(46): 18276-9.
Galynker, I I, Eisenberg, D, Matochik, J A, Gertmenian-King, E, Cohen, L, Kimes, A S, Contoreggi, C, Kurian, V, Ernst, M, Rosenthal, R N, Prosser, J, London, E D   Cerebral metabolism and mood in remitted opiate dependence Drug and alcohol dependence, 2007; 90(2-3): 166-74.
Xu, J, Mendrek, A, Cohen, M S, Monterosso, J, Simon, S, Brody, A L, Jarvik, M, Rodriguez, P, Ernst, M, London, E D   Effects of acute smoking on brain activity vary with abstinence in smokers performing the N-Back task: a preliminary study Psychiatry research, 2006; 148(2-3): 103-9.
Ernst M, Matochik J A, Heishman S J, Van Horn J D, Jons P H, Henningfield J E, London E D   Effect of nicotine on brain activation during performance of a working memory task Proceedings of the National Academy of Sciences of the United States of America, 2001; 98(8): 4728-33.
Mukhin A G, Gündisch D, Horti A G, Koren A O, Tamagnan G, Kimes A S, Chambers J, Vaupel D B, King S L, Picciotto M R, Innis R B, London E D   5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors Molecular pharmacology, 2000; 57(3): 642-9.
1 2 3 5