Biography
The role of TRH in anti-depressant treatment The roles of TRH and related peptides in the pathophysiology and treatment of major mental disorders.
Biography
Steve Shoptaw is a licensed psychologist and Professor in the UCLA Departments of Family Medicine and Psychiatry and Biobehavioral Sciences. Dr. Shoptaw joined the Department of Family Medicine as full professor in 2005. Prior to this, Dr. Shoptaw was a Research Psychologist with the Integrated Substance Abuse Program in the Dept. of Psychiatry & Behavioral Science since 2003. Dr. Shoptaw earned his BA (1982) in Psychology and MA (1985) and Ph.D. (1990) in Psychology at UCLA. His dissertation was nominated for the Gingerelli Award for Excellence in the Department of Psychology. Dr. Shoptaw completed his postdoctoral training in Psychophysiology at the UCLA NPI/VAMC in Sepulveda, CA in 1991. Following that, Dr. Shoptaw worked for 10 years as a Principal Investigator with Friends Research Institute, Inc., during which time, his program of clinical research with substance abusers supported opening several treatment research clinics in Rancho Cucamonga, Hollywood, South Los Angeles, and West Hollywood. Dr. Shoptaw received the FRI Daniel Mendelsohn Young Investigator Award in 1996 and a mentoring award in 2000. In 1996, Dr. Shoptaw opened Safe House, a 24 bed facility that provides emergency, transitional and permanent housing to persons living with HIV/AIDS, chemical dependency, transitional and permanent housing to persons living with HIV/AIDS, chemical dependency, and mental illness who are homeless or at risk for homelessness. He continues with this program as a volunteer Executive Director. These linkages of clinical research and community collaboration have led Dr. Shoptaw???s work to influence practice guidelines in intervening with substance abusers, especially those at high risk for HIV transmission, locally, nationally and in emerging international epidemics.
Publications
A selected list of publications:
Ling Murtaugh Kimberly, Krishnamurti Tamar, Davis Alexander L, Reback Cathy J, Shoptaw Steven Spend today, clean tomorrow: Predicting methamphetamine abstinence in a randomized controlled trial Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2013; 32(9): 958-66.
Koblin Beryl A, Mayer Kenneth H, Eshleman Susan H, Wang Lei, Mannheimer Sharon, Del Rio Carlos, Shoptaw Steven, Magnus Manya, Buchbinder Susan, Wilton Leo, Liu Ting-Yuan, Cummings Vanessa, Piwowar-Manning Estelle, Fields Sheldon D, Griffith Sam, Elharrar Vanessa, Wheeler Darrell, Wheeler Darrell Correlates of HIV Acquisition in a Cohort of Black Men Who Have Sex with Men in the United States: HIV Prevention Trials Network (HPTN) 061 PloS one, 2013; 8(7): e70413.
Landovitz Raphael J, Tseng Chi-Hong, Weissman Matthew, Haymer Michael, Mendenhall Brett, Rogers Kathryn, Veniegas Rosemary, Gorbach Pamina M, Reback Cathy J, Shoptaw Steven Epidemiology, Sexual Risk Behavior, and HIV Prevention Practices of Men who Have Sex with Men Using GRINDR in Los Angeles, California Journal of urban health : bulletin of the New York Academy of Medicine, 2013; 90(4): 729-39.
Reback Cathy J, Fletcher Jesse B, Shoptaw Steven, Grella Christine E Methamphetamine and other substance use trends among street-recruited men who have sex with men, from 2008 to 2011 Drug and alcohol dependence, 2013; 8(7): .
Swanson Aimee-Noelle, Shoptaw Steven, Heinzerling Keith Gregory, Wade Adam C, Worley Matthew, McCracken James, Wilson Sarah A, Asarnow Joan, London Edythe D Up in Smoke? A Preliminary Open-Label Trial of Nicotine Replacement Therapy and Cognitive Behavioral Motivational Enhancement for Smoking Cessation Among Youth in Los Angeles Substance use & misuse, 2013; 8(7): .
Murphy Ryan D, Gorbach Pamina M, Weiss Robert E, Hucks-Ortiz Christopher, Shoptaw Steven J Seroadaptation in a sample of very poor Los Angeles area men who have sex with men AIDS and behavior, 2013; 17(5): 1862-72.
Herrick Amy L, Stall Ron, Chmiel Joan S, Guadamuz Thomas E, Penniman Typhanye, Shoptaw Steven, Ostrow David, Plankey Michael W It gets better: resolution of internalized homophobia over time and associations with positive health outcomes among MSM AIDS and behavior, 2013; 17(4): 1423-30.
Ding Yingying, He Na, Shoptaw Steven, Gao Meiyang, Detels Roger Severity of club drug dependence and perceived need for treatment among a sample of adult club drug users in Shanghai, China Social psychiatry and psychiatric epidemiology, 2013; 17(5): .
Brensilver Matthew, Heinzerling Keith G, Shoptaw Steven Pharmacotherapy of amphetamine-type stimulant dependence: An update Drug and alcohol review, 2013; 17(4): .
Heinzerling Keith G, Gadzhyan Janette, van Oudheusden Henry, Rodriguez Felipe, McCracken James, Shoptaw Steven Pilot randomized trial of bupropion for adolescent methamphetamine abuse/dependence The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2013; 52(4): 502-5.
Herrick Amy L, Lim Sin How, Plankey Michael W, Chmiel Joan S, Guadamuz Thomas E, Guadamuz Thomas T, Kao Uyen, Shoptaw Steven, Carrico Adam, Ostrow David, Stall Ron Adversity and syndemic production among men participating in the multicenter AIDS cohort study: a life-course approach American journal of public health, 2013; 103(1): 79-85.
Nyamathi Adeline, Salem Benissa, Reback Cathy J, Shoptaw Steven, Branson Catherine M, Idemundia Faith E, Kennedy Barbara, Khalilifard Farinaz, Marfisee Mary, Liu Yihang Correlates of hepatitis B virus and HIV knowledge among gay and bisexual homeless young adults in Hollywood American journal of men’s health, 2013; 7(1): 18-26.
Reback Cathy J, Grant Deborah Ling, Fletcher Jesse B, Branson Catherine M, Shoptaw Steven, Bowers Jane Rohde, Charania Mahnaz, Mansergh Gordon Erratum to: Text Messaging Reduces HIV Risk Behaviors Among Methamphetamine-Using Men Who Have Sex with Men AIDS and behavior, 2012; .
Strathdee Steffanie A, Shoptaw Steven, Dyer Typhanye Penniman, Quan Vu Minh, Aramrattana Apinun, Aramrattana Apinun Towards combination HIV prevention for injection drug users: addressing addictophobia, apathy and inattention Current opinion in HIV and AIDS, 2012; 7(4): 320-325.
Landovitz Raphael J, Fletcher Jesse B, Inzhakova Galina, Lake Jordan E, Shoptaw Steven, Reback Cathy J A Novel Combination HIV Prevention Strategy: Post-Exposure Prophylaxis with Contingency Management for Substance Abuse Treatment Among Methamphetamine-Using Men Who Have Sex with Men AIDS patient care and STDs, 2012; 26(6): 320-8.
Reback Cathy J, Grant Deborah Ling, Fletcher Jesse B, Branson Catherine M, Shoptaw Steven, Bowers Jane Rohde, Charania Mahnaz, Mansergh Gordon Text Messaging Reduces HIV Risk Behaviors Among Methamphetamine-Using Men Who Have Sex with Men AIDS and behavior, 2012; 26(6): .
Brensilver Matthew, Heinzerling Keith G, Swanson Aimee-Noelle, Shoptaw Steven J A retrospective analysis of two randomized trials of bupropion for methamphetamine dependence: Suggested guidelines for treatment discontinuation/augmentation Drug and alcohol dependence, 2012; 26(6): .
Heinzerling Keith G, Shoptaw Steven Gender, brain-derived neurotrophic factor Val66Met, and frequency of methamphetamine use Gender medicine, 2012; 9(2): 112-20.
Brensilver Matthew, Heinzerling Keith G, Swanson Aimee-Noelle, Telesca Donatello, Furst Benjamin A, Shoptaw Steven J Cigarette smoking as a target for potentiating outcomes for methamphetamine abuse treatment Drug and alcohol review, 2012; 9(2): .
Heinzerling Keith G, McCracken James T, Swanson Aimee-Noelle, Ray Lara A, Shoptaw Steven J COMT Val158Met, BDNF Val66Met, and OPRM1 Asn40Asp and methamphetamine dependence treatment response: preliminary investigation Journal of clinical psychopharmacology, 2012; 32(1): 135-7.
Ling Walter, Shoptaw Steven, Hillhouse Maureen, Bholat Michelle A, Charuvastra Charles, Heinzerling Keith, Chim David, Annon Jeffrey, Dowling Patrick T, Doraimani Geetha Double-blind placebo-controlled evaluation of the PROMETA⢠protocol for methamphetamine dependence Addiction (Abingdon, England), 2012; 107(2): 361-9.
Reback Cathy J, Shoptaw Steven Development of an evidence-based, gay-specific cognitive behavioral therapy intervention for methamphetamine-abusing gay and bisexual men Addictive behaviors, 2011; 32(1): .
Xu Hongquan, Shen Qing, Yang Xiaowei, Shoptaw Steven A quasi F-test for functional linear models with functional covariates and its application to longitudinal data Statistics in medicine, 2011; 30(23): 2842-53.
Ober Allison J, Iguchi Martin Y, Weiss Robert E, Gorbach Pamina M, Heimer Robert, Ouellet Lawrence J, Shoptaw Steven, Anglin M Douglas, Zule William A The relative role of perceived partner risks in promoting condom use in a three-city sample of high-risk, low-income women AIDS and behavior, 2011; 15(7): 1347-58.
Tross Susan, Campbell Aimee N C, Calsyn Donald A, Metsch Lisa R, Sorensen James L, Shoptaw Steven, Haynes Louise, Woody George E, Malow Robert M, Brown Lawrence S, Feaster Daniel J, Booth Robert E, Mandler Raul N, Masson Carmen, Holmes Beverly W, Colfax Grant, Brooks Audrey J, Hien Denise A, Schackman Bruce R, Korthuis P Todd, Miele Gloria M, Miele Gloria M NIDA’s Clinical Trials Network: an opportunity for HIV research in community substance abuse treatment programs The American journal of drug and alcohol abuse, 2011; 37(5): 283-93.
Young Sean D, Shoptaw Steven, Weiss Robert E, Munjas Brett, Gorbach Pamina M Predictors of unrecognized HIV infection among poor and ethnic men who have sex with men in Los Angeles AIDS and behavior, 2011; 15(3): 643-9.
Biography
Steroid synthesis and action in the vertebrate CNS. My laboratory is interested in the hormonal control of brain and behavior. Steroid hormones influence the CNS in diverse ways, from regulating neuronal transcription, to influencing cell signaling pathways, to direct modulation of neurotransmitter receptor ion channels. The traditional view is that neurally active steroids come from the gonads and adrenals, but we and others have evidence that in some cases, steroids can be synthesized directly in the brain. We are testing this hypothesis in songbirds that have a variety of well-characterized endpoints of steroid action on brain including organizing neural circuits developmentally, activating circuits and stimulating persistent neural plasticity in adults. We utilize molecular, biochemical and neuroanatomical approaches to explore the expression, activity and function of steroid synthetic enzymes. In addition, we do field research on birds, including one called the Golden-collared manakin that lives in the rainforests of Panama. Males of this species have a remarkable, acrobatic and noisy courtship display. We study how hormones act on the brain, spinal cord and peripheral muscles to give males the ability to perform these elaborate displays.
Publications
A selected list of publications:
Pradhan Devaleena S, Newman Amy E M, Wacker Douglas W, Wingfield John C, Schlinger Barney A, Soma Kiran K Aggressive interactions rapidly increase androgen synthesis in the brain during the non-breeding season Hormones and behavior, 2010; 57(4-5): 381-9.
Feng Ni Y, Katz Amnon, Day Lainy B, Barske Julia, Schlinger Barney A Limb muscles are androgen targets in an acrobatic tropical bird Endocrinology, 2010; 151(3): 1042-9.
Remage-Healey Luke, Coleman Melissa J, Oyama Randi K, Schlinger Barney A Brain estrogens rapidly strengthen auditory encoding and guide song preference in a songbird Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(8): 3852-7.
London Sarah E, Remage-Healey Luke, Schlinger Barney A Neurosteroid production in the songbird brain: a re-evaluation of core principles Frontiers in neuroendocrinology, 2009; 30(3): 302-14.
Salwiczek Lucie H, Emery Nathan J, Schlinger Barney, Clayton Nicola S The development of caching and object permanence in Western scrub-jays (Aphelocoma californica): which emerges first? Journal of comparative psychology (Washington, D.C. : 1983), 2009; 123(3): 295-303.
Remage-Healey Luke, Maidment Nigel T, Schlinger Barney A Forebrain steroid levels fluctuate rapidly during social interactions Nature neuroscience, 2008; 11(11): 1327-34.
Schlinger Barney A, Day Lainy B, Fusani Leonida Behavior, natural history and neuroendocrinology of a tropical bird General and comparative endocrinology, 2008; 157(3): 254-8.
Katz Amnon, Mirzatoni Anahid, Zhen Yin, Schlinger Barney A Sex differences in cell proliferation and glucocorticoid responsiveness in the zebra finch brain The European journal of neuroscience, 2008; 28(1): 99-106.
London Sarah E, Monks D Ashley, Wade Juli, Schlinger Barney A Widespread capacity for steroid synthesis in the avian brain and song system Endocrinology, 2006; 147(12): 5975-87.