Biography
Molecular and cellular analysis of nervous system regeneration Dr. Lévesque is internationally known for his work in the microsurgery of epilepsy and functional stereotactic neurosurgery. He developed a stereotactic imaging system for targeting and operating within precise landmarks to preserve eloquent cortex and a unique technique of selective hippocampectomy by posterior transinsular approach. Dr. Lévesque has now expanded the application of new methods of brain mapping to treat children with autistic-like features, with Landau-Kleffner syndrome, as well as for patients with severe infantile spasms. Dr. Lévesque, who has more than 100 publications in this field, is a consultant to the NIH and to the national and state medical committees.
Publications
A selected list of publications:
Lasky Joseph L, Panosyan Eduard H, Plant Ashley, Davidson Tom, Yong William H, Prins Robert M, Liau Linda M, Moore Theodore B Autologous tumor lysate-pulsed dendritic cell immunotherapy for pediatric patients with newly diagnosed or recurrent high-grade gliomas Anticancer research, 2013; 33(5): 2047-56.
Panosyan Eduard H, Ikeda Alan K, Chang Vivian Y, Laks Dan R, Reeb Charles L, Bowles La Vette, Lasky Joseph L, Moore Theodore B High-dose chemotherapy with autologous hematopoietic stem-cell rescue for pediatric brain tumor patients: a single institution experience from UCLA Journal of transplantation, 2011; 2011(5): 740673.
Lasky Joseph L, Choe Meeryo, Nakano Ichiro Cancer stem cells in pediatric brain tumors Current stem cell research & therapy, 2009; 4(4): 298-305.
Mehta Rupal I, Cutler Aaron R, Lasky Joseph L, Yong William H, Lerner Jason T, Hirota Brandon K, Salamon Noriko, Mathern Gary W, Vinters Harry V “Primary” leptomeningeal medulloblastoma Human pathology, 2009; 40(11): 1661-5.
Guo Wei, Lasky Joseph L, Chang Chun-Ju, Mosessian Sherly, Lewis Xiaoman, Xiao Yun, Yeh Jennifer E, Chen James Y, Iruela-Arispe M Luisa, Varella-Garcia Marileila, Wu Hong Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation Nature, 2008; 453(7194): 529-33.
Ela-Dalman Noa, Arnold Anthony C, Chang Louis K, Velez Federico G, Lasky Joseph L Abducens nerve ocular neuromyotonia following non-sellar or parasellar tumors Strabismus, 2008; 15(3): 149-51.
Lasky Joseph L, Choi Eun Jun, Johnston Samantha, Yong William H, Lazareff Jorge, Moore Theodore Congenital brain tumors: case series and review of the literature Journal of pediatric hematology/oncology, 2008; 30(4): 326-31.
Lasky Joseph L, Liau Linda M Targeting stem cells in brain tumors Technology in cancer research & treatment, 2006; 5(3): 251-60.
Luu Quang C, Lasky Joseph L, Moore Theodore B, Nelson Scott, Wang Marilene B Treatment of embryonal rhabdomyosarcoma of the sinus and orbit with chemotherapy, radiation, and endoscopic surgery Journal of pediatric surgery, 2006; 41(6): e15-7.
Guo Wei, Lasky Joseph L, Wu Hong Cancer stem cells Pediatric research, 2006; 59(4 Pt 2): 59R-64R.
Biography
Dr. Mathern graduated from the Case Western Reserve University School of Medicine in 1982. He completed his Rotating Internship at the Cleveland Clinic Foundation in 1983 and his Residencies in Surgery (1985) and Neurosurgery (1986-1991) at UCLA Harbor Medical Center and UCLA School of Medicine, respectively. Dr. Mathern received his Board Certification in Neurological Surgery in 1996. He currently practices medicine at the David Geffen UCLA School of Medicine and specializes in Neurological Surgery and Pediatric Neurological Surgery. Dr. Mathern is affiliated with both Santa Monica UCLA Medical Center and Ronald Reagan UCLA Medical Center.