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Steven Clarke, Ph.D.

Biography

Steven Clarke has been on the faculty of the UCLA Department of Chemistry and Biochemistry since 1978. He is currently a Distinguished Professor of Biochemistry and Director of the UCLA Cellular and Molecular Biology Training Program. He was born in Los Angeles and attended public schools in Altadena and Pasadena, California. He did his undergraduate work at Pomona College in Claremont, majoring in Chemistry and Zoology. During this time, he did undergraduate research at the UCLA Brain Research Institute with Dr. James E. Skinner and Professor Donald Lindsley on neural mechanisms of attention. He was also an NIH fellow in the laboratory of Dr. Peter Mitchell at Glynn Research Laboratories in Bodmin, England studying mitochondrial amino acid transport. He obtained his PhD in Biochemistry and Molecular Biology at Harvard University working as an NSF Fellow with Professor Guido Guidotti on membrane protein-detergent interactions and the identification of the major rat liver mitochondrial polypeptides as enzymes of the urea cycle. He returned to California to do postdoctoral work as a Miller Fellow at the University of California, Berkeley, with Professor Dan Koshland, identifying membrane receptors for bacterial chemotaxis. His research at UCLA has focused on roles of novel protein methyltransferases in aging and biological regulation highlighted by discoveries of the protein L-isoaspartyl repair methyltransferase, the isoprenylcysteine protein methyltransferase, and the protein phosphatase 2A methyltransferase. He has been a visiting scholar at Princeton University (1986-87), the University of Washington (2004-2005), and Vanderbilt University (2015).

Publications

A selected list of publications:

Warmack Rebeccah A, Mansilla Eduardo, Goya Rodolfo G, Clarke Steven G   Racemized and Isomerized Proteins in Aging Rat Teeth and Eye Lens Rejuvenation research, 2016; 19(4): 309-17.
Jain Kanishk, Warmack Rebeccah A, Debler Erik W, Hadjikyriacou Andrea, Stavropoulos Peter, Clarke Steven G   Protein Arginine Methyltransferase Product Specificity is Mediated by Distinct Active-Site Architectures The Journal of biological chemistry, 2016; .
Lowenson Jonathan D, Shmanai Vadim V, Shklyaruck Denis, Clarke Steven G, Shchepinov Mikhail S   Deuteration protects asparagine residues against racemization Amino acids, 2016; 19(4): .
Sherkhanov Saken, Korman Tyler P, Clarke Steven G, Bowie James U   Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme Scientific reports, 2016; 6(4): 24239.
Al-Hadid Qais, Roy Kevin, Chanfreau Guillaume, Clarke Steven G   Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity RNA (New York, N.Y.), 2016; 22(4): 489-98.
Debler Erik W, Jain Kanishk, Warmack Rebeccah A, Feng You, Clarke Steven G, Blobel Günter, Stavropoulos Pete   A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(8): 2068-73.
Al-Hadid Qais, White Jonelle, Clarke Steven   Ribosomal protein methyltransferases in the yeast Saccharomyces cerevisiae: Roles in ribosome biogenesis and translation Biochemical and biophysical research communications, 2016; 470(3): 552-7.
Fu Xudong, Chin Randall M, Vergnes Laurent, Hwang Heejun, Deng Gang, Xing Yanpeng, Pai Melody Y, Li Sichen, Ta Lisa, Fazlollahi Farbod, Chen Chuo, Prins Robert M, Teitell Michael A, Nathanson David A, Lai Albert, Faull Kym F, Jiang Meisheng, Clarke Steven G, Cloughesy Timothy F, Graeber Thomas G, Braas Daniel, Christofk Heather R, Jung Michael E, Reue Karen, Huang Jing   2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling Cell metabolism, 2015; 22(3): 508-15.
Yang Yanzhong, Hadjikyriacou Andrea, Xia Zheng, Gayatri Sitaram, Kim Daehoon, Zurita-Lopez Cecilia, Kelly Ryan, Guo Ailan, Li Wei, Clarke Steven G, Bedford Mark T   PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145 Nature communications, 2015; 6(27): 6428.
Hadjikyriacou Andrea, Yang Yanzhong, Espejo Alexsandra, Bedford Mark T, Clarke Steven G   Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2 The Journal of biological chemistry, 2015; 290(27): 16723-43.
Patananan Alexander N, Budenholzer Lauren M, Pedraza Maria E, Torres Eric R, Adler Lital N, Clarke Steven G   The invertebrate Caenorhabditis elegans biosynthesizes ascorbate Archives of biochemistry and biophysics, 2015; 569(27): 32-44.
Patananan Alexander Nikolich, Budenholzer Lauren Michelle, Eskin Ascia, Torres Eric Rommel, Clarke Steven Gerard   Ethanol-induced differential gene expression and acetyl-CoA metabolism in a longevity model of the nematode Caenorhabditis elegans Experimental gerontology, 2015; 61(27): 20-30.
Dzialo Maria C, Travaglini Kyle J, Shen Sean, Loo Joseph A, Clarke Steven G   A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A Biochemical and biophysical research communications, 2014; 455(3-4): 382-9.
Feng You, Hadjikyriacou Andrea, Clarke Steven G   Substrate specificity of human protein arginine methyltransferase 7 (PRMT7): the importance of acidic residues in the double E loop The Journal of biological chemistry, 2014; 289(47): 32604-16.
Dzialo Maria C, Travaglini Kyle J, Shen Sean, Roy Kevin, Chanfreau Guillaume F, Loo Joseph A, Clarke Steven G   Translational roles of elongation factor 2 protein lysine methylation The Journal of biological chemistry, 2014; 289(44): 30511-24.
Al-Hadid Qais, Roy Kevin, Munroe William, Dzialo Maria C, Chanfreau Guillaume F, Clarke Steven G   Histidine methylation of yeast ribosomal protein Rpl3p is required for proper 60S subunit assembly Molecular and cellular biology, 2014; 34(15): 2903-16.
Patananan Alexander N, Capri Joseph, Whitelegge Julian P, Clarke Steven G   Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae The Journal of biological chemistry, 2014; 289(24): 16936-53.
Lissina Elena, Weiss David, Young Brian, Rella Antonella, Cheung-Ong Kahlin, Del Poeta Maurizio, Clarke Steven G, Giaever Guri, Nislow Corey   A novel small molecule methyltransferase is important for virulence in Candida albicans ACS chemical biology, 2013; 8(12): 2785-93.
Feng You, Maity Ranjan, Whitelegge Julian P, Hadjikyriacou Andrea, Li Ziwei, Zurita-Lopez Cecilia, Al-Hadid Qais, Clark Amander T, Bedford Mark T, Masson Jean-Yves, Clarke Steven G   Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions The Journal of biological chemistry, 2013; 288(52): 37010-25.
Yang Hongqian, Lowenson Jonathan D, Clarke Steven, Zubarev Roman A   Brain proteomics supports the role of glutamate metabolism and suggests other metabolic alterations in protein l-isoaspartyl methyltransferase (PIMT)-knockout mice Journal of proteome research, 2013; 12(10): 4566-76.
Shen-Miller J, Lindner Petra, Xie Yongming, Villa Sarah, Wooding Kerry, Clarke Steven G, Loo Rachel R O, Loo Joseph A   Thermal-stable proteins of fruit of long-living Sacred Lotus Nelumbo nucifera Gaertn var. China Antique Tropical plant biology, 2013; 6(2-3): .
Nayak Nihar R, Putnam Andrea A, Addepalli Balasubrahmanyam, Lowenson Jonathan D, Chen Tingsu, Jankowsky Eckhard, Perry Sharyn E, Dinkins Randy D, Limbach Patrick A, Clarke Steven G, Downie A Bruce   An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE The Plant cell, 2013; 25(7): 2573-86.
Patananan Alexander N, Palmer Jonathan M, Garvey Graeme S, Keller Nancy P, Clarke Steven G   A novel automethylation reaction in the Aspergillus nidulans LaeA protein generates S-methylmethionine The Journal of biological chemistry, 2013; 288(20): 14032-45.
Clarke Steven G   Protein methylation at the surface and buried deep: thinking outside the histone box Trends in biochemical sciences, 2013; 38(5): 243-52.
Dai Shujia, Ni Wenqin, Patananan Alexander N, Clarke Steven G, Karger Barry L, Zhou Zhaohui Sunny   Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice Analytical chemistry, 2013; 85(4): 2423-30.
Dhar Surbhi, Vemulapalli Vidyasiri, Patananan Alexander N, Huang Grace L, Di Lorenzo Alessandra, Richard Stephane, Comb Michael J, Guo Ailan, Clarke Steven G, Bedford Mark T   Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs Scientific reports, 2013; 3(1): 1311.
Yang Mei-Ling, Gee Alaric J P, Gee Renelle J, Zurita-Lopez Cecilia I, Khare Shilpi, Clarke Steven G, Mamula Mark J   Lupus autoimmunity altered by cellular methylation metabolism Autoimmunity, 2013; 46(1): 21-31.
Young Brian D, Weiss David I, Zurita-Lopez Cecilia I, Webb Kristofor J, Clarke Steven G, McBride Anne E   Identification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation Biochemistry, 2012; 51(25): 5091-104.
Castro Paola V, Khare Shilpi, Young Brian D, Clarke Steven G   Caenorhabditis elegans battling starvation stress: low levels of ethanol prolong lifespan in L1 larvae PloS one, 2012; 7(1): e29984.
Zurita-Lopez Cecilia I, Sandberg Troy, Kelly Ryan, Clarke Steven G   Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues The Journal of biological chemistry, 2012; 287(11): 7859-70.
MacKay Kennen B, Lowenson Jonathan D, Clarke Steven G   Wortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- mice PloS one, 2012; 7(10): e46719.
Adler Lital N, Gomez Tara A, Clarke Steven G, Linster Carole L   A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals The Journal of biological chemistry, 2011; 286(24): 21511-23.
Webb Kristofor J, Al-Hadid Qais, Zurita-Lopez Cecilia I, Young Brian D, Lipson Rebecca S, Clarke Steven G   The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase The Journal of biological chemistry, 2011; 286(21): 18405-13.
Petrossian Tanya C, Clarke Steven G   Uncovering the human methyltransferasome Molecular & cellular proteomics : MCP, 2011; 10(1): M110.000976.
Webb Kristofor J, Zurita-Lopez Cecilia I, Al-Hadid Qais, Laganowsky Arthur, Young Brian D, Lipson Rebecca S, Souda Puneet, Faull Kym F, Whitelegge Julian P, Clarke Steven G   A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase The Journal of biological chemistry, 2010; 285(48): 37598-606.
Lipson Rebecca S, Webb Kristofor J, Clarke Steven G   Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae Archives of biochemistry and biophysics, 2010; 500(2): 137-43.
Vinci Chris R, Clarke Steven G   Homocysteine methyltransferases Mht1 and Sam4 prevent the accumulation of age-damaged (R,S)-AdoMet in the yeast Saccharomyces cerevisiae The Journal of biological chemistry, 2010; 285(27): 20526-31.
Webb Kristofor J, Lipson Rebecca S, Al-Hadid Qais, Whitelegge Julian P, Clarke Steven G   Identification of protein N-terminal methyltransferases in yeast and humans Biochemistry, 2010; 49(25): 5225-35.
Fisk John C, Zurita-Lopez Cecilia, Sayegh Joyce, Tomasello Danielle L, Clarke Steven G, Read Laurie K   TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei Eukaryotic cell, 2010; 9(6): 866-77.
Vinci Chris R, Clarke Steven G   Yeast, plants, worms, and flies use a methyltransferase to metabolize age-damaged (R,S)-AdoMet, but what do mammals do? Rejuvenation research, 2010; 13(2-3): 362-4.
Petrossian Tanya, Clarke Steven   Bioinformatic Identification of Novel Methyltransferases Epigenomics, 2009; 1(1): 163-175.
Khare Shilpi, Gomez Tara, Linster Carole L, Clarke Steven G   Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans Mechanisms of ageing and development, 2009; 130(10): 670-80.
Lakowski Ted M, Zurita-Lopez Cecilia, Clarke Steven G, Frankel Adam   Approaches to measuring the activities of protein arginine N-methyltransferases Analytical biochemistry, 2009; .
Petrossian, T. C., and Clarke, S. G.   Bioinformatic Identification of Novel Methyltransferases Epigenomics, 2009; 1: 163-175.
Fisk John C, Sayegh Joyce, Zurita-Lopez Cecilia, Menon Sarita, Presnyak Vladimir, Clarke Steven G, Read Laurie K   A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei The Journal of biological chemistry, 2009; 284(17): 11590-600.
Petrossian Laurie K, Clarke Laurie K   Multiple motif scanning to identify methyltransferases from the yeast proteome Molecular & cellular proteomics : MCP, 2009; 284(17): .
Bedford Mark T, Clarke Steven G   Protein arginine methylation in mammals: who, what, and why Molecular cell, 2009; 33(1): 1-13.
Gomez Tara A, Banfield Kelley L, Clarke Steven G   The protein L-isoaspartyl-O-methyltransferase functions in the Caenorhabditis elegans stress response Mechanisms of ageing and development, 2008; 129(12): 752-8.
Linster Carole L, Clarke Steven G   L-Ascorbate biosynthesis in higher plants: the role of VTC2 Trends in plant science, 2008; 13(11): 567-73.
Sayegh Joyce, Clarke Steven G   Hsl7 is a substrate-specific type II protein arginine methyltransferase in yeast Biochem. Biophys. Res. Commun, 2008; 372(4): 811-5.
Banfield Kelley L, Gomez Tara A, Lee Wendy, Clarke Steven, Larsen Pamela L   Protein-repair and hormone-signaling pathways specify dauer and adult longevity and dauer development in Caenorhabditis elegans The journals of gerontology. Series A, Biological sciences and medical sciences, 2008; 63(8): 798-808.
Dumlao Darren S, Hertz Nicholas, Clarke Steven   Secreted 3-isopropylmalate methyl ester signals invasive growth during amino acid starvation in Saccharomyces cerevisiae Biochemistry, 2008; 47(2): 698-709.
Sayegh Joyce, Webb Kristofor, Cheng Donghang, Bedford Mark T, Clarke Steven G   Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain J. Biol. Chem, 2007; 282(50): 36444-53.
Gomez Tara A, Clarke Steven G   Autophagy and insulin/TOR signaling in Caenorhabditis elegans pcm-1 protein repair mutants Autophagy, 2007; 3(4): 357-9.
Linster Carole L, Gomez Tara A, Christensen Kathryn C, Adler Lital N, Young Brian D, Brenner Charles, Clarke Steven G   Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants J. Biol. Chem, 2007; 282(26): 18879-85.
Gomez Tara A, Banfield Kelley L, Trogler Dorothy M, Clarke Steven G   The L-isoaspartyl-O-methyltransferase in Caenorhabditis elegans larval longevity and autophagy Developmental biology, 2007; 303(2): 493-500.
Villa Sarah T, Xu Qilong, Downie A Bruce, Clarke Steven G   Arabidopsis Protein Repair L-Isoaspartyl Methyltransferases: Predominant Activities at Lethal Temperatures Physiologia plantarum, 2006; 128(4): 581-592.
Farrar Christine E, Huang Christine S, Clarke Steven G, Houser Carolyn R   Increased cell proliferation and granule cell number in the dentate gyrus of protein repair-deficient mice The Journal of comparative neurology, 2005; 493(4): 524-37.
Porras-Yakushi Tanya R, Whitelegge Julian P, Miranda Tina Branscombe, Clarke Steven   A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast The Journal of biological chemistry, 2005; 280(41): 34590-8.
Lee Jaeho, Sayegh Joyce, Daniel Jeremy, Clarke Steven, Bedford Mark T   PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family The Journal of biological chemistry, 2005; 280(38): 32890-6.
Miranda Tina Branscombe, Miranda Mark, Frankel Adam, Clarke Steven   PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity The Journal of biological chemistry, 2004; 279(22): 22902-7.
Young Stephen G, Clarke Steven G, Bergoc Martin O, Phillips Mark, Fong Loren G   10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins The Enzymes, 2006; 24(3): 273-301.
Stetler April, Winograd Claudia, Sayegh Joyce, Cheever Anne, Patton Erin, Zhang Xing, Clarke Steven, Ceman Stephanie   Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp Human molecular genetics, 2006; 15(1): 87-96.
Linster Carole L, Adler Lital N, Webb Kristofor, Christensen Kathryn C, Brenner Charles, Clarke Steven G   A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction The Journal of biological chemistry, 2008; 283(27): 18483-92.
Miranda Tina Branscombe, Webb Kristofor J, Edberg Dale D, Reeves Raymond, Clarke Steven   Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a Biochemical and biophysical research communications, 2005; 336(3): 831-5.
Alfaro Joshua F, Gillies Laura A, Sun He G, Dai Shujia, Zang Tianzhu, Klaene Joshua J, Kim Byung Ju, Lowenson Jonathan D, Clarke Steven G, Karger Barry L, Zhou Zhaohui Sunny   Chemo-enzymatic detection of protein isoaspartate using protein isoaspartate methyltransferase and hydrazine trapping Analytical chemistry, 2008; 80(10): 3882-9.
Lipson Rebecca S, Clarke Steven G   S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase The Journal of biological chemistry, 2007; 282(42): 31094-102.
Kafková Lucie, Debler Erik W, Fisk John C, Jain Kanishk, Clarke Steven G, Read Laurie K   The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex The Journal of biological chemistry, 2017; 292(6): 2089-2100.
Pasternack Deborah A, Sayegh Joyce, Clarke Steven, Read Laurie K   Evolutionarily divergent type II protein arginine methyltransferase in Trypanosoma brucei Eukaryotic cell, 2007; 6(9): 1665-81.
Caslavka Zempel Katelyn E, Vashisht Ajay A, Barshop William D, Wohlschlegel James A, Clarke Steven G   Determining the Mitochondrial Methyl Proteome in Saccharomyces cerevisiae using Heavy Methyl SILAC Journal of proteome research, 2016; 15(12): 4436-4451.
Clarke Steven Gerard   HIV protease inhibitors and nuclear lamin processing: getting the right bells and whistles Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(35): 13857-8.
Urzica Eugen I, Casero David, Yamasaki Hiroaki, Hsieh Scott I, Adler Lital N, Karpowicz Steven J, Blaby-Haas Crysten E, Clarke Steven G, Loo Joseph A, Pellegrini Matteo, Merchant Sabeeha S   Systems and trans-system level analysis identifies conserved iron deficiency responses in the plant lineage The Plant cell, 2012; 24(10): 3921-48.
McBride Anne E, Zurita-Lopez Cecilia, Regis Anthony, Blum Emily, Conboy Ana, Elf Shannon, Clarke Steven   Protein arginine methylation in Candida albicans: role in nuclear transport Eukaryotic cell, 2007; 6(7): 1119-29.
Urzica Eugen I, Adler Lital N, Page M Dudley, Linster Carole L, Arbing Mark A, Casero David, Pellegrini Matteo, Merchant Sabeeha S, Clarke Steven G   Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase The Journal of biological chemistry, 2012; 287(17): 14234-45.
Lissina Elena, Young Brian, Urbanus Malene L, Guan Xue Li, Lowenson Jonathan, Hoon Shawn, Baryshnikova Anastasia, Riezman Isabelle, Michaut Magali, Riezman Howard, Cowen Leah E, Wenk Markus R, Clarke Steven G, Giaever Guri, Nislow Corey   A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis PLoS genetics, 2011; 7(10): e1002332.
Porras-Yakushi Tanya R, Whitelegge Julian P, Clarke Steven   Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs The Journal of biological chemistry, 2007; 282(17): 12368-76.
Rust Heather L, Zurita-Lopez Cecilia I, Clarke Steven, Thompson Paul R   Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1 Biochemistry, 2011; 50(16): 3332-45.
Butler Jill S, Zurita-Lopez Cecilia I, Clarke Steven G, Bedford Mark T, Dent Sharon Y R   Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes The Journal of biological chemistry, 2011; 286(14): 12234-44.
Vigneswara Vasanthy, Lowenson Jonathan D, Powell Claire D, Thakur Matthew, Bailey Kevin, Clarke Steven, Ray David E, Carter Wayne G   Proteomic identification of novel substrates of a protein isoaspartyl methyltransferase repair enzyme The Journal of biological chemistry, 2006; 281(43): 32619-29.
Porras-Yakushi Tanya R, Whitelegge Julian P, Clarke Steven   A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10 The Journal of biological chemistry, 2006; 281(47): 35835-45.
Chen Tingsu, Nayak Nihar, Majee Susmita Maitra, Lowenson Jonathan, Schäfermeyer Kim R, Eliopoulos Alyssa C, Lloyd Taylor D, Dinkins Randy, Perry Sharyn E, Forsthoefel Nancy R, Clarke Steven G, Vernon Daniel M, Zhou Zhaohui Sunny, Rejtar Tomas, Downie A Bruce   Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning The Journal of biological chemistry, 2010; 285(48): 37281-92.
Yang Mei-Ling, Doyle Hester A, Gee Renelle J, Lowenson Jonathan D, Clarke Steven, Lawson Brian R, Aswad Dana W, Mamula Mark J   Intracellular protein modification associated with altered T cell functions in autoimmunity Journal of immunology (Baltimore, Md. : 1950), 2006; 177(7): 4541-9.
Lipson Rebecca S, Webb Kristofor J, Clarke Steven G   Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae Biochemical and biophysical research communications, 2010; 391(4): 1658-62.
Webb Kristofor J, Laganowsky Arthur, Whitelegge Julian P, Clarke Steven G   Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab The Journal of biological chemistry, 2008; 283(51): 35561-8.
Miranda Tina Branscombe, Sayegh Joyce, Frankel Adam, Katz Jonathan E, Miranda Mark, Clarke Steven   Yeast Hsl7 (histone synthetic lethal 7) catalyses the in vitro formation of omega-N(G)-monomethylarginine in calf thymus histone H2A The Biochemical journal, 2006; 395(3): 563-70.

Timothy Cloughesy, M.D.

Publications

A selected list of publications:

Bryant JA, Finn RS, Slamon DJ, Cloughesy TF, Charles AC   EGF activates intracellular and intercellular calcium signaling by distinct pathways in tumor cells Cancer biology & therapy. , 2004; 3(12): 1243-9.
Graham CA, Cloughesy TF   Brain tumor treatment: chemotherapy and other new developments Seminars in oncology nursing. , 2004; 20(4): 260-72.
Chang SM, Kuhn J, Wen P, Greenberg H, Schiff D, Conrad C, Fink K, Robins HI, Cloughesy T, De Angelis L, Razier J, Hess K, Dancey J, Prados MD   Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs Investigational new drugs. , 2004; 22(4): 427-35.
Puduvalli VK, Yung WK, Hess KR, Kuhn JG, Groves MD, Levin VA, Zwiebel J, Chang SM, Cloughesy TF, Junck L, Wen P, Lieberman F, Conrad CA, Gilbert MR, Meyers CA, Liu V, Mehta MP, Nicholas MK, Prados M   Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study Journal of clinical oncology : official journal of the American Society of Clinical Oncology. , 2004; 22(21): 4282-9.
Mischel PS, Cloughesy TF, Nelson SF   DNA-microarray analysis of brain cancer: molecular classification for therapy Nature reviews. Neuroscience. , 2004; 5(10): 782-92.
Freije WA, Castro-Vargas FE, Fang Z, Horvath S, Cloughesy T, Liau LM, Mischel PS, Nelson SF   Gene expression profiling of gliomas strongly predicts survival Cancer research. , 2004; 64(18): 6503-10.
Kaleita TA, Wellisch DK, Cloughesy TF, Ford JM, Freeman D, Belin TR, Goldman J   Prediction of neurocognitive outcome in adult brain tumor patients Journal of neuro-oncology. , 2004; 67(1-2): 245-53.
Wang Y, Zhu S, Cloughesy TF, Liau LM, Mischel PS   p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition Oncogene. , 2004; 23(6): 1283-90.
Parker RJ, Fruehauf JP, Mehta R, Filka E, Cloughesy T   A prospective blinded study of the predictive value of an extreme drug resistance assay in patients receiving CPT-11 for recurrent glioma Journal of neuro-oncology. , 2004; 66(3): 365-75.
Prados MD, Yung WK, Jaeckle KA, Robins HI, Mehta MP, Fine HA, Wen PY, Cloughesy TF, Chang SM, Nicholas MK, Schiff D, Greenberg HS, Junck L, Fink KL, Hess KR, Kuhn J   Phase 1 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study Neuro-oncology. , 2004; 6(1): 44-54.
Lu KV, Jong KA, Rajasekaran AK, Cloughesy TF, Mischel PS   Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line Laboratory investigation; a journal of technical methods and pathology. , 2004; 84(1): 8-20.
Shai R, Shi T, Kremen TJ, Horvath S, Liau LM, Cloughesy TF, Mischel PS, Nelson SF   Gene expression profiling identifies molecular subtypes of gliomas Oncogene. , 2003; 22(31): 4918-23.
Mischel PS, Nelson SF, Cloughesy TF   Molecular analysis of glioblastoma: pathway profiling and its implications for patient therapy Cancer biology & therapy. , 2003; 2(3): 242-7.
Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF   Oncodiagnosis panel: 2002. Metastatic NSCLC Radiographics : a review publication of the Radiological Society of North America, Inc. , 2003; 23(6): 1591-611.
Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF   Oncodiagnosis panel: 2002. Optic nerve glioma or optic nerve meningioma Radiographics, 2003; 23(6): 1591-611.
Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF   Oncodiagnosis panel: 2002. Patient’s symptoms not related to the lesion seen in the MR images Radiographics, 2003; 23(6): 1591-611.
Brown PD, Wald JT, McDermott MW, Baumann GS, Cloughesy TF   Oncodiagnosis panel: 2002. Primary glial neoplasm or less likely an intracranial abscess Radiographics : a review publication of the Radiological Society of North America, Inc. , 2003; 23(6): 1591-611.
Jaeckle KA, Hess KR, Yung WK, Greenberg H, Fine H, Schiff D, Pollack IF, Kuhn J, Fink K, Mehta M, Cloughesy T, Nicholas MK, Chang S, Prados M   Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study Journal of clinical oncology : official journal of the American Society of Clinical Oncology. , 2003; 21(12): 2305-11.
Mischel PS, Cloughesy TF   Targeted molecular therapy of GBM Brain Pathol, 2003; 13(1): 52-61.
Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS   Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo Cancer research. , 2003; 63(11): 2742-6.
Cloughesy TF, Filka E, Kuhn J, Nelson G, Kabbinavar F, Friedman H, Miller LL, Elfring GL   Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen Cancer. , 2003; 97(9 Suppl): 2381-6.
Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM, Cloughesy TF, Nelson SF   Identification of molecular subtypes of glioblastoma by gene expression profiling Oncogene. , 2003; 22(15): 2361-73.

Michelle Craske, Ph.D.

Publications

A selected list of publications:

Wolitzky-Taylor Kate, Bobova Lyuba, Zinbarg Richard E, Mineka Susan, Craske Michelle G   Longitudinal investigation of the impact of anxiety and mood disorders in adolescence on subsequent substance use disorder onset and vice versa Addictive behaviors, 2012; 37(8): 982-5.
Arch Joanna J, Wolitzky-Taylor Kate B, Eifert Georg H, Craske Michelle G   Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders Behaviour research and therapy, 2012; 50(7-8): 469-78.
Lang Ariel J, Wilkins Kendall, Roy-Byrne Peter P, Golinelli Daniela, Chavira Denise, Sherbourne Cathy, Rose Raphael D, Bystritsky Alexander, Sullivan Greer, Craske Michelle G, Stein Murray B   Abbreviated PTSD Checklist (PCL) as a guide to clinical response General hospital psychiatry, 2012; 34(4): 332-8.
Kircanski Katharina, Mortazavi Arezou, Castriotta Natalie, Baker Aaron S, Mystkowski Jayson L, Yi Rena, Craske Michelle G   Challenges to the traditional exposure paradigm: variability in exposure therapy for contamination fears Journal of behavior therapy and experimental psychiatry, 2012; 43(2): 745-51.
Meuret Alicia E, Wolitzky-Taylor Kate B, Twohig Michael P, Craske Michelle G   Coping skills and exposure therapy in panic disorder and agoraphobia: latest advances and future directions Behavior therapy, 2012; 43(2): 271-84.
Culver Najwa C, Stoyanova Milena, Craske Michelle G   Emotional variability and sustained arousal during exposure Journal of behavior therapy and experimental psychiatry, 2012; 43(2): 787-93.
Mohlman Jan, Bryant Christina, Lenze Eric J, Stanley Melinda A, Gum Amber, Flint Alastair, Beekman Aartjan T F, Wetherell Julie Loebach, Thorp Steven R, Craske Michelle G   Improving recognition of late life anxiety disorders in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition: observations and recommendations of the Advisory Committee to the Lifespan Disorders Work Group International journal of geriatric psychiatry, 2012; 27(6): 549-56.
Rapee Ronald M, Bőgels Susan M, van der Sluis Cathy M, Craske Michelle G, Ollendick Thomas   Annual research review: conceptualising functional impairment in children and adolescents Journal of child psychology and psychiatry, and allied disciplines, 2012; 53(5): 454-68.
Stein Alan, Murphy Susannah, Arteche Adriane, Lehtonen Annukka, Harvey Allison, Craske Michelle G, Harmer Catherine   Effects of reboxetine and citalopram on appraisal of infant facial expressions and attentional biases Journal of psychopharmacology (Oxford, England), 2012; 26(5): 670-6.
Craske Michelle G, Wolitzky-Taylor Kate B, Mineka Susan, Zinbarg Richard, Waters Allison M, Vrshek-Schallhorn Suzanne, Epstein Alyssa, Naliboff Bruce, Ornitz Edward   Elevated responding to safe conditions as a specific risk factor for anxiety versus depressive disorders: evidence from a longitudinal investigation Journal of abnormal psychology, 2012; 121(2): 315-24.
Arch Joanna J, Eifert Georg H, Davies Carolyn, Vilardaga Jennifer C Plumb, Rose Raphael D, Craske Michelle G   Randomized Clinical Trial of Cognitive Behavioral Therapy (CBT) Versus Acceptance and Commitment Therapy (ACT) for Mixed Anxiety Disorders Journal of consulting and clinical psychology, 2012; 43(2): .
Bystritsky Alexander, Hovav Sarit, Sherbourne Cathy, Stein Murray B, Rose Raphael D, Campbell-Sills Laura, Golinelli Daniela, Sullivan Greer, Craske Michelle G, Roy-Byrne Peter P   Use of complementary and alternative medicine in a large sample of anxiety patients Psychosomatics, 2012; 53(3): 266-72.
Curran Geoffrey M, Sullivan Greer, Mendel Peter, Craske Michelle G, Sherbourne Cathy D, Stein Murray B, McDaniel Ashley, Roy-Byrne Peter   Implementation of the CALM intervention for anxiety disorders: a qualitative study Implementation science : IS, 2012; 7(4): 1-11.
Craske Michelle G   The R-DoC initiative: science and practice Depression and anxiety, 2012; 29(4): 253-6.
Niles Andrea N, Lebeau Richard T, Liao Betty, Glenn Daniel E, Craske Michelle G   Dimensional indicators of generalized anxiety disorder severity for DSM-V Journal of anxiety disorders, 2012; 26(2): 279-86.
Uliaszek Amanda A, Zinbarg Richard E, Mineka Susan, Craske Michelle G, Griffith James W, Sutton Jonathan M, Epstein Alyssa, Hammen Constance   A longitudinal examination of stress generation in depressive and anxiety disorders Journal of abnormal psychology, 2012; 121(1): 4-15.
Prenoveau Jason M, Craske Michelle G, Liao Betty, Ornitz Edward M   Human fear conditioning and extinction: Timing is everything…or is it? Biological psychology, 2012; 26(2): .
Stein Alan, Craske Michelle G, Lehtonen Annukka, Harvey Allison, Savage-McGlynn Emily, Davies Beverley, Goodwin Julia, Murray Lynne, Cortina-Borja Mario, Counsell Nicholas   Maternal cognitions and mother-infant interaction in postnatal depression and generalized anxiety disorder Journal of abnormal psychology, 2012; 121(1): .
Dear Blake F, Titov Nickolai, Schwencke Genevieve, Andrews Gavin, Johnston Luke, Craske Michelle G, McEvoy Peter   An open trial of a brief transdiagnostic internet treatment for anxiety and depression Behaviour research and therapy, 2011; 49(12): 830-7.
Ries Richard, Wolitzky-Taylor Kate B, Operskalski Joachim T, Craske Michelle G, Roy-Byrne Peter   Treatment of comorbid substance use and anxiety disorders: a case study Journal of addiction medicine, 2011; 5(4): 248-53.
Wolitzky-Taylor Kate, Operskalski Joachim T, Ries Richard, Craske Michelle G, Roy-Byrne Peter   Understanding and treating comorbid anxiety disorders in substance users: review and future directions Journal of addiction medicine, 2011; 5(4): 233-47.
Prenoveau Jason M, Craske Michelle G, Zinbarg Richard E, Mineka Susan, Rose Raphael D, Griffith James W   Are anxiety and depression just as stable as personality during late adolescence? Results from a three-year longitudinal latent variable study Journal of abnormal psychology, 2011; 120(4): 832-43.
Arteche Adriane, Joormann Jutta, Harvey Allison, Craske Michelle, Gotlib Ian H, Lehtonen Annukka, Counsell Nicholas, Stein Alan   The effects of postnatal maternal depression and anxiety on the processing of infant faces Journal of affective disorders, 2011; 133(1-2): 197-203.
Stein Dan J, Craske Michelle G, Friedman Matthew J, Phillips Katharine A   Meta-structure issues for the DSM-5: how do anxiety disorders, obsessive-compulsive and related disorders, post-traumatic disorders, and dissociative disorders fit together? Current psychiatry reports, 2011; 13(4): 248-50.
Sutton Jonathan M, Mineka Susan, Zinbarg Richard E, Craske Michelle G, Griffith James W, Rose Raphael D, Waters Allison M, Nazarian Maria, Mor Nilly   The Relationships of Personality and Cognitive Styles with Self-Reported Symptoms of Depression and Anxiety Cognitive therapy and research, 2011; 35(4): 381-393.
Rose Raphael D, Lang Ariel J, Welch Stacy Shaw, Campbell-Sills Laura, Chavira Denise A, Sullivan Greer, Sherbourne Cathy, Bystritsky Alexander, Stein Murray B, Roy-Byrne Peter P, Craske Michelle G   Training primary care staff to deliver a computer-assisted cognitive-behavioral therapy program for anxiety disorders General hospital psychiatry, 2011; 33(4): 336-42.
Titov Nickolai, Dear Blake F, Schwencke Genevieve, Andrews Gavin, Johnston Luke, Craske Michelle G, McEvoy Peter   Transdiagnostic internet treatment for anxiety and depression: a randomised controlled trial Behaviour research and therapy, 2011; 49(8): 441-52.
Stein Murray B, Roy-Byrne Peter P, Craske Michelle G, Campbell-Sills Laura, Lang Ariel J, Golinelli Daniella, Rose Raphael D, Bystritsky Alexander, Sullivan Greer, Sherbourne Cathy D   Quality of and patient satisfaction with primary health care for anxiety disorders The Journal of clinical psychiatry, 2011; 72(7): 970-6.
Craske Michelle G, Wolitzky-Taylor Kate B, Labus Jennifer, Wu Stephen, Frese Michael, Mayer Emeran A, Naliboff Bruce D   A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations Behaviour research and therapy, 2011; 49(6-7): 413-21.
Vrshek-Schallhorn Suzanne, Czarlinski Jennifer, Mineka Susan, Zinbarg Richard E, Craske Michelle   Prospective Predictors of Suicidal Ideation during Depressive Episodes among Older Adolescents and Young Adults Personality and individual differences, 2011; 50(8): 1202-1207.
Craske Michelle G, Stein Murray B, Sullivan Greer, Sherbourne Cathy, Bystritsky Alexander, Rose Raphael D, Lang Ariel J, Welch Stacy, Campbell-Sills Laura, Golinelli Daniela, Roy-Byrne Peter   Disorder-specific impact of coordinated anxiety learning and management treatment for anxiety disorders in primary care Archives of general psychiatry, 2011; 68(4): 378-88.
Culver Najwa C, Stoyanova Milena, Craske Michelle G   Clinical relevance of retrieval cues for attenuating context renewal of fear Journal of anxiety disorders, 2011; 25(2): 284-92.
Stevens Stephan, Gerlach Alexander L, Cludius Barbara, Silkens Anna, Craske Michelle G, Hermann Christiane   Heartbeat perception in social anxiety before and during speech anticipation Behaviour research and therapy, 2011; 49(2): 138-43.
Sumner Jennifer A, Griffith James W, Mineka Susan, Rekart Kathleen Newcomb, Zinbarg Richard E, Craske Michelle G   Overgeneral autobiographical memory and chronic interpersonal stress as predictors of the course of depression in adolescents Cognition & emotion, 2011; 25(1): 183-92.
Andrews Gavin, Cuijpers Pim, Craske Michelle G, McEvoy Peter, Titov Nickolai   Computer therapy for the anxiety and depressive disorders is effective, acceptable and practical health care: a meta-analysis PloS one, 2010; 5(10): e13196.
Baker Aaron, Mystkowski Jayson, Culver Najwa, Yi Rena, Mortazavi Arezou, Craske Michelle G   Does habituation matter? Emotional processing theory and exposure therapy for acrophobia Behaviour research and therapy, 2010; 48(11): 1139-43.
Lewis Alison R, Zinbarg Richard E, Mineka Susan, Craske Michelle G, Epstein Alyssa, Griffith James W   The relationship between anxiety sensitivity and latent symptoms of emotional problems: A structural equation modeling approach Behaviour research and therapy, 2010; 48(8): 761-9.
Adam Emma K, Doane Leah D, Zinbarg Richard E, Mineka Susan, Craske Michelle G, Griffith James W   Prospective prediction of major depressive disorder from cortisol awakening responses in adolescence Psychoneuroendocrinology, 2010; 35(6): 921-31.
Uliaszek Amanda A, Zinbarg Richard E, Mineka Susan, Craske Michelle G, Sutton Jonathan M, Griffith James W, Rose Raphael, Waters Allison, Hammen Constance   The role of neuroticism and extraversion in the stress-anxiety and stress-depression relationships Anxiety, stress, and coping, 2010; 23(4): 363-81.
Stein Alan, Arteche Adriane, Lehtonen Annukka, Craske Michelle, Harvey Allison, Counsell Nicholas, Murray Lynne   Interpretation of infant facial expression in the context of maternal postnatal depression Infant behavior & development, 2010; 33(3): 273-8.
Arch Joanna J, Craske Michelle G   Laboratory stressors in clinically anxious and non-anxious individuals: the moderating role of mindfulness Behaviour research and therapy, 2010; 48(6): 495-505.
Roy-Byrne Peter, Craske Michelle G, Sullivan Greer, Rose Raphael D, Edlund Mark J, Lang Ariel J, Bystritsky Alexander, Welch Stacy Shaw, Chavira Denise A, Golinelli Daniela, Campbell-Sills Laura, Sherbourne Cathy D, Stein Murray B   Delivery of evidence-based treatment for multiple anxiety disorders in primary care: a randomized controlled trial JAMA : the journal of the American Medical Association, 2010; 303(19): 1921-8.
Zinbarg Richard E, Mineka Susan, Craske Michelle G, Griffith James W, Sutton Jonathan, Rose Raphael D, Nazarian Maria, Mor Nilly, Waters Allison M   The Northwestern-UCLA youth emotion project: Associations of cognitive vulnerabilities, neuroticism and gender with past diagnoses of emotional disorders in adolescents Behaviour research and therapy, 2010; 48(5): 347-58.
Rudaz Myriam, Craske Michelle G, Becker Eni S, Ledermann Thomas, Margraf Jürgen   Health anxiety and fear of fear in panic disorder and agoraphobia vs. social phobia: a prospective longitudinal study Depression and anxiety, 2010; 27(4): 404-11.
Prenoveau Jason M, Zinbarg Richard E, Craske Michelle G, Mineka Susan, Griffith James W, Epstein Alyssa M   Testing a hierarchical model of anxiety and depression in adolescents: a tri-level model Journal of anxiety disorders, 2010; 24(3): 334-44.
Wittchen Hans-Ulrich, Gloster Andrew T, Beesdo-Baum Katja, Fava Giovanni A, Craske Michelle G   Agoraphobia: a review of the diagnostic classificatory position and criteria Depression and anxiety, 2010; 27(2): 113-33.
Wolitzky-Taylor Kate B, Castriotta Natalie, Lenze Eric J, Stanley Melinda A, Craske Michelle G   Anxiety disorders in older adults: a comprehensive review Depression and anxiety, 2010; 27(2): 190-211.
Lewis-Fernández Roberto, Hinton Devon E, Laria Amaro J, Patterson Elissa H, Hofmann Stefan G, Craske Michelle G, Stein Dan J, Asnaani Anu, Liao Betty   Culture and the anxiety disorders: recommendations for DSM-V Depression and anxiety, 2010; 27(2): 212-29.
Andrews Gavin, Hobbs Megan J, Borkovec Thomas D, Beesdo Katja, Craske Michelle G, Heimberg Richard G, Rapee Ronald M, Ruscio Ayelet Meron, Stanley Melinda A   Generalized worry disorder: a review of DSM-IV generalized anxiety disorder and options for DSM-V Depression and anxiety, 2010; 27(2): 134-47.
Craske Michelle G, Kircanski Katharina, Epstein Alyssa, Wittchen Hans-Ulrich, Pine Danny S, Lewis-Fernández Roberto, Hinton Devon, Hinton Devon, Hinton Devon, Hinton Devon   Panic disorder: a review of DSM-IV panic disorder and proposals for DSM-V Depression and anxiety, 2010; 27(2): 93-112.
Phillips Katharine A, Friedman Matthew J, Stein Dan J, Craske Michelle   Special DSM-V issues on anxiety, obsessive-compulsive spectrum, posttraumatic, and dissociative disorders Depression and anxiety, 2010; 27(2): 91-2.
LeBeau Richard T, Glenn Daniel, Liao Betty, Wittchen Hans-Ulrich, Beesdo-Baum Katja, Ollendick Thomas, Craske Michelle G   Specific phobia: a review of DSM-IV specific phobia and preliminary recommendations for DSM-V Depression and anxiety, 2010; 27(2): 148-67.
Craske Michelle G, Roy-Byrne Peter P, Stein Murray B, Sullivan Greer, Sherbourne Cathy, Bystritsky Alexander   Treatment for anxiety disorders: Efficacy to effectiveness to implementation Behaviour research and therapy, 2009; 47(11): 931-7.
Uliaszek Amanda A, Hauner Katherina K Y, Zinbarg Richard E, Craske Michelle G, Mineka Susan, Griffith James W, Rose Raphael D   An Examination of Content Overlap and Disorder-Specific Predictions in the Associations of Neuroticism with Anxiety and Depression Journal of research in personality, 2009; 43(5): 785-794.
Chavira Denise A, Stein Murray B, Golinelli Daniela, Sherbourne Cathy D, Craske Michelle G, Sullivan Greer, Bystritsky Alexander, Roy-Byrne Peter P   Predictors of clinical improvement in a randomized effectiveness trial for primary care patients with panic disorder The Journal of nervous and mental disease, 2009; 197(10): 715-21.
Prenoveau Jason M, Zinbarg Richard E, Craske Michelle G, Mineka Susan, Griffith James W, Rose Raphael D   Evaluating the invariance and validity of the structure of dysfunctional attitudes in an adolescent population Assessment, 2009; 16(3): 258-73.
Arch Joanna J, Craske Michelle G   First-line treatment: a critical appraisal of cognitive behavioral therapy developments and alternatives The Psychiatric clinics of North America, 2009; 32(3): 525-47.
Griffith James W, Sumner Jennifer A, Debeer Elise, Raes Filip, Hermans Dirk, Mineka Susan, Zinbarg Richard E, Craske Michelle G   An item response theory/confirmatory factor analysis of the Autobiographical Memory Test Memory (Hove, England), 2009; 17(6): 609-23.
Roy-Byrne Peter, Veitengruber Jason P, Bystritsky Alexander, Edlund Mark J, Sullivan Greer, Craske Michelle G, Welch Stacy Shaw, Rose Raphael, Stein Murray B   Brief intervention for anxiety in primary care patients Journal of the American Board of Family Medicine : JABFM, 2009; 22(2): 175-86.
Twiss Christian, Kilpatrick Lisa, Craske Michelle, Buffington C A Tony, Ornitz Edward, Rodríguez Larissa V, Mayer Emeran A, Naliboff Bruce D   Increased startle responses in interstitial cystitis: evidence for central hyperresponsiveness to visceral related threat The Journal of urology, 2009; 181(5): 2127-33.
Craske Michelle G, Rose Raphael D, Lang Ariel, Welch Stacy Shaw, Campbell-Sills Laura, Sullivan Greer, Sherbourne Cathy, Bystritsky Alexander, Stein Murray B, Roy-Byrne Peter P   Computer-assisted delivery of cognitive behavioral therapy for anxiety disorders in primary-care settings Depression and anxiety, 2009; 26(3): 235-42.
Craske Michelle G, Waters Allison M, Nazarian Maria, Mineka Susan, Zinbarg Richard E, Griffith James W, Naliboff Bruce, Ornitz Edward M   Does neuroticism in adolescents moderate contextual and explicit threat cue modulation of the startle reflex? Biological psychiatry, 2009; 65(3): 220-6.
Lehtonen Annukka, Jakub Natasha, Craske Michelle, Doll Helen, Harvey Allison, Stein Alan   Effects of preoccupation on interpersonal recall: a pilot study Depression and anxiety, 2009; 26(1): 1-6.
Kircanski Katharina, Craske Michelle G, Epstein Alyssa M, Wittchen Hans-Ulrich   Subtypes of panic attacks: a critical review of the empirical literature Depression and anxiety, 2009; 26(10): 878-87.
Craske Michelle G, Rauch Scott L, Ursano Robert, Prenoveau Jason, Pine Daniel S, Zinbarg Richard E   What is an anxiety disorder? Depression and anxiety, 2009; 26(12): 1066-85.
Stein Alan, Lehtonen Annukka, Harvey Allison G, Nicol-Harper Rosie, Craske Michelle   The influence of postnatal psychiatric disorder on child development. Is maternal preoccupation one of the key underlying processes? Psychopathology, 2009; 42(1): 11-21.
Campbell-Sills Laura, Norman Sonya B, Craske Michelle G, Sullivan Greer, Lang Ariel J, Chavira Denise A, Bystritsky Alexander, Sherbourne Cathy, Roy-Byrne Peter, Stein Murray B   Validation of a brief measure of anxiety-related severity and impairment: the Overall Anxiety Severity and Impairment Scale (OASIS) Journal of affective disorders, 2009; 112(1-3): 92-101.
Waters Allison M, Craske Michelle G, Bergman R Lindsey, Naliboff Bruce D, Negoro Hideki, Ornitz Edward M   Developmental changes in startle reactivity in school-age children at risk for and with actual anxiety disorder International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2008; 70(3): 158-64.
Hauner Katherina K Y, Adam Emma K, Mineka Susan, Doane Leah D, DeSantis Amy S, Zinbarg Richard, Craske Michelle, Griffith James W   Neuroticism and introversion are associated with salivary cortisol patterns in adolescents Psychoneuroendocrinology, 2008; 33(10): 1344-56.
Naliboff Bruce D, Waters Allison M, Labus Jennifer S, Kilpatrick Lisa, Craske Michelle G, Chang Lin, Negoro Hideki, Ibrahimovic Hana, Mayer Emeran A, Ornitz Edward   Increased acoustic startle responses in IBS patients during abdominal and nonabdominal threat Psychosomatic medicine, 2008; 70(8): 920-7.
Story Tyler J, Craske Michelle G   Responses to false physiological feedback in individuals with panic attacks and elevated anxiety sensitivity Behaviour research and therapy, 2008; 46(9): 1001-8.
Craske Michelle G, Waters Allison M, Lindsey Bergman R, Naliboff Bruce, Lipp Ottmar V, Negoro Hideki, Ornitz Edward M   Is aversive learning a marker of risk for anxiety disorders in children? Behaviour research and therapy, 2008; 46(8): 954-67.
Tabibnia Golnaz, Lieberman Matthew D, Craske Michelle G   The lasting effect of words on feelings: words may facilitate exposure effects to threatening images Emotion (Washington, D.C.), 2008; 8(3): 307-17.
Waters Allison M, Neumann David L, Henry Julie, Craske Michelle G, Ornitz Edward M   Baseline and affective startle modulation by angry and neutral faces in 4-8-year-old anxious and non-anxious children Biological psychology, 2008; 78(1): 10-9.
Kircanski Katharina, Craske Michelle G, Bjork Robert A   Thought suppression enhances memory bias for threat material Behaviour research and therapy, 2008; 46(4): 462-76.
Kringelbach Morten L, Lehtonen Annukka, Squire Sarah, Harvey Allison G, Craske Michelle G, Holliday Ian E, Green Alexander L, Aziz Tipu Z, Hansen Peter C, Cornelissen Piers L, Stein Alan   A specific and rapid neural signature for parental instinct PloS one, 2008; 3(2): e1664.
Waters Allison M, Wharton Trisha A, Zimmer-Gembeck Melanie J, Craske Michelle G   Threat-based cognitive biases in anxious children: comparison with non-anxious children before and after cognitive behavioural treatment Behaviour research and therapy, 2008; 46(3): 358-74.
Sullivan Greer, Craske Michelle G, Sherbourne Cathy, Edlund Mark J, Rose Raphael D, Golinelli Daniela, Chavira Denise A, Bystritsky Alexander, Stein Murray B, Roy-Byrne Peter P   Design of the Coordinated Anxiety Learning and Management (CALM) study: innovations in collaborative care for anxiety disorders General hospital psychiatry, 2008; 29(5): 379-87.
Mor Nilly, Zinbarg Richard E, Craske Michelle G, Mineka Susan, Uliaszek Amanda, Rose Raphael, Griffith James W, Waters Allison M   Evaluating the invariance of the factor structure of the EPQ-R-N among adolescents Journal of personality assessment, 2008; 90(1): 66-75.
Craske Michelle G, Kircanski Katharina, Zelikowsky Moriel, Mystkowski Jayson, Chowdhury Najwa, Baker Aaron   Optimizing inhibitory learning during exposure therapy Behaviour research and therapy, 2008; 46(1): 5-27.
Means-Christensen Adrienne J, Roy-Byrne Peter P, Sherbourne Cathy D, Craske Michelle G, Stein Murray B   Relationships among pain, anxiety, and depression in primary care Depression and anxiety, 2008; 25(7): 593-600.
Aikins Deane E, Craske Michelle G   Sleep-based heart period variability in panic disorder with and without nocturnal panic attacks Journal of anxiety disorders, 2008; 22(3): 453-63.
Waters Allison M, Craske Michelle G, Bergman R Lindsey, Treanor Michael   Threat interpretation bias as a vulnerability factor in childhood anxiety disorders Behaviour research and therapy, 2008; 46(1): 39-47.
Arch Joanna J, Craske Michelle G   Implications of naturalistic use of pharmacotherapy in CBT treatment for panic disorder Behaviour research and therapy, 2007; 45(7): 1435-47.
DeSantis Amy S, Adam Emma K, Doane Leah D, Mineka Susan, Zinbarg Richard E, Craske Michelle G   Racial/ethnic differences in cortisol diurnal rhythms in a community sample of adolescents The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2007; 41(1): 3-13.
Craske Michelle G, Farchione Todd J, Allen Laura B, Barrios Velma, Stoyanova Milena, Rose Raphael   Cognitive behavioral therapy for panic disorder and comorbidity: more of the same or less of more? Behaviour research and therapy, 2007; 45(6): 1095-109.
Bricker Jonathan B, Russo Joan, Stein Murray B, Sherbourne Cathy, Craske Michelle, Schraufnagel Trevor J, Roy-Byrne Peter   Does occasional cannabis use impact anxiety and depression treatment outcomes?: Results from a randomized effectiveness trial Depression and anxiety, 2007; 24(6): 392-8.
Waters Allison M, Nitz Ashley B, Craske Michelle G, Johnson Chris   The effects of anxiety upon attention allocation to affective stimuli Behaviour research and therapy, 2007; 45(4): 763-74.
Mukherjee Snigdha, Sullivan Greer, Perry Dana, Verdugo Bobby, Means-Christensen Adrienne, Schraufnagel Trevor, Sherbourne Cathy D, Stein Murray B, Craske Michelle G, Roy-Byrne Peter P   Adherence to treatment among economically disadvantaged patients with panic disorder Psychiatric services (Washington, D.C.), 2006; 57(12): 1745-50.
Arch Joanna J, Craske Michelle G   Mechanisms of mindfulness: emotion regulation following a focused breathing induction Behaviour research and therapy, 2006; 44(12): 1849-58.
Roy-Byrne Peter P, Craske Michelle G, Stein Murray B   Panic disorder Lancet, 2006; 368(9540): 1023-32.
Demertzis Kristen Hope, Craske Michelle G   Anxiety in primary care Current psychiatry reports, 2006; 8(4): 291-7.
Norman Sonya B, Means-Christensen Adrienne J, Craske Michelle G, Sherbourne Cathy D, Roy-Byrne Peter P, Stein Murray B   Associations between psychological trauma and physical illness in primary care Journal of traumatic stress, 2006; 19(4): 461-70.
Hermans Dirk, Craske Michelle G, Mineka Susan, Lovibond Peter F   Extinction in human fear conditioning Biological psychiatry, 2006; 60(4): 361-8.
Roy-Byrne Peter, Sherbourne Cathy, Miranda Jeanne, Stein Murray, Craske Michelle, Golinelli Daniela, Sullivan Greer   Poverty and response to treatment among panic disorder patients in primary care The American journal of psychiatry, 2006; 163(8): 1419-25.
Craske Michelle G, Roy-Byrne Peter, Stein Murray B, Sullivan Greer, Hazlett-Stevens Holly, Bystritsky Alexander, Sherbourne Cathy   CBT intensity and outcome for panic disorder in a primary care setting Behavior therapy, 2006; 37(2): 112-9.
Katon Wayne, Russo Joan, Sherbourne Cathy, Stein Murray B, Craske Michelle, Fan Ming-Yu, Roy-Byrne Peter   Incremental cost-effectiveness of a collaborative care intervention for panic disorder Psychological medicine, 2006; 36(3): 353-63.
Mystkowski Jayson L, Craske Michelle G, Echiverri Aileen M, Labus Jennifer S   Mental reinstatement of context and return of fear in spider-fearful participants Behavior therapy, 2006; 37(1): 49-60.
Means-Christensen Adrienne J, Sherbourne Cathy D, Roy-Byrne Peter P, Craske Michelle G, Stein Murray B   Using five questions to screen for five common mental disorders in primary care: diagnostic accuracy of the Anxiety and Depression Detector General hospital psychiatry, 2006; 28(2): 108-18.
Zucker Bonnie G, Craske Michelle G, Blackmore Michelle A, Nitz Ashley   A cognitive behavioral workshop for subclinical obsessions and compulsions Behaviour research and therapy, 2006; 44(2): 289-304.