Posts classified under: K

Achuta Kadambi, Ph.D.

Achuta Kadambi received the PhD degree from MIT and joined UCLA as an Assistant Professor. His publications have been presented as Orals at CVPR, ICCV, ICCP and SIGGRAPH. He is currently co-authoring a textbook (“Computational Imaging”, MIT Press 2021) and is also a co-founder in a robotic imaging startup (http://akasha.im). Achuta’s research has received several recognitions including the NSF CAREER Award, Forbes 30 under 30 (Science), Google Faculty Award, Sony Imaging Young Faculty Award, and Army Young Investigator Award (ARO-YIP).

H. Ronald Kaback, M.D.

Biography

H. Ronald Kaback has been a member of the faculty at UCLA since he joined the Depts. of Physiology and Microbiology, Immunology & Molecular Genetics, as well as the Molecular Biology Institute, in 1989 as a full professor. Dr. Kaback earned his B.S. at Haverford College and his M.D. at The Albert Einstein College of Medicine, where he also did an internship in Pediatrics. After a year as a graduate student, he became a Commissioned Officer in the USPHS at the NIH and subsequently became at Staff Associate. He then moved to the Roche Institute of Molecular Biology in Nutley, NJ where he later became Head of Biochemistry before coming to UCLA. He is a member of the National Academy of Science and is the recipient of many awards for his work.

Publications

A selected list of publications:

Zhou, Y. Guan, L. Kaback, H. R.   Opening and closing of the periplasmic gate in lactose permease, Proc Natl Acad Sci U S A, 2008; in press.
Nie, Y. Ermolova, N. Kaback, H. R.   Site-directed Alkylation of LacY: Effect of the Proton Electrochemical Gradient J Mol Biol, 2007; 374(2): 356-64.
Smirnova, I. Kasho, V. Choe, J. Y. Altenbach, C. Hubbell, W. L. Kaback, H. R.   Sugar binding induces an outward facing conformation of LacY Proc Natl Acad Sci U S A, 2007; 104: 16504-16509.
Guan, L. Mirza, O. Verner, G. Iwata, S. Kaback, H. R.   Structural determination of wild-type lactose permease Proc Natl Acad Sci U S A, 2007; 104(39): 15294-8.
Majumdar, D. S. Smirnova, I. Kasho, V. Nir, E. Kong, X. Weiss, S. Kaback, H. R.   Single-molecule FRET reveals sugar-induced conformational dynamics in LacY Proc Natl Acad Sci U S A, 2007; 104(31): 12640-12645.
Guan, L. Kaback, H. R.   Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins Nat Protoc, 2007; 2(8): 2012-7.
Shimohata, N. Nagamori, S. Akiyama, Y. Kaback, H. R. Ito, K.   SecY alterations that impair membrane protein folding and generate a membrane stress J Cell Biol, 2007; 176(3): 307-17.
Smirnova, I. N. Kasho, V. N. Kaback, H. R.   Direct Sugar Binding to LacY Measured by Resonance Energy Transfer Biochemistry, 2006; 45(51): 15279-87.
Kaback, H. R. Dunten, R. Frillingos, S. Venkatesan, P. Kwaw, I. Zhang, W. Ermolova, N.   Site-directed alkylation and the alternating access model for LacY Proc Natl Acad Sci U S A, 2006; .
Guan, L. Kaback, H. R.   Lessons from Lactose Permease Annu Rev Biophys Biomol Struct, 2006; 35: 67-91.
Nie, Y. Smirnova, I. Kasho, V. Kaback, H. R.   Energetics of Ligand-induced Conformational Flexibility in the Lactose Permease of Escherichia coli J Biol Chem, 2006; 281(47): 35779-84.
Vadyvaloo, V. Smirnova, I. N. Kasho, V. N. Kaback, H. Ronald   Conservation of residues involved in sugar/H(+) symport by the sucrose permease of Escherichia coli relative to lactose permease J Mol Biol, 2006; 358(4): 1051-9.
Kasho, V. N. Smirnova, I. N. Kaback, H. R.   Sequence alignment and homology threading reveals prokaryotic and eukaryotic proteins similar to lactose permease J Mol Biol, 2006; 358(4): 1060-70.
Ermolova, N. Madhvani, R. V. Kaback, H. R.   Site-directed alkylation of cysteine replacements in the lactose permease of Escherichia coli: helices I, III, VI, and XI Biochemistry, 2006; 45(13): 4182-9.
Mirza, O. 2006)200251183Guan, L. Verner, G. Iwata, S. Kaback, H. R.   Structural evidence for induced fit and a mechanism for sugar/H(+) symport in LacY Embo J, 2006; 25: 1177-1183.
Guan, L. Smirnova, I. N. Verner, G. Nagamoni, S. Kaback, H. R.   Manipulating phospholipids for crystallization of a membrane transport protein Proc Natl Acad Sci U S A, 2006; 103(6): 1723-6.
Kaback, H. R.   Structure and mechanism of the lactose permease C R Biol, 2005; 328(6): 557-67.
Kaback, H. R   The Passion of the Permease, Biophysical and Structural Aspects of Bioenergetics, 2005; 359-373.
Ermolova, N. V. Smirnova, I. N. Kasho, V. N. Kaback, H. R.   Interhelical packing modulates conformational flexibility in the lactose permease of Escherichia coli Biochemistry, 2005; 44(21): 7669-77.
van Bloois, E. Nagamori, S. Koningstein, G. Ullers, R. S. Preuss, M. Oudega, B. Harms, N. Kaback, H. R. Herrmann, J. M. Luirink, J.   The Sec-independent function of Escherichia coli YidC is evolutionary-conserved and essential J Biol Chem, 2005; 280(13): 12996-3003.
Weinglass, A. B. Soskine, M. Vazquez-Ibar, J. L. Whitelegge, J. P. Faull, K. F. Kaback, H. R. Schuldiner, S.   Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry J Biol Chem, 2005; 280(9): 7487-92.
Sun, J. Savva, C. G. Deaton, J. Kaback, H. R. Svrakic, M. Young, R. Holzenburg, A.   Asymmetric binding of membrane proteins to GroEL Arch Biochem Biophys, 2005; 434(2): 352-7.

Pamela Kennedy, Ph.D.

Publications

A selected list of publications:

Dietz David M, Kennedy Pamela J, Sun Haosheng, Maze Ian, Gancarz Amy M, Vialou Vincent, Koo Ja Wook, Mouzon Ezekiell, Ghose Subroto, Tamminga Carol A, Nestler Eric J   Î”FosB Induction in Prefrontal Cortex by Antipsychotic Drugs is Associated with Negative Behavioral Outcomes Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013; .
Kennedy Pamela J, Feng Jian, Robison A J, Maze Ian, Badimon Ana, Mouzon Ezekiell, Chaudhury Dipesh, Damez-Werno Diane M, Haggarty Stephen J, Han Ming-Hu, Bassel-Duby Rhonda, Olson Eric N, Nestler Eric J   Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation Nature neuroscience, 2013; 16(4): 434-40.
Sun HaoSheng, Kennedy Pamela J, Nestler Eric J   Epigenetics of the depressed brain: role of histone acetylation and methylation Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013; 38(1): 124-37.
Kennedy Pamela J, Shapiro Matthew L   Motivational states activate distinct hippocampal representations to guide goal-directed behaviors Proceedings of the National Academy of Sciences of the United States of America, 2009; 106(26): 10805-10.
Shapiro Matthew L, Kennedy Pamela J, Ferbinteanu Janina   Representing episodes in the mammalian brain Current opinion in neurobiology, 2006; 16(6): 701-9.
Kennedy Pamela J, Shapiro Matthew L   Retrieving memories via internal context requires the hippocampus The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004; 24(31): 6979-85.