Image of the Month
Synaptic mGluR1-mediated Ca2+ release is significantly increased in SCA2 mice. Purkinje neuron filled with calcium indicator OGB1 & Alexa594. Second pipette with Alexa 594 placed in dendritic region to minimally stimulate Parallel fiber synaptic inputs. Local re-gion of [Ca2+] rise near the tip of the stimulating electrode (green).
By: Meera Pratap, Stefan Pulst and Tom Otis